
Protein
... Any parts of proteins that are not digested and absorbed in the small intestine continue on through the large intestine. People with celiac disease, for example, cannot properly digest gluten—a protein found in wheat, barley, rye, and oats. Unless treated with a gluten-free diet, people with celiac ...
... Any parts of proteins that are not digested and absorbed in the small intestine continue on through the large intestine. People with celiac disease, for example, cannot properly digest gluten—a protein found in wheat, barley, rye, and oats. Unless treated with a gluten-free diet, people with celiac ...
Xenopus ADAM13 and ADAM19 are Important for Proper
... Some of the unpublished work discussed in this thesis focuses on the roles of ADAM13 and ADAM19 in the dorsal mesoderm during gastrulation. Specific emphasis is made on investigating the axial mesoderm during notochord formation. I show that ADAM19 affects gene expression important for the A-P polar ...
... Some of the unpublished work discussed in this thesis focuses on the roles of ADAM13 and ADAM19 in the dorsal mesoderm during gastrulation. Specific emphasis is made on investigating the axial mesoderm during notochord formation. I show that ADAM19 affects gene expression important for the A-P polar ...
Dr. Murad`s Abstract
... The role of nitric oxide in cellular signaling in the past three decades has become one of the most rapidly growing areas in biology. Nitric oxide (NO) is a gas and a free radical with an unshared electron that can regulate an ever-growing list of biological processes. Nitric oxide is formed from L- ...
... The role of nitric oxide in cellular signaling in the past three decades has become one of the most rapidly growing areas in biology. Nitric oxide (NO) is a gas and a free radical with an unshared electron that can regulate an ever-growing list of biological processes. Nitric oxide is formed from L- ...
Protein Foods
... lean meat and the second number is the percentage of fat (example 85/15). Ideally, you would like the second number to be as low as possible. However, many times those with less fat are more expensive; it is fine to purchase ground beef that is higher in fat but the fat should be drained after cooki ...
... lean meat and the second number is the percentage of fat (example 85/15). Ideally, you would like the second number to be as low as possible. However, many times those with less fat are more expensive; it is fine to purchase ground beef that is higher in fat but the fat should be drained after cooki ...
Optimizing cofactor availability for the production of recombinant
... production landscapes from microscale cultivations using 1 mM FeSO4-supplemented medium. Error bars are standard deviations from all measured clones of a landscape. Average activity from strains producing HRP alone was set to 100%. In addition to strong constitutive co-overexpression of either HEM1 ...
... production landscapes from microscale cultivations using 1 mM FeSO4-supplemented medium. Error bars are standard deviations from all measured clones of a landscape. Average activity from strains producing HRP alone was set to 100%. In addition to strong constitutive co-overexpression of either HEM1 ...
Expression of biologically active mouse ciliary neutrophic factor
... embryo. It has been evaluated for the treatment of neurodegenerative diseases. CNTF also acts on non-neuronal cells such as oligodendrocytes, astrocytes, adipocytes and skeletal muscles cells. CNTF has regulatory effects on body weight and is currently in clinical trial for the treatment of diabetes ...
... embryo. It has been evaluated for the treatment of neurodegenerative diseases. CNTF also acts on non-neuronal cells such as oligodendrocytes, astrocytes, adipocytes and skeletal muscles cells. CNTF has regulatory effects on body weight and is currently in clinical trial for the treatment of diabetes ...
Identification of a novel N-terminal hydrophobic sequence that
... the bilayer and subsequently bud into the cytoplasm (van Meer, 2001). Virtually all eukaryotic and many bacterial cells can accumulate lipid droplets, which suggests that the adiposome machinery is common to all cells. All organelles contain core molecules that govern their biogenesis and function, ...
... the bilayer and subsequently bud into the cytoplasm (van Meer, 2001). Virtually all eukaryotic and many bacterial cells can accumulate lipid droplets, which suggests that the adiposome machinery is common to all cells. All organelles contain core molecules that govern their biogenesis and function, ...
Chapter 3 Part 1
... • Cells are the smallest units that perform all vital physiological functions • Each cell maintains homeostasis at the cellular level ...
... • Cells are the smallest units that perform all vital physiological functions • Each cell maintains homeostasis at the cellular level ...
A complete shikimate pathway in Toxoplasma gondii: an ancient
... sequence positions that could not be aligned with confidence such as hyper-variable regions of the protein sequence. The dehydroquinase portion of the AROM is highly variable with few conserved characters identifiable; a reasonable alignment and character sampling could not be achieved, preventing p ...
... sequence positions that could not be aligned with confidence such as hyper-variable regions of the protein sequence. The dehydroquinase portion of the AROM is highly variable with few conserved characters identifiable; a reasonable alignment and character sampling could not be achieved, preventing p ...
Mitochondrial protein acetylation regulates metabolism
... group to the ε-amino group of lysine residues that occurs on a wide array of proteins. This simple modification neutralizes the positive charge of the lysine residue, potentially altering its propensity to interact with nearby amino acids or other proteins. In this way, acetylation can influence mul ...
... group to the ε-amino group of lysine residues that occurs on a wide array of proteins. This simple modification neutralizes the positive charge of the lysine residue, potentially altering its propensity to interact with nearby amino acids or other proteins. In this way, acetylation can influence mul ...
Inborn defects in the antioxidant systems of human red blood cells
... lead to amino acid substitutions that destabilize the enzyme [36]. This instability of G6PD usually becomes apparent only in the long-living RBCs, which do not have the potential for protein synthesis. In other tissues, renewal of the enzyme can overcome its instability. Nonsense or frameshift mutat ...
... lead to amino acid substitutions that destabilize the enzyme [36]. This instability of G6PD usually becomes apparent only in the long-living RBCs, which do not have the potential for protein synthesis. In other tissues, renewal of the enzyme can overcome its instability. Nonsense or frameshift mutat ...
Isolation, Properties and a Possible Function of a Water
... (Fig. 3B). The different Chi a forms are ascribed to different natures or modes of interactions of Chi a with the protein molecule. When the Chi a to protein ratio of about one is taken into account, a simple explanation would be that the CP673 preparation is a mixture of the protein molecules that ...
... (Fig. 3B). The different Chi a forms are ascribed to different natures or modes of interactions of Chi a with the protein molecule. When the Chi a to protein ratio of about one is taken into account, a simple explanation would be that the CP673 preparation is a mixture of the protein molecules that ...
Chapter 8 - HCC Learning Web
... The word spontaneous describes a process that can occur without an input of energy. Spontaneous processes need not occur quickly. Some spontaneous processes are instantaneous, such as an explosion. Some are very slow, such as the rusting of an old car. ...
... The word spontaneous describes a process that can occur without an input of energy. Spontaneous processes need not occur quickly. Some spontaneous processes are instantaneous, such as an explosion. Some are very slow, such as the rusting of an old car. ...
Mechanistic insights into pancreatic beta
... that GK is critical for beta-cell hyperplasia in response to insulin resistance. Recently, the effect of various GK activators including YH-GKA, Compound A, GKA50, and LY2121260 that trigger GK by binding to an allosteric site of the enzyme have been tested for their capacity to induce beta-cell pro ...
... that GK is critical for beta-cell hyperplasia in response to insulin resistance. Recently, the effect of various GK activators including YH-GKA, Compound A, GKA50, and LY2121260 that trigger GK by binding to an allosteric site of the enzyme have been tested for their capacity to induce beta-cell pro ...
Directions: Choose the BEST answer from among those given.
... 19. Anabolic reactions are the biosynthetic biochemical reactions or pathways in which larger molecules are made from smaller? a) true b) false 20. A-kinase (cyclic-AMP-dependent protein kinase) is an enzyme that phosphorylates target proteins in response to a rise in intracellular cyclic-AMP. This ...
... 19. Anabolic reactions are the biosynthetic biochemical reactions or pathways in which larger molecules are made from smaller? a) true b) false 20. A-kinase (cyclic-AMP-dependent protein kinase) is an enzyme that phosphorylates target proteins in response to a rise in intracellular cyclic-AMP. This ...
Characterisation and functional properties of watermelon (Citrullus
... solubility in the pH range 3–5 (data not shown). Protein solubility increased markedly below pH 3 and above pH 5. The considerable increase in protein solubility in acidic and alkaline environments was attributed to a gain in net negative or positive charge of proteins, with consequent interaction w ...
... solubility in the pH range 3–5 (data not shown). Protein solubility increased markedly below pH 3 and above pH 5. The considerable increase in protein solubility in acidic and alkaline environments was attributed to a gain in net negative or positive charge of proteins, with consequent interaction w ...
Analysis of metabolic pathways and fluxes in a newly discovered
... of C5 (e.g., xylose) and C6 sugars (e.g., glucose) and is tolerant to high ethanol concentrations (10%, v/v). We have investigated the central metabolism of this bacterium using both in vitro enzyme assays and 13C-based flux analysis to provide insights into the physiological properties of this extr ...
... of C5 (e.g., xylose) and C6 sugars (e.g., glucose) and is tolerant to high ethanol concentrations (10%, v/v). We have investigated the central metabolism of this bacterium using both in vitro enzyme assays and 13C-based flux analysis to provide insights into the physiological properties of this extr ...
Inherited Propionyl
... A B S T R A C T Cultured fibroblasts from a young girl with ketotic hyperglycinemia were unable to oxidize propionate-J'C to "CO2, but oxidized methylmalonate-"C and succinate-"C normally. This block in propionate catabolism was shown to result from a lack of propionylCoA carboxylase activity. The c ...
... A B S T R A C T Cultured fibroblasts from a young girl with ketotic hyperglycinemia were unable to oxidize propionate-J'C to "CO2, but oxidized methylmalonate-"C and succinate-"C normally. This block in propionate catabolism was shown to result from a lack of propionylCoA carboxylase activity. The c ...
Aspartic acid or Glutamic Acid Histidine
... 8. (8 pts) Please answer one of the following three choices. Be sure to indicate your choice. Choice A: Briefly describe the major thermodynamic factor that destabilizes the native (folded) state of a protein. Use an equation if appropriate. Choice B: Explain what thermodynamic factor(s) are respons ...
... 8. (8 pts) Please answer one of the following three choices. Be sure to indicate your choice. Choice A: Briefly describe the major thermodynamic factor that destabilizes the native (folded) state of a protein. Use an equation if appropriate. Choice B: Explain what thermodynamic factor(s) are respons ...
U.S. WHEY PROTEINS IN READY-TO-DRINK BEVERAGES
... isolates (containing 90-92% protein), or whey peptides, which provide distinct nutritional and functional advantages. In some cases, whey proteins are combined with other proteins such as vegetableor casein-based ingredients to create a particular overall amino acid composition or textural character ...
... isolates (containing 90-92% protein), or whey peptides, which provide distinct nutritional and functional advantages. In some cases, whey proteins are combined with other proteins such as vegetableor casein-based ingredients to create a particular overall amino acid composition or textural character ...
us whey proteins in ready-to-drink beverages
... isolates (containing 90-92% protein), or whey peptides, which provide distinct nutritional and functional advantages. In some cases, whey proteins are combined with other proteins such as vegetableor casein-based ingredients to create a particular overall amino acid composition or textural character ...
... isolates (containing 90-92% protein), or whey peptides, which provide distinct nutritional and functional advantages. In some cases, whey proteins are combined with other proteins such as vegetableor casein-based ingredients to create a particular overall amino acid composition or textural character ...
Protein Detection Methods in Proteomics Research
... The selection of the appropriate protein detection method is highly important, because the proteomics approach measures quantitative changes in expression levels in biological samples. A number of very different techniques exist. Ideally the detection limit should be as low as possible with an optim ...
... The selection of the appropriate protein detection method is highly important, because the proteomics approach measures quantitative changes in expression levels in biological samples. A number of very different techniques exist. Ideally the detection limit should be as low as possible with an optim ...
Protein Measurement with the Folin Phenol Reagent
... It is unnecessary to bring all the samples and standards to the same volume before the addition of the alkaline copper reagent, provided corThe critical volrections are made for small differences in final volume. umes are those of the alkaline copper and Folin reagents. If the protein is present in ...
... It is unnecessary to bring all the samples and standards to the same volume before the addition of the alkaline copper reagent, provided corThe critical volrections are made for small differences in final volume. umes are those of the alkaline copper and Folin reagents. If the protein is present in ...
Transforming Growth Factor- Signaling Strength Determines Target
... TR-II molecules and a single TGF dimer (see [2] for review). Once this ternary complex forms, the TR-II kinase activates the TR-I serine-threonine kinase. In most cell types, this is the key step in transducing all of TGF signals, thus positioning TR-I as the gatekeeper of the TGF signaling p ...
... TR-II molecules and a single TGF dimer (see [2] for review). Once this ternary complex forms, the TR-II kinase activates the TR-I serine-threonine kinase. In most cell types, this is the key step in transducing all of TGF signals, thus positioning TR-I as the gatekeeper of the TGF signaling p ...
review on enhancement of glucose uptake and up
... expression for prolong time leads to diabetes mellitus. Medicinal plants used in traditional treatments confirm a possibility of tackling diabetes by regulating the GLUT activity in the body, with lesser side effects. Resistant of tissues to insulin is a major manifestation in type 2, and the cause ...
... expression for prolong time leads to diabetes mellitus. Medicinal plants used in traditional treatments confirm a possibility of tackling diabetes by regulating the GLUT activity in the body, with lesser side effects. Resistant of tissues to insulin is a major manifestation in type 2, and the cause ...
Paracrine signalling

Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.