Quantitative genetics of gene expression during fruit fly - EMBL-EBI
... to model organisms kept in the laboratory, where breeding patterns and environmental conditions can be tightly controlled. This enables the study of gene regulation not only in different environmental conditions, but also in different stages of an animal’s life. A crucial stage of life is embryonic ...
... to model organisms kept in the laboratory, where breeding patterns and environmental conditions can be tightly controlled. This enables the study of gene regulation not only in different environmental conditions, but also in different stages of an animal’s life. A crucial stage of life is embryonic ...
Identification of Genetic and Epigenetic Risk Factors for Psoriasis
... indicating that other genetic effects and environmental triggers are important. In order to identify novel susceptibility genes of PS and PsA, I performed the first large scale genome wide association scan for psoriasis susceptibility loci using 233 cases and 519 controls. It revealed that genes of ...
... indicating that other genetic effects and environmental triggers are important. In order to identify novel susceptibility genes of PS and PsA, I performed the first large scale genome wide association scan for psoriasis susceptibility loci using 233 cases and 519 controls. It revealed that genes of ...
MiRNA_GO_Meeting_August2015
... Co-IP plus change in mRNA levels • Validated other no evidence of direct action, but levels of mRNA are affected in response to miRNA, e.g. Western, qPCR ...
... Co-IP plus change in mRNA levels • Validated other no evidence of direct action, but levels of mRNA are affected in response to miRNA, e.g. Western, qPCR ...
... Figure 2 (A) Developmental imprinting pattern of Kcnq1. Allele-specific expression of Kcnq1 as assayed by reverse transcription (RT)-PCR and restriction digest with NlaIII on E10.5, 11.5, 12.5, 13.5, 14.5, 16.5 and neonatal heart (nnH) from F1 hybrid B6(CAST7) × C57BL/6J crosses. Digestion products ...
Deciphering the developmental program in the ascidian
... Sox17, which belongs to a family of transcription factors that contain the high mobility group box found in the sex-determining region Y gene. It is possible that the differences between the frog and zebrafish are caused by a simple technical artifact. However, it is also probable that in these spec ...
... Sox17, which belongs to a family of transcription factors that contain the high mobility group box found in the sex-determining region Y gene. It is possible that the differences between the frog and zebrafish are caused by a simple technical artifact. However, it is also probable that in these spec ...
Influencing Factors of Adolescent Girl`s
... emotional maladjustment [7] and an adult’s somatization disorder [8]. According to DSM-Ⅳ-TR(American Psychiatric Association, 2000) somatization disorder usually occurs in teenagers, and it can continue forever without treatment. Therefore, it is important to discover and actively treat somatization ...
... emotional maladjustment [7] and an adult’s somatization disorder [8]. According to DSM-Ⅳ-TR(American Psychiatric Association, 2000) somatization disorder usually occurs in teenagers, and it can continue forever without treatment. Therefore, it is important to discover and actively treat somatization ...
Bruce Rubin
... Expectorants are defined as medications that are taken to improve the ability to expectorate purulent secretions. This term is now taken to mean medications that increase airway water or the volume of airway secretions. The most commonly used of these are simple hydration including both bland aeroso ...
... Expectorants are defined as medications that are taken to improve the ability to expectorate purulent secretions. This term is now taken to mean medications that increase airway water or the volume of airway secretions. The most commonly used of these are simple hydration including both bland aeroso ...
brief psychosocial intervention (bpi)
... can contribute to the planned intention to treat analysis. ...
... can contribute to the planned intention to treat analysis. ...
Flexible expressed region analysis for RNA
... made it possible to characterize the transcriptomes of a diverse range of experimental systems, including human tissues (1–3), cell lines (4,5) and model organisms (6,7). The goal of many experiments involves identifying differential expression with respect to disease, development or treatment. In e ...
... made it possible to characterize the transcriptomes of a diverse range of experimental systems, including human tissues (1–3), cell lines (4,5) and model organisms (6,7). The goal of many experiments involves identifying differential expression with respect to disease, development or treatment. In e ...
Molecular Design of Expression Systems
... upon interaction with a corresponding specific repressor protein. This interaction may be influenced by adjusting the temperature (ts regulatory mutant) or the composition (inducer or corepressor concentration) of the growth medium in order to switch from low to high promoter activity. Limitations o ...
... upon interaction with a corresponding specific repressor protein. This interaction may be influenced by adjusting the temperature (ts regulatory mutant) or the composition (inducer or corepressor concentration) of the growth medium in order to switch from low to high promoter activity. Limitations o ...
Retrograde Gbb signaling through the Bmp type 2
... neurosecretory cells is therefore important for understanding how NMJ activity may be modulated by the neuroendocrine system. Within the vertebrate nervous system, members of the bone morphogenetic protein (Bmp) subgroup of TGFβ and their cognate receptors have been implicated in controlling several ...
... neurosecretory cells is therefore important for understanding how NMJ activity may be modulated by the neuroendocrine system. Within the vertebrate nervous system, members of the bone morphogenetic protein (Bmp) subgroup of TGFβ and their cognate receptors have been implicated in controlling several ...
Regulation of Bacterial Conjugation in Microaerobiosis by
... The virulence plasmid of Salmonella enterica (pSLT) is an F-like conjugative plasmid. High rates of pSLT transfer occur in the mammalian gut, a microaerobic environment. In this study, we describe genetic screens for host-encoded activators and repressors of the transfer operon (tra) of pSLT. We sho ...
... The virulence plasmid of Salmonella enterica (pSLT) is an F-like conjugative plasmid. High rates of pSLT transfer occur in the mammalian gut, a microaerobic environment. In this study, we describe genetic screens for host-encoded activators and repressors of the transfer operon (tra) of pSLT. We sho ...
Deletion of a conserved noncoding sequence in Plzf intron leads to
... we identified 70 sequence variants (Fig. 4A and Supp. Table S1). There are 47 substitutions or SNPs in strict sense; 22 small indels (insertions and deletions up to 14 bp), from which 12 appear to be in a single base “run” and 5 in more complex ...
... we identified 70 sequence variants (Fig. 4A and Supp. Table S1). There are 47 substitutions or SNPs in strict sense; 22 small indels (insertions and deletions up to 14 bp), from which 12 appear to be in a single base “run” and 5 in more complex ...
Epigenetic Control of Apomixis
... regions of chromosomes and the repetitive elements are heavily methylated. The level of 5-mC is determined by DNA methylation and demethylation processes. Methylation can be removed from the DNA by active and/or passive mechanisms. Promiscuous methylation requires to be pruned by demethylases to cre ...
... regions of chromosomes and the repetitive elements are heavily methylated. The level of 5-mC is determined by DNA methylation and demethylation processes. Methylation can be removed from the DNA by active and/or passive mechanisms. Promiscuous methylation requires to be pruned by demethylases to cre ...
development, the Linker histone H1 is essential for Drosophila
... However, its elimination by gene inactivation led to partially decondensed chromatin, supporting an in vivo role for H1 in chromatin folding. Mammals express at least eight nonallelic H1 subtypes that differ in their expression during development. Although none of the eight individual subtypes appea ...
... However, its elimination by gene inactivation led to partially decondensed chromatin, supporting an in vivo role for H1 in chromatin folding. Mammals express at least eight nonallelic H1 subtypes that differ in their expression during development. Although none of the eight individual subtypes appea ...
Waleed Abdellatief Abd elhleem _paper manuscript
... genetic and environmental factors. The disease is characterized by autoantibody production, abnormalities of immune inflammatory system function and inflammatory manifestation in several organs. However, the complete etiology of SLE is still unknown [1,2]. Consistent with the systemic nature of SLE, ...
... genetic and environmental factors. The disease is characterized by autoantibody production, abnormalities of immune inflammatory system function and inflammatory manifestation in several organs. However, the complete etiology of SLE is still unknown [1,2]. Consistent with the systemic nature of SLE, ...
trans - bioRxiv
... irrespective of their effect sizes, consistent with a hypothesis that they represent rate-limiting factors in ...
... irrespective of their effect sizes, consistent with a hypothesis that they represent rate-limiting factors in ...