Review Article
... The virulence of bacteria, their capacity to cause disease, is generally dependent on the expression of a variety of properties which create a complex series of interactions between the invading pathogen and a susceptible host. Different factors may be required at different stages of infection : ini ...
... The virulence of bacteria, their capacity to cause disease, is generally dependent on the expression of a variety of properties which create a complex series of interactions between the invading pathogen and a susceptible host. Different factors may be required at different stages of infection : ini ...
Glutathione S-transferase copy number variation alters lung gene expression M.W. Butler*
... Labeling Kit, followed by additional clean-up and quantification of the biotin-labelled copy (c)RNA yield using a spectrophotometer (all reagents from Affymetrix). In accordance with Affymetrix protocols, the test microarrays were first hybridised and, if quality control was acceptable, hybridisatio ...
... Labeling Kit, followed by additional clean-up and quantification of the biotin-labelled copy (c)RNA yield using a spectrophotometer (all reagents from Affymetrix). In accordance with Affymetrix protocols, the test microarrays were first hybridised and, if quality control was acceptable, hybridisatio ...
Long Noncoding RNA as a Regulator for Transcription
... analyses of RNA polymerase II indicate that its major function is the precise initiation and elongation of protein-coding genes, early studies showed that RNA polymerase II possesses the ability to catalyze randomly initiated transcription from a calf thymus DNA or other crude DNA fractions as a tem ...
... analyses of RNA polymerase II indicate that its major function is the precise initiation and elongation of protein-coding genes, early studies showed that RNA polymerase II possesses the ability to catalyze randomly initiated transcription from a calf thymus DNA or other crude DNA fractions as a tem ...
Probing the evolution of appendage specialization by
... explanation is that there may be weak or transient PhUbx expression in Mxp/T1 that was previously overlooked. Careful examination of PhUbx expression in the anterior thorax found no evidence for such expression, beyond expression in posterior T1 in the neuroectoderm (21). In addition, this explanati ...
... explanation is that there may be weak or transient PhUbx expression in Mxp/T1 that was previously overlooked. Careful examination of PhUbx expression in the anterior thorax found no evidence for such expression, beyond expression in posterior T1 in the neuroectoderm (21). In addition, this explanati ...
CRISPR-Cas9 Mouse Toolbox
... enable the rapid ligation of annealed and phosphorylated oligos designed based on the target site sequence (20bp). The cloning protocol can be found below. ...
... enable the rapid ligation of annealed and phosphorylated oligos designed based on the target site sequence (20bp). The cloning protocol can be found below. ...
Real time PCR based determination of gene copy numbers in
... Nevertheless, recent studies reported even higher expression rates when the target gene was under the control of deletion variants of the AOX1 promoter [3] or in some cases also with the constitutive glyceraldehyde-3-phosphate dehydrogenase promoter (PGAP) [4]. Depending on the target gene, high cop ...
... Nevertheless, recent studies reported even higher expression rates when the target gene was under the control of deletion variants of the AOX1 promoter [3] or in some cases also with the constitutive glyceraldehyde-3-phosphate dehydrogenase promoter (PGAP) [4]. Depending on the target gene, high cop ...
Am I a Warrior? - Erasmus University Thesis Repository
... Cortisol is a steroid hormone which is produced in the zona fasciculate of the adrenal cortex as a response to any form of stress. Both physical stress and psychological stress causes the release of this hormone. This is why Cortisol is also called the stress hormone. Physical and psychological stre ...
... Cortisol is a steroid hormone which is produced in the zona fasciculate of the adrenal cortex as a response to any form of stress. Both physical stress and psychological stress causes the release of this hormone. This is why Cortisol is also called the stress hormone. Physical and psychological stre ...
Three epigenetic information channels and their different roles in
... classified together mechanistically – for example as being based on DNA methylation – will have quite different evolutionary consequences depending upon the way in which they are deployed. Amongst those transgenerational epigenetic effects that are adaptive and have been selected, we distinguish bet ...
... classified together mechanistically – for example as being based on DNA methylation – will have quite different evolutionary consequences depending upon the way in which they are deployed. Amongst those transgenerational epigenetic effects that are adaptive and have been selected, we distinguish bet ...
Involvement of Pax6 and Otx2 in the forebrain
... In this study, we describe the involvement of the homeodomain containing transcription factors Otx2 and Pax6 in ANF gene regulation. Otx2 is known for its specific function as a transcriptional regulator during forebrain and midbrain development in vertebrates (Boncinelli and Morgan, 2001). In all e ...
... In this study, we describe the involvement of the homeodomain containing transcription factors Otx2 and Pax6 in ANF gene regulation. Otx2 is known for its specific function as a transcriptional regulator during forebrain and midbrain development in vertebrates (Boncinelli and Morgan, 2001). In all e ...
- bioRxiv
... In contrast to work with single cell organisms, the impact of gene dosage on expression variability in metazoans is less well studied. However, a full understanding of the effect of gene copy deletions is fundamental for better understanding of diseases that originate from gene copy number changes. ...
... In contrast to work with single cell organisms, the impact of gene dosage on expression variability in metazoans is less well studied. However, a full understanding of the effect of gene copy deletions is fundamental for better understanding of diseases that originate from gene copy number changes. ...
Fulltext PDF - Indian Academy of Sciences
... methylation pattern acquired in response to abiotic or biotic stress is often inherited over one to several subsequent generations. Cytosine methylation marks affect physiological functions of plants via their effect(s) on gene expression levels. They also repress transposable elements that are abun ...
... methylation pattern acquired in response to abiotic or biotic stress is often inherited over one to several subsequent generations. Cytosine methylation marks affect physiological functions of plants via their effect(s) on gene expression levels. They also repress transposable elements that are abun ...
Real – time fMRI
... Summary and discussion • The aim of this study was to find out whether genetic variants affecting BMI in normal population are protective against ANR • Results show that this is not the case • Additionally, except for one, SNPs influencing BMI in normal population didn’t predict BMI in the ANR grou ...
... Summary and discussion • The aim of this study was to find out whether genetic variants affecting BMI in normal population are protective against ANR • Results show that this is not the case • Additionally, except for one, SNPs influencing BMI in normal population didn’t predict BMI in the ANR grou ...
Class17 1-31 Win16 Cell Cycle Notes
... Draw E2F, and include binding sites for other molecules. -Where are they in relation to each other? Does E2F binds to Rb or promoters more tightly? Why is E2F called a ‘transcription factor’? ...
... Draw E2F, and include binding sites for other molecules. -Where are they in relation to each other? Does E2F binds to Rb or promoters more tightly? Why is E2F called a ‘transcription factor’? ...
Mapping the Genetic Architecture of Gene Expression in Human Liver
... Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order disease traits. Therefore, identifying the molecular phenotypes that vary in response to changes in DNA a ...
... Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order disease traits. Therefore, identifying the molecular phenotypes that vary in response to changes in DNA a ...
The concept of mixed state in bipolar disorder
... propose more adequate diagnostic criteria. At present, in the absence of widely-accepted opinion, the literature is filled with a variety of terms that are often interchangeable and used inappropriately to indicate similar concepts: these include mixed state, mixed mania, dysphoric mania and mania w ...
... propose more adequate diagnostic criteria. At present, in the absence of widely-accepted opinion, the literature is filled with a variety of terms that are often interchangeable and used inappropriately to indicate similar concepts: these include mixed state, mixed mania, dysphoric mania and mania w ...
Tutorial: RNA-Seq Analysis Part II (Tracks): Non-Specific
... Figure 10: The dot in the scatter plot corresponding to the gene "Rps13" and the corresponding region in the trackm list "zoomed-to-selection". area showing the visible reads by grabbing at the bottom of the track's editor and dragging it downwards. You will get a view similar to that in figure 11. ...
... Figure 10: The dot in the scatter plot corresponding to the gene "Rps13" and the corresponding region in the trackm list "zoomed-to-selection". area showing the visible reads by grabbing at the bottom of the track's editor and dragging it downwards. You will get a view similar to that in figure 11. ...
Interplay between copy number, dosage compensation and
... In contrast to work with single cell organisms, the impact of gene dosage on expression variability in metazoans is less well studied. However, a full understanding of the effect of gene copy deletions is fundamental for better understanding of diseases that originate from gene copy number changes. ...
... In contrast to work with single cell organisms, the impact of gene dosage on expression variability in metazoans is less well studied. However, a full understanding of the effect of gene copy deletions is fundamental for better understanding of diseases that originate from gene copy number changes. ...
- SciTech Connect
... other mechanisms. For example, parents often supply their offspring with resources to enhance their chances of survival; these resources can include nutrition, parental care, and other assistance. The quality and quantity of these parentally supplied resources can transmit information to the next ge ...
... other mechanisms. For example, parents often supply their offspring with resources to enhance their chances of survival; these resources can include nutrition, parental care, and other assistance. The quality and quantity of these parentally supplied resources can transmit information to the next ge ...
1Department of Hematology, 2Department of Dermatology, Leiden
... was stable, but could be corrected by enforced PIGH expression by retroviral transduction Loss of PIGH mRNA was not due to DNA mutations, but possibly due to epigenetic down regulation by methylation of the promoter region Combining epigenetic modulatory drugs with alemtuzumab might be a promising ...
... was stable, but could be corrected by enforced PIGH expression by retroviral transduction Loss of PIGH mRNA was not due to DNA mutations, but possibly due to epigenetic down regulation by methylation of the promoter region Combining epigenetic modulatory drugs with alemtuzumab might be a promising ...