
Silk-inspired polymers and proteins - Pure
... The natural process of production (known as spinning) for silkworms and spiders is highly complex. Silk proteins are stored within the animal as remarkably highly concentrated protein solutions (up to 50 wt %) without the occurrence of undesirable aggregation. When necessary, the protein solution ca ...
... The natural process of production (known as spinning) for silkworms and spiders is highly complex. Silk proteins are stored within the animal as remarkably highly concentrated protein solutions (up to 50 wt %) without the occurrence of undesirable aggregation. When necessary, the protein solution ca ...
v11a32-hawse pgmkr
... Purpose: In order to identify specific genes that may play important roles in maintaining the specialized functions of lens epithelial and fiber cells, we have analyzed the global gene expression profiles of these two cell types in the human lens. This analysis will also reveal those genes that are ...
... Purpose: In order to identify specific genes that may play important roles in maintaining the specialized functions of lens epithelial and fiber cells, we have analyzed the global gene expression profiles of these two cell types in the human lens. This analysis will also reveal those genes that are ...
(9E10): sc-40 - Santa Cruz Biotechnology
... c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas. The presence of three sequence motifs in the c-Myc COOH termi ...
... c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas. The presence of three sequence motifs in the c-Myc COOH termi ...
Lecture Protein Metabolism
... Sources of Amino Acids for Host Animal 1. Microbial proteins Quantity determined by: a) Fermentability of the feed b) Quantity of feed consumed c) Nitrogen available to microorganisms 2. Undegraded feed proteins (UIP) Quantity will vary in relation to: a) Degradability of feed proteins b) Quantity ...
... Sources of Amino Acids for Host Animal 1. Microbial proteins Quantity determined by: a) Fermentability of the feed b) Quantity of feed consumed c) Nitrogen available to microorganisms 2. Undegraded feed proteins (UIP) Quantity will vary in relation to: a) Degradability of feed proteins b) Quantity ...
Supplementary Data - Institute of Cancer Research
... activated by fungal and Gram-positive infections, while the IMD pathway mainly responds to Gramnegative infections. The IMD pathway is triggered by two peptidoglycan recognition receptors, plasma membrane PGRP-LC or cytosolic PGRP-LE, and activates the NF-κB-like transcription factor Relish 12. PGRP ...
... activated by fungal and Gram-positive infections, while the IMD pathway mainly responds to Gramnegative infections. The IMD pathway is triggered by two peptidoglycan recognition receptors, plasma membrane PGRP-LC or cytosolic PGRP-LE, and activates the NF-κB-like transcription factor Relish 12. PGRP ...
Sulfur Metabolism and Sulfur-Containing Amino Acids
... 3’-phosphoadenosine 5’-phosphosulfate (PAPS) in a variety of homeostatic processes in the body. Sulfur biomolecules exert important functions in all living organisms and their transformations are involved in metals’ transport, free radicals scavenging, tissue integrity protection, enzyme functionali ...
... 3’-phosphoadenosine 5’-phosphosulfate (PAPS) in a variety of homeostatic processes in the body. Sulfur biomolecules exert important functions in all living organisms and their transformations are involved in metals’ transport, free radicals scavenging, tissue integrity protection, enzyme functionali ...
PROTEIN PHOSPHORYLATION AND CELLULAR REGULATION, I by
... a was active in the absence of this nucleotide. Since the concentration of 5’-AMP required for the activity of phosphorylase b was considerably higher ’ than that found in muscle, this form was considered to be physiologically inactive. Phosphorylas e a was thought of as the physiologically active s ...
... a was active in the absence of this nucleotide. Since the concentration of 5’-AMP required for the activity of phosphorylase b was considerably higher ’ than that found in muscle, this form was considered to be physiologically inactive. Phosphorylas e a was thought of as the physiologically active s ...
Jasmonate Biosynthesis, Perception and Function in Plant
... acid) as well as C16-PUFA (hexadecatrienoic acid), in the latter case the intermediate is the so-called dinor-OPDA that may also be metabolized to JA. JA can be further enzymatically converted into numerous derivatives or conjugates, some of which have well-described biological activity such as free ...
... acid) as well as C16-PUFA (hexadecatrienoic acid), in the latter case the intermediate is the so-called dinor-OPDA that may also be metabolized to JA. JA can be further enzymatically converted into numerous derivatives or conjugates, some of which have well-described biological activity such as free ...
Master proper.docx - BORA
... formation. They are active around three days after infection. B cells have three main tasks: generate antibodies against antigens, function as antigenpresenting cells (APC; see below), and develop into memory B cells after activation. The B cell is a key component in humoral immunity (“humours” = ex ...
... formation. They are active around three days after infection. B cells have three main tasks: generate antibodies against antigens, function as antigenpresenting cells (APC; see below), and develop into memory B cells after activation. The B cell is a key component in humoral immunity (“humours” = ex ...
Clathrinmediated transport: assembly required
... Eps 15, synaptotagmin, intersectin and endophilin, among others. Interestingly, most of the proteins described above have long flexible regions that interact with the appendage domains of AP2, as well as with multiple components of the endocytic machinery, to form an interconnected network (Fig 2). ...
... Eps 15, synaptotagmin, intersectin and endophilin, among others. Interestingly, most of the proteins described above have long flexible regions that interact with the appendage domains of AP2, as well as with multiple components of the endocytic machinery, to form an interconnected network (Fig 2). ...
Calcium Signaling. Cell 131: 1047
... (B) The core of the Ca2+ signaling network. In excitatory Ca2+ signaling, plasma membrane ion channels are triggered to open by changes in voltage, or extra- or intracellular ligand binding. When open, ?1 million Ca2+ ions/s/channel flow down the 20,000 fold [Ca2+]i gradient (ECa ? +150 mV), maintai ...
... (B) The core of the Ca2+ signaling network. In excitatory Ca2+ signaling, plasma membrane ion channels are triggered to open by changes in voltage, or extra- or intracellular ligand binding. When open, ?1 million Ca2+ ions/s/channel flow down the 20,000 fold [Ca2+]i gradient (ECa ? +150 mV), maintai ...
Full Text - The International Journal of Developmental Biology
... to the cellular and subcellular levels and, from the 1950’s on, to the molecular level, transformed experimental embryology to developmental biology”. The term “decline” of experimental embryology was falsely interpreted by some authors as a decline of the Freiburg school. That this opinion is wrong ...
... to the cellular and subcellular levels and, from the 1950’s on, to the molecular level, transformed experimental embryology to developmental biology”. The term “decline” of experimental embryology was falsely interpreted by some authors as a decline of the Freiburg school. That this opinion is wrong ...
Review the mechanism of protein folding
... polypeptide chain during translation after the synthesis some protein released for expression and some may attached for some specialised folding and most destabilise polypeptide chain degraded by chaperones (Tomala, Korona ...
... polypeptide chain during translation after the synthesis some protein released for expression and some may attached for some specialised folding and most destabilise polypeptide chain degraded by chaperones (Tomala, Korona ...
Review
... (B) The core of the Ca2+ signaling network. In excitatory Ca2+ signaling, plasma membrane ion channels are triggered to open by changes in voltage, or extra- or intracellular ligand binding. When open, ?1 million Ca2+ ions/s/channel flow down the 20,000 fold [Ca2+]i gradient (ECa ? +150 mV), maintai ...
... (B) The core of the Ca2+ signaling network. In excitatory Ca2+ signaling, plasma membrane ion channels are triggered to open by changes in voltage, or extra- or intracellular ligand binding. When open, ?1 million Ca2+ ions/s/channel flow down the 20,000 fold [Ca2+]i gradient (ECa ? +150 mV), maintai ...
Chapter 8
... Gluconeogenesis is the formation of new glucose molecules from precursors in the liver Precursor molecules include lactate, pyruvate, and ...
... Gluconeogenesis is the formation of new glucose molecules from precursors in the liver Precursor molecules include lactate, pyruvate, and ...
Research Applications Of Proteolytic Enzymes In Molecular Biology
... concentrations) can diffuse from the organic phase into the water until the equilibrium is reached; the enzyme-catalyzed synthesis is followed by the diffusion of the products back into the organic phase. The organic phase reduces the dielectric constant of the medium and thus the acidity of the car ...
... concentrations) can diffuse from the organic phase into the water until the equilibrium is reached; the enzyme-catalyzed synthesis is followed by the diffusion of the products back into the organic phase. The organic phase reduces the dielectric constant of the medium and thus the acidity of the car ...
Metabolome Phenotyping of Inorganic Carbon Limitation in Cells of
... consideration. These analyses demonstrated that in the above-mentioned mutants compared to wild type and shifted from HC to LC conditions, respectively, a major reprogramming of Synechocystis metabolism occurred in response to reduced availability of Ci (Fig. 1). Independent component analysis (ICA) ...
... consideration. These analyses demonstrated that in the above-mentioned mutants compared to wild type and shifted from HC to LC conditions, respectively, a major reprogramming of Synechocystis metabolism occurred in response to reduced availability of Ci (Fig. 1). Independent component analysis (ICA) ...
Journal of Bacteriology
... iron-sulfur protein (dinitrogenase reductase) with a single type of subunit (9). Both proteins are essential for enzymic activity together with ATP (which is hydrolyzed to ADP + ...
... iron-sulfur protein (dinitrogenase reductase) with a single type of subunit (9). Both proteins are essential for enzymic activity together with ATP (which is hydrolyzed to ADP + ...
Chloroplasts at work during plant innate immunity
... 3846 | Serrano et al. multitude of intracellular signals in order to communicate those perturbations to other organelles (Padmanabhan and Dinesh-Kumar, 2010; Bobik and Burch-Smith, 2015). The chloroplast, together with the nucleus, cell membrane, and endoplasmic reticulum (ER), plays a critical r ...
... 3846 | Serrano et al. multitude of intracellular signals in order to communicate those perturbations to other organelles (Padmanabhan and Dinesh-Kumar, 2010; Bobik and Burch-Smith, 2015). The chloroplast, together with the nucleus, cell membrane, and endoplasmic reticulum (ER), plays a critical r ...
Lateral gene transfer and the evolution of plastid
... Volvox carteri, and D. salina, with this clade forming a sister group to the streptophytes. The phylogeny of the ⬘ subunit of ATP synthase shows the same pattern (Fig. 2B), consistent with previous analyses of plastid- and nucleomorph-encoded genes (12, 13, 15). Other B. natans proteins (32%) produ ...
... Volvox carteri, and D. salina, with this clade forming a sister group to the streptophytes. The phylogeny of the ⬘ subunit of ATP synthase shows the same pattern (Fig. 2B), consistent with previous analyses of plastid- and nucleomorph-encoded genes (12, 13, 15). Other B. natans proteins (32%) produ ...
Molecule Pages - Berkeley Database Group
... databases will become scientific journals and journals will become databases. Biologists will be greatly empowered, and bioinformatics will continue its long evolution.” ...
... databases will become scientific journals and journals will become databases. Biologists will be greatly empowered, and bioinformatics will continue its long evolution.” ...
Role of Streptococcus sanguinis sortase A in bacterial
... 10557. Lane 4: S. pyogenes strain SSI-1. Strain SSI-1 is known to express the Fn-binding protein FbaB [16]. ...
... 10557. Lane 4: S. pyogenes strain SSI-1. Strain SSI-1 is known to express the Fn-binding protein FbaB [16]. ...
The Predicted Candidates of Arabidopsis Plastid Inner Envelope
... homologs, 541 proteins remained as potential candidates for Arabidopsis plastid envelope membrane proteins (AtPEM). It is important to note that these are predicted to be integral membrane protein candidates and the candidate list will contain omissions and inclusions of various types. First, as men ...
... homologs, 541 proteins remained as potential candidates for Arabidopsis plastid envelope membrane proteins (AtPEM). It is important to note that these are predicted to be integral membrane protein candidates and the candidate list will contain omissions and inclusions of various types. First, as men ...
The lysosome as a command-and-control center for cellular
... “top-down” manner, as they involve the engagement of a growth factor ligand to its receptor on the cell surface, followed by signal propagation inside the cell (Taniguchi et al., 2006). Growth factor–derived signals trigger changes in the rate of biochemical reactions occurring in the cytoplasm and ...
... “top-down” manner, as they involve the engagement of a growth factor ligand to its receptor on the cell surface, followed by signal propagation inside the cell (Taniguchi et al., 2006). Growth factor–derived signals trigger changes in the rate of biochemical reactions occurring in the cytoplasm and ...
Paracrine signalling

Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.