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LipidMetabolism
LipidMetabolism

... Reactions involve formation of oxygencontaining rings; thus the enzymes are cyclooxygenases ...
bacterial hemoglobin proteins - ETH E-Collection
bacterial hemoglobin proteins - ETH E-Collection

Two nearly identical terpene synthases catalyze the
Two nearly identical terpene synthases catalyze the

... respectively (Table 1). Both enzymes show similar catalytic efficiencies (kcat/Km ratio) with GPP, which were slightly lower than with FPP (Table 1). Identification of AmNES/LIS in snapdragon flowers To verify the involvement of AmNES/LIS enzymes in linalool and (E)-nerolidol formation in snapdragon ...
Modulation of functional properties of bifunctional S- Adenosylmethionine decarboxylase/Ornithine decarboxylase of
Modulation of functional properties of bifunctional S- Adenosylmethionine decarboxylase/Ornithine decarboxylase of

... Sucrose, Triton X-100, EDTA, Tris ...
thèse - Université Evry Val d`Essonne
thèse - Université Evry Val d`Essonne

... proteins. mtDNA generally encodes catalytic subunits of the complexes of the respiratory chain with tRNA and rRNA components of the mitochondrial translation system, but it can also contain additional proteins; in S. cerevisiae, besides seven subunits of complexes involved in oxidative phosphorylati ...
Glyphosate pathways to modern diseases V: Amino
Glyphosate pathways to modern diseases V: Amino

... having functionality resembling the activities of cationic antimicrobial peptides [8]. A reactive side chain is attached to the nitrogen of glycine, and such units can be assembled into “peptoid” chains that in many ways resemble peptide chains, except that they are highly resistant to proteolysis. ...
Anaerobic and aerobic pathways for salvage of proximal tubules
Anaerobic and aerobic pathways for salvage of proximal tubules

... membrane components. However, there are at least two explanations for the beneficial effects afforded by provision of the substrates only during reoxygenation, and they are not mutually exclusive. One is that the same mechanisms of substrate-level phosphorylation and anaerobic respiration that preve ...
Being right on Q: shaping eukaryotic evolution
Being right on Q: shaping eukaryotic evolution

... formation is not a peripheral bacterial phenomenon anymore: it now occurs in the middle of the new organism. Secondly, alternatively using different catabolic substrates, as described above, gave rise to more ROS formation [5,6]. Why should this be so? Relative amounts of the intermediates FADH2 and ...
David Rittenberg - National Academy of Sciences
David Rittenberg - National Academy of Sciences

... was instead assigned to H. T. Clarke, chair of the Department of Biochemistry at P&S to promote biological uses of 2H. At that time one interest of Clarke’s was the possibility of demonstrating optical activity for a compound, Cab1H2H. Clarke also suggested to Rittenberg a “roving commission” to tal ...
Molecular and cellular requirements for the
Molecular and cellular requirements for the

... molecular mechanisms whereby Ca2+ either stimulates or inhibits susceptible adenylate cyclases in vitro. However, in the intact cell an additional layer of sophistication is evident whereby Ca2+ -sensitive adenylate cyclases are juxtaposed with Ca2+ -entry channels, such that the cyclases respond se ...
20 Tricarboxylic Acid Cycle
20 Tricarboxylic Acid Cycle

... biosynthetic reactions, the carbons of oxaloacetate must be replaced by anaplerotic (filling up) reactions, such as the pyruvate carboxylase reaction. The TCA cycle occurs in the mitochondrion, where its flux is tightly coordinated with the rate of the electron transport chain and oxidative phosphor ...
Role of adiponectin in the regulation of carbohydrate and lipid
Role of adiponectin in the regulation of carbohydrate and lipid

... α gene expression and increase in PPARα activity (28, α is required for transcription of many genes ...
AMP-activated protein kinase and metabolic control - HAL
AMP-activated protein kinase and metabolic control - HAL

... Physical activity is an important determinant to prevent and control T2D. Current guidelines recommend practical, regular and moderate regimens of physical activity. The multiple metabolic adaptations that occur in response to physical activity can improve glycaemic control for individuals with T2D ...
- Wiley Online Library
- Wiley Online Library

... CASQ is held within the SR and near RYR1 by luminal proteins triadin (TRDN) and junctin (ASPH). Aside from initiating contraction, Ca2+ may also play a signaling role in muscle. In some disease states, Ca2+ activates CAPN, a family of proteolytic enzymes important in muscle.23 Through the activation ...
Engineering Cytosolic Acetyl-CoA Metabolism in
Engineering Cytosolic Acetyl-CoA Metabolism in

... A Saccharomyces cerevisiae strain carrying deletions in all three pyruvate decarboxylase genes (also called Pdc negative yeast) represents a non-ethanol producing platform strain for biochemical production. However, it cannot grow on glucose as the sole carbon source due to the lack of cytosolic ace ...
Long-Term Treatment with Insulin and Retinoic Acid
Long-Term Treatment with Insulin and Retinoic Acid

Glycolysis and Gluconeogenesis
Glycolysis and Gluconeogenesis

... as all other kinases, requires Mg2⫹ (or another divalent metal ion such as Mn2⫹) for activity. The divalent metal ion forms a complex with ATP. X-ray crystallographic studies of yeast hexokinase revealed that the binding of glucose induces a large conformational change in the enzyme. Hexokinase cons ...
Organization and Integration of Large-scale Datasets for
Organization and Integration of Large-scale Datasets for

... Mycoplasma pneumoniae, one of the smallest known self-replicating organisms, is a promising model organism in systems biology when aiming to assess understanding of an entire living cell. One of the key steps towards this goal is the design of mathematical models that describe the cellular processes ...
Organization and Integration of Large
Organization and Integration of Large

... Mycoplasma pneumoniae, one of the smallest known self-replicating organisms, is a promising model organism in systems biology when aiming to assess understanding of an entire living cell. One of the key steps towards this goal is the design of mathematical models that describe the cellular processes ...
Glycogen Stores in 3T3-L1 Adipocytes Glycogen in the
Glycogen Stores in 3T3-L1 Adipocytes Glycogen in the

... cating both high infection efficiency and efficacy of the siRNA construct against PTG message levels. In parallel, the effects of the siRNA adenoviral constructs on cellular protein expression were examined. The postnuclear spin supernatant and cytosolic and glycogen-enriched pellet fractions were i ...
Regulators of Ubiquitin Dependent Protein Degradation in the
Regulators of Ubiquitin Dependent Protein Degradation in the

... Expression of CSN subunits is independent of DNA damaging agents ................ 98 ...
Is transcriptomic regulation of berry development more
Is transcriptomic regulation of berry development more

Intermediary metabolism
Intermediary metabolism

Multiple Lines of Evidence Localize Signaling
Multiple Lines of Evidence Localize Signaling

... Using GFP tagging, mitochondria have been visualized to undergo fusion, fission, and rapid movements, suggesting a dynamic interaction with components of the cytoskeleton (Sheahan et al., 2004, 2005; Logan, 2010). However, many of the specific proteins that mediate such processes remain unknown. Whi ...
High pKa variability of cysteine residues in structural databases and
High pKa variability of cysteine residues in structural databases and

... at the functional sites of proteins, where it serves a variety of structural and functional roles [1-3], including structural stabilization (disulfide bridges, metal coordination), catalysis (e.g. active site nucleophile in thiol-based oxidoreductases) and post-translational modifications (e.g. reve ...
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Biochemical cascade

A biochemical cascade (or a signaling pathway) is a series of chemical reactions which are initiated by a stimulus (first messenger) acting on a receptor that is transduced to the cell interior through second messengers (which amplify the initial signal) and ultimately to effector molecules, resulting in a cell response to the initial stimulus. At each step of the signaling cascade, various controlling factors are involved to regulate cellular actions, responding effectively to cues about their changing internal and external environments.
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