Flamingo controls the planar polarity of sensory
... The sensory bristles of the fruit fly Drosophila are organized in a polarized fashion such that bristles on the thorax point posteriorly. These bristles are derived from asymmetric division of sensory organ precursors (SOPs). The Numb protein, which is localized asymmetrically in a cortical crescent ...
... The sensory bristles of the fruit fly Drosophila are organized in a polarized fashion such that bristles on the thorax point posteriorly. These bristles are derived from asymmetric division of sensory organ precursors (SOPs). The Numb protein, which is localized asymmetrically in a cortical crescent ...
HYPOXIA AND THE METABOLIC PHENOTYPE OF PROSTATE CANCER CELLS
... Many thanks to Chris Moyes (The Big Kahuna, Boss, Wizard, Professor M, P Moyes) for being the best supervisor, mentor, and friend I could have hoped for. I would also like to thank my fellow members of the Moyes lab, for I would not have made it through without them! Thanks to Chris Le Moine for tea ...
... Many thanks to Chris Moyes (The Big Kahuna, Boss, Wizard, Professor M, P Moyes) for being the best supervisor, mentor, and friend I could have hoped for. I would also like to thank my fellow members of the Moyes lab, for I would not have made it through without them! Thanks to Chris Le Moine for tea ...
Journal of Agricultural and Food Chemistry
... or the use of microsatellites (14). The use of proteins is limited. There are few publications connected with the taxonomy of plants from sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) analysis (15, 16). There are two types of protein markers: the immunochemical, or serological ...
... or the use of microsatellites (14). The use of proteins is limited. There are few publications connected with the taxonomy of plants from sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) analysis (15, 16). There are two types of protein markers: the immunochemical, or serological ...
33_organelles.txt 3/25/2010 Limited proteolysis, phosphorylation
... to diseases such as Kearn-Sayre syndrome. Its DNA typically consists of five to ten copies, all inherited from the mother, and when they divide these copies are randomly distributed between the offspring. Some theories hold that its DNA is derived from a single source called "Eve". FTP, what are the ...
... to diseases such as Kearn-Sayre syndrome. Its DNA typically consists of five to ten copies, all inherited from the mother, and when they divide these copies are randomly distributed between the offspring. Some theories hold that its DNA is derived from a single source called "Eve". FTP, what are the ...
Protein reutilisation in corms of Colchicum autumnale
... by proteins, we were interested in nitrogen remobilisation during the annual life cycle of C. autumnale. In this context the content of soluble and insoluble proteins were measured in parallel with determination of some exo- and endopeptidase activities. Our results indicate that the continual prote ...
... by proteins, we were interested in nitrogen remobilisation during the annual life cycle of C. autumnale. In this context the content of soluble and insoluble proteins were measured in parallel with determination of some exo- and endopeptidase activities. Our results indicate that the continual prote ...
Small-molecule metabolism: an enzyme mosaic
... Fig. 3. Fucose, rhamnose and L-arabinose catabolism. (a) Fucose and rhamnose. A superpathway exists in EcoCyc that consists of the fucose and rhamnose catabolism subpathways. An example of serial recruitment and of ‘parallel’ enzymes is shown (boxed). Serial recruitment has occurred because fucK (L- ...
... Fig. 3. Fucose, rhamnose and L-arabinose catabolism. (a) Fucose and rhamnose. A superpathway exists in EcoCyc that consists of the fucose and rhamnose catabolism subpathways. An example of serial recruitment and of ‘parallel’ enzymes is shown (boxed). Serial recruitment has occurred because fucK (L- ...
VEGF and endochondral bone formation
... hypothesis (Descalzi et al., 1995): single hypertrophic chondrocytes in suspension have inhibitory effects on endothelial cell migration and invasion; when supplemented with ascorbic acid, a condition that allows organization of an extracellular matrix totally resembling in vivo cartilage, hypertrop ...
... hypothesis (Descalzi et al., 1995): single hypertrophic chondrocytes in suspension have inhibitory effects on endothelial cell migration and invasion; when supplemented with ascorbic acid, a condition that allows organization of an extracellular matrix totally resembling in vivo cartilage, hypertrop ...
Biopathways Representation and Simulation on Hybrid Functional
... Cell for modeling even simple biopathways. The switching mechanism of the λ phage is also simulated with LISP language description [14] where knowledge about the biopathway is elegantly represented with LISP and is simultaneously simulated with LISP system. BioSpice [45] is a similar system whose id ...
... Cell for modeling even simple biopathways. The switching mechanism of the λ phage is also simulated with LISP language description [14] where knowledge about the biopathway is elegantly represented with LISP and is simultaneously simulated with LISP system. BioSpice [45] is a similar system whose id ...
The role of AMP-activated protein kinase in the coordination of
... major role of AMPK in the regulation of PFK-2 activity. Moreover, AMPK increase hexokinase-2 (HK-2) transcription, an enzyme responsible for glucose-6-phosphate synthesis, by phosphorylating cAMP response element-binding (CREB) at Ser133 (111, 116). Furthermore, AMPK phosphorylates and inactivates g ...
... major role of AMPK in the regulation of PFK-2 activity. Moreover, AMPK increase hexokinase-2 (HK-2) transcription, an enzyme responsible for glucose-6-phosphate synthesis, by phosphorylating cAMP response element-binding (CREB) at Ser133 (111, 116). Furthermore, AMPK phosphorylates and inactivates g ...
Supplemental Materials
... the mutated hemoglobin are more protected from malaria than those with all normal red blood cells. However, if a person is homozygous for the mutated hemoglobin then they could die from sickle cell anemia. The person with 1 copy of each allele is heterozygous and is protected from both malaria and s ...
... the mutated hemoglobin are more protected from malaria than those with all normal red blood cells. However, if a person is homozygous for the mutated hemoglobin then they could die from sickle cell anemia. The person with 1 copy of each allele is heterozygous and is protected from both malaria and s ...
Expression of 35S::Pto Globally Activates
... several cDNA clones were highly redundant in the library. These encode catalases, a Gly-rich cell wall protein, and several members of the PR1 family of proteins. These cDNA clones, together with several known tomato PR gene cDNA clones (PR1a1, PR1b1, GluB, Osmotin, and Chia; cited in Tang et al., 1 ...
... several cDNA clones were highly redundant in the library. These encode catalases, a Gly-rich cell wall protein, and several members of the PR1 family of proteins. These cDNA clones, together with several known tomato PR gene cDNA clones (PR1a1, PR1b1, GluB, Osmotin, and Chia; cited in Tang et al., 1 ...
The significance of biochemical and molecular sample integrity in
... While it is generally expected that the postmortem interval may significantly affect the preservation of some brain neuropeptides and catecholamines, it is commonly thought that proteins are relatively stable postmortem [2–4]. However, protein recoveries from human postmortem tissue have displayed h ...
... While it is generally expected that the postmortem interval may significantly affect the preservation of some brain neuropeptides and catecholamines, it is commonly thought that proteins are relatively stable postmortem [2–4]. However, protein recoveries from human postmortem tissue have displayed h ...
Metabolism of Red Blood Cells (RBCs)
... For that RBCs must be easily & reversibly deformable. Its membrane must be both fluid & flexible . • About 50% of membrane is protein, 40% is fat & up to 10% is carbohydrate. ...
... For that RBCs must be easily & reversibly deformable. Its membrane must be both fluid & flexible . • About 50% of membrane is protein, 40% is fat & up to 10% is carbohydrate. ...
RBCs metabolism
... For that RBCs must be easily & reversibly deformable. Its membrane must be both fluid & flexible . • About 50% of membrane is protein, 40% is fat & up to 10% is carbohydrate. ...
... For that RBCs must be easily & reversibly deformable. Its membrane must be both fluid & flexible . • About 50% of membrane is protein, 40% is fat & up to 10% is carbohydrate. ...
A first attempt to elucidate the amino acid sequence of some lichen
... to form a new biological entity different from its individual components. Recognition mechanisms used by lichens are based on the production and secretion of fungal lectins as signalling molecules (Kardish et al., 1991), which therefore develop arginase enzymatic activity (Molina et al., 1993). Wher ...
... to form a new biological entity different from its individual components. Recognition mechanisms used by lichens are based on the production and secretion of fungal lectins as signalling molecules (Kardish et al., 1991), which therefore develop arginase enzymatic activity (Molina et al., 1993). Wher ...
148 - Blue Ridge Institute for Medical Research
... kinases contain a K/E/D/D signature sequence that plays important structural and catalytic roles. Protein kinases contain hydrophobic catalytic and regulatory spines and collateral shell residues that are required to assemble the active enzyme. There are two general kinds of conformational changes a ...
... kinases contain a K/E/D/D signature sequence that plays important structural and catalytic roles. Protein kinases contain hydrophobic catalytic and regulatory spines and collateral shell residues that are required to assemble the active enzyme. There are two general kinds of conformational changes a ...
Tilting Plant Metabolism for Improved Metabolite Biosynthesis and
... Although the exact roles of many alkaloids are not well understood, the compounds are believed to play an important ecological role, enabling the producing organism to interact defensively with its environment. They confer a survival benefit through their ability to bind to cellular targets in antag ...
... Although the exact roles of many alkaloids are not well understood, the compounds are believed to play an important ecological role, enabling the producing organism to interact defensively with its environment. They confer a survival benefit through their ability to bind to cellular targets in antag ...
Aromatic amino acid metabolism
... The life expectancy is drastically shortened. Diagnostic criteria: phenylalanine level in the blood FeCl3 test DNA probes (prenatal) ...
... The life expectancy is drastically shortened. Diagnostic criteria: phenylalanine level in the blood FeCl3 test DNA probes (prenatal) ...
Platelets
... membrane by phospholipase and then rapidly oxidized by the enzyme cyclo oxygenase to PGG2 & PGH2 In the platelets:PGG2 is converted to TX A2 a highly potent platelet aggregator and constrictor of arterial muscle In the arterial endothelium: PGG2 & PGH2 are converted to prostacyclin a potent ...
... membrane by phospholipase and then rapidly oxidized by the enzyme cyclo oxygenase to PGG2 & PGH2 In the platelets:PGG2 is converted to TX A2 a highly potent platelet aggregator and constrictor of arterial muscle In the arterial endothelium: PGG2 & PGH2 are converted to prostacyclin a potent ...
Basic mechanisms of normal and abnormal
... of food intake and intestinal feedback regulation of GI function. These observations have led to the notion of nutrient sensors in the GI tract. Vagal afferents innervating the proximal GI tract are activated by the presence of lumenal nutrients, leading to the activation of CNS pathways involved in ...
... of food intake and intestinal feedback regulation of GI function. These observations have led to the notion of nutrient sensors in the GI tract. Vagal afferents innervating the proximal GI tract are activated by the presence of lumenal nutrients, leading to the activation of CNS pathways involved in ...
The head organizer in Hydra
... when hand-fed in that their shape and size as well as epithelial cell division and the resulting tissue movements as well as bud formation are normal (Sugiyama and Fujisawa, 1978). The signals produced by the head organizer In the context of the tissue dynamics of an adult Hydra, the head organizer ...
... when hand-fed in that their shape and size as well as epithelial cell division and the resulting tissue movements as well as bud formation are normal (Sugiyama and Fujisawa, 1978). The signals produced by the head organizer In the context of the tissue dynamics of an adult Hydra, the head organizer ...
Fatty acid transport proteins: a current view of a
... utilizing organs. The differential distribution of glucose among organs is facilitated by tissue-specific expression of a family of different glucose transporters, in addition to different abilities to respond to insulin changes34. The mechanisms by which the flux of LCFAs into organs is regulated a ...
... utilizing organs. The differential distribution of glucose among organs is facilitated by tissue-specific expression of a family of different glucose transporters, in addition to different abilities to respond to insulin changes34. The mechanisms by which the flux of LCFAs into organs is regulated a ...
Design and Evolution of Artificial M13 Coat Proteins
... (Webster, 1996). Integration of P8 into the viral coat requires interactions between the positively charged cytoplasmic domain and the negatively charged DNA, and also, interactions between the central hydrophobic domains of adjacent P8 molecules. These interactions also maintain the integrity of th ...
... (Webster, 1996). Integration of P8 into the viral coat requires interactions between the positively charged cytoplasmic domain and the negatively charged DNA, and also, interactions between the central hydrophobic domains of adjacent P8 molecules. These interactions also maintain the integrity of th ...
Protein
... Diabetes; the amount of protein in the diet doesn't seem to adversely affect the development of type 2 (adult-onset) diabetes, although research in this area is ongoing Cancer; there's no good evidence that eating a little protein or a lot of it influences ...
... Diabetes; the amount of protein in the diet doesn't seem to adversely affect the development of type 2 (adult-onset) diabetes, although research in this area is ongoing Cancer; there's no good evidence that eating a little protein or a lot of it influences ...
Paracrine signalling
Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.