Biological ontologies for human functional annotation and
... Annotation of Biological Entities We have shown that interleukin-1 (IL-1)
and IL-2
...
... Annotation of Biological Entities We have shown that
The Puzzle of the Krebs Citric Acid Cycle: Assembling the Pieces of
... possibility mentioned; then many different keto compounds could participate in this addition reaction. This problem arises again in searching the next sequence of reactions, since the conversion of the first product back into the feeder will not always be chemically possibly under a reasonable set o ...
... possibility mentioned; then many different keto compounds could participate in this addition reaction. This problem arises again in searching the next sequence of reactions, since the conversion of the first product back into the feeder will not always be chemically possibly under a reasonable set o ...
Chapter 6 Pichia pastoris
... (Saccharomyces cerevisiae and Pichia pastoris), mammalian cells, amphibian oocytes (Xenopus laevis), insect cells and bacteria (Escherichia coli). Plant cells are useful as hosts if mutants are available (Holton et al., 1993), but in many cases the distinction from resident activities may present a ...
... (Saccharomyces cerevisiae and Pichia pastoris), mammalian cells, amphibian oocytes (Xenopus laevis), insect cells and bacteria (Escherichia coli). Plant cells are useful as hosts if mutants are available (Holton et al., 1993), but in many cases the distinction from resident activities may present a ...
Биохимия жидкостей полости рта
... resorption (breakdown) of bone tissue and division odontoblasts. • Nerve growth factor (NGF) – has a powerful anti-inflammatory effect. • Parotin - promotes mineralization. • Renin - vasoconstrictor activity. • Biologically active substances of saliva have endocrine function and are involved in the ...
... resorption (breakdown) of bone tissue and division odontoblasts. • Nerve growth factor (NGF) – has a powerful anti-inflammatory effect. • Parotin - promotes mineralization. • Renin - vasoconstrictor activity. • Biologically active substances of saliva have endocrine function and are involved in the ...
Interaction interfaces of protein domains are not topologically
... that the interacting proteins in Saccharomyces cerevisiae, when compared with their orthologues from Caenorhabditis elegans, evolve at similar rates. Recent studies, however, have shown that the interacting proteins in closely related genomes have a slight influence on the rate at which these protein ...
... that the interacting proteins in Saccharomyces cerevisiae, when compared with their orthologues from Caenorhabditis elegans, evolve at similar rates. Recent studies, however, have shown that the interacting proteins in closely related genomes have a slight influence on the rate at which these protein ...
DOC
... Both studies confirm that the methodology, previously used to measure protein synthesis in a wide variety of mammals, fish (reviewed by Houlihan et al., [9] and amphibians [10] can be successfully applied to measure protein synthesis in crustaceans. Protein synthesis rates have been measured using t ...
... Both studies confirm that the methodology, previously used to measure protein synthesis in a wide variety of mammals, fish (reviewed by Houlihan et al., [9] and amphibians [10] can be successfully applied to measure protein synthesis in crustaceans. Protein synthesis rates have been measured using t ...
EF-TU - Soran University
... to the cell cycle or in response to cellular stresses such as starvation or accumulation of unfolded proteins in the endoplasmic reticulum. Mechanisms include regulation by signal-activated phosphorylation or dephosphorylation of initiation and elongation factors. www.soran.edu.iq ...
... to the cell cycle or in response to cellular stresses such as starvation or accumulation of unfolded proteins in the endoplasmic reticulum. Mechanisms include regulation by signal-activated phosphorylation or dephosphorylation of initiation and elongation factors. www.soran.edu.iq ...
The Phosphoproteome of a Chlamydomonas reinhardtii Eyespot
... identification of 202 proteins that were covered by at least two peptides in the mass spectrometry (MS) analysis (Schmidt et al., 2006). Besides the already abovementioned proteins, this analysis revealed the presence of proteins from diverse functional groups in the eyespot. These include, for exam ...
... identification of 202 proteins that were covered by at least two peptides in the mass spectrometry (MS) analysis (Schmidt et al., 2006). Besides the already abovementioned proteins, this analysis revealed the presence of proteins from diverse functional groups in the eyespot. These include, for exam ...
Self-Interaction of the Herpes Simplex Virus Type 1
... zinc-finger-like region as directly involved in the self-interaction. Furthermore mutants with lesions in this region were not found to be trans-dominant (Smith et al., 1991), which supports the notion that the zinc-finger-like region may be required for multimerization. RESULTS An ICP27 NLS mutant ...
... zinc-finger-like region as directly involved in the self-interaction. Furthermore mutants with lesions in this region were not found to be trans-dominant (Smith et al., 1991), which supports the notion that the zinc-finger-like region may be required for multimerization. RESULTS An ICP27 NLS mutant ...
INTRODUCTION - international journal of advances in
... performance, and also plays an important role in the myocardial and vascular remodeling processes. Radical oxygen species induced cardiac apoptosis which is mediated through signaling systems, like intracellular Ca2 +, cytokines, lipid oxidation, and proto-oncogene activation. The perturbation of in ...
... performance, and also plays an important role in the myocardial and vascular remodeling processes. Radical oxygen species induced cardiac apoptosis which is mediated through signaling systems, like intracellular Ca2 +, cytokines, lipid oxidation, and proto-oncogene activation. The perturbation of in ...
Chapter 17 Lecture PowerPoint - McGraw Hill Higher Education
... mRNA secondary structure to control translation initiation • Riboswitches can be used to control translation initiation via mRNA 2° structure – 5’-untranslated region of E. coli thiM mRNA contain a riboswitch – This includes an aptamer that binds thiamine and its metabolite ...
... mRNA secondary structure to control translation initiation • Riboswitches can be used to control translation initiation via mRNA 2° structure – 5’-untranslated region of E. coli thiM mRNA contain a riboswitch – This includes an aptamer that binds thiamine and its metabolite ...
nature of polyethyleneimine-glucose oxidase interactions
... low strength (Figures 8, right). In addition, the formed bonds tend to disappear and re-appear during MD simulation (Figures 8, right). In the interior of enzyme, at LIG1, there are two kinds of HB, formed between the enzyme and ligand: “amino acid (O) ... (H) ligand” and “amino acid (H) ... (N) lig ...
... low strength (Figures 8, right). In addition, the formed bonds tend to disappear and re-appear during MD simulation (Figures 8, right). In the interior of enzyme, at LIG1, there are two kinds of HB, formed between the enzyme and ligand: “amino acid (O) ... (H) ligand” and “amino acid (H) ... (N) lig ...
Norton J Nutr 2006
... mTOR are mediated through TSC2. AMPK directly phosphorylates TSC2, increasing formation of the TSC1/TSC2 complex and inhibiting Rheb. Because AMPK is activated by exercise and a decreased ATP/AMP ratio, AMPK activation and its effects on the mTOR pathway appear to be a primary mechanism reducing pro ...
... mTOR are mediated through TSC2. AMPK directly phosphorylates TSC2, increasing formation of the TSC1/TSC2 complex and inhibiting Rheb. Because AMPK is activated by exercise and a decreased ATP/AMP ratio, AMPK activation and its effects on the mTOR pathway appear to be a primary mechanism reducing pro ...
Branched-Chain Amino Acids in Exercise
... sclerosis complex (TSC1 and TSC2), Rheb, and AMP kinase (AMPK) (27–29) (Fig. 3). TSC1/TSC2 and Rheb are crucial regulators situated between protein kinase B (PKB) and mTOR. Rheb, a Ras-like GTPase, is a positive regulator of mTOR in vivo. The action of Rheb is opposed by the TSC1/TSC2 complex, which ...
... sclerosis complex (TSC1 and TSC2), Rheb, and AMP kinase (AMPK) (27–29) (Fig. 3). TSC1/TSC2 and Rheb are crucial regulators situated between protein kinase B (PKB) and mTOR. Rheb, a Ras-like GTPase, is a positive regulator of mTOR in vivo. The action of Rheb is opposed by the TSC1/TSC2 complex, which ...
Silk-inspired polymers and proteins
... stimuli, triggering protein assembly into fibres in a precisely controlled manner [28]. In vitro, self-assembly of silkinspired polymers/proteins owing to the formation of β-sheets is typically induced by exposure to a solvent such as an aqueous solution of potassium phosphate known to salt out the ...
... stimuli, triggering protein assembly into fibres in a precisely controlled manner [28]. In vitro, self-assembly of silkinspired polymers/proteins owing to the formation of β-sheets is typically induced by exposure to a solvent such as an aqueous solution of potassium phosphate known to salt out the ...
Monocyte chemoattrac- tant protein
... lpr mice has been reported to be upregulated (10, 11), and MCP-1 may also be responsible for inflammation in nephritis (12). In addition, the fact that MCP-1 deficiency resulted in the improvement of glomerulonephritis in MRL lpr mice (13) and that treatment with a MCP-1 antagonist results in reduct ...
... lpr mice has been reported to be upregulated (10, 11), and MCP-1 may also be responsible for inflammation in nephritis (12). In addition, the fact that MCP-1 deficiency resulted in the improvement of glomerulonephritis in MRL lpr mice (13) and that treatment with a MCP-1 antagonist results in reduct ...
Best Plant Protein
... increase total protein intake or timely deliver protein as needed. Proper use of highly rated protein sources (digestibility and amino acid content) can deliver the exercise-induced higher protein requirements for athletic training while minimizing calories to achieve body composition goals. BPP com ...
... increase total protein intake or timely deliver protein as needed. Proper use of highly rated protein sources (digestibility and amino acid content) can deliver the exercise-induced higher protein requirements for athletic training while minimizing calories to achieve body composition goals. BPP com ...
APC2 Antibody
... APC2 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC2 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase ...
... APC2 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC2 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase ...
PDF
... al., 2005; Pera et al., 2003; Sato and Sargent, 1989). However, it is not known how the activity of FGF is regulated in the embryo to account for its role during neural induction. As it is well established that several proteoglycans (PGs) can regulate the activity of FGF, in some cases working as co ...
... al., 2005; Pera et al., 2003; Sato and Sargent, 1989). However, it is not known how the activity of FGF is regulated in the embryo to account for its role during neural induction. As it is well established that several proteoglycans (PGs) can regulate the activity of FGF, in some cases working as co ...
Slide 1
... – Balance of amino acids in a diet is as important as the amounts of individual amino acids • Amino acids can only be used to the extent of the least abundant amino acid relative to the animal’s requirement – Remainder of amino acids will be deaminated and N will be excreted as: » Urea in mammals » ...
... – Balance of amino acids in a diet is as important as the amounts of individual amino acids • Amino acids can only be used to the extent of the least abundant amino acid relative to the animal’s requirement – Remainder of amino acids will be deaminated and N will be excreted as: » Urea in mammals » ...
Cytokinin Lecture
... 3. A DNA breakdown product that causes shoot cell division (in the presence of auxin). ...
... 3. A DNA breakdown product that causes shoot cell division (in the presence of auxin). ...
Enzymes - University of Lethbridge
... Discovery based approach to identify the set of transcripts or protein in a cell under a particular condition. Comparisons of the transcriptome (or proteome) in the presence and absence of a substrate can be used to identify the enzymes within a pathway, the likely products and some indication of th ...
... Discovery based approach to identify the set of transcripts or protein in a cell under a particular condition. Comparisons of the transcriptome (or proteome) in the presence and absence of a substrate can be used to identify the enzymes within a pathway, the likely products and some indication of th ...
Protein kinases of the human malaria parasite Plasmodium
... placed into the OPK ("other protein kinases") group. The primary structure of all enzymes in these groups conform to the model described by Hanks, in which the catalytic domain is subdivided into eleven subdomains, which can be aligned across all groups. In addition to the "typical" ePKs, several en ...
... placed into the OPK ("other protein kinases") group. The primary structure of all enzymes in these groups conform to the model described by Hanks, in which the catalytic domain is subdivided into eleven subdomains, which can be aligned across all groups. In addition to the "typical" ePKs, several en ...
what we`re reading
... eight Gainer – Looking to bulk up? Weight gainer combines protein, often whey, with a mix of high-carbohydrate ingredients that makes it much more calorie-dense than typical protein powders. It is often used by bodybuilders who are looking to pack on the pounds, or by serious athletes who have dif ...
... eight Gainer – Looking to bulk up? Weight gainer combines protein, often whey, with a mix of high-carbohydrate ingredients that makes it much more calorie-dense than typical protein powders. It is often used by bodybuilders who are looking to pack on the pounds, or by serious athletes who have dif ...
Paracrine signalling
Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.