
The lysosome as a command-and-control center for cellular
... “top-down” manner, as they involve the engagement of a growth factor ligand to its receptor on the cell surface, followed by signal propagation inside the cell (Taniguchi et al., 2006). Growth factor–derived signals trigger changes in the rate of biochemical reactions occurring in the cytoplasm and ...
... “top-down” manner, as they involve the engagement of a growth factor ligand to its receptor on the cell surface, followed by signal propagation inside the cell (Taniguchi et al., 2006). Growth factor–derived signals trigger changes in the rate of biochemical reactions occurring in the cytoplasm and ...
Chapter 12 Synapses and Neurotransmitters
... This is the ability of your neurons to process information, store the information and recall the information, and make decisions – synaptic delay slows the transmission of nerve signals – more synapses in a neural pathway, the longer it takes for information to get from its origin to its destination ...
... This is the ability of your neurons to process information, store the information and recall the information, and make decisions – synaptic delay slows the transmission of nerve signals – more synapses in a neural pathway, the longer it takes for information to get from its origin to its destination ...
Type 2 Diabetes
... On carbohydrate metabolism.. Reduces rate of release of glucose from the liver by ...
... On carbohydrate metabolism.. Reduces rate of release of glucose from the liver by ...
Roles of Plant Hormones and Their Interplay in Rice Immunity
... blast infection and abiotic stresses (Yang et al., 2004), suggesting that SA plays a role in rice immunity against pathogen infection, although it was known that the compromised resistance in Arabidopsis NahG plants might be caused by the by-product (catechol) of the NahG activity (Van Wees and Gla ...
... blast infection and abiotic stresses (Yang et al., 2004), suggesting that SA plays a role in rice immunity against pathogen infection, although it was known that the compromised resistance in Arabidopsis NahG plants might be caused by the by-product (catechol) of the NahG activity (Van Wees and Gla ...
An Expression and Bioinformatics Analysis of the Arabidopsis
... carboxypeptidases. Based on their sequences, these serine carboxypeptidase-like (SCPL) proteins can be divided into several major clades. The first group consists of 21 proteins which, despite the function implied by their annotation, includes two that have been shown to function as acyltransferases ...
... carboxypeptidases. Based on their sequences, these serine carboxypeptidase-like (SCPL) proteins can be divided into several major clades. The first group consists of 21 proteins which, despite the function implied by their annotation, includes two that have been shown to function as acyltransferases ...
Cloning and characterization of the
... the four known yeast tRNA Ψ synthases (Pus1p–Pus4p) is essential for viability, at least under normal growth conditions. However, genetic experiments have implicated scPus1p in the nuclear export of tRNA. PUS1 was originally identified by its ability to complement a mutation that was synthetically l ...
... the four known yeast tRNA Ψ synthases (Pus1p–Pus4p) is essential for viability, at least under normal growth conditions. However, genetic experiments have implicated scPus1p in the nuclear export of tRNA. PUS1 was originally identified by its ability to complement a mutation that was synthetically l ...
Sequence-Specific Deoxyribonucleic Acid (DNA) Recognition by
... is that many genes appear to be regulated in collaboration with proximally bound, structurally diverse transcription factors including cAMP response element binding protein (CREB), CCAAT-enhancer binding protein (C/EBP-!), pituitary homeobox (Pitx), GATA-4, early growth response protein 1 (EGR-1), ! ...
... is that many genes appear to be regulated in collaboration with proximally bound, structurally diverse transcription factors including cAMP response element binding protein (CREB), CCAAT-enhancer binding protein (C/EBP-!), pituitary homeobox (Pitx), GATA-4, early growth response protein 1 (EGR-1), ! ...
國立清華大學 - 罕見疾病基金會
... metabolism in eukaryotic cells. This organelle is formed by two phospholipid membranes, outer- and inner-membrane, to separate three compartments which from outside to inside are called cytosol, inter-membrane space and matrix. There are many protein complexes on the inner-membrane which participate ...
... metabolism in eukaryotic cells. This organelle is formed by two phospholipid membranes, outer- and inner-membrane, to separate three compartments which from outside to inside are called cytosol, inter-membrane space and matrix. There are many protein complexes on the inner-membrane which participate ...
Orphan nuclear receptors: therapeutic opportunities in skeletal muscle
... Excess triglyceride in insulin resistant muscle has been shown to alter insulin signaling via consequent increases in lipid intermediates, such as fatty-acyl CoA, diacylglycerol, and ceramides. Activation of protein kinase C by diacylglycerol inhibits the tyrosine kinase activity of the insulin rece ...
... Excess triglyceride in insulin resistant muscle has been shown to alter insulin signaling via consequent increases in lipid intermediates, such as fatty-acyl CoA, diacylglycerol, and ceramides. Activation of protein kinase C by diacylglycerol inhibits the tyrosine kinase activity of the insulin rece ...
calcium, kinases and nodulation signalling in legumes
... inducing spiking26 (see below). These observations suggest that Ca2+ spiking and the Ca2+ flux are independent to some extent and might be involved in activating different (but possibly overlapping) responses. Assigning functions to Nod-factor-induced cellular responses is still a significant challe ...
... inducing spiking26 (see below). These observations suggest that Ca2+ spiking and the Ca2+ flux are independent to some extent and might be involved in activating different (but possibly overlapping) responses. Assigning functions to Nod-factor-induced cellular responses is still a significant challe ...
H - IS MU
... Some cells require many NADPH. Its production in oxidative phase is associated with formation of large amount of pentoses, that the cell does not need. The pentoses are converted to fructose-6-phosphate and glyceraldehyde-3-P that are inermediates of glycolysis. ...
... Some cells require many NADPH. Its production in oxidative phase is associated with formation of large amount of pentoses, that the cell does not need. The pentoses are converted to fructose-6-phosphate and glyceraldehyde-3-P that are inermediates of glycolysis. ...
Cell biology of carbohydrate metabolism
... 16 h. Twenty-four h later, cells were harvested, and luciferase activity was measured. Data are expressed as the -fold induction by comparing the relative luciferase activity from high glucose samples divided by low glucose samples. Values represent means ± S.D. of triplicate samples. B, functional ...
... 16 h. Twenty-four h later, cells were harvested, and luciferase activity was measured. Data are expressed as the -fold induction by comparing the relative luciferase activity from high glucose samples divided by low glucose samples. Values represent means ± S.D. of triplicate samples. B, functional ...
Finding of a novel fungal immunomodulatory protein coding
... (Chang et al., 2009; Lin et al., 2006); in addition, its metabolites can be effective antivirals against the human immunodeficiency virus (HIV) (Gao et al., 2003). Recently, one of these species’ bioactive therapeutic proteins has been cloned and efficiently expressed in molecular vectors (Wu et al ...
... (Chang et al., 2009; Lin et al., 2006); in addition, its metabolites can be effective antivirals against the human immunodeficiency virus (HIV) (Gao et al., 2003). Recently, one of these species’ bioactive therapeutic proteins has been cloned and efficiently expressed in molecular vectors (Wu et al ...
Answers - Study of Life
... Tobacco mosaic virus has RNA rather than DNA as its genetic material. If the RNA genome from a tobacco mosaic virus is mixed with proteins from a human rhinovirus, the result is a mixed virus. If that virus could infect a cell and reproduce, what would you expect the resulting viruses to be like? [a ...
... Tobacco mosaic virus has RNA rather than DNA as its genetic material. If the RNA genome from a tobacco mosaic virus is mixed with proteins from a human rhinovirus, the result is a mixed virus. If that virus could infect a cell and reproduce, what would you expect the resulting viruses to be like? [a ...
PC235: 2008 Lecture 5 Quantitation
... modification changes or as a method for identifying specific results. •Quantitation is normally relative (between samples), but can also be absolute. •Software for analysis of this type of data is still being developed. ...
... modification changes or as a method for identifying specific results. •Quantitation is normally relative (between samples), but can also be absolute. •Software for analysis of this type of data is still being developed. ...
Expression and V (D) J recombination activity of mutated RAG
... encoding the antigen receptors of the developing immune system. Little is known of the specific role these genes play. We have explored the sequences encoding mouse RAG-1 by deleting large parts of the gene and by introducing local sequence changes. We find that a RAG-1 gene with 40% of the coding r ...
... encoding the antigen receptors of the developing immune system. Little is known of the specific role these genes play. We have explored the sequences encoding mouse RAG-1 by deleting large parts of the gene and by introducing local sequence changes. We find that a RAG-1 gene with 40% of the coding r ...
Health relevance of intestinal protein fermentation in young
... formation likely reducing accessibility of susceptible sites to proteases (Carbonaro et al., 1993, 1997). On the other hand, the presence of random coil or unordered secondary structures in animal food proteins has been related to the increment in digestibility. Differences in protein digestibility ...
... formation likely reducing accessibility of susceptible sites to proteases (Carbonaro et al., 1993, 1997). On the other hand, the presence of random coil or unordered secondary structures in animal food proteins has been related to the increment in digestibility. Differences in protein digestibility ...
Inquiry into Life Twelfth Edition
... mRNA 2° structure to control translation initiation • Riboswitches can be used to control translation initiation via mRNA 2° structure – 5’-untranslated region of E. coli thiM mRNA contain a riboswitch – This includes an aptamer that binds thiamine and its metabolite ...
... mRNA 2° structure to control translation initiation • Riboswitches can be used to control translation initiation via mRNA 2° structure – 5’-untranslated region of E. coli thiM mRNA contain a riboswitch – This includes an aptamer that binds thiamine and its metabolite ...
mbe.oxfordjournals.org - Oxford Academic
... Center of Experimental Medicine, Institute of Molecular Cell Biology, Hamburg University, D-20246 Hamburg, Germany Proteomic analyses of the nucleolus have revealed almost 700 functionally diverse proteins implicated in ribosome biogenesis, nucleolar assembly, and regulation of vital cellular proces ...
... Center of Experimental Medicine, Institute of Molecular Cell Biology, Hamburg University, D-20246 Hamburg, Germany Proteomic analyses of the nucleolus have revealed almost 700 functionally diverse proteins implicated in ribosome biogenesis, nucleolar assembly, and regulation of vital cellular proces ...
Course Home - Haldia Institute of Technology
... with an understanding of the limitations FT401.5: Ability to communicate effectively on professional activities with the engineering community to function effectively as an individual or leader in diverse teams in multi-disciplinary settings FT401.6: Apply principles related to complex food solution ...
... with an understanding of the limitations FT401.5: Ability to communicate effectively on professional activities with the engineering community to function effectively as an individual or leader in diverse teams in multi-disciplinary settings FT401.6: Apply principles related to complex food solution ...
Review Evolution of the coordinate regulation of glycolytic enzyme
... glycolysis. Without this switch cells would suffer an immediate mammalian cells and tissues that are extremely oxygenenergy deficit and death at low PO∑. An intriguing feature of the switching is that the same conditions that regulate energy dependent. Exposure to oxygen tensions outside the relativ ...
... glycolysis. Without this switch cells would suffer an immediate mammalian cells and tissues that are extremely oxygenenergy deficit and death at low PO∑. An intriguing feature of the switching is that the same conditions that regulate energy dependent. Exposure to oxygen tensions outside the relativ ...
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats
... animal models [1–7]. These effects are most likely due to the amino acid composition or specific peptides in the different protein sources [1,8–10]. Recently, we have shown that a water-soluble protein extract of chicken (CP) had both hypotriglyceridemic and hypocholesterolemic effects in male Wista ...
... animal models [1–7]. These effects are most likely due to the amino acid composition or specific peptides in the different protein sources [1,8–10]. Recently, we have shown that a water-soluble protein extract of chicken (CP) had both hypotriglyceridemic and hypocholesterolemic effects in male Wista ...
Red blood cells: proteomics, physiology and metabolism
... further information regarding the proteins from which peptides were derived. e.g. molecular weight (MW) in the case of SDS-PAGE, or location when using membrane specific regimes. For SDS/PAGE fractionation, gels are typically sliced at known MW boundaries prior to in-gel proteolytic digestion and su ...
... further information regarding the proteins from which peptides were derived. e.g. molecular weight (MW) in the case of SDS-PAGE, or location when using membrane specific regimes. For SDS/PAGE fractionation, gels are typically sliced at known MW boundaries prior to in-gel proteolytic digestion and su ...
Abstract Here we describe our unprecedented approach in
... nutraceutical intervention in inflammatory bowel disease (IBD) via multi-omics evaluation using dextran sodium sulphate (DSS)-induced colitis. Seven-week-old male C57BL/6J mice were fed either 2% parsley or basal diet and drank normaldrinking-water for 1 week after which colitis was induced by admin ...
... nutraceutical intervention in inflammatory bowel disease (IBD) via multi-omics evaluation using dextran sodium sulphate (DSS)-induced colitis. Seven-week-old male C57BL/6J mice were fed either 2% parsley or basal diet and drank normaldrinking-water for 1 week after which colitis was induced by admin ...
27. GE_7.27 Gluconeo.. - College of Pharmacy at Howard University
... glucose 6-phosphate formation into balance with the rate of its utilization and re-establishing the steady state. What mechanism does this sound like? ...
... glucose 6-phosphate formation into balance with the rate of its utilization and re-establishing the steady state. What mechanism does this sound like? ...
Paracrine signalling

Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.