School of Biochemistry International visiting and Immunology student options
... This module considers protein structure and function, including membrane proteins, cytoskeleton, microtubules and actin and proteins of the immune system. Signal transduction pathways and associated pathological conditions important to human health make up the final portion of the module. The lectur ...
... This module considers protein structure and function, including membrane proteins, cytoskeleton, microtubules and actin and proteins of the immune system. Signal transduction pathways and associated pathological conditions important to human health make up the final portion of the module. The lectur ...
MICROBIAL PHYSIOLOGY AND BIOCHEMISTRY
... itself. On the other hand, ATP is formed by the transfer of phosphoryl group to ADP from other compounds. These compounds have a higher transfer potential than does ATP like phosphoenolpyruvate, acetyl released is then used to carry out various functions, which we have discussed in the beginning its ...
... itself. On the other hand, ATP is formed by the transfer of phosphoryl group to ADP from other compounds. These compounds have a higher transfer potential than does ATP like phosphoenolpyruvate, acetyl released is then used to carry out various functions, which we have discussed in the beginning its ...
Chapter 19 Carbohydrate Biosynthesis
... are glucogenic in mammals • The amino acids that can be converted to pyruvate or citric acid cycle intermediates are glucogenic. • Net conversion of acetyl-CoA to pyruvate (the oxidative decarboxylation of pyruvate is irreversible) or oxaloacetate does not occur in mammals, thus neither Lys and Leu ...
... are glucogenic in mammals • The amino acids that can be converted to pyruvate or citric acid cycle intermediates are glucogenic. • Net conversion of acetyl-CoA to pyruvate (the oxidative decarboxylation of pyruvate is irreversible) or oxaloacetate does not occur in mammals, thus neither Lys and Leu ...
innate immunity in c. elegans
... Mitogen‑activated protein kinase (MAPK) pathways are considered to be the most ancient signal transduction cascades in immunity, found in both animals and plants. Three MAPK cascades are implicated in C. elegans immunity. A role for the p38 MAPK pathway in C. elegans defence was first revealed in a ...
... Mitogen‑activated protein kinase (MAPK) pathways are considered to be the most ancient signal transduction cascades in immunity, found in both animals and plants. Three MAPK cascades are implicated in C. elegans immunity. A role for the p38 MAPK pathway in C. elegans defence was first revealed in a ...
Cdiff_expression_supmat_BiolInv.
... Encodes calcium-independent ABA-activated protein kinase, a member of SNF1related protein kinases (SnRK2) whose activity is activated by ionic (salt) and nonionic (mannitol) osmotic stress. Mutations disrupted ABA induction of stomatal closure as well as ABA inhibition of light-induced stomatal open ...
... Encodes calcium-independent ABA-activated protein kinase, a member of SNF1related protein kinases (SnRK2) whose activity is activated by ionic (salt) and nonionic (mannitol) osmotic stress. Mutations disrupted ABA induction of stomatal closure as well as ABA inhibition of light-induced stomatal open ...
42(5): 551-557. 2010 Insecticidal activities of essential oils from
... signal transduction has been identified in Synechocystis sp. PCC 6803. In addition, some response regulators in bacteria have been shown to be cross regulated by low molecular weight phosphorylated compounds in the absence of the cognate histidine kinase. The ability of an endogenous acetyl phosphat ...
... signal transduction has been identified in Synechocystis sp. PCC 6803. In addition, some response regulators in bacteria have been shown to be cross regulated by low molecular weight phosphorylated compounds in the absence of the cognate histidine kinase. The ability of an endogenous acetyl phosphat ...
Carbohydrates
... The Glycosidic Bond • Reaction of anomeric carbon with hydroxyl or amino group forms O-glycosidic or N-glycosidic bond ...
... The Glycosidic Bond • Reaction of anomeric carbon with hydroxyl or amino group forms O-glycosidic or N-glycosidic bond ...
Global Proteomics of the Extremophile Black Fungus Cryomyces
... mono-, di- and tri-acylglycerols, phosphotidilcholine, phosphatidylethanolamines, sterols, sterol ethers, phosphatidilrthanolamines and free fatty acids); 2) pigments with their various protective effects as e.g. melanins, carotenoids in colourless and brown-red formations; and 3) the dense cell wal ...
... mono-, di- and tri-acylglycerols, phosphotidilcholine, phosphatidylethanolamines, sterols, sterol ethers, phosphatidilrthanolamines and free fatty acids); 2) pigments with their various protective effects as e.g. melanins, carotenoids in colourless and brown-red formations; and 3) the dense cell wal ...
Probing protein function by chemical modification
... enzyme-catalyzed modifications [62–64] (See Section on Chemical Labeling in Live Cells), and by semi-synthetic approaches as described above. A recent example includes the intein-mediated incorporation of an oxyamine moiety into the C-termini of proteins, which are amenable for subsequent conjugatio ...
... enzyme-catalyzed modifications [62–64] (See Section on Chemical Labeling in Live Cells), and by semi-synthetic approaches as described above. A recent example includes the intein-mediated incorporation of an oxyamine moiety into the C-termini of proteins, which are amenable for subsequent conjugatio ...
Glycolysis - medscistudents
... Role of Fructose 2, 6-bisphosphate: It is the most regulatory factor for controlling PFK and ultimately glycolysis in the liver. ...
... Role of Fructose 2, 6-bisphosphate: It is the most regulatory factor for controlling PFK and ultimately glycolysis in the liver. ...
Chem331 Krebs Cycle
... Think of why this is a cycle vs. pathway - not because it is written that way. Oxaloacetate - only a small amount is needed - catalytic role Anapleurotic - “filling up” cycle can be used as entry and exit for production of other essential metabolites The TCA ...
... Think of why this is a cycle vs. pathway - not because it is written that way. Oxaloacetate - only a small amount is needed - catalytic role Anapleurotic - “filling up” cycle can be used as entry and exit for production of other essential metabolites The TCA ...
Brewing biochemistry
... The theoretical teaching is subdivided in two parts and supported by practicals: Biochemistry of malting and brewing: (1) barley an enzymatic reactions occurring during malting, (2) biochemical reactions during brewing. Biochemistry of fermentation: Focused on the utilization of Saccharomyces cerevi ...
... The theoretical teaching is subdivided in two parts and supported by practicals: Biochemistry of malting and brewing: (1) barley an enzymatic reactions occurring during malting, (2) biochemical reactions during brewing. Biochemistry of fermentation: Focused on the utilization of Saccharomyces cerevi ...
3 - IBperiod5
... role of allosteric sites. allosteric regulation- regulatory molecules bind on the enzyme and change its shape either activating it, or inactivating it. An allosteric enzyme is made of more than one polypeptide chain. There are two non-competitive sites. One non-competitive site activates the enzyme, ...
... role of allosteric sites. allosteric regulation- regulatory molecules bind on the enzyme and change its shape either activating it, or inactivating it. An allosteric enzyme is made of more than one polypeptide chain. There are two non-competitive sites. One non-competitive site activates the enzyme, ...
Enzymes - OpenStax CNX
... optimal conformation and function for their respective enzymes. Cofactors are inorganic ions such as iron (Fe++) and magnesium (Mg++). One example of an enzyme that requires a metal ion as a cofactor is the enzyme that builds DNA molecules, DNA polymerase, which requires bound zinc ion (Zn++) to fun ...
... optimal conformation and function for their respective enzymes. Cofactors are inorganic ions such as iron (Fe++) and magnesium (Mg++). One example of an enzyme that requires a metal ion as a cofactor is the enzyme that builds DNA molecules, DNA polymerase, which requires bound zinc ion (Zn++) to fun ...
1a Endo Sys I - Superior Glands
... 3. Adenylate cyclase produces cyclic AMP (second messenger) by converting ATP --> cAMP 5. cAMP, in turn, activates phosphorylating activation proteins (protein kinases) that trigger additional intracellular changes (enzyme activation, secretion, ion channel changes) to promote a specific response (A ...
... 3. Adenylate cyclase produces cyclic AMP (second messenger) by converting ATP --> cAMP 5. cAMP, in turn, activates phosphorylating activation proteins (protein kinases) that trigger additional intracellular changes (enzyme activation, secretion, ion channel changes) to promote a specific response (A ...
Physiological adaptations of Saccharomyces cerevisiae evolved for
... Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ...
... Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ...
Recombinant Rat Ciliary Neurotrophic Factor (CNTF)
... Ciliary neurotrophic factor (CNTF) is a polypeptide initially purified from chick embryo ocular tissue and identified as a trophic factor for embryonic chick ciliary parasympathetic neurons in culture. Subsequent studies have demonstrated that CNTF is a survival factor for additional neuronal cell t ...
... Ciliary neurotrophic factor (CNTF) is a polypeptide initially purified from chick embryo ocular tissue and identified as a trophic factor for embryonic chick ciliary parasympathetic neurons in culture. Subsequent studies have demonstrated that CNTF is a survival factor for additional neuronal cell t ...
Recombinant Rat Ciliary Neurotrophic Factor (CNTF)
... Ciliary neurotrophic factor (CNTF) is a polypeptide initially purified from chick embryo ocular tissue and identified as a trophic factor for embryonic chick ciliary parasympathetic neurons in culture. Subsequent studies have demonstrated that CNTF is a survival factor for additional neuronal cell t ...
... Ciliary neurotrophic factor (CNTF) is a polypeptide initially purified from chick embryo ocular tissue and identified as a trophic factor for embryonic chick ciliary parasympathetic neurons in culture. Subsequent studies have demonstrated that CNTF is a survival factor for additional neuronal cell t ...
of Glycolysis
... • Phosphofructokinase‐ major control point; first enzyme “unique” to glycolysis • Pyruvate kinase •Phosphofructokinase responds to changes in: • Energy state of the cell (high ATP levels inhibit) • H+ concentration (high lactate levels inhibit) • Availability of alternate fuels such as fatty acids, ...
... • Phosphofructokinase‐ major control point; first enzyme “unique” to glycolysis • Pyruvate kinase •Phosphofructokinase responds to changes in: • Energy state of the cell (high ATP levels inhibit) • H+ concentration (high lactate levels inhibit) • Availability of alternate fuels such as fatty acids, ...
Autophagosome expansion due to amino acid deprivation
... Specifically, a heterotrimeric Gi3-protein controls autophagic sequestration in HT-29 cells (Ogier-Denis et al., 1995; OgierDenis et al., 1996). It has also been shown that the PI3-kinase inhibitors wortmannin and LY294002 stop autophagy at the sequestration step in rat hepatocytes (Blommaart et al. ...
... Specifically, a heterotrimeric Gi3-protein controls autophagic sequestration in HT-29 cells (Ogier-Denis et al., 1995; OgierDenis et al., 1996). It has also been shown that the PI3-kinase inhibitors wortmannin and LY294002 stop autophagy at the sequestration step in rat hepatocytes (Blommaart et al. ...
Autophosphorylation Activity of the Arabidopsis Ethylene Receptor
... proteins are also involved in more complex signaling pathways, termed phosphorelays. In these pathways the receptors are often hybrid proteins containing a receiver domain at the carboxyl terminus of their kinase domain. After autophosphorylation of the histidine residue in the kinase domain, the ph ...
... proteins are also involved in more complex signaling pathways, termed phosphorelays. In these pathways the receptors are often hybrid proteins containing a receiver domain at the carboxyl terminus of their kinase domain. After autophosphorylation of the histidine residue in the kinase domain, the ph ...
basic biochemistry - Personal Webspace for QMUL
... Glycolysis regulation reflects its dual role in: Degrading glucose to make ATP Providing building blocks for biosynthetic reactions (i.e. formation long-chain fatty acids) NOTE: In metabolic pathways, enzymes catalysing essentially irreversible reactions are potential sites of control/regu ...
... Glycolysis regulation reflects its dual role in: Degrading glucose to make ATP Providing building blocks for biosynthetic reactions (i.e. formation long-chain fatty acids) NOTE: In metabolic pathways, enzymes catalysing essentially irreversible reactions are potential sites of control/regu ...
H 2 O
... The Warburg Effect • In oncology, the Warburg effect is that most cancer cells predominantly produce energy by a high rate of glycolysis followed by lactic acid fermentation in the cytosol, rather than by a comparatively low rate of glycolysis followed by oxidation of pyruvate in mitochondria like ...
... The Warburg Effect • In oncology, the Warburg effect is that most cancer cells predominantly produce energy by a high rate of glycolysis followed by lactic acid fermentation in the cytosol, rather than by a comparatively low rate of glycolysis followed by oxidation of pyruvate in mitochondria like ...
Unit 8A
... models of PD induced with these toxins suggest that mitochondrial dysfunction and oxidative stress are important pathogenic mechanisms. In humans, reduced complex I activity has been reported in both post-mortem brain samples and platelets of sporadic/idiopathic PD cases. - Lewy bodies observed in P ...
... models of PD induced with these toxins suggest that mitochondrial dysfunction and oxidative stress are important pathogenic mechanisms. In humans, reduced complex I activity has been reported in both post-mortem brain samples and platelets of sporadic/idiopathic PD cases. - Lewy bodies observed in P ...