Modified from Carley Karsten Lecture 8
... a. primary: amino acid sequence. determined by covalent (peptide) bonds between amino acids. b. secondary: coils and folds. determined by hydrogen bonds between amino and carboxy groups in the backbone. c. tertiary: complex folding. determined by all kinds of bonding between any of the different R g ...
... a. primary: amino acid sequence. determined by covalent (peptide) bonds between amino acids. b. secondary: coils and folds. determined by hydrogen bonds between amino and carboxy groups in the backbone. c. tertiary: complex folding. determined by all kinds of bonding between any of the different R g ...
Enzymes and proteins - Hochschule Biberach
... reverse turn, domains), X-ray diffraction analysis, interaction between protein side chains • Non-protein structure components (glycosylation, phosphate groups, N-terminal acyl residues) • Enzyme screening and protein engineering (rational design, directed evolution, saturated mutagenesis (CAST, B-F ...
... reverse turn, domains), X-ray diffraction analysis, interaction between protein side chains • Non-protein structure components (glycosylation, phosphate groups, N-terminal acyl residues) • Enzyme screening and protein engineering (rational design, directed evolution, saturated mutagenesis (CAST, B-F ...
Denaturation of proteins
... tertiary structure and, if applicable, quaternary structure) and how those forces would be affected by the changes in temperature or pH. For example, H bonds, such as in C=O∙∙∙∙H-N, are important in 2°, 3°, and 4° structure. As the temperature of a solution containing the protein is raised, the extr ...
... tertiary structure and, if applicable, quaternary structure) and how those forces would be affected by the changes in temperature or pH. For example, H bonds, such as in C=O∙∙∙∙H-N, are important in 2°, 3°, and 4° structure. As the temperature of a solution containing the protein is raised, the extr ...
Chapter 1_summary notes
... polar molecules or ions (e.g. Na+, NO3- etc). Polar substances can form H bonds with polar molecules of water and so dissolve – they are called hydrophilic (water loving) Non-polar substances will not dissolve in water because they cannot form H bonds with water – they are hydrophobic. Rule for subs ...
... polar molecules or ions (e.g. Na+, NO3- etc). Polar substances can form H bonds with polar molecules of water and so dissolve – they are called hydrophilic (water loving) Non-polar substances will not dissolve in water because they cannot form H bonds with water – they are hydrophobic. Rule for subs ...
Ecole Doctorale des Sciences Chimiques ED250 - FrenchBIC
... their CV, a motivation letter, and the name of two reference persons. Important: Selected candidates will be interviewed the 15th or 16th of May by the Doctoral School Committee in Marseille (or by visioconference). Proposal summary: Giant viruses were discovered about more than a decade ago (1). Th ...
... their CV, a motivation letter, and the name of two reference persons. Important: Selected candidates will be interviewed the 15th or 16th of May by the Doctoral School Committee in Marseille (or by visioconference). Proposal summary: Giant viruses were discovered about more than a decade ago (1). Th ...
Molecules of Life Additional Notes
... acids form a covalent bond, called a PEPTIDE BOND. 9. Amino acids can bond to each other one at a time, forming a long chain called a POLYPEPTIDE. 10. Proteins are composed of one or more polypeptides. Some proteins are very large molecules, containing hundreds of amino acids. 11. One group of prote ...
... acids form a covalent bond, called a PEPTIDE BOND. 9. Amino acids can bond to each other one at a time, forming a long chain called a POLYPEPTIDE. 10. Proteins are composed of one or more polypeptides. Some proteins are very large molecules, containing hundreds of amino acids. 11. One group of prote ...
Survey
... stains, different post-transfer steps to determine the best transfer conditions. l) How about naturally occuring PTM's to add onto previous two year's studies. Quantitation of PTM. Example, naturally occuring histone with a free N-terminus. m) Recently there was a discussion on the ABRF list concern ...
... stains, different post-transfer steps to determine the best transfer conditions. l) How about naturally occuring PTM's to add onto previous two year's studies. Quantitation of PTM. Example, naturally occuring histone with a free N-terminus. m) Recently there was a discussion on the ABRF list concern ...
Making Proteins - Foothill Technology High School
... Made up of Carbon, Hydrogen, Oxygen and Nitrogen (and some Sulfur) Proteins are responsible for many ...
... Made up of Carbon, Hydrogen, Oxygen and Nitrogen (and some Sulfur) Proteins are responsible for many ...
AP chemistry & organic compounds
... – In a nonpolar covalent bond, atoms share the electrons equally; one atom does not attract the shared electrons more strongly than the other atom ...
... – In a nonpolar covalent bond, atoms share the electrons equally; one atom does not attract the shared electrons more strongly than the other atom ...
1 - Rosshall Academy
... State that proteins are the major structural materials of animal tissue and are involved in the maintenance and regulation of life processes and include enzymes, many hormones eg, insulin and haemoglobin. ...
... State that proteins are the major structural materials of animal tissue and are involved in the maintenance and regulation of life processes and include enzymes, many hormones eg, insulin and haemoglobin. ...
CH 5: Carbs, Lipids, Proteins, and Nucleic Acids – Study Chart I
... Directions: Use your textbook, class notes, and/or internet resources to complete the charts below. In the “box” to the right of each molecule, write a brief description explaining what the molecule is, or does, or is used for, in living things. ...
... Directions: Use your textbook, class notes, and/or internet resources to complete the charts below. In the “box” to the right of each molecule, write a brief description explaining what the molecule is, or does, or is used for, in living things. ...
Protein Synthesis
... and arranged into amino acid sequences. tRNA (transfer RNA) carries amino acids to the ribosomes where they join together to form proteins rRNA (ribosomal RNA) is part of the structure of ...
... and arranged into amino acid sequences. tRNA (transfer RNA) carries amino acids to the ribosomes where they join together to form proteins rRNA (ribosomal RNA) is part of the structure of ...
Figure 20-5. Common intracellular signaling proteins.
... signaling proteins. (a) GTP-binding proteins with GTPase activity function as molecular switches. When bound to GTP they are active; when bound to GDP, they are inactive. They fall into two categories, trimeric G proteins and Ras-like proteins(b) Protein kinases modulate the activity or the binding ...
... signaling proteins. (a) GTP-binding proteins with GTPase activity function as molecular switches. When bound to GTP they are active; when bound to GDP, they are inactive. They fall into two categories, trimeric G proteins and Ras-like proteins(b) Protein kinases modulate the activity or the binding ...
Lecture 1 - Department of Biological Sciences
... QuickTime™ and a MPEG-4 Video decompressor are needed to see this picture. ...
... QuickTime™ and a MPEG-4 Video decompressor are needed to see this picture. ...
Organic Molecules
... • The starch found in whole grains and vegetables is a complex carbohydrate made of chains of simpler glucose molecules. • Our body contains enzymes which breaks down carbohydrates in the food you eat into glucose, which your cells can use as energy. ...
... • The starch found in whole grains and vegetables is a complex carbohydrate made of chains of simpler glucose molecules. • Our body contains enzymes which breaks down carbohydrates in the food you eat into glucose, which your cells can use as energy. ...
HomeworkCh_15,16Answers
... 1. Plants do not eat but do require CO2, H2O, and sunlight to live. How is this different from animals? What system do plants have to allow for their simple needs? Animals require nutrients such as carbohydrates, proteins and lipids to survive. Photosynthesis. 2. What substances constitute the macro ...
... 1. Plants do not eat but do require CO2, H2O, and sunlight to live. How is this different from animals? What system do plants have to allow for their simple needs? Animals require nutrients such as carbohydrates, proteins and lipids to survive. Photosynthesis. 2. What substances constitute the macro ...
Power Point Presentation
... atoms and molecules into a useful product or copies of itself. One nano assembler working atom by atom would be rather slow because most desirable products (baseballs, cars, and the like) are made of trillions and trillions of atoms. However, such an assembler robot arm could makes copies of itself ...
... atoms and molecules into a useful product or copies of itself. One nano assembler working atom by atom would be rather slow because most desirable products (baseballs, cars, and the like) are made of trillions and trillions of atoms. However, such an assembler robot arm could makes copies of itself ...
Introduction to Proteins: Biotech 2
... cheap, proteins not expressed properly Mammalian Cell Systems – finicky, grow slowly, and expensive, BUT processes human proteins correctly ...
... cheap, proteins not expressed properly Mammalian Cell Systems – finicky, grow slowly, and expensive, BUT processes human proteins correctly ...
Vragen voor tentamen Protein Engineering (8S080)
... binding domain. The ligand binding domain (LBD) contains a binding site for estrogen. The activity of nuclear receptors is known to be regulated by post translational modifications such as acetylation of lysines and phosphorylation of serines and tyrosines. The LBD (aa 280-502) can be recombinantly ...
... binding domain. The ligand binding domain (LBD) contains a binding site for estrogen. The activity of nuclear receptors is known to be regulated by post translational modifications such as acetylation of lysines and phosphorylation of serines and tyrosines. The LBD (aa 280-502) can be recombinantly ...
2016 N1 Week 4
... Warm UP Identify the following properties as either a carbohydrate or a lipid: 1. Does not dissolve in water. 2. The monomer is monosaccharide. 3. This molecule is not a true polymer. 4. The ratio of hydrogen to oxygen is 2:1. 5. Identify the following as a carb or lipid. B A ...
... Warm UP Identify the following properties as either a carbohydrate or a lipid: 1. Does not dissolve in water. 2. The monomer is monosaccharide. 3. This molecule is not a true polymer. 4. The ratio of hydrogen to oxygen is 2:1. 5. Identify the following as a carb or lipid. B A ...
Cyclol
The cyclol hypothesis is the first structural model of a folded, globular protein. It was developed by Dorothy Wrinch in the late 1930s, and was based on three assumptions. Firstly, the hypothesis assumes that two peptide groups can be crosslinked by a cyclol reaction (Figure 1); these crosslinks are covalent analogs of non-covalent hydrogen bonds between peptide groups. These reactions have been observed in the ergopeptides and other compounds. Secondly, it assumes that, under some conditions, amino acids will naturally make the maximum possible number of cyclol crosslinks, resulting in cyclol molecules (Figure 2) and cyclol fabrics (Figure 3). These cyclol molecules and fabrics have never been observed. Finally, the hypothesis assumes that globular proteins have a tertiary structure corresponding to Platonic solids and semiregular polyhedra formed of cyclol fabrics with no free edges. Such ""closed cyclol"" molecules have not been observed either.Although later data demonstrated that this original model for the structure of globular proteins needed to be amended, several elements of the cyclol model were verified, such as the cyclol reaction itself and the hypothesis that hydrophobic interactions are chiefly responsible for protein folding. The cyclol hypothesis stimulated many scientists to research questions in protein structure and chemistry, and was a precursor of the more accurate models hypothesized for the DNA double helix and protein secondary structure. The proposal and testing of the cyclol model also provides an excellent illustration of empirical falsifiability acting as part of the scientific method.