
CHAPTER 3: Early tissue patterning is recreated by MEFs in... Figure 5: Osteogenic and chondrogenic differentiation of MEFs cultured in
... Moreover, a dose-response inhibitory effect on the 3D-bilateral structure development can be observed when diluted concentrations of Staurosporine are added to the cultures (Figure 2 F). These results indicate that during this morphogenetic event the cell density increases not only by contraction bu ...
... Moreover, a dose-response inhibitory effect on the 3D-bilateral structure development can be observed when diluted concentrations of Staurosporine are added to the cultures (Figure 2 F). These results indicate that during this morphogenetic event the cell density increases not only by contraction bu ...
The proteome of Saccharomyces cerevisiae mitochondria
... of the known mitochondrial proteins. Several more proteins are likely candidates for a dual localization (36, 37). (v) We synthesized a number of the proteins, which had been localized to other compartments or had not been localized so far, in rabbit reticulocyte lysate in the presence of [35S]methi ...
... of the known mitochondrial proteins. Several more proteins are likely candidates for a dual localization (36, 37). (v) We synthesized a number of the proteins, which had been localized to other compartments or had not been localized so far, in rabbit reticulocyte lysate in the presence of [35S]methi ...
Src protein–tyrosine kinase structure and regulation
... than the wild type enzyme and can induce anchorage-independent growth in vitro and tumors in vivo [18,19]. Tyr527 phosphorylation results from the action of other protein–tyrosine kinases including Csk and Chk [20,21]. Src undergoes an intermolecular autophosphorylation at tyrosine 416; this residue ...
... than the wild type enzyme and can induce anchorage-independent growth in vitro and tumors in vivo [18,19]. Tyr527 phosphorylation results from the action of other protein–tyrosine kinases including Csk and Chk [20,21]. Src undergoes an intermolecular autophosphorylation at tyrosine 416; this residue ...
BMC Bioinformatics
... Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryotic host cytosol and facilitates bacterial infection. For many plant and animal pathogens, T3SS is indispensable for diseas ...
... Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryotic host cytosol and facilitates bacterial infection. For many plant and animal pathogens, T3SS is indispensable for diseas ...
Calcium Activation of ERK Mediated by Calmodulin Kinase I
... most closely related to the c-Jun N-terminal kinase (JNK) and the stress-activated kinase, p38 (1). ERK activation plays a role, largely through regulation of gene transcription, in a number of cellular processes including cellular proliferation, DNA synthesis, differentiation, and cellular survival ...
... most closely related to the c-Jun N-terminal kinase (JNK) and the stress-activated kinase, p38 (1). ERK activation plays a role, largely through regulation of gene transcription, in a number of cellular processes including cellular proliferation, DNA synthesis, differentiation, and cellular survival ...
Prediction of B cell epitopes
... design Predictions of B cell epitopes may also be valuable for interpretation of results from experiments based on antibody affinity binding such as ELISA, RIA and western blotting ...
... design Predictions of B cell epitopes may also be valuable for interpretation of results from experiments based on antibody affinity binding such as ELISA, RIA and western blotting ...
Lecture 5 Tues 4-11-06
... 2. Require a transit peptide signal for protein import. d. Apicoplasts are required for infectivity. e. May be excellent drug targets because they contain prokaryotic metabolic pathways reflecting their origins. ...
... 2. Require a transit peptide signal for protein import. d. Apicoplasts are required for infectivity. e. May be excellent drug targets because they contain prokaryotic metabolic pathways reflecting their origins. ...
Adipocyte metabolic pathways regulated by diet control
... invertebrates to mammals (Ables et al. 2012). There is also a link between intrinsic metabolic changes ...
... invertebrates to mammals (Ables et al. 2012). There is also a link between intrinsic metabolic changes ...
Folic Acid and Its Receptors - OPUS
... gene is predicted to play a role in binding retinoids, as it shares some homology with riboflavin binding proteins (35). There is at least one known reduced folate carrier protein, SLC19A1, which is also known as reduced folate carrier (RFC), FOLT, and Intestinal folate carrier (41). This protein bi ...
... gene is predicted to play a role in binding retinoids, as it shares some homology with riboflavin binding proteins (35). There is at least one known reduced folate carrier protein, SLC19A1, which is also known as reduced folate carrier (RFC), FOLT, and Intestinal folate carrier (41). This protein bi ...
Drosophila - AOS-HCI-2011-Research
... cell death) of cancer tumor cells by increasing focal adhesion kinase. Focal adhesion kinase, when activated, is a protein that promotes cell life. In cancer research when different factors are looked at in isolation, stress has been found to play a main role in tumor cell proliferation. This is bec ...
... cell death) of cancer tumor cells by increasing focal adhesion kinase. Focal adhesion kinase, when activated, is a protein that promotes cell life. In cancer research when different factors are looked at in isolation, stress has been found to play a main role in tumor cell proliferation. This is bec ...
Identification of TIpC, a novel 62 kDa MCP
... their ancient origin, which probably predates the separation of these two lines of descent. MCPs are also known to exist in the Gram-positive organism Bacillzls sztbtilis. Biochemical evidence suggested that there were three MCPs, with molecular masses ranging from 77 to 97 kDa (Bedale etal., 1988; ...
... their ancient origin, which probably predates the separation of these two lines of descent. MCPs are also known to exist in the Gram-positive organism Bacillzls sztbtilis. Biochemical evidence suggested that there were three MCPs, with molecular masses ranging from 77 to 97 kDa (Bedale etal., 1988; ...
Statistical analysis of DNA microarray data
... recognition. Today, the terms threading and fold recognition are frequently (though somewhat incorrectly) used interchangeably. The basic idea is that the target sequence (the protein sequence for which the structure is being predicted) is threaded through the backbone structures of a collection of ...
... recognition. Today, the terms threading and fold recognition are frequently (though somewhat incorrectly) used interchangeably. The basic idea is that the target sequence (the protein sequence for which the structure is being predicted) is threaded through the backbone structures of a collection of ...
Biochemical fossils of the ancient transition from geoenergetics to
... events of fusion of these genes occurred and combinations of pabAB, pabBC or even pabABC have been reported [24,200]. Although methanogens can incorporate pABA into methanopterin if provided in the culture medium [205,212], genes from this pathway are absent and instead of pABA, methanogens incorpor ...
... events of fusion of these genes occurred and combinations of pabAB, pabBC or even pabABC have been reported [24,200]. Although methanogens can incorporate pABA into methanopterin if provided in the culture medium [205,212], genes from this pathway are absent and instead of pABA, methanogens incorpor ...
EVIDENCE FOR TWO DISTINCT CLASSES OF STREPTOCOCCAL
... Correlations can be made between particular M serotypes and other physicochemical properties of group A streptococci. M-associated protein (MAP) was identified in the 1970s as a surface component of M protein-bearing organisms that co-purifies with the type-specific substance (10, 13, 14) . Isolates ...
... Correlations can be made between particular M serotypes and other physicochemical properties of group A streptococci. M-associated protein (MAP) was identified in the 1970s as a surface component of M protein-bearing organisms that co-purifies with the type-specific substance (10, 13, 14) . Isolates ...
Gene Section TYR (tyrosinase (oculocutaneous albinism IA)) Atlas of Genetics and Cytogenetics
... longevity of melanocytes, these cells are considered to have a greater mutagenic burden. This burden is also greater due to the position of melanocytes within the skin and their exposure to UV light. Tyrosinase enzymatic activity has been found to be associated with a better prognosis due to its ass ...
... longevity of melanocytes, these cells are considered to have a greater mutagenic burden. This burden is also greater due to the position of melanocytes within the skin and their exposure to UV light. Tyrosinase enzymatic activity has been found to be associated with a better prognosis due to its ass ...
Ornithodoros savignyi CHAPTER 2 SIGNALING PATHWAYS REGULATING PROTEIN SECRETION FROM
... cAMP subsequently binds to a cAMP-dependent protein kinase (R2C2) whose catalytic subunit (C), when activated by the dissociation of the regulatory dimer as R2•cAMP4, activates various cellular proteins by catalyzing their phosphorylation (Figure 2.5). ...
... cAMP subsequently binds to a cAMP-dependent protein kinase (R2C2) whose catalytic subunit (C), when activated by the dissociation of the regulatory dimer as R2•cAMP4, activates various cellular proteins by catalyzing their phosphorylation (Figure 2.5). ...
107105_pku
... This photo was taken at my wedding a few years ago. I have PKU. I was diagnosed on the 3rd day of my life when treatment with the diet began. I stayed on the diet for 16 years. After I married and when my husband and I decided we would like to have a child, I went back on the diet before conception ...
... This photo was taken at my wedding a few years ago. I have PKU. I was diagnosed on the 3rd day of my life when treatment with the diet began. I stayed on the diet for 16 years. After I married and when my husband and I decided we would like to have a child, I went back on the diet before conception ...
Caprotein by Mt. Capra Premium Goat
... This provides many advantages over vegetarian sources (such as soy) because they are typically low in one or more of the amino acids even though overall protein content is high. Why are whole proteins superior to isolated proteins? Protein supplements are often offered as whey protein isolates becau ...
... This provides many advantages over vegetarian sources (such as soy) because they are typically low in one or more of the amino acids even though overall protein content is high. Why are whole proteins superior to isolated proteins? Protein supplements are often offered as whey protein isolates becau ...
Lipidomics in Cell Regulation
... Ensure a stable cellular environment Provides a 2-D space for efficient chemical reaction The lipids creates an optimal environment for protein function in the membrane More than 300 lipid species are found in the plasma membrane ...
... Ensure a stable cellular environment Provides a 2-D space for efficient chemical reaction The lipids creates an optimal environment for protein function in the membrane More than 300 lipid species are found in the plasma membrane ...
Additional file 1
... Additional File 1 Sequence homology: Functional characterization of transcript derived fragments (TDFs) based on BLAST X and TAIR FASTA analysis ...
... Additional File 1 Sequence homology: Functional characterization of transcript derived fragments (TDFs) based on BLAST X and TAIR FASTA analysis ...
Chapters11-Glycolysis-2014
... The citric acid cycle, aka the tricarboxylic acid cycle (TCA), or the Krebs cycle: Series of chemical reactions used by all aerobic organisms to generate energy. It works by the oxidation of acetate derived from carbohydrates, fats and proteins into CO2 and G in the form of ATP. The cycle also provi ...
... The citric acid cycle, aka the tricarboxylic acid cycle (TCA), or the Krebs cycle: Series of chemical reactions used by all aerobic organisms to generate energy. It works by the oxidation of acetate derived from carbohydrates, fats and proteins into CO2 and G in the form of ATP. The cycle also provi ...
Candidate genes and single nucleotide polymorphisms associated
... and their corresponding P-values were imported into the IPA software and the parameters were set to allow the network to include indirect relationships between the imported genes and genes in the database. Indirect relationships would assist in the identification of other genes that were not among t ...
... and their corresponding P-values were imported into the IPA software and the parameters were set to allow the network to include indirect relationships between the imported genes and genes in the database. Indirect relationships would assist in the identification of other genes that were not among t ...
Dynamics of the trp Operon
... The five genes are transcribed as a single mRNA molecule, allowing their expression to be controlled coordinately. There is one promoter. Within the promoter is an operator. Tryptophan repressor can bind to operator and deny access to RNA polymerase. ...
... The five genes are transcribed as a single mRNA molecule, allowing their expression to be controlled coordinately. There is one promoter. Within the promoter is an operator. Tryptophan repressor can bind to operator and deny access to RNA polymerase. ...
everything you need to know about protein - Bio
... this lost tissue as quickly as possible. One type of protein may offer specific benefits that another protein may not. Since your body uses the different attributes of proteins for a wide variety of functions, it is best to consume several types of protein each day. For this reason Bio-Synergy uses ...
... this lost tissue as quickly as possible. One type of protein may offer specific benefits that another protein may not. Since your body uses the different attributes of proteins for a wide variety of functions, it is best to consume several types of protein each day. For this reason Bio-Synergy uses ...
Amyotrophic lateral sclerosis: Protein
... be very powerful at providing clues or answers to many crucial biological questions, including changes in protein expression, PTM, protein-protein interactions and protein activities. Traditionally, alterations in protein expression have been analyzed primarily by 2-DE-based methods. More recently, ...
... be very powerful at providing clues or answers to many crucial biological questions, including changes in protein expression, PTM, protein-protein interactions and protein activities. Traditionally, alterations in protein expression have been analyzed primarily by 2-DE-based methods. More recently, ...
Paracrine signalling

Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.