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PowerPoint
PowerPoint

... The AG went up by 8, so the HCO3 should go down by 8. So HCO3 should be 24 – 8 = 16 but is ...
Lipoteichoic Acid Synthesis and Function in Gram
Lipoteichoic Acid Synthesis and Function in Gram

... has significantly diverged from the LtaS enzyme. In Bacillus spp., which contain four LTA synthase enzymes, these proteins are more closely related to each other and the LtaS protein of L. monocytogenes than to LtaP. Disaccharide-containing glycolipids are often the predominant glycolipids and are pr ...
University of Groningen Mutants and homologs of
University of Groningen Mutants and homologs of

... emphasis on not only the hydrolysis reaction but also on the synthetic reaction [58]. The acylation step and the deacylation step have been described as separate steps in the reaction and it was shown that the breakdown of the acyl-enzyme is much faster than its formation implying that the rate of h ...
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... a. Methylation of Cobalamin b. Addition of the C8 carbon on purine synthesis c. Addition of the C2 carbon in purine synthesis d. Methylation of uracil to make thymidine e. Serine-glycine hydroxymethyl transferase (it makes methyl THF in reverse or uses methyl THF to make serine) 9. Describe the fola ...
Concordance of Changes in Metabolic Pathways Based
Concordance of Changes in Metabolic Pathways Based

... those known to be affected by insulin such as glucose, amino acid and lipid metabolism, Krebs cycle, and immune responses and those hitherto unknown to be altered including prostaglandin, arachidonic acid, leukotrienes, neurotransmitters, nucleotides, and anti-inflammatory responses. A significant con ...
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2 H + 1 / 2 O 2

... • Fats are digested to glycerol (used in glycolysis) and fatty acids (used in generating acetyl CoA) • Fatty acids are broken down by beta oxidation and yield acetyl CoA • An oxidized gram of fat produces more than twice as much ATP as an oxidized gram of carbohydrate ...
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Slide 1 - Annals of Internal Medicine

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... General aspects of BCAAs catabolism cells, because amino acids are little stored in free form in mammalian species. BCAAs are metabolized by skeletal muscle, liver, kidney, heart, brain and adipose tissue as an alternative energy source, or used for the biosynthesis of lipids. In humans, the BCAAs a ...
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Carbohydrate Metabolism
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... molecules, two NADH molecules are synthesized during this step. Each 1,3-bisphosphoglycerate is subsequently dephosphorylated (i.e., a phosphate is removed) by phosphoglycerate kinase into 3-phosphoglycerate. Each phosphate released in this reaction can convert one molecule of ADP into one high-ener ...
Preparation of Human Metabolites of Propranolol Using Laboratory-Evolved Bacterial Cytochromes P450
Preparation of Human Metabolites of Propranolol Using Laboratory-Evolved Bacterial Cytochromes P450

... and these may be difficult to synthesize. An alternative to chemical synthesis is to use P450s to generate the metabolites of drugs or drug candidates. Hepatic microsomes are a source of human P450s, but their limited availability and highly variable expression levels make their use in preparative-s ...
The Role of Epidermal Lipids in Cutaneous Permeability Barrier
The Role of Epidermal Lipids in Cutaneous Permeability Barrier

... The free fatty acids that are formed by phospholipid breakdown contribute to the acidification of the stratum corneum (38, 39). The pH of the outer stratum corneum and skin surface in humans and animals ranges from 5-5.5 (40). This acidic environment is very important as it regulates the activity of ...
The Emerging Role of Branched-Chain Amino Acids in Insulin
The Emerging Role of Branched-Chain Amino Acids in Insulin

... Despite the positive effects of BCAAs on metabolism, the strong association of BCAA levels with insulin resistance and metabolic syndrome suggests that increased levels of BCAAs may cause insulin resistance and T2DM, although this remains a speculation for now. The mechanism underlying that correlat ...
Kinetics and mechanisms of reactions catalyzed by
Kinetics and mechanisms of reactions catalyzed by

... Immobilized lipases are those lipases localized in a defined region of space, which is enclosed by an imaginary (or material) barrier that allows for physical separation of the enzyme from the bulk reaction medium and that is, at the same time, permeable to reactant and product molecules [7]. In add ...
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Fatty acid synthesis



Fatty acid synthesis is the creation of fatty acids from acetyl-CoA and malonyl-CoA precursors through action of enzymes called fatty acid synthases. It is an important part of the lipogenesis process, which – together with glycolysis – functions to create fats from blood sugar in living organisms.
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