By ON THE ROLE OF THE SUPERIOR COLLICULUS IN THE CONTROL... VISUALLY-GUIDED SACCADES
... and saccadic preparation interact within the SC to influence saccadic reaction time. I concluded that saccade latency was strongly dependant on the spatial representation and interaction of visual and saccade related signals in the SC. Together, these findings provide novel insight into the neural m ...
... and saccadic preparation interact within the SC to influence saccadic reaction time. I concluded that saccade latency was strongly dependant on the spatial representation and interaction of visual and saccade related signals in the SC. Together, these findings provide novel insight into the neural m ...
Chlorhexidine: The Gold Standard Antiplaque Agent
... chlorhexidine must be understood in order to be put into maximum use. Chlorhexidine was used as a broad spectrum antiseptic since the 1950’s. Its antibacterial action is due to the disruption of the bacterial cell membrane by the chlorhexidine molecules, increasing the permeability and resulting in ...
... chlorhexidine must be understood in order to be put into maximum use. Chlorhexidine was used as a broad spectrum antiseptic since the 1950’s. Its antibacterial action is due to the disruption of the bacterial cell membrane by the chlorhexidine molecules, increasing the permeability and resulting in ...
what`s the
... subtle problems with memory, attention and the ability to handle complex information may be experienced. This can affect everyday life, particularly when learning something new or doing something difficult. ...
... subtle problems with memory, attention and the ability to handle complex information may be experienced. This can affect everyday life, particularly when learning something new or doing something difficult. ...
Madhuca Indica JF Gmel. (Sapotaceae): An Overview
... of orthodox medicine [1]. Medicinal plants have provided the modern medicine with numerous plant derived therapeutic agents [2]. Many plants contain a variety of phytopharmaceuticals, which have very important applications in the fields of agriculture, human and veterinary medicine. Natural products ...
... of orthodox medicine [1]. Medicinal plants have provided the modern medicine with numerous plant derived therapeutic agents [2]. Many plants contain a variety of phytopharmaceuticals, which have very important applications in the fields of agriculture, human and veterinary medicine. Natural products ...
Modafinil attenuates reinstatement of cocaine seeking: role for
... Modafinil may be useful for treating stimulant abuse, but the mechanisms by which it acts to do so are unknown. Indeed, a primary effect of modafinil is to inhibit dopamine transport, which typically promotes rather than inhibits motivated behavior. Therefore, we examined the role of nucleus accumbe ...
... Modafinil may be useful for treating stimulant abuse, but the mechanisms by which it acts to do so are unknown. Indeed, a primary effect of modafinil is to inhibit dopamine transport, which typically promotes rather than inhibits motivated behavior. Therefore, we examined the role of nucleus accumbe ...
Diabetes
... • Glucose entry into fat cells is insulin-dependent • The fat cell is the storage place for triglycerides • The pathway of taking triglycerides into the fat is promoted by insulin – In people with type 1 diabetes, insulin is not produced, so triglycerides are not taken into the fat cells • This expl ...
... • Glucose entry into fat cells is insulin-dependent • The fat cell is the storage place for triglycerides • The pathway of taking triglycerides into the fat is promoted by insulin – In people with type 1 diabetes, insulin is not produced, so triglycerides are not taken into the fat cells • This expl ...
Neuropharmacological Dissection of Placebo
... Drug administration. All drugs used in the present study were administered through an intravenous line. Before starting the experimental procedure, a needle was inserted into a vein of the dominant forearm. The needle was connected to a line, 1 m long, through which a slow inf usion of 5% glucose so ...
... Drug administration. All drugs used in the present study were administered through an intravenous line. Before starting the experimental procedure, a needle was inserted into a vein of the dominant forearm. The needle was connected to a line, 1 m long, through which a slow inf usion of 5% glucose so ...
Ministerstvo zdravotnictva SR k d. k. s04544-oKCLP-2012
... K intake, hypersensitivity to vitamin K, and rapid drug deactivation. Patient education is necessary to improve compliance and to mitigate adverse effects of warfarin therapy, regardless of the dose. In time, it may be possible to individualize anticoagulant dosing on the basis of genetic testing fo ...
... K intake, hypersensitivity to vitamin K, and rapid drug deactivation. Patient education is necessary to improve compliance and to mitigate adverse effects of warfarin therapy, regardless of the dose. In time, it may be possible to individualize anticoagulant dosing on the basis of genetic testing fo ...
Abstract - Earth Journals
... flavonoid content, chelating activity, reducing power and antioxidant/radical scavenging activity [1,1diphenyl-2-picryl-hydrazyl (DPPH°) free radical scavenging activity]. Results from different parameters were in agreement with each other. The results reveal that all extracts of the fenugreek exhib ...
... flavonoid content, chelating activity, reducing power and antioxidant/radical scavenging activity [1,1diphenyl-2-picryl-hydrazyl (DPPH°) free radical scavenging activity]. Results from different parameters were in agreement with each other. The results reveal that all extracts of the fenugreek exhib ...
Pharmaceutical Care in PET Imaging: Emphasis on [ F]FDG Imaging
... Of these agents, only three have been recognized by the FDA. Rubidium Rb82 is a commerciallyavailable, generator-produced PET radiopharmaceutical indicated for myocardial perfusion imaging (CardioGen-82®). Ammonia N13 and Fludeoxyglucose F18 have FDA- and CMS-approved indications, but only Fludeoxyg ...
... Of these agents, only three have been recognized by the FDA. Rubidium Rb82 is a commerciallyavailable, generator-produced PET radiopharmaceutical indicated for myocardial perfusion imaging (CardioGen-82®). Ammonia N13 and Fludeoxyglucose F18 have FDA- and CMS-approved indications, but only Fludeoxyg ...
Guidelines on Similar Biologic: Regulatory Requirements for
... Although the extent of testing of the Similar Biologic is likely to be less than that required for the Reference Biologic, it is essential that the testing of the Similar Biologic be sufficient to ensure that the product meets acceptable levels of safety, efficacy and quality to ensure public health ...
... Although the extent of testing of the Similar Biologic is likely to be less than that required for the Reference Biologic, it is essential that the testing of the Similar Biologic be sufficient to ensure that the product meets acceptable levels of safety, efficacy and quality to ensure public health ...
New Treatment Approaches in Tinnitus: The Place of Repetitive
... many parameters affecting the cortical activity and, in turn, the clinical outcome. These parameters also include the direction of the current in the coil, phases, and the major activity of the stimulated brain region (31, 32). Repetitive Transcranial Magnetic Stimulation, as a research method, has ...
... many parameters affecting the cortical activity and, in turn, the clinical outcome. These parameters also include the direction of the current in the coil, phases, and the major activity of the stimulated brain region (31, 32). Repetitive Transcranial Magnetic Stimulation, as a research method, has ...
Disassembling bacterial extracellular matrix with
... biodegradable nanoparticles (NPs) made up of the biocompatible poly(lactic-co-glycolic acid) (PLGA), have been investigated as drug delivery vehicles. A wide array of methods to fabricate such NPs is available, and most of them are easy to scale-up [10], and allow the encapsulation of several compou ...
... biodegradable nanoparticles (NPs) made up of the biocompatible poly(lactic-co-glycolic acid) (PLGA), have been investigated as drug delivery vehicles. A wide array of methods to fabricate such NPs is available, and most of them are easy to scale-up [10], and allow the encapsulation of several compou ...
Fourth_amended_complaint_restricted.pdf1165439753581
... Abbott’s AWP Manipulation Benefited Providers at the Expense of the Class .................................................................................................................64 ...
... Abbott’s AWP Manipulation Benefited Providers at the Expense of the Class .................................................................................................................64 ...
EFFECTS OF POMEGRANATE JUICE ON HUMAN CYTOCHROME
... pomegranate juice. Therefore, to confirm this hypothesis, the effects of pomegranate juice on the absorption of carbamazepine were tested. The absorption of carbamazepine from various parts of the rat intestine was examined in the presence or absence of pomegranate juice by the in situ closed loop t ...
... pomegranate juice. Therefore, to confirm this hypothesis, the effects of pomegranate juice on the absorption of carbamazepine were tested. The absorption of carbamazepine from various parts of the rat intestine was examined in the presence or absence of pomegranate juice by the in situ closed loop t ...
Evaluation of Pharmacokinetic Interaction between PA
... against M. tuberculosis isolates resistant to single or multiple antituberculous drugs and has proven effective in shortening treatment time of drug-sensitive M. tuberculosis in a murine model of tuberculosis (TB) as part of novel drug regimens (4). Moreover, PA-824 was highly active as monotherapy ...
... against M. tuberculosis isolates resistant to single or multiple antituberculous drugs and has proven effective in shortening treatment time of drug-sensitive M. tuberculosis in a murine model of tuberculosis (TB) as part of novel drug regimens (4). Moreover, PA-824 was highly active as monotherapy ...
Wild type human TDP-43 potentiates ALS-linked mutant TDP
... The identification of mutations in the glycine-rich C terminal region of TDP-43 that enhance protein cleavage, aggregation and neurotoxicity confirmed a pathologenic role for TDP-43 mis-accumulation in ALS and FTLD [6, 7, 8]. TDP-43 positive inclusions have also been identified in patients with path ...
... The identification of mutations in the glycine-rich C terminal region of TDP-43 that enhance protein cleavage, aggregation and neurotoxicity confirmed a pathologenic role for TDP-43 mis-accumulation in ALS and FTLD [6, 7, 8]. TDP-43 positive inclusions have also been identified in patients with path ...
CHAPTER 8 CEREBRAL CREATINE DEFICIENCY SYNDROMES
... with speech and language delay, expressive language disorder, epileptic seizures, behaviour disorders and gastrointestinal problems in adult patients (Kleefstra et al., 2005). A neuropsychological profile was obtained for four affected Dutch boys from two unrelated families and revealed hyperactive ...
... with speech and language delay, expressive language disorder, epileptic seizures, behaviour disorders and gastrointestinal problems in adult patients (Kleefstra et al., 2005). A neuropsychological profile was obtained for four affected Dutch boys from two unrelated families and revealed hyperactive ...
INHIBITION OF OAT3-MEDIATED RENAL UPTAKE AS A
... vector-HEK. The uptake of fexofenadine by hOAT3-HEK was significantly greater than that in vector-HEK at all time points, whereas the uptake by hOAT1-, hOAT2-, and hOCT2-HEK was very similar to that of vector-HEK (Fig. 1). Since the uptake of fexofenadine by hOAT3HEK increased linearly up to 5 min o ...
... vector-HEK. The uptake of fexofenadine by hOAT3-HEK was significantly greater than that in vector-HEK at all time points, whereas the uptake by hOAT1-, hOAT2-, and hOCT2-HEK was very similar to that of vector-HEK (Fig. 1). Since the uptake of fexofenadine by hOAT3HEK increased linearly up to 5 min o ...
Full-Text PDF
... exists on their diagnostic value in human idiosyncratic DILI [40]. Microarray RNAs circulating in the blood may be found with low levels in healthy individuals and with higher levels in patients with various diseases such as cancer, cell and organ transplantation, coronary heart disease, stroke, sep ...
... exists on their diagnostic value in human idiosyncratic DILI [40]. Microarray RNAs circulating in the blood may be found with low levels in healthy individuals and with higher levels in patients with various diseases such as cancer, cell and organ transplantation, coronary heart disease, stroke, sep ...
Aalborg Universitet Human Experimental Pain Models
... that life is more than achieving yet another goal in an academic career. I am lucky to have them in my life and I am them truly grateful. In particular, I would like to express my sincerest thanks and appreciation to my parents for their emotional support no matter what path I choose in life; this a ...
... that life is more than achieving yet another goal in an academic career. I am lucky to have them in my life and I am them truly grateful. In particular, I would like to express my sincerest thanks and appreciation to my parents for their emotional support no matter what path I choose in life; this a ...
Document
... Becomes continuous with central canal of the spinal cord Connects with third ventricle: – via narrow canal in mesencephalon – aqueduct of midbrain Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
... Becomes continuous with central canal of the spinal cord Connects with third ventricle: – via narrow canal in mesencephalon – aqueduct of midbrain Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
The Brain and Cranial Nerves
... Connects with third ventricle: – via narrow canal in mesencephalon – aqueduct of midbrain Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
... Connects with third ventricle: – via narrow canal in mesencephalon – aqueduct of midbrain Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
Cathinone derivatives: A review of their chemistry, pharmacology
... number of cathinone-related substances. However, by the middle of the next decade, matters began to change with a number of cathinone derivatives appearing as ‘legal highs’, initially only in certain countries. For example, methylone emerged for sale under the trade name ‘Explosion’ around 2004 in J ...
... number of cathinone-related substances. However, by the middle of the next decade, matters began to change with a number of cathinone derivatives appearing as ‘legal highs’, initially only in certain countries. For example, methylone emerged for sale under the trade name ‘Explosion’ around 2004 in J ...