Comparison of good-and bad-quality cork: application of high
... Cork is one of the most valuable non-wood forest products and plays an important role in Mediterranean economies. The production of high-quality cork is dependent on both genome and environment, posing constraints on the industry because an ever-growing amount of bad-quality cork (BQC) development h ...
... Cork is one of the most valuable non-wood forest products and plays an important role in Mediterranean economies. The production of high-quality cork is dependent on both genome and environment, posing constraints on the industry because an ever-growing amount of bad-quality cork (BQC) development h ...
Crystallization and X-Ray Crystallographic Studies of Wild
... 1988; Shortle et al., 1990). Residues 28 and 173 of the αsubunit interact with the carboxyl-terminal folding domain, and when they are substituted the rate of folding of the enzyme and the stabilities of folding intermediates change (Jeong, 2003). Pro28 may contribute to the formation of a folding n ...
... 1988; Shortle et al., 1990). Residues 28 and 173 of the αsubunit interact with the carboxyl-terminal folding domain, and when they are substituted the rate of folding of the enzyme and the stabilities of folding intermediates change (Jeong, 2003). Pro28 may contribute to the formation of a folding n ...
Detailed Supporting Information
... uptake flux. For each maximum capacity we computed the fluxes that maximize the biomass production rate, obtaining a prediction for the optimal flux of all reactions and the optimal biomass production rate. Because the biomass production rate equals the growth rate, using these predictions we can an ...
... uptake flux. For each maximum capacity we computed the fluxes that maximize the biomass production rate, obtaining a prediction for the optimal flux of all reactions and the optimal biomass production rate. Because the biomass production rate equals the growth rate, using these predictions we can an ...
Invited Chapter One
... Of the three subfamilies that include only nematode proteins two contain a single sequence and the third contains three proteins. Even though they signal for a DPP/BMP subfamily member and they are clearly R-Smads, SMA-2 and SMA-3 are different enough from other R-Smads (and each other) that they ea ...
... Of the three subfamilies that include only nematode proteins two contain a single sequence and the third contains three proteins. Even though they signal for a DPP/BMP subfamily member and they are clearly R-Smads, SMA-2 and SMA-3 are different enough from other R-Smads (and each other) that they ea ...
PKCa and PKCe differentially regulate Legionella pneumophila-induced GM-CSF
... spp. [20], and Pneumocystis jiroveci [21]. Furthermore, AMs from GM-CSF -/- mice were defective for Escherichia coli phagocytosis [18] as well as in the production of tumour necrosis factor (TNF)-a [22] and IFN-c [23]. The expression of GM-CSF is controlled by a tight regulatory network involving th ...
... spp. [20], and Pneumocystis jiroveci [21]. Furthermore, AMs from GM-CSF -/- mice were defective for Escherichia coli phagocytosis [18] as well as in the production of tumour necrosis factor (TNF)-a [22] and IFN-c [23]. The expression of GM-CSF is controlled by a tight regulatory network involving th ...
Chapter 20 Carbohydrate Biosynthesis in Plants and Bacteria
... reacts RuBP with O2, which is much more abundant than the proper substrate, CO2. This results in the production of phosphoglycolate which must be processed by photorespiration. 18. Photorespiration and the C4 and CAM pathways Describe the oxygenase activity of ribulose 1,5-bisphosphate carboxylase/o ...
... reacts RuBP with O2, which is much more abundant than the proper substrate, CO2. This results in the production of phosphoglycolate which must be processed by photorespiration. 18. Photorespiration and the C4 and CAM pathways Describe the oxygenase activity of ribulose 1,5-bisphosphate carboxylase/o ...
Cell-to-cell communication Transduction pathways
... •usually not bound to carrier protein •do not readily diffuse across membrane •bind to membrane receptor •H-R complex triggers production of 2nd messenger cAMP, cGMP (cyclic nucleotide monophosphates) IP3 (inositol phospholipids) Ca2+ ions •rapid, short-lived responses; usually metabolic ...
... •usually not bound to carrier protein •do not readily diffuse across membrane •bind to membrane receptor •H-R complex triggers production of 2nd messenger cAMP, cGMP (cyclic nucleotide monophosphates) IP3 (inositol phospholipids) Ca2+ ions •rapid, short-lived responses; usually metabolic ...
Ontologies for biological annotation
... process The processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs ...
... process The processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs ...
University of Groningen Plasticity of airway smooth muscle
... mass as they can be mitogenic for cultured ASM cells and/or can augment growth factor induced proliferation [9]. For example, cholinergic signalling (as described in Chapter 7) [10], tachykinins [11], inflammatory mediators such as histamine [12] and leukotriene D4 [13] have been reported to be pro- ...
... mass as they can be mitogenic for cultured ASM cells and/or can augment growth factor induced proliferation [9]. For example, cholinergic signalling (as described in Chapter 7) [10], tachykinins [11], inflammatory mediators such as histamine [12] and leukotriene D4 [13] have been reported to be pro- ...
Figure Legends - Institute of Cancer Research
... impermeable to large PGN fragments 7. How PRRs integrate information from MAMPs with different “threat content” into a coherent immune response remains, however, an unresolved issue. Binding of PGN and TCT to peptidoglycan recognition receptors stimulates the Drosophila IMD pathway, culminating in a ...
... impermeable to large PGN fragments 7. How PRRs integrate information from MAMPs with different “threat content” into a coherent immune response remains, however, an unresolved issue. Binding of PGN and TCT to peptidoglycan recognition receptors stimulates the Drosophila IMD pathway, culminating in a ...
HYPOXIA AND THE METABOLIC PHENOTYPE OF PROSTATE CANCER CELLS
... xenograft models). Lastly, we will explore the relationship between the sterol regulatory element binding protein (SREBP) pathway and low oxygen, to determine if it is directly influenced by low oxygen in prostate cancer cells. The goal is to determine the relationships between hypoxia, mitochondria ...
... xenograft models). Lastly, we will explore the relationship between the sterol regulatory element binding protein (SREBP) pathway and low oxygen, to determine if it is directly influenced by low oxygen in prostate cancer cells. The goal is to determine the relationships between hypoxia, mitochondria ...
Membrane Protein Expression in Cell
... Cell-free expression has emerged as a promising tool for the fast and efficient production of membrane proteins. The rapidly growing number of successfully produced targets in combination with the continuous development of new applications significantly promotes the distribution of this technology. ...
... Cell-free expression has emerged as a promising tool for the fast and efficient production of membrane proteins. The rapidly growing number of successfully produced targets in combination with the continuous development of new applications significantly promotes the distribution of this technology. ...
The Crystal Structure of Arabidopsis thaliana Allene Oxide Cyclase
... In complete agreement with our biochemical data, we found AOC2 to form trimers when crystallized (Figure 4). The barrel axes of the monomers are tilted ;308 with respect to the trimer axis and pack closely with their barrel walls. Trimerization buries ;2000 A2 of the barrel surface and is the only i ...
... In complete agreement with our biochemical data, we found AOC2 to form trimers when crystallized (Figure 4). The barrel axes of the monomers are tilted ;308 with respect to the trimer axis and pack closely with their barrel walls. Trimerization buries ;2000 A2 of the barrel surface and is the only i ...
AP Biology Chapter Objectives – Campbell 7th Edition Modified from
... 14. Explain how enzyme structure determines enzyme specificity. 15. Explain the induced-fit model of enzyme function. 16. Describe the mechanisms by which enzymes lower activation energy. 17. Explain how substrate concentration affects the rate of an enzyme-catalyzed reaction. 18. Explain how temper ...
... 14. Explain how enzyme structure determines enzyme specificity. 15. Explain the induced-fit model of enzyme function. 16. Describe the mechanisms by which enzymes lower activation energy. 17. Explain how substrate concentration affects the rate of an enzyme-catalyzed reaction. 18. Explain how temper ...
3. Structure Activity Relationships 1. Introduction Acknowledgements
... The molecular initiating event (MIE) can be thought of as a gateway to the AOP. In the purest sense an MIE is a chemical interaction leading to a downstream outcome pathway [2]. Some examples of MIEs would be a compound binding to a protein, or inhibiting an enzyme. Chemistry is key to understanding ...
... The molecular initiating event (MIE) can be thought of as a gateway to the AOP. In the purest sense an MIE is a chemical interaction leading to a downstream outcome pathway [2]. Some examples of MIEs would be a compound binding to a protein, or inhibiting an enzyme. Chemistry is key to understanding ...
Inhibition of breast and brain cancer cell growth by BCCIPa
... domains, several models have been proposed for the role of BRCA2 in tumor suppression. An N-terminus conserved domain in exon 3 (amino acids 48 ± 105) has been implicated in transcriptional regulation of gene expression (Milner et al., 1997; Nordling et al., 1998). Deletion of this region has been i ...
... domains, several models have been proposed for the role of BRCA2 in tumor suppression. An N-terminus conserved domain in exon 3 (amino acids 48 ± 105) has been implicated in transcriptional regulation of gene expression (Milner et al., 1997; Nordling et al., 1998). Deletion of this region has been i ...
Isolation and Characterization of a Cytochrome P450 Gene from
... deduced amino acid sequence of MaP450 has several conserved regions of the cytochrome P450 proteins, but shows only 34-37% identities with those of previously reported F3’5’H genes. Southern blot analysis showed that there are 5-6 copies of MaP450 in the genome of M. armeniacum ‘Blue Pearl’. High-pe ...
... deduced amino acid sequence of MaP450 has several conserved regions of the cytochrome P450 proteins, but shows only 34-37% identities with those of previously reported F3’5’H genes. Southern blot analysis showed that there are 5-6 copies of MaP450 in the genome of M. armeniacum ‘Blue Pearl’. High-pe ...
Structural Insights into Triglyceride Storage Mediated by
... evolutionarily conserved proteins localized to the endoplasmic reticulum that are involved in triglyceride lipid droplet formation. FIT proteins have been shown to mediate the partitioning of cellular triglyceride into lipid droplets, but not triglyceride biosynthesis. FIT proteins do not share prim ...
... evolutionarily conserved proteins localized to the endoplasmic reticulum that are involved in triglyceride lipid droplet formation. FIT proteins have been shown to mediate the partitioning of cellular triglyceride into lipid droplets, but not triglyceride biosynthesis. FIT proteins do not share prim ...
Protein Metabolism and Acidosis
... Protein degradation and synthesis is a continuous process that functions to eliminate abnormal proteins and to permit the regulation of cellular metabolism. The rate at which protein degradation occurs varies with both the nutritional and hormonal state of cells. One of the key determinants of prote ...
... Protein degradation and synthesis is a continuous process that functions to eliminate abnormal proteins and to permit the regulation of cellular metabolism. The rate at which protein degradation occurs varies with both the nutritional and hormonal state of cells. One of the key determinants of prote ...
Lecture 12-14 (Parker) - Department of Chemistry ::: CALTECH
... The activities of PFK2 and FBP2 are reciprocally controlled by the phosphorylation of a single serine residue At low glucose levels a rise in the hormone glucagon triggers a cAMP signaling cascade leading to the phosphorylation of the bifunctional enzyme by protein kinase A. This modification activ ...
... The activities of PFK2 and FBP2 are reciprocally controlled by the phosphorylation of a single serine residue At low glucose levels a rise in the hormone glucagon triggers a cAMP signaling cascade leading to the phosphorylation of the bifunctional enzyme by protein kinase A. This modification activ ...
insulin resistance
... insulin-receptor events •The insulin receptor is a tyrosine kinase. = an enzyme that transfers phosphate groups from ATP to tyrosine residues on intracellular target proteins. •Binding of insulin to receptor causes autophosphorylation, which activates the catalytic activity of the receptor •The act ...
... insulin-receptor events •The insulin receptor is a tyrosine kinase. = an enzyme that transfers phosphate groups from ATP to tyrosine residues on intracellular target proteins. •Binding of insulin to receptor causes autophosphorylation, which activates the catalytic activity of the receptor •The act ...
