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The Arabidopsis NAC Transcription Factor VNI2
The Arabidopsis NAC Transcription Factor VNI2

... et al., 2010a). The Arabidopsis NAP (NAC-LIKE, ACTIVATED BY AP3/PI) gene is transcriptionally regulated during senescing process in Arabidopsis leaves (Guo and Gan, 2006). Whereas the NAP-deficient mutant exhibits delayed leaf senescence, premature senescence is induced in the transgenic plants over ...
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... 14:30-15:00 Paul Vrana -University of California, Irvine, U.S.A. – “A system for assessing the effects of natural genetic variation on genomic imprinting.” ...
Grandroundsepistaxis
Grandroundsepistaxis

... Acquired inhibitors (cont.) Lupus anticoagulant: Antibodies against protein-phospholipid complexes. May interfere with assays for factors VIII, IX, XI and XII without causing a true decrease in factor levels In adults, it may be associated with spontaneous abortion, and thromboembolism. In the pedi ...
– findings from cross-species Anxiety genetics genome-wide approaches
– findings from cross-species Anxiety genetics genome-wide approaches

... Anxiety disorders are complex diseases, which often occur in combination with major depression, alcohol use disorder, or general medical conditions. Anxiety disorders were the most common mental disorders within the EU states in 2010 with 14% prevalence. Anxiety disorders are triggered by environmen ...
Maintenance of DNA Methylation during the Arabidopsis Life Cycle
Maintenance of DNA Methylation during the Arabidopsis Life Cycle

... whether the mode of regulation of FWA imprinting could apply to other imprinted genes. Regulation of MEA imprinting has been analyzed, but as detailed below, the mechanism controlling MEA imprinting is still unclear. DME is also essential for MEA transcriptional activation (Choi et al., 2002), and m ...
Males with MECP2 Mutations
Males with MECP2 Mutations

... MECP2 gene. 3. MECP2-related severe neonatal encephalopathy: Males that have one of the mutations that are typically seen in Rett syndrome usually present with earlier onset and more severe symptoms than females. Again, this is because this mutation in the MECP2 gene is affecting all the cells in th ...
Males with MECP2 Mutations
Males with MECP2 Mutations

... with the mutation is active and in other cells the MECP2 gene without the mutation is active. In females with Rett syndrome this means that roughly half of their cells have a normally functioning MECP2 gene and half their cells have a MECP2 gene with a mutation present that is not functioning no ...
Jacobs Journal of Neurology and Neuroscience
Jacobs Journal of Neurology and Neuroscience

... cholesterol were reported as well [30,31]. Most of the above cited publications concerning association anemia/depression or cholesterol/depression did not evaluate anxiety symptoms. Papakostas and colleagues [17] in their review summarized the results of eight studies of anxiety effects on cholester ...
Genetic or epigenetic difference causing discordance between
Genetic or epigenetic difference causing discordance between

... antisense RNA gene, KCNQ1OT1 (KCNQ1-overlapping transcript 1), which is also regulated by imprinting. Among five pairs of MZ twins discordant for BWS, lack of DNA methylation of KCNQ1OT1 in fibroblasts was observed only in the affected twins.38 Thus, loss of imprinting is the cause of BWS in these c ...
Self-esteem from a clinical perspective
Self-esteem from a clinical perspective

... eating disorders involves the overvaluing of body shape on self-esteem. This view suggests that individuals with self-esteem contingencies based on body shape will be at risk for eating disorders. Consistent with this perspective there is evidence that females who base their selfesteem on body shape ...
Light and temperature affect the expression of two candidate genes
Light and temperature affect the expression of two candidate genes

pSAT vectors: a modular series of plasmids for autofluorescent
pSAT vectors: a modular series of plasmids for autofluorescent

Effects of cadmium on the regulation of antioxidant enzyme activity
Effects of cadmium on the regulation of antioxidant enzyme activity

Regulation of phenylalanine biosynthesis in Escherichia coli K
Regulation of phenylalanine biosynthesis in Escherichia coli K

... chromosome; pheR mutants acquired the wild-type phenotype when either F117 (which covers the 93-min region) or F116 (which covers min 59 to 65) was introduced into the cell. A rifampin resistance mutation, rpoB366, was found to derepress transcription of the pheA operon. pheR and rpoB366 affected tw ...
The role of free radicals and antioxidants in
The role of free radicals and antioxidants in

... between the prooxidants and antioxidants, a state of oxidative stress is initiated. Free radicals have a dual role in the reproductive tract. They are also key signal molecules modulating various reproductive functions. Free radicals can influence the oocytes, sperm, and embryos in their microenviro ...
Characterization and regulation of the bovine stearoyl-CoA desaturase gene promoter
Characterization and regulation of the bovine stearoyl-CoA desaturase gene promoter

The Mycobacterium tuberculosis katG promoter region contains a
The Mycobacterium tuberculosis katG promoter region contains a

Rett syndrome: clinical correlates of the newly discovered gene
Rett syndrome: clinical correlates of the newly discovered gene

... The recent identification of mutations in the gene, MECP2, in girls with Rett syndrome (RS) firmly establishes the molecular genetic basis of this X-linked dominant disorder. This discovery, with ramifications far beyond establishing the gene for RS, represents a dramatic conclusion to an intensive, ...
Sarah Pulliam
Sarah Pulliam

... both young and old mice. Blasco et al. concluded that the s-Arf/p53 mice live longer due to an antioxidant affect created when both the Arf and p53 genes are over expressed at the same time. In another study, Pinkston, et al. found the same results in Caenorhabditis elegans, a nematode worm. Just a ...
Analysis of the histone H3 gene family in Arabidopsis and
Analysis of the histone H3 gene family in Arabidopsis and

The bovine papillomavirus type 4 long control region contains an
The bovine papillomavirus type 4 long control region contains an

... nature of these enhancer elements. Bovine papillomavirus type 4 (BPV-4) is a mucosal epitheliotropic papillomavirus and is a causative agent of alimentary canal carcinoma in cattle (Campo et al., 1994). Like HPV-16 and -18, the LCR of BPV-4 controls the expression of the transforming genes of the vi ...
association study of 37 genes suggests involvement of DDC
association study of 37 genes suggests involvement of DDC

... tomography (PET) have shown abnormal asymmetry of serotonin synthesis in frontal, temporal and parietal cortex in autistic individuals compared to controls (Chandana et al. 2005). In addition, the dopaminergic activity seems to be altered in the anterior, medial and prefrontal cortex of autistic ind ...
Construction and Characterization of a Highly Regulable Expression
Construction and Characterization of a Highly Regulable Expression

... A number of different expression vectors have been developed to facilitate the regulated overproduction of proteins in Escherichia coli and related bacteria. Some of the more popular ones include pKK223-3, pKK233-2, pTrc99A, and the pET family of expression vectors. These vectors were designed to be ...
Gene Regulatory Network of Ikaros in T cell development and
Gene Regulatory Network of Ikaros in T cell development and

... risks of relapse of leukemia and poor outcome of therapy. However, it remains unclear about the gene regulatory network associated with Ikaros. How exactly the transcription of Ikaros itself is regulated? Ikaros can positively or negatively regulate its target genes, and how Ikaros' activity is regu ...
Construction of a pBAD24 Vector Containing σ32 : Restoration of
Construction of a pBAD24 Vector Containing σ32 : Restoration of

... Many regulatory elements in Escherichia coli that mediate a wide array of responses when subjected to external stress have been progressively discovered and characterized. One of many external stresses that induce a specific response in E. coli is heat shock. This response is largely controlled by σ ...
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Epigenetics of depression

Depression is a serious behavioral disorder causing long lasting feelings of sadness and loss of interest. One form of depression is Major Depressive Disorder (MDD), in which symptoms of depression are present most days a week for 2 weeks or longer. Depression affects a large aspect of day-to-day activities such as thought process, sleep, and appetite. It can be accompanied by anxiety and decreased energy. According to the World Health Organization, depression affects about 350 million people worldwide and is the major cause of disability. Depression can be caused by the interaction of environmental and genetic factors. These factors include epigenetic modification of the genome in which there is a persistent change in gene expression without a change in the actual DNA sequence.
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