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Chapter 16 (Part 3)
Chapter 16 (Part 3)

... • Biosynthesis uses NADPH/NADP+; breakdown uses NADH/NAD+ ...
Tymoczko, Biochemistry: A Short Course 3e, Launchpad
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... 1. Lipid molecules are said to be amphipathic, meaning that a. they have asymmetric carbons and can exist in left- and right-handed forms. b. they have a dual nature with part of the molecule being hydrophobic and the other part hydrophilic. c. they are capable of moving rapidly from one side of a l ...
Fatty Acid Oxidation
Fatty Acid Oxidation

... This lecture links defects in catabolism of lipids to a variety of pathological states. Following this lecture students should understand that ...
Fatty Acid Synthesis
Fatty Acid Synthesis

... De novo synthesis of FAs  In mammals fatty acid synthesis occurs primarily in the cytosol of the liver and adipose tissues .It also occurs in mammary glands during lactation.  Acetyl-CoA is the starting material for FA synthesis. However, most acetyl-CoA in mitochondria(from the breakdown of suga ...
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... Alcohol fermentation is carried a number of bacteria & yeasts. Organisms that produce lactic acid other acids or alcohols are known as heterolactic (or heterofermentative); often use the pentose phosphate pathway. Glucose + ADP + P —>Lactic acid + Ethanol + CO2+ ATP ...
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... Organic: contains carbon and hydrogen ◦ All living things contain carbon (C), hydrogen (H), oxygen (O), nitrogen (N), phosphorus (P) and Sulfur (S)  Monomer: created when C,H,O, N, P bond together to form small molecules  Polymer: large compounds that are formed by joining monomers together ...
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... 28. When glucose labeled with a 14C at C-2 passes through glycolysis, the glyceraldehyde 3phosphate that is produced from it still contains the radioactive carbon atom. Draw the structure of glyceraldehyde 3-phosphate, and circle the atom(s) that would be radioactive. ...
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...  Provides a STORED source of energy for your body to use when it needs it  Triglycerides = 1 glycerol + 3 fatty acids  Saturated – solid (no double bonds between carbon atoms), animal fats (like lard and butter)  Unsaturated – liquid (like fish and vegetable oils), double or triple bond between ...
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... germinated seeds of this tree for food uses is not known. This study reports some biochemical changes during seed germination associated with antioxidant activity and the mobilization of lipids and phenolics. Lipid content decreased, whereas the dominant fatty acids did not change significantly. The ...
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... -oxidation is a minor pathway and is brought about by cytochrome P450 in the endoplasmic reticulum. CH3 group is converted to a -CH2OH group that subsequently is oxidized to -COOH, thus forming a dicarboxylic acid. They subsequently undergo ß-oxidation and are excreted in the urine. ...
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... A) Carnitine is required to transport fatty acyl CoA into the mitochondrial matrix for β oxidation. The inhibition of fatty acid transport caused by a deficiency in carnitine diminishes energy production from fats for muscular work. Excess fatty acyl-CoA can be converted to triaclglycerols in the mu ...
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... • Impermeable to ions and most polar molecules to form boundaries • Create a charge difference ...
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... In 1904, Franz Knoop fed dogs labeled at their -carbon atoms of even-numbered- and odd-numbered FAs by a benzene ring and isolated the phenyl-containing metabolic products (glycine adduct) from their urine (phenylaceturic acid and hippuric acid ). ...
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03. Lipids. Classification, structure and biological role

... • The most important role of lipids is as а fuel. Thus fat is the most concentrated form in which potential energy can be stored. • Since fat is а bad conductor of heat, it provides excellent insulation. • Fat may also provide padding to protect the internal organs. • Some compounds derived from lip ...
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Molecole per la vita

... Triglycerides are lipids that are obtained by means of the esterification reaction between glycerol and fatty acids and form the fatty tissues of animals and plants. Triglycerides may be saturated or unsaturated depending on whether the hydrocarbon chains of the fatty acids contain double bonds or n ...
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Fatty acid synthesis



Fatty acid synthesis is the creation of fatty acids from acetyl-CoA and malonyl-CoA precursors through action of enzymes called fatty acid synthases. It is an important part of the lipogenesis process, which – together with glycolysis – functions to create fats from blood sugar in living organisms.
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