BICH/GENE 431 KNOWLEDGE OBJECTIVES Chapter 9 – Mutations
... - reactive oxygen species (hydrogen peroxide, hydroxide radicals); common product is oxoG UV light causes pyrimidine dimers, such as thymine dimers Ionizing radiation (x rays, gamma rays) cause ds DNA breaks Bleomycin (anti cancer drug) causes ds breaks Base analogs – what are they? A common example ...
... - reactive oxygen species (hydrogen peroxide, hydroxide radicals); common product is oxoG UV light causes pyrimidine dimers, such as thymine dimers Ionizing radiation (x rays, gamma rays) cause ds DNA breaks Bleomycin (anti cancer drug) causes ds breaks Base analogs – what are they? A common example ...
Who are you? This question can be answered many ways…
... work exactly as it is supposed to? • Genetic Disorders – Genetic Disorders result when there is a change in your genes that changes the way your body functions. – Sometimes the change can be so large that your body cannot function. ...
... work exactly as it is supposed to? • Genetic Disorders – Genetic Disorders result when there is a change in your genes that changes the way your body functions. – Sometimes the change can be so large that your body cannot function. ...
GENETICS
... characteristics and others) These are homologous since both members of the pair are usually identical in shape and size The position a gene occupies on a chromosome is called a LOCUS There are different loci for colour, height, etc. Genes that occupy corresponding loci are called ...
... characteristics and others) These are homologous since both members of the pair are usually identical in shape and size The position a gene occupies on a chromosome is called a LOCUS There are different loci for colour, height, etc. Genes that occupy corresponding loci are called ...
word
... What kinds of bonds are required for creating macromolecules? What is the bond type between two amino acids joined in a polypeptide or protein What is the bond type between two sugars in an oligosaccharide What is the bond type between two nucleotides in a polynucleotide What is cellulose considered ...
... What kinds of bonds are required for creating macromolecules? What is the bond type between two amino acids joined in a polypeptide or protein What is the bond type between two sugars in an oligosaccharide What is the bond type between two nucleotides in a polynucleotide What is cellulose considered ...
Name: ____________ Pd.: ______ Date: plasmid genetic
... 43. A strand of DNA formed by the splicing of DNA from two different species is called ____recombinant_____ DNA. 44. DNA ______fingerprinting__________ has been used in criminal investigations because DNA analysis is believed to allow investigators to distinguish body cells of different individuals, ...
... 43. A strand of DNA formed by the splicing of DNA from two different species is called ____recombinant_____ DNA. 44. DNA ______fingerprinting__________ has been used in criminal investigations because DNA analysis is believed to allow investigators to distinguish body cells of different individuals, ...
Cut-and-paste DNA: fixing mutations with `genome editing`
... thymine - abbreviated as A, C, G and T. Normally, near one end of the huntingtin gene, there’s a stretch of 17 or so repeated C-A-G bases. In people with HD, the normal C-A-G stretch is longer, due to a kind of genetic stutter. That’s the ‘triplet repeat expansion’ that causes HD. Genes are the blue ...
... thymine - abbreviated as A, C, G and T. Normally, near one end of the huntingtin gene, there’s a stretch of 17 or so repeated C-A-G bases. In people with HD, the normal C-A-G stretch is longer, due to a kind of genetic stutter. That’s the ‘triplet repeat expansion’ that causes HD. Genes are the blue ...
Gene Section WHSC1L1 (Wolf-Hirschhorn syndrome candidate 1 like gene 1)
... subset of breast cancers (but it remains to be determined which gene, within an amplicon, is the critical gene). ...
... subset of breast cancers (but it remains to be determined which gene, within an amplicon, is the critical gene). ...
Color Blindness
... The normal human retina contains two kinds of light sensitive cells: the rod cells (active only in low light) and the cone cells (active in normal daylight and responsible for color perception). Normally, there are three kinds of cones (each one sensitive to a specific range of wavelengths): "red" ...
... The normal human retina contains two kinds of light sensitive cells: the rod cells (active only in low light) and the cone cells (active in normal daylight and responsible for color perception). Normally, there are three kinds of cones (each one sensitive to a specific range of wavelengths): "red" ...
Oct 23, 2006 Handout
... a. If it is in a non-coding region, usually nothing. If it is in a coding region it will cause a frameshift: because codons are made of three nucleotides, deleting one base pair disrupts the “reading frame” or division of the sequence into threes. Frameshifts occur if the number of base pairs insert ...
... a. If it is in a non-coding region, usually nothing. If it is in a coding region it will cause a frameshift: because codons are made of three nucleotides, deleting one base pair disrupts the “reading frame” or division of the sequence into threes. Frameshifts occur if the number of base pairs insert ...
DNA Webquest - Jackson School District
... 3. Franklin worked with Raymond Gosling and was able to get photos of DNA fibers. What did she conclude from these photos (two things)? ______________________________________________________________________________ ______________________________________________________________________________ Go to ...
... 3. Franklin worked with Raymond Gosling and was able to get photos of DNA fibers. What did she conclude from these photos (two things)? ______________________________________________________________________________ ______________________________________________________________________________ Go to ...
A Frameshift Mutation Leading to Type 1
... molecular and genetic levels, and in each case the variant has been produced by a single base substitution leading to an amino acid change that interferes with the binding of ATIII to heparin or its interaction with t h r o m b h 8 Although type 1 deficiencies are much more common, the molecular bas ...
... molecular and genetic levels, and in each case the variant has been produced by a single base substitution leading to an amino acid change that interferes with the binding of ATIII to heparin or its interaction with t h r o m b h 8 Although type 1 deficiencies are much more common, the molecular bas ...
TB1 - BIOCHEM, Bidichandani, Genetic Diseases
... obstructive azoospermia. Meconium ileus (Intestinal obstruction in the fetus and newborn followed by inspisitation of meconium) is present in 10-20% of patients. CFTR (cystic fibrosis transmembrane conductance regulator) is the gene that is mutated to lead to the disease. It was the first to be ide ...
... obstructive azoospermia. Meconium ileus (Intestinal obstruction in the fetus and newborn followed by inspisitation of meconium) is present in 10-20% of patients. CFTR (cystic fibrosis transmembrane conductance regulator) is the gene that is mutated to lead to the disease. It was the first to be ide ...
Semester 2 – Final Exam Review2016
... 11. What is a mutation? How is a point mutation different from a chromosomal mutation? Chapter 16: 1. What is the definition of evolution? ...
... 11. What is a mutation? How is a point mutation different from a chromosomal mutation? Chapter 16: 1. What is the definition of evolution? ...
cell Communicaiton and Division Review
... 1. Explain the differences between eukaryotic cell division and binary fission. 2. Define the following words: chromosome, chromatin, chromatid, centriole, cytokinesis, centromere, and kinetochore. 3. Explain the checkpoints in the cell cycle. 4. Explain the rolls of cyclin, MFP protein complex, pro ...
... 1. Explain the differences between eukaryotic cell division and binary fission. 2. Define the following words: chromosome, chromatin, chromatid, centriole, cytokinesis, centromere, and kinetochore. 3. Explain the checkpoints in the cell cycle. 4. Explain the rolls of cyclin, MFP protein complex, pro ...
47. Genetic Disorders
... Sickle-Cell Anemia – red blood cells become half-moon, or sickleshaped; because of this unusual shape, the red blood cells cannot carry as much oxygen (leading to fatigue) and can block blood vessels (which can lead to lung and heart damage and stroke). Sickle-cell anemia is caused by a co-dominant ...
... Sickle-Cell Anemia – red blood cells become half-moon, or sickleshaped; because of this unusual shape, the red blood cells cannot carry as much oxygen (leading to fatigue) and can block blood vessels (which can lead to lung and heart damage and stroke). Sickle-cell anemia is caused by a co-dominant ...
SB2a Build DNA using the Nucleotides Then Print
... when you made RNA? Where does DNA Replication take place? Where does transcription take place in a cell? ...
... when you made RNA? Where does DNA Replication take place? Where does transcription take place in a cell? ...
Jeffreys - OldForensics 2012-2013
... techniques those of which are commonly used today for police and detective work, paternity tests, and immigration issues ...
... techniques those of which are commonly used today for police and detective work, paternity tests, and immigration issues ...
Lecture 32 Slides
... if functional domain is duplicated --> functional enhancement -complete gene gene dosage enhanced New function can evolve due to relaxed selection on one copy ...
... if functional domain is duplicated --> functional enhancement -complete gene gene dosage enhanced New function can evolve due to relaxed selection on one copy ...
Chapter 6
... protein (with its twenty-letter alphabet of amino acids). Each amino acid has a central carbon atom (Figure 6.10) flanked by an amino group (NH2) and a carboxyl group (COOH); one of twenty possible side chains is also attached to the central carbon. Ribosomes, with tRNA (Figure 6.9), decode the mess ...
... protein (with its twenty-letter alphabet of amino acids). Each amino acid has a central carbon atom (Figure 6.10) flanked by an amino group (NH2) and a carboxyl group (COOH); one of twenty possible side chains is also attached to the central carbon. Ribosomes, with tRNA (Figure 6.9), decode the mess ...
Translation and the Genetic Code
... 11. During translation, stop codons code for the amino acid tyrosine which is always the last amino acid in a polypeptide chain. (T/F) 12. The genetic code is redundant, meaning that most amino acids are specified by more than one codon. (T/F) ...
... 11. During translation, stop codons code for the amino acid tyrosine which is always the last amino acid in a polypeptide chain. (T/F) 12. The genetic code is redundant, meaning that most amino acids are specified by more than one codon. (T/F) ...
Transcription and Translation
... 1. mRNA binds the small subunit of the ribosome 2. tRNA molecules are present, each one carrying the specific aa & anticodon 3. tRNA binds to the ribosome at the site where the anticodon matches the codon on the mRNA 4. Two tRNAs binds at once and the first one in transfers the growing polypeptide c ...
... 1. mRNA binds the small subunit of the ribosome 2. tRNA molecules are present, each one carrying the specific aa & anticodon 3. tRNA binds to the ribosome at the site where the anticodon matches the codon on the mRNA 4. Two tRNAs binds at once and the first one in transfers the growing polypeptide c ...
ch14_sec1 NOTES
... • DNA and chromosomes are involved in many processes, so there are many kinds of mutations. • Most mutations involve a misplacement of a nucleotide in a DNA segment. • A mutation may change the results of a gene (when the gene is translated and transcribed), but not all mutations ...
... • DNA and chromosomes are involved in many processes, so there are many kinds of mutations. • Most mutations involve a misplacement of a nucleotide in a DNA segment. • A mutation may change the results of a gene (when the gene is translated and transcribed), but not all mutations ...
Pierce chapter 10
... nucleotides may be complementary and pair – forming doublestranded regions • Hairpin – Region of complementary bases form base; loop formed by unpaired bases in the middle ...
... nucleotides may be complementary and pair – forming doublestranded regions • Hairpin – Region of complementary bases form base; loop formed by unpaired bases in the middle ...
Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.