![Chemical Basis of Life](http://s1.studyres.com/store/data/000714850_1-978e2483bc8c1b3ffdd40372d245565f-300x300.png)
Chemical Basis of Life
... Proteins Chains of amino acids joined by peptide bonds 20 different types (alphabet) Peptide, polypeptides, and proteins (words) are all slightly different Structural levels Primary (1°) – sequence of amino acids Secondary (2°) – primary level folds to form alpha (α) – helixes and beta ...
... Proteins Chains of amino acids joined by peptide bonds 20 different types (alphabet) Peptide, polypeptides, and proteins (words) are all slightly different Structural levels Primary (1°) – sequence of amino acids Secondary (2°) – primary level folds to form alpha (α) – helixes and beta ...
Proteins POSTER ppt
... Structure is more conserved than sequence: functionally important sites resist changes due to selective advantage, whereas scaffold residues can accommodate changes. ...
... Structure is more conserved than sequence: functionally important sites resist changes due to selective advantage, whereas scaffold residues can accommodate changes. ...
Anti-CD30 human IL-2 fusion proteins display strong and specific
... decades, patients suffer from high toxicity of current therapeutic regimens. Since CD30 expression is very restricted, CD30-positive tumors are well suited for immunotherapeutic approaches. Several distinct immunotherapeutic approaches with chimeric, humanized, and bispecific antibodies as well as i ...
... decades, patients suffer from high toxicity of current therapeutic regimens. Since CD30 expression is very restricted, CD30-positive tumors are well suited for immunotherapeutic approaches. Several distinct immunotherapeutic approaches with chimeric, humanized, and bispecific antibodies as well as i ...
C h e m g u id e –... PROTEINS: STRUCTURE
... This diagram (also modified from the Chemguide page) shows some of the bits of the protein chain in the spirals. d) What name is given to the spirals? e) Name the intermolecular forces holding the spiral together and mark them on the diagram. f) What is represented by the string-like sections of the ...
... This diagram (also modified from the Chemguide page) shows some of the bits of the protein chain in the spirals. d) What name is given to the spirals? e) Name the intermolecular forces holding the spiral together and mark them on the diagram. f) What is represented by the string-like sections of the ...
Ch. 5 Biochemistry
... Hydrophobic; H bonds in water exclude fats Carboxyl group = fatty acid Non-polar C-H bonds in fatty acid ‘tails’ Ester linkage: 3 fatty acids to 1 glycerol (dehydration formation) ...
... Hydrophobic; H bonds in water exclude fats Carboxyl group = fatty acid Non-polar C-H bonds in fatty acid ‘tails’ Ester linkage: 3 fatty acids to 1 glycerol (dehydration formation) ...
Protein Modeling
... The primary structure is the linear sequence of amino acids. What determines this sequence? Where in the cell are amino acids joined this way? ...
... The primary structure is the linear sequence of amino acids. What determines this sequence? Where in the cell are amino acids joined this way? ...
Chapter 3 Presentation: Macromolecules
... by H-bonds. • The β-pleated sheet forms when 2 polypeptides are aligned side by side and hydrogen bond along their lengths. ...
... by H-bonds. • The β-pleated sheet forms when 2 polypeptides are aligned side by side and hydrogen bond along their lengths. ...
Amino acids, peptides and proteins
... interactions and in their electrophoretic separation. Proteins can also be separated on the basis of their size. The tertiary structure of proteins can be destroyed by denaturation. Finally, it is shown that even small peptides can possess biological activity, for example as hormones and transmitter ...
... interactions and in their electrophoretic separation. Proteins can also be separated on the basis of their size. The tertiary structure of proteins can be destroyed by denaturation. Finally, it is shown that even small peptides can possess biological activity, for example as hormones and transmitter ...
Functional Groups and Macromolecules
... environment and the internal part of the cell – The hydrophobic tails band in the center of the bilayer ...
... environment and the internal part of the cell – The hydrophobic tails band in the center of the bilayer ...
Name___________________________ How are elements and
... A) fatty acids B) carbohydrates C) oils D) amino acids ...
... A) fatty acids B) carbohydrates C) oils D) amino acids ...
Metastasis, the malignant stage in cancer development is
... Changes in sugar metabolism are well documented in diabetes, neurodegenerative, and cancer diseases. This phenomenon is conjugated to impaired protein glycosylation. It has been reported recently that the unique -N-acetyl glucose amine proteins modification is altered in diabetes and Alzheimer dise ...
... Changes in sugar metabolism are well documented in diabetes, neurodegenerative, and cancer diseases. This phenomenon is conjugated to impaired protein glycosylation. It has been reported recently that the unique -N-acetyl glucose amine proteins modification is altered in diabetes and Alzheimer dise ...
COMMON SUBSTANCES ESSENTIAL TO LIVING THINGS
... selenium deficiency in humans can be linked to cancer and heart disease. ¢ Selenium, along with vitamin E, helps protect cell membranes from damage caused by hydrogen peroxide, a poison that is produced by some chemical reactions in cells. ...
... selenium deficiency in humans can be linked to cancer and heart disease. ¢ Selenium, along with vitamin E, helps protect cell membranes from damage caused by hydrogen peroxide, a poison that is produced by some chemical reactions in cells. ...
MacroMolecules
... Macromolecules • Built from small organic compounds by linking a lot of chains ...
... Macromolecules • Built from small organic compounds by linking a lot of chains ...
7.2.A1 The promoter as an example of non
... operator. RNA polymerase binds to the _____________ allowing the genes that produce proteins involved in lactose metabolism ___________ be transcribed. ...
... operator. RNA polymerase binds to the _____________ allowing the genes that produce proteins involved in lactose metabolism ___________ be transcribed. ...
Ser-Ala-Trp
... C. The bond between the carbon atom and the peptide nitrogen atom is not free to rotate. D. The secondary structure affects the strength of the peptide unit. E. There is a large degree of freedom of rotation on either side of the peptide unit. ...
... C. The bond between the carbon atom and the peptide nitrogen atom is not free to rotate. D. The secondary structure affects the strength of the peptide unit. E. There is a large degree of freedom of rotation on either side of the peptide unit. ...
Protein Notes
... The elements C, H, O & N make up amino acids (AA) that are the building blocks (or mononmers)of PROTEIN. Proteins are organic molecules Proteins are macromolecules that contain many atoms. A single protein molecule may contain 10 or more AA linked in peptide chains/bonds Proteins are macron ...
... The elements C, H, O & N make up amino acids (AA) that are the building blocks (or mononmers)of PROTEIN. Proteins are organic molecules Proteins are macromolecules that contain many atoms. A single protein molecule may contain 10 or more AA linked in peptide chains/bonds Proteins are macron ...
Peptide Bonds - Newcastle University
... Two amino acids joined together are called a dipeptide. The condensation reaction you have just seen can repeat so any more amino acids can add together in the same way, forming a long chain called a polypeptide. For each protein, the order of amino acid residues is specific and different – it is th ...
... Two amino acids joined together are called a dipeptide. The condensation reaction you have just seen can repeat so any more amino acids can add together in the same way, forming a long chain called a polypeptide. For each protein, the order of amino acid residues is specific and different – it is th ...
Biochemistry notes (updated 10/13)
... Parts of the polypeptide coil or fold into local patterns. ...
... Parts of the polypeptide coil or fold into local patterns. ...
Bioinformatics how to predict protein structure using comparative
... use publicly available free tools to predict protein structure by comparative modeling ...
... use publicly available free tools to predict protein structure by comparative modeling ...
Organic Compounds: Carbohydrates
... Appear most often in body structures, important in binding structures together and in providing strength to certain body tissues, very stable Ex. - Collagen – found in bones, cartilage, and tendons-most abundant protein in body ex. Keratin – found in hair, nails, and makes the ...
... Appear most often in body structures, important in binding structures together and in providing strength to certain body tissues, very stable Ex. - Collagen – found in bones, cartilage, and tendons-most abundant protein in body ex. Keratin – found in hair, nails, and makes the ...
CHAPTER 2 FUNDAMENTAL CHEMISTRY FOR MICROBIOLOGY
... fats, phospholipids, and steroids. • They are relatively insoluble in water which makes them very useful as elements of cellular structure. • Some lipids contain more energy than carbohydrates but are harder to break down. ...
... fats, phospholipids, and steroids. • They are relatively insoluble in water which makes them very useful as elements of cellular structure. • Some lipids contain more energy than carbohydrates but are harder to break down. ...
Ch 2 - Biochemistry
... INORGANIC COMPOUNDS lack carbon (with the exception of carbon dioxide) and tend to be simple, small molecules water, salts, most acids and bases ...
... INORGANIC COMPOUNDS lack carbon (with the exception of carbon dioxide) and tend to be simple, small molecules water, salts, most acids and bases ...
Cyclol
![](https://commons.wikimedia.org/wiki/Special:FilePath/Cyclol_reaction.png?width=300)
The cyclol hypothesis is the first structural model of a folded, globular protein. It was developed by Dorothy Wrinch in the late 1930s, and was based on three assumptions. Firstly, the hypothesis assumes that two peptide groups can be crosslinked by a cyclol reaction (Figure 1); these crosslinks are covalent analogs of non-covalent hydrogen bonds between peptide groups. These reactions have been observed in the ergopeptides and other compounds. Secondly, it assumes that, under some conditions, amino acids will naturally make the maximum possible number of cyclol crosslinks, resulting in cyclol molecules (Figure 2) and cyclol fabrics (Figure 3). These cyclol molecules and fabrics have never been observed. Finally, the hypothesis assumes that globular proteins have a tertiary structure corresponding to Platonic solids and semiregular polyhedra formed of cyclol fabrics with no free edges. Such ""closed cyclol"" molecules have not been observed either.Although later data demonstrated that this original model for the structure of globular proteins needed to be amended, several elements of the cyclol model were verified, such as the cyclol reaction itself and the hypothesis that hydrophobic interactions are chiefly responsible for protein folding. The cyclol hypothesis stimulated many scientists to research questions in protein structure and chemistry, and was a precursor of the more accurate models hypothesized for the DNA double helix and protein secondary structure. The proposal and testing of the cyclol model also provides an excellent illustration of empirical falsifiability acting as part of the scientific method.