Effects of adenovirus delivered Flt
... While the main route of fatty acid metabolism is through beta-oxidation, some minor metabolic pathways such as omega oxidation also contribute to the metabolism of fatty acids and other molecules. Omega oxidation occurs in the endoplasmic reticulum rather than the mitochondria, the site of beta-ox ...
... While the main route of fatty acid metabolism is through beta-oxidation, some minor metabolic pathways such as omega oxidation also contribute to the metabolism of fatty acids and other molecules. Omega oxidation occurs in the endoplasmic reticulum rather than the mitochondria, the site of beta-ox ...
Regulation of 6sg expression site transcription and switching in
... promoter manipulations at 6sg expression sites (ES) and examination of the behavior of ES promoters in ectopic locations both within the ES and at other loci. In summary, ES promoter sequences inserted into non-transcribed rRNA spacers are generally inactive, or have low activity, in bloodstream and ...
... promoter manipulations at 6sg expression sites (ES) and examination of the behavior of ES promoters in ectopic locations both within the ES and at other loci. In summary, ES promoter sequences inserted into non-transcribed rRNA spacers are generally inactive, or have low activity, in bloodstream and ...
The CpG island methylator phenotype (CIMP) in
... general key mechanism that is operative in normal tissues and has an important role in the preservation of genomic stability, embryonic development, and tissue differentiation (17). CpG (cytosine preceding guanine) islands are regions within the genome that are common in promoter sites rich in CpG d ...
... general key mechanism that is operative in normal tissues and has an important role in the preservation of genomic stability, embryonic development, and tissue differentiation (17). CpG (cytosine preceding guanine) islands are regions within the genome that are common in promoter sites rich in CpG d ...
Associations between childhood maltreatment and emotion processing biases in major
... is evidence for a lack of attentional bias toward positive stimuli [45]. Few studies illuminated the relationship between childhood maltreatment and biased attention to sad stimuli, whereas it seems important to use stimuli relevant for depression when investigating vulnerability to this disorder. G ...
... is evidence for a lack of attentional bias toward positive stimuli [45]. Few studies illuminated the relationship between childhood maltreatment and biased attention to sad stimuli, whereas it seems important to use stimuli relevant for depression when investigating vulnerability to this disorder. G ...
Molecular and Cellular Biology, September 2000, p
... molecules involved in this cascade interact with different regulatory pathways, leading to a general control of chromatin remodeling during cell differentiation. Indeed, through the control of a specific group of genes encoding chromatin-associated proteins (such as H10), these molecules may regulat ...
... molecules involved in this cascade interact with different regulatory pathways, leading to a general control of chromatin remodeling during cell differentiation. Indeed, through the control of a specific group of genes encoding chromatin-associated proteins (such as H10), these molecules may regulat ...
Interactive Visualization of Gene Regulatory Networks with
... to a researcher [6]. As part of this effort, we have developed an application for visualization of gene regulatory networks. Gene regulatory networks can be represented by graphs, in which nodes represent genes, and edges represent interactions between a gene product (a regulator protein) and its ta ...
... to a researcher [6]. As part of this effort, we have developed an application for visualization of gene regulatory networks. Gene regulatory networks can be represented by graphs, in which nodes represent genes, and edges represent interactions between a gene product (a regulator protein) and its ta ...
Mutations in SIN4 and RGR1 Cause Constitutive Expression of MAL
... SIN4 and RGR1 Repress MAL Basal Expression open reading frame under the control of the MAL61 promoter was constructed as follows. Plasmid YIp365-I61 (Danzi et al. 2000) carrying the MAL61 promoter was digested with EcoRI and Sal I to liberate a 0.9-kb fragment containing base pairs ⫺874 to ⫺1 of th ...
... SIN4 and RGR1 Repress MAL Basal Expression open reading frame under the control of the MAL61 promoter was constructed as follows. Plasmid YIp365-I61 (Danzi et al. 2000) carrying the MAL61 promoter was digested with EcoRI and Sal I to liberate a 0.9-kb fragment containing base pairs ⫺874 to ⫺1 of th ...
Differential chromatin packaging of genomic
... and one is the CpG methylation. Almost all imprinted genes have sequence elements that are methylated on only one of the two parental alleles. The differential methylation is a signal that leads to an inactive state of chromatin probably through binding to methyl-CpG-binding proteins, such as MeCP2, ...
... and one is the CpG methylation. Almost all imprinted genes have sequence elements that are methylated on only one of the two parental alleles. The differential methylation is a signal that leads to an inactive state of chromatin probably through binding to methyl-CpG-binding proteins, such as MeCP2, ...
Journal Club Pack - Circulation Research
... although we have previously shown that phenotypic switching of cultured SMC is dependent on Krupplelike factor (KLF)4. Objective: The goals of the present studies were to ascertain if (1) injury-induced repression of SM22α gene after vascular injury is mediated through KLF4 binding to the G/C Repres ...
... although we have previously shown that phenotypic switching of cultured SMC is dependent on Krupplelike factor (KLF)4. Objective: The goals of the present studies were to ascertain if (1) injury-induced repression of SM22α gene after vascular injury is mediated through KLF4 binding to the G/C Repres ...
- Lab Fabiana Perocchi
... Figure 1 Measuring allelic expression on a tiling array. (A) The array contains 25-mer probes (black and blue) that tile both strands of the genome of S288c with a probe offset of 8 bp and a 4-bp shift between the two strands. The array also contains probes (red) complementary to the YJM789 sequence ...
... Figure 1 Measuring allelic expression on a tiling array. (A) The array contains 25-mer probes (black and blue) that tile both strands of the genome of S288c with a probe offset of 8 bp and a 4-bp shift between the two strands. The array also contains probes (red) complementary to the YJM789 sequence ...
Smchd1 regulates a subset of autosomal genes subject to
... Background: Smchd1 is an epigenetic modifier essential for X chromosome inactivation: female embryos lacking Smchd1 fail during midgestational development. Male mice are less affected by Smchd1-loss, with some (but not all) surviving to become fertile adults on the FVB/n genetic background. On other ...
... Background: Smchd1 is an epigenetic modifier essential for X chromosome inactivation: female embryos lacking Smchd1 fail during midgestational development. Male mice are less affected by Smchd1-loss, with some (but not all) surviving to become fertile adults on the FVB/n genetic background. On other ...
Serotonergic Function, Two-Mode Models of Self
... University of Miami Evidence from diverse literatures supports the viewpoint that two modes of self-regulation exist, a lower-order system that responds quickly to associative cues of the moment and a higher-order system that responds more reflectively and planfully; that low serotonergic function i ...
... University of Miami Evidence from diverse literatures supports the viewpoint that two modes of self-regulation exist, a lower-order system that responds quickly to associative cues of the moment and a higher-order system that responds more reflectively and planfully; that low serotonergic function i ...
DNA cytosine methylation in plant development
... (Bird, 2002). A striking difference in the cytosine methylation patterns in plants from those in animals is that although methylation is predominantly occurring at the CG dinucleotides in plants, it is not confined to these sites; instead, methylation also occurs at CHG (where H is A, C or T) and as ...
... (Bird, 2002). A striking difference in the cytosine methylation patterns in plants from those in animals is that although methylation is predominantly occurring at the CG dinucleotides in plants, it is not confined to these sites; instead, methylation also occurs at CHG (where H is A, C or T) and as ...
Analysis of inbreeding depression in the first litter size of mice in a long
... Depression was estimated for 20 subsets, differing by the period in which inbreeding was considered as “new”. In 15 of these, “new” inbreeding was estimated to have a higher depression, compared to “old” inbreeding. The estimated depression ranged from –11.53 to – 0.79 for the “new” inbreeding and f ...
... Depression was estimated for 20 subsets, differing by the period in which inbreeding was considered as “new”. In 15 of these, “new” inbreeding was estimated to have a higher depression, compared to “old” inbreeding. The estimated depression ranged from –11.53 to – 0.79 for the “new” inbreeding and f ...
Two ParaHox genes, SpLox and SpCdx, interact to
... the posterior endoderm in the formation of a functional gut Alison G. Cole1,*, Francesca Rizzo1,*, Pedro Martinez2, Montserrat Fernandez-Serra1 and Maria I. Arnone1,† We report the characterization of the ortholog of the Xenopus XlHbox8 ParaHox gene from the sea urchin Strongylocentrotus purpuratus, ...
... the posterior endoderm in the formation of a functional gut Alison G. Cole1,*, Francesca Rizzo1,*, Pedro Martinez2, Montserrat Fernandez-Serra1 and Maria I. Arnone1,† We report the characterization of the ortholog of the Xenopus XlHbox8 ParaHox gene from the sea urchin Strongylocentrotus purpuratus, ...
