Toward a general psychological model of tension and suspense
... contexts, experiences of tension are associated with negative emotions such as fear, concern, or distress, which are generally tried to be avoided; in other contexts, tension is experienced as positive, and can, in fact, be a major motivator to engage in certain activities. The appeal of many forms ...
... contexts, experiences of tension are associated with negative emotions such as fear, concern, or distress, which are generally tried to be avoided; in other contexts, tension is experienced as positive, and can, in fact, be a major motivator to engage in certain activities. The appeal of many forms ...
Potential applications of chitosan in veterinary medicine
... Chitosan is a partially deacetylated polymer obtained from the alkaline deacetylation of chitin which is a glucose-based unbranched polysaccharide widely distributed in nature as the principal component of exoskeletons of crustaceans and insects as well as of cell walls of some bacteria and fungi. C ...
... Chitosan is a partially deacetylated polymer obtained from the alkaline deacetylation of chitin which is a glucose-based unbranched polysaccharide widely distributed in nature as the principal component of exoskeletons of crustaceans and insects as well as of cell walls of some bacteria and fungi. C ...
Effects of grapefruit juice on the pharmacokinetics of selected
... protein, it participates in the biotransformation of a range of widely used drugs such as tricyclic antidepressants, neuroleptics, and β-blockers (Cholerton et al. 1992). CYP2D6 is not inducible, but can be inhibited by such drugs as quinidine, paroxetine and fluoxetine (Inaba et al. 1986; ...
... protein, it participates in the biotransformation of a range of widely used drugs such as tricyclic antidepressants, neuroleptics, and β-blockers (Cholerton et al. 1992). CYP2D6 is not inducible, but can be inhibited by such drugs as quinidine, paroxetine and fluoxetine (Inaba et al. 1986; ...
Acknowledgement - ResearchSpace@Auckland
... were selected and investigated for their ability to form niosomes and encapsulate NTX using different levels of cholesterol (a bilayer membrane stabiliser). Also, different membrane additives [dicetyl phosphate (DCP), Solulan C24 (C24) and sodium cholate (CH)] were studied to modify the physical pro ...
... were selected and investigated for their ability to form niosomes and encapsulate NTX using different levels of cholesterol (a bilayer membrane stabiliser). Also, different membrane additives [dicetyl phosphate (DCP), Solulan C24 (C24) and sodium cholate (CH)] were studied to modify the physical pro ...
An Updated Review of the Research on the Risks and Harms
... studies to build and improve upon the methodologies and results of past research, and therefore uncover things that were once unknown. ...
... studies to build and improve upon the methodologies and results of past research, and therefore uncover things that were once unknown. ...
battisti_nnconvulsions_en - ORBi
... Some also classify these as “hypomotor” seizures, which may present with activity arrest, apnea, or eye deviation. The art in diagnosing these as true seizures, and not just diagnosing every bowel movement as a seizure is in looking for any associated signs, such as autonomic changes like BP or HR i ...
... Some also classify these as “hypomotor” seizures, which may present with activity arrest, apnea, or eye deviation. The art in diagnosing these as true seizures, and not just diagnosing every bowel movement as a seizure is in looking for any associated signs, such as autonomic changes like BP or HR i ...
Poisoning and Drug Overdose
... Copyright © 2004 by The McGraw-Hill Companies, Inc. All rights reserved. Printed in the United States of America. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a data base or r ...
... Copyright © 2004 by The McGraw-Hill Companies, Inc. All rights reserved. Printed in the United States of America. Except as permitted under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a data base or r ...
An investigation of the sensory and motor innervation of extraocular
... immunolabelling. For the first time it was shown that both motoneurons types are present in rat as well. The MIF motoneurons lie mainly separated from the SIF motoneurons, and are different in size and histochemical properties. As in monkey, the smaller MIF motoneurons lack non-phosphorylated neurof ...
... immunolabelling. For the first time it was shown that both motoneurons types are present in rat as well. The MIF motoneurons lie mainly separated from the SIF motoneurons, and are different in size and histochemical properties. As in monkey, the smaller MIF motoneurons lack non-phosphorylated neurof ...
Pharmacological and Pharmaceutical Profile of Valsartan: A Review
... diseases like hypertension, heart failure, myocardial infarction and diabetic nephropathy. Their beneficial effects are related to inhibition of Angiotensin II by blockade of AT1 receptor. Valsartan is an orally active Angiotensin II receptor type 1 antagonist which causes reduction in blood pressur ...
... diseases like hypertension, heart failure, myocardial infarction and diabetic nephropathy. Their beneficial effects are related to inhibition of Angiotensin II by blockade of AT1 receptor. Valsartan is an orally active Angiotensin II receptor type 1 antagonist which causes reduction in blood pressur ...
Pharmacokinetic and pharmacodynamic drug interactions
... = 128.30 M), CYP2C19 (IC50 = 4.86 M) and CYP3A4 (IC50 = 34.48 M) and dihydrokavain inhibited CYP2C9 (IC50 = 130.95 M), CYP2C19 (IC50 = 10.05 M) and CYP3A4 (IC50 = 78.59 M). Yangonin could not be evaluated for its CYP inhibitory effect using the fluorimetric assay employed due to its high nativ ...
... = 128.30 M), CYP2C19 (IC50 = 4.86 M) and CYP3A4 (IC50 = 34.48 M) and dihydrokavain inhibited CYP2C9 (IC50 = 130.95 M), CYP2C19 (IC50 = 10.05 M) and CYP3A4 (IC50 = 78.59 M). Yangonin could not be evaluated for its CYP inhibitory effect using the fluorimetric assay employed due to its high nativ ...
The Role of Kv7 in Peripheral Neurons
... in the regulation of cellular excitability and axonal conduction. Previous studies have shown that peripheral sensory neurons express Kv7.2, Kv7.3, and Kv7.5 subunits, and that suppression of Kv7 activity with pharmacological blockers can lead to increased nociception. However, the specific localiza ...
... in the regulation of cellular excitability and axonal conduction. Previous studies have shown that peripheral sensory neurons express Kv7.2, Kv7.3, and Kv7.5 subunits, and that suppression of Kv7 activity with pharmacological blockers can lead to increased nociception. However, the specific localiza ...
Transungual Drug Delivery: An Overview
... Physical, chemical and mechanical methods have been used to decrease the nail barrier. Within each of these broad categories, many techniques exist to enhance penetration. Mechanical modes of penetration enhancement are typically straightforward, and have the most in vivo experience associated with ...
... Physical, chemical and mechanical methods have been used to decrease the nail barrier. Within each of these broad categories, many techniques exist to enhance penetration. Mechanical modes of penetration enhancement are typically straightforward, and have the most in vivo experience associated with ...
Sedation for diagnostic and therapeutic procedures in children and
... The aims of sedation during diagnostic or therapeutic procedures include reducing fear and anxiety, augmenting pain control and minimising movement. The importance of each of these aims will vary depending on the nature of the procedure and the characteristics of the patient. There are many sedation ...
... The aims of sedation during diagnostic or therapeutic procedures include reducing fear and anxiety, augmenting pain control and minimising movement. The importance of each of these aims will vary depending on the nature of the procedure and the characteristics of the patient. There are many sedation ...
MDMA in humans: factors which affect the neuropsychobiological
... employ objective and subjective measures in parallel. This would address the topic of their relative sensitivity/validity as measures. For instance, do users complain of memory/cognitive problems before they become apparent on objective tasks, or can the objective tasks reveal problems before they b ...
... employ objective and subjective measures in parallel. This would address the topic of their relative sensitivity/validity as measures. For instance, do users complain of memory/cognitive problems before they become apparent on objective tasks, or can the objective tasks reveal problems before they b ...
The ibogaine medical subculture
... enhances the regeneration of dopaminergic function (Ron and Janak, 2005) and is increased by antidepressant treatment (Hisaoka et al., 2007). The hypothesis that GDNF may mediate improvement in hedonic functioning and mood in chronic withdrawal from addictive substances is appealing, but does not ap ...
... enhances the regeneration of dopaminergic function (Ron and Janak, 2005) and is increased by antidepressant treatment (Hisaoka et al., 2007). The hypothesis that GDNF may mediate improvement in hedonic functioning and mood in chronic withdrawal from addictive substances is appealing, but does not ap ...
Review Biomedical applications of collagen
... long-term expression of human b-glucuronidase by retroviral-transduced murine or canine fibroblasts was achievable using a collagen-based matrix system. (Moullier et al., 1993a,b, 1995). Therefore, collagen-based film/disc systems seem to need to contain extra matrices that improve conditions for a ...
... long-term expression of human b-glucuronidase by retroviral-transduced murine or canine fibroblasts was achievable using a collagen-based matrix system. (Moullier et al., 1993a,b, 1995). Therefore, collagen-based film/disc systems seem to need to contain extra matrices that improve conditions for a ...
Esam Z. Dajani, Ph.D., FACG
... pharmaceutical patent litigations, Contract Research Organizations (CROs), drug injury causation, drug-related medical malpractice, medication errors, drug product liability, forensic aspects of alcohol intoxication and psychotropic drugs. He provides investigations, research, record analysis, consu ...
... pharmaceutical patent litigations, Contract Research Organizations (CROs), drug injury causation, drug-related medical malpractice, medication errors, drug product liability, forensic aspects of alcohol intoxication and psychotropic drugs. He provides investigations, research, record analysis, consu ...
Experimental extinction in Pavlovian conditioning
... paradigm for this purpose has been used recently by Blundell, Hall, and Killcross (2001). These investigators assessed the effects of basolateral amygdala lesions in rats on Pavlovianto-instrumental transfer. They observed that the normal tendency of CSs to exert selective control over instrumental ...
... paradigm for this purpose has been used recently by Blundell, Hall, and Killcross (2001). These investigators assessed the effects of basolateral amygdala lesions in rats on Pavlovianto-instrumental transfer. They observed that the normal tendency of CSs to exert selective control over instrumental ...
MICROMEDEX® Healthcare Series OXCARBAZEPINE
... compared to adults (Prod Info TRILEPTAL(R) oral tablets, oral suspension, 2005) a) Partial seizure, monotherapy 1) 4 to 16 year old, initiation of monotherapy, 8-10 mg/kg/day ORALLY divided doses; may increase dose by 5 mg/kg/day every 3 days to the recommended maintenance dose (Prod Info TRILEPTAL( ...
... compared to adults (Prod Info TRILEPTAL(R) oral tablets, oral suspension, 2005) a) Partial seizure, monotherapy 1) 4 to 16 year old, initiation of monotherapy, 8-10 mg/kg/day ORALLY divided doses; may increase dose by 5 mg/kg/day every 3 days to the recommended maintenance dose (Prod Info TRILEPTAL( ...
Cannabis Report of the Swiss Federal Commission For Drug Issues
... In the course of its initial meetings, the Federal Commission for Drug Issues (EKDF) mandated by the Swiss Federal Council in early 1997 drew up an assessment of the situation regarding drugs in Switzerland and of the current need for action. Its predecessor (the Subcommission for Drug Issues attach ...
... In the course of its initial meetings, the Federal Commission for Drug Issues (EKDF) mandated by the Swiss Federal Council in early 1997 drew up an assessment of the situation regarding drugs in Switzerland and of the current need for action. Its predecessor (the Subcommission for Drug Issues attach ...
R A EVIEW RTICLE
... The cardiovascular effects of nicotine in nonpregnant adults have been extensively studied.[3,5] Nicotine increases heart rate and myocardial contractility, constricts some blood vessels, and transiently increases blood pressure. For additional details and references, the reader is referred to anoth ...
... The cardiovascular effects of nicotine in nonpregnant adults have been extensively studied.[3,5] Nicotine increases heart rate and myocardial contractility, constricts some blood vessels, and transiently increases blood pressure. For additional details and references, the reader is referred to anoth ...
Medical Emergencies and Adverse Events in Ecstasy Users
... This estimate is limited by a number of factors. Most importantly, the number of ecstasyrelated ED visits reported by DAWN may be over or under-estimated. Toxicology screens vary in their ability to detect MDMA. In a recent survey, approximately 1/3 of 2734 laboratories failed to detect MDMA that wa ...
... This estimate is limited by a number of factors. Most importantly, the number of ecstasyrelated ED visits reported by DAWN may be over or under-estimated. Toxicology screens vary in their ability to detect MDMA. In a recent survey, approximately 1/3 of 2734 laboratories failed to detect MDMA that wa ...
more information
... found diabetic control induction and endocrine disorders of Hashimoto’s throiditis, cancer and neurological disorders such as transverse myelitis, ALS amyotrophic lateral sclerosis etc. Dr Blaylock has written extensively on the Glutamate toxicity of Aspartame and Hydroperoxyl Radical damage to glia ...
... found diabetic control induction and endocrine disorders of Hashimoto’s throiditis, cancer and neurological disorders such as transverse myelitis, ALS amyotrophic lateral sclerosis etc. Dr Blaylock has written extensively on the Glutamate toxicity of Aspartame and Hydroperoxyl Radical damage to glia ...
