Cardiovascular Effects of Androgens
... translocate to the nucleus where they dimerize and bind to regulatory DNA sequences on target genes and activate transcription (Simental et al., 1992). Several co-regulatory proteins that bind and regulate the activity of receptors have been identified. These include both coactivators that positivel ...
... translocate to the nucleus where they dimerize and bind to regulatory DNA sequences on target genes and activate transcription (Simental et al., 1992). Several co-regulatory proteins that bind and regulate the activity of receptors have been identified. These include both coactivators that positivel ...
PDF
... the cytoplasmic β-catenin-destruction machinery, which contains, among other proteins, glycogen synthase kinase 3β [GSK3β; Shaggy (Sgg) in Drosophila]. Receptors (Fz and LRP5/6) are activated by Wnt signal to disassemble the destruction complex, leading to the stabilization of β-catenin, its translo ...
... the cytoplasmic β-catenin-destruction machinery, which contains, among other proteins, glycogen synthase kinase 3β [GSK3β; Shaggy (Sgg) in Drosophila]. Receptors (Fz and LRP5/6) are activated by Wnt signal to disassemble the destruction complex, leading to the stabilization of β-catenin, its translo ...
Enzymatic features of the glucose metabolism in tumor cells
... The main allosteric regulators of HK-1 and HK-2 are ATP, inorganic phosphate and the reaction product glucose 6-phosphate. Inorganic phosphate antagonizes glucose 6-phosphate inhibition of HK-1 but adds to glucose 6-phosphate inhibition of HK-2. This remarkable difference has led to the suggestion t ...
... The main allosteric regulators of HK-1 and HK-2 are ATP, inorganic phosphate and the reaction product glucose 6-phosphate. Inorganic phosphate antagonizes glucose 6-phosphate inhibition of HK-1 but adds to glucose 6-phosphate inhibition of HK-2. This remarkable difference has led to the suggestion t ...
Cells part 2 - fog.ccsf.edu
... Overview of respiration • Glycolysis: Glucose is split, 2 pyruvates are formed, a little ATP is gained ( 2 ATP/ glucose) • The Citric Acid Cycle: Pyruvates are brokent into CO2, Redox molecules NAD+ and FAD are charged up, a little ATP is gained (2 ATP/ glucose) • Electron transport: Lots of ATP is ...
... Overview of respiration • Glycolysis: Glucose is split, 2 pyruvates are formed, a little ATP is gained ( 2 ATP/ glucose) • The Citric Acid Cycle: Pyruvates are brokent into CO2, Redox molecules NAD+ and FAD are charged up, a little ATP is gained (2 ATP/ glucose) • Electron transport: Lots of ATP is ...
Multimeric Protein Structures of African Horsesickness Virus
... aetiological agent of African horsesickness, a highly infectious non-contagious disease of equines. The AHSV virion is composed of seven structural proteins organised into a double layered capsid, which encloses ten double-stranded RNA segments. The double stranded (ds) RNA genome of AHSV encodes, i ...
... aetiological agent of African horsesickness, a highly infectious non-contagious disease of equines. The AHSV virion is composed of seven structural proteins organised into a double layered capsid, which encloses ten double-stranded RNA segments. The double stranded (ds) RNA genome of AHSV encodes, i ...
Chapter 8 - HCC Learning Web
... This increase in organization does not violate the second law of thermodynamics. The entropy of a particular system, such as an organism, may decrease as long as the total entropy of the universe—the system plus its surroundings—increases. Organisms are islands of low entropy in an increasingl ...
... This increase in organization does not violate the second law of thermodynamics. The entropy of a particular system, such as an organism, may decrease as long as the total entropy of the universe—the system plus its surroundings—increases. Organisms are islands of low entropy in an increasingl ...
INTRODUCTION - international journal of advances in
... performance, and also plays an important role in the myocardial and vascular remodeling processes. Radical oxygen species induced cardiac apoptosis which is mediated through signaling systems, like intracellular Ca2 +, cytokines, lipid oxidation, and proto-oncogene activation. The perturbation of in ...
... performance, and also plays an important role in the myocardial and vascular remodeling processes. Radical oxygen species induced cardiac apoptosis which is mediated through signaling systems, like intracellular Ca2 +, cytokines, lipid oxidation, and proto-oncogene activation. The perturbation of in ...
Chapter 9 - Slothnet
... Negative and positive feedback A high concentration of a metabolic product inhibits action of an enzyme in the pathway. Excess product of one pathway can activate an enzyme in another ...
... Negative and positive feedback A high concentration of a metabolic product inhibits action of an enzyme in the pathway. Excess product of one pathway can activate an enzyme in another ...
Lipidomics in Cell Regulation
... Ensure a stable cellular environment Provides a 2-D space for efficient chemical reaction The lipids creates an optimal environment for protein function in the membrane More than 300 lipid species are found in the plasma membrane ...
... Ensure a stable cellular environment Provides a 2-D space for efficient chemical reaction The lipids creates an optimal environment for protein function in the membrane More than 300 lipid species are found in the plasma membrane ...
Master proper.docx - BORA
... either Natural Killer (NK) cells or lymphoblasts that become either T or B lymphocytes3. ...
... either Natural Killer (NK) cells or lymphoblasts that become either T or B lymphocytes3. ...
ATPase - cloudfront.net
... of life; the most commonly used "energy source" of cells for most organisms. It is present in the cytoplasm and nucleoplasm of every All physiological mechanisms that require energy for operation obtain it directly from stored ATP ...
... of life; the most commonly used "energy source" of cells for most organisms. It is present in the cytoplasm and nucleoplasm of every All physiological mechanisms that require energy for operation obtain it directly from stored ATP ...
Midterm #2 - UC Davis Plant Sciences
... d) Assume that the PMF of the mitochondria (calculated above) is not coupled to the synthesis of ATP but is coupled to the uptake of pyruvate from the cytosol into the mitochondria (one proton and one molecule of pyruvate are co-transported into the mitochondria). Calculate the gradient of pyruvate ...
... d) Assume that the PMF of the mitochondria (calculated above) is not coupled to the synthesis of ATP but is coupled to the uptake of pyruvate from the cytosol into the mitochondria (one proton and one molecule of pyruvate are co-transported into the mitochondria). Calculate the gradient of pyruvate ...
Lecture-Oxidative Phsphorylation
... Process in which ATP is formed as a result of the transfer of electrons from NADH or FADH2 to O2 via a series of electron carriers ...
... Process in which ATP is formed as a result of the transfer of electrons from NADH or FADH2 to O2 via a series of electron carriers ...
Cell - Notes Milenge
... organelle’s purported responsiveness to changes in intracellular Ca2+ flux.[24] But the presence of the MAM resolves this apparent contradiction: the close physical association between the two organelles results in Ca2+ microdomains at contact points that facilitate efficient Ca2+ transmission from ...
... organelle’s purported responsiveness to changes in intracellular Ca2+ flux.[24] But the presence of the MAM resolves this apparent contradiction: the close physical association between the two organelles results in Ca2+ microdomains at contact points that facilitate efficient Ca2+ transmission from ...
INTRODUCTION
... fragmentation of the mitochondrial reticulum there is one nucleoid per minimal sized fragment. The crystal structure of TFAM shows that it bends mtDNA in a sharp U-turn. Several other proteins are a part, often transiently, of the nucleoid including prohibitin, single-stranded DNA-binding protein, m ...
... fragmentation of the mitochondrial reticulum there is one nucleoid per minimal sized fragment. The crystal structure of TFAM shows that it bends mtDNA in a sharp U-turn. Several other proteins are a part, often transiently, of the nucleoid including prohibitin, single-stranded DNA-binding protein, m ...
Metabolic Fate of Glucose Metabolic Fate of Fatty Acids
... fuel. It prefers fatty acids and α-keto acids as a source of energy for its activities. • After absorption by the intestine, dietary fuel’s first destination is the liver. The liver is able to gauge fuel availability and adjust its metabolism to regulate the level of various metabolites in the blood ...
... fuel. It prefers fatty acids and α-keto acids as a source of energy for its activities. • After absorption by the intestine, dietary fuel’s first destination is the liver. The liver is able to gauge fuel availability and adjust its metabolism to regulate the level of various metabolites in the blood ...
Characterizing the Secreted Proteome of Mycobacterium
... improper sample mixing and cell lysis. Because iTRAQ Reagent labels all peptides, normalizing the three samples using a nonsecreted protein corrects for both quantification due to lysis and mixing, enabling true changes in secretion to be accurately measured. In this case, the chaperones, GroEL, Dna ...
... improper sample mixing and cell lysis. Because iTRAQ Reagent labels all peptides, normalizing the three samples using a nonsecreted protein corrects for both quantification due to lysis and mixing, enabling true changes in secretion to be accurately measured. In this case, the chaperones, GroEL, Dna ...
Study of the role of estrogen receptor variant, ER36, in non genomic
... best with his wife and kid, and many other kids to come. I wish to thank Lucie Malbeteau for always being present to ease out our stress, don’t worry the cells will grow and I’m confident you will do a great thesis. I wish to thank Hanine Lattouf, our other Lebanese student, for all the fun times we ...
... best with his wife and kid, and many other kids to come. I wish to thank Lucie Malbeteau for always being present to ease out our stress, don’t worry the cells will grow and I’m confident you will do a great thesis. I wish to thank Hanine Lattouf, our other Lebanese student, for all the fun times we ...
Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for anti-viral therapy.
... large changes in metabolite concentrations first appear18. A battery of five assays was used: (i) direct measurement of key cellular metabolic influxes (glucose and glutamine) and effluxes (pyruvate, lactate, alanine and glutamate), (ii) kinetic flux profiling with uniformly 13C-labeled glucose, (ii ...
... large changes in metabolite concentrations first appear18. A battery of five assays was used: (i) direct measurement of key cellular metabolic influxes (glucose and glutamine) and effluxes (pyruvate, lactate, alanine and glutamate), (ii) kinetic flux profiling with uniformly 13C-labeled glucose, (ii ...
DOPAMINE RECEPTORS
... putative membrane spanning-helices linked by intracellular and extracellular protein loops (Figure 1). One or more potential sites for glycosylation are found on the amino terminus and second extracellular ...
... putative membrane spanning-helices linked by intracellular and extracellular protein loops (Figure 1). One or more potential sites for glycosylation are found on the amino terminus and second extracellular ...
Comparison of good-and bad-quality cork: application of high
... Cork is one of the most valuable non-wood forest products and plays an important role in Mediterranean economies. The production of high-quality cork is dependent on both genome and environment, posing constraints on the industry because an ever-growing amount of bad-quality cork (BQC) development h ...
... Cork is one of the most valuable non-wood forest products and plays an important role in Mediterranean economies. The production of high-quality cork is dependent on both genome and environment, posing constraints on the industry because an ever-growing amount of bad-quality cork (BQC) development h ...
Recognition Specificity for the Bacterial Avirulence Protein AvrPto Is
... will be required to test this possibility because tobacco ...
... will be required to test this possibility because tobacco ...
Hooked on fat: the role of lipid synthesis in cancer metabolism and
... tissue, which has a high rate of FA biosynthesis. Although Medes and colleagues noted that tumour tissue also takes up lipids from the tissue environment, they concluded that de novo lipogenesis provides the majority of lipids required for the rapid proliferation of cancer cells (Medes et al., 1953) ...
... tissue, which has a high rate of FA biosynthesis. Although Medes and colleagues noted that tumour tissue also takes up lipids from the tissue environment, they concluded that de novo lipogenesis provides the majority of lipids required for the rapid proliferation of cancer cells (Medes et al., 1953) ...