BIAXIN® Filmtab® (clarithromycin tablets, USP) BIAXIN
... Clarithromycin has demonstrated in vitro activity against Mycobacterium avium complex (MAC) microorganisms isolated from both AIDS and non-AIDS patients. While gene probe techniques may be used to distinguish M. avium species from M. intracellulare, many studies only reported results on M. avium com ...
... Clarithromycin has demonstrated in vitro activity against Mycobacterium avium complex (MAC) microorganisms isolated from both AIDS and non-AIDS patients. While gene probe techniques may be used to distinguish M. avium species from M. intracellulare, many studies only reported results on M. avium com ...
The Placebo Effect (A comprehensive Review of the Placebo Effect
... that would have happened regardless of the intervention. Another example is regression to the mean, a statistical phenomenon that assumes that in a given population, extremes in reported pain intensity will change over time toward the average of that population. In the case of pain, this phenomenon ...
... that would have happened regardless of the intervention. Another example is regression to the mean, a statistical phenomenon that assumes that in a given population, extremes in reported pain intensity will change over time toward the average of that population. In the case of pain, this phenomenon ...
A tale of two stories: astrocyte regulation of
... astrocytes – the main type of glial cells in the hippocampus and the cortex [16-18] – together with the discovery of two-way astrocyte-neuron communication [19, 20], suggest an active role of these cells in modulation of synaptic transmission and information processing in the brain ...
... astrocytes – the main type of glial cells in the hippocampus and the cortex [16-18] – together with the discovery of two-way astrocyte-neuron communication [19, 20], suggest an active role of these cells in modulation of synaptic transmission and information processing in the brain ...
Antibody–Drug Conjugates (ADCs) Derived from
... suitable for conjugation. Later studies revealed that subtle differences in the ADC microenvironments significantly affect linker stability, which correlates with improved efficacy.14 The combined results indicate that ADC activity is highly dependent upon the conjugation sites and suggest that optimal c ...
... suitable for conjugation. Later studies revealed that subtle differences in the ADC microenvironments significantly affect linker stability, which correlates with improved efficacy.14 The combined results indicate that ADC activity is highly dependent upon the conjugation sites and suggest that optimal c ...
Interaction of the Frontal Eye Field and Superior Colliculus for
... the hypothesis that two parallel pathways may control saccades to visual targets (Keating and Gooley 1988a,b; Keating et al. 1983; Schiller 1977; Schiller and Chou 1998; Schiller et al. 1980, 1987). One pathway goes directly from the FEF to the brain stem premotor circuitry, where saccades are ultim ...
... the hypothesis that two parallel pathways may control saccades to visual targets (Keating and Gooley 1988a,b; Keating et al. 1983; Schiller 1977; Schiller and Chou 1998; Schiller et al. 1980, 1987). One pathway goes directly from the FEF to the brain stem premotor circuitry, where saccades are ultim ...
Primary- and Secondary-Like Jaw-Muscle Spindle Afferents Have
... 6.5 mm). Jaw displacements of 2.5 mm then were produced via an electromagnetic vibrator attached to the jaw at the diastema and used as the search stimulus for stretch-sensitive afferents. Intraaxonal recordings made from afferents in this region of the brain stem whose firing frequency increased du ...
... 6.5 mm). Jaw displacements of 2.5 mm then were produced via an electromagnetic vibrator attached to the jaw at the diastema and used as the search stimulus for stretch-sensitive afferents. Intraaxonal recordings made from afferents in this region of the brain stem whose firing frequency increased du ...
attenuating trigeminal neuropathic pain by
... First of all, I have to thank my mentor, Dr. Karin Westlund High. Thank you for the funding that you have provided me for this project. Thank you also for allowing me freedom to research what I wanted. You trusted me and believed in my vision, so thank you. I admire your courage in life and respect ...
... First of all, I have to thank my mentor, Dr. Karin Westlund High. Thank you for the funding that you have provided me for this project. Thank you also for allowing me freedom to research what I wanted. You trusted me and believed in my vision, so thank you. I admire your courage in life and respect ...
Neuro-Opthalmology (Developments in Ophthalmology, Vol. 40)
... many ways [1]: they are responsive to different metabolic and neuromuscular diseases; their myosin retains some characteristics seen only in the early stages of the embryological development of skeletal muscles, and hence they contain different muscle fiber types than skeletal muscles. In many speci ...
... many ways [1]: they are responsive to different metabolic and neuromuscular diseases; their myosin retains some characteristics seen only in the early stages of the embryological development of skeletal muscles, and hence they contain different muscle fiber types than skeletal muscles. In many speci ...
PACIFIC BUSPIRONE Presentation NEW ZEALAND DATA SHEET
... Buspirone hydrochloride belongs chemically to the class of pharmacologic agents with selective anxiolytic psychotropic activity known as the azapirones. The mechanism of action of buspirone is unknown. In contrast to the benzodiazepines, and other anxiolytic agents, buspirone does not exert anticonv ...
... Buspirone hydrochloride belongs chemically to the class of pharmacologic agents with selective anxiolytic psychotropic activity known as the azapirones. The mechanism of action of buspirone is unknown. In contrast to the benzodiazepines, and other anxiolytic agents, buspirone does not exert anticonv ...
stimulant treatment history predicts frontal-striatal
... duration, and dose, vary substantially from one patient to the other. There have been reports suggesting that such individual differences with regard to treatment patterns may predict long-‐term outcomes (Dalsgaard et al., 2014; Mannuzza et al., 2008). ...
... duration, and dose, vary substantially from one patient to the other. There have been reports suggesting that such individual differences with regard to treatment patterns may predict long-‐term outcomes (Dalsgaard et al., 2014; Mannuzza et al., 2008). ...
Salvia Divinorum
... medical studies undertaken to examine the drug's physiological effects have focused only on short-term effects. However, information provided by abusers indicates that the negative longterm effects of Salvia Divinorum may be similar to those produced by other hallucinogens such as LSD (lysergic acid ...
... medical studies undertaken to examine the drug's physiological effects have focused only on short-term effects. However, information provided by abusers indicates that the negative longterm effects of Salvia Divinorum may be similar to those produced by other hallucinogens such as LSD (lysergic acid ...
Nicotine and the Central Nervous System
... observation has important implications for the management of nicotine dependence. Nicotine has been shown to be the psychoactive substance in cigarette smoke that accounts for both self-administration and reinforcement of drugtaking behavior. In one study, double-blind substitution of saline for nic ...
... observation has important implications for the management of nicotine dependence. Nicotine has been shown to be the psychoactive substance in cigarette smoke that accounts for both self-administration and reinforcement of drugtaking behavior. In one study, double-blind substitution of saline for nic ...
министерство здравоохранения республики беларусь
... e) the biotransformation of the drug in the liver. 40. Parameter that characterizes the «apparent volume of distribution». Variants of the answer: a) the rate of absorption of the drug; b) the rate of elimination of the drug; c) the decay rate of the drug; d) the efficacy of; e) the ability of the d ...
... e) the biotransformation of the drug in the liver. 40. Parameter that characterizes the «apparent volume of distribution». Variants of the answer: a) the rate of absorption of the drug; b) the rate of elimination of the drug; c) the decay rate of the drug; d) the efficacy of; e) the ability of the d ...
Acquisition of Nicotine Discrimination and Discriminative Stimulus
... Lee et al., 1987; Nikodijevićc et al., 1993) and rates of schedule-controlled responding (White, 1988; Goldberg et al., 1989; Newland and Brown, 1997; Jaszyna et al., 1998) followed by decreases as doses of the drugs increase. Moreover, both nicotine and caffeine can each serve as discriminative st ...
... Lee et al., 1987; Nikodijevićc et al., 1993) and rates of schedule-controlled responding (White, 1988; Goldberg et al., 1989; Newland and Brown, 1997; Jaszyna et al., 1998) followed by decreases as doses of the drugs increase. Moreover, both nicotine and caffeine can each serve as discriminative st ...
Altered Resting-State Functional Connectivity of
... (ACC), dorsomedial prefrontal cortex, and dorsal ACC than the trauma-exposed control group (po0.05; corrected). The trauma-exposed control group had stronger functional connectivity of the BLA complex with the left inferior frontal gyrus than the PTSD group (po0.05; corrected). The CMA complex lacke ...
... (ACC), dorsomedial prefrontal cortex, and dorsal ACC than the trauma-exposed control group (po0.05; corrected). The trauma-exposed control group had stronger functional connectivity of the BLA complex with the left inferior frontal gyrus than the PTSD group (po0.05; corrected). The CMA complex lacke ...
Platelet inhibitory activity and pharmacokinetics of prasugrel
... assessed using 5 and 20 mM ADP, was periodically measured over a 7-day period by light transmission aggregometry. Plasma concentrations for three major metabolites, R-95913, R-106583, and R-100932, were measured. There were no serious adverse events and no clinically significant changes noted in any ...
... assessed using 5 and 20 mM ADP, was periodically measured over a 7-day period by light transmission aggregometry. Plasma concentrations for three major metabolites, R-95913, R-106583, and R-100932, were measured. There were no serious adverse events and no clinically significant changes noted in any ...
1. Exposure Data - IARC Monographs
... more neoplasms were found in the drug-treated patients because subsequent thyroidectomy was more frequent in this group (30% of drug-treated patients, as compared with 0.5% of those initially treated with 131I and 1.2% of those treated with primary thyroidectomy), which provided more opportunity for ...
... more neoplasms were found in the drug-treated patients because subsequent thyroidectomy was more frequent in this group (30% of drug-treated patients, as compared with 0.5% of those initially treated with 131I and 1.2% of those treated with primary thyroidectomy), which provided more opportunity for ...
Analysis of submissions: Proposal to Classify
... The possibility of a legal market leading to the release of an increasing range of little understood psychoactive compounds; ...
... The possibility of a legal market leading to the release of an increasing range of little understood psychoactive compounds; ...
Greenway FL, Whitehouse MJ, Guttadauria M
... the United States, obesity accounts for several hundred thousand deaths annually and current obesity-related medical costs are estimated at more than $100 billion per year (5). Despite dramatic advances in our understanding of central regulation of energy balance and obesity, there are few approved ...
... the United States, obesity accounts for several hundred thousand deaths annually and current obesity-related medical costs are estimated at more than $100 billion per year (5). Despite dramatic advances in our understanding of central regulation of energy balance and obesity, there are few approved ...
ADHD: CT Studies
... • Dopamine depletion hypothesis (Shaywitz et al 1977) • lower levels of homovanillic acid (HVA), dopamine metabolite in CSF of ADHD compared to controls • Executive function impairments caused by hypofrontality secondary to structural, biochemical changes in prefrontal cortex • Genetic studies showi ...
... • Dopamine depletion hypothesis (Shaywitz et al 1977) • lower levels of homovanillic acid (HVA), dopamine metabolite in CSF of ADHD compared to controls • Executive function impairments caused by hypofrontality secondary to structural, biochemical changes in prefrontal cortex • Genetic studies showi ...
Neck Muscle Responses to Stimulation of Monkey Superior
... and 1,500 ms. SC stimulation (variable duration, described in the following text) was delivered on 80 –90% of all trials between 500 and 1,000 ms after the onset of fixation. Stimulation was delivered either while the FP remained visible (fixation trials; 40 – 45% of all trials) or 200 ms after the ...
... and 1,500 ms. SC stimulation (variable duration, described in the following text) was delivered on 80 –90% of all trials between 500 and 1,000 ms after the onset of fixation. Stimulation was delivered either while the FP remained visible (fixation trials; 40 – 45% of all trials) or 200 ms after the ...
Prokinetic agents: current aspects with focus on cisapride
... microcircuit.1 Cisapride also exerts an antagonistic action on 5-HT3 receptors. Originally researchers considered that the prokinetic action of cisapride could be justified by this action. Later they came to the conclusion that the pharmacological properties of cisapride may result from its agonisti ...
... microcircuit.1 Cisapride also exerts an antagonistic action on 5-HT3 receptors. Originally researchers considered that the prokinetic action of cisapride could be justified by this action. Later they came to the conclusion that the pharmacological properties of cisapride may result from its agonisti ...
34th ECDD 2006/5 gamma-hydroxybutyric acid (GHB)
... The analytical profile of GHB has been described in numerous papers. Early data pertaining to GC-MS and GC-FID are described [4-7]; analysis usually requires conversion to -butyrolactone (GBL) or chemical derivation. However, newer analytical methods have become available, which have increased sens ...
... The analytical profile of GHB has been described in numerous papers. Early data pertaining to GC-MS and GC-FID are described [4-7]; analysis usually requires conversion to -butyrolactone (GBL) or chemical derivation. However, newer analytical methods have become available, which have increased sens ...