Medical Applications and Toxicities of Gallium Compounds
... non-Hodgkin’s lymphoma and bladder cancer. At least 4 separate clinical trials have demonstrated the anti-lymphoma activity of gallium nitrate administered as a single agent [24-27], while 3 additional trials have used it in combination with other antineoplastic agents to improve treatment outcome [ ...
... non-Hodgkin’s lymphoma and bladder cancer. At least 4 separate clinical trials have demonstrated the anti-lymphoma activity of gallium nitrate administered as a single agent [24-27], while 3 additional trials have used it in combination with other antineoplastic agents to improve treatment outcome [ ...
michelia champaca alba
... Michelia champaca is given with honey in cases of colic. The flower oil is useful in cephalalgia, opthalmia and gout 5. The bark is used as a stimulant, expectorant, astringent and febrifugal properties6. The dried root and roots bark, mixed with curdled milk, is useful as an application to absecess ...
... Michelia champaca is given with honey in cases of colic. The flower oil is useful in cephalalgia, opthalmia and gout 5. The bark is used as a stimulant, expectorant, astringent and febrifugal properties6. The dried root and roots bark, mixed with curdled milk, is useful as an application to absecess ...
dystonia update
... mapped on chromosome 18p11 haplotype in all 13 affected members of a large Canadian family53 ...
... mapped on chromosome 18p11 haplotype in all 13 affected members of a large Canadian family53 ...
New Perspectives on Dystonia
... haplotype in all 13 affected members of a large Canadian family53 ...
... haplotype in all 13 affected members of a large Canadian family53 ...
Contributions of CYP3A4, P-glycoprotein, and Serum Protein
... the intestine (i.e., the contribution by the liver need not be considered). Besides undergoing extensive first-pass metabolism, saquinavir, like several other HIV protease inhibitors, is actively secreted by P-gp (Kim et al., 1998a,b), an ATP-dependent efflux pump located, among other cell types, in ...
... the intestine (i.e., the contribution by the liver need not be considered). Besides undergoing extensive first-pass metabolism, saquinavir, like several other HIV protease inhibitors, is actively secreted by P-gp (Kim et al., 1998a,b), an ATP-dependent efflux pump located, among other cell types, in ...
Low-Dose Methotrexate: A Mainstay in the Treatment of Rheumatoid
... doses to prevent proliferation of malignant cells and very low doses over prolonged periods to treat inflammatory diseases, the concentration of the drug used in a given in vitro experiment or the dose of the drug administered in vivo is critical. These considerations would suggest that many of the ...
... doses to prevent proliferation of malignant cells and very low doses over prolonged periods to treat inflammatory diseases, the concentration of the drug used in a given in vitro experiment or the dose of the drug administered in vivo is critical. These considerations would suggest that many of the ...
Clearing of Metabolic Waste via Enterohepatic Recirculation Table
... Thesis statement: The nature of bile lends itself to the recycling of metabolic waste, causing these waste products to reenter the blood stream through the process known as enterohepatic recirculation. This recycling could possibly become a concern as exposure to potentially harmful waste products i ...
... Thesis statement: The nature of bile lends itself to the recycling of metabolic waste, causing these waste products to reenter the blood stream through the process known as enterohepatic recirculation. This recycling could possibly become a concern as exposure to potentially harmful waste products i ...
Potential Novel Uses of Thalidomide
... thalidomide are complex and not all studies are consistent in their findings. Indeed, there are some studies that report contradictory observations. Overall, it does not seem possible to identify a single dominant mechanism of action for thalidomide. The multiplicity of actions may explain the large ...
... thalidomide are complex and not all studies are consistent in their findings. Indeed, there are some studies that report contradictory observations. Overall, it does not seem possible to identify a single dominant mechanism of action for thalidomide. The multiplicity of actions may explain the large ...
levocarb CR
... Isoniazid: Isoniazid may reduce the therapeutic effects of levodopa. Iron Salts: Iron salts may reduce the bioavailability of levodopa and carbidopa. The clinical relevance is unclear. Metoclopramide: Although metoclopramide may increase the bioavailability of levodopa by increasing gastric emptying ...
... Isoniazid: Isoniazid may reduce the therapeutic effects of levodopa. Iron Salts: Iron salts may reduce the bioavailability of levodopa and carbidopa. The clinical relevance is unclear. Metoclopramide: Although metoclopramide may increase the bioavailability of levodopa by increasing gastric emptying ...
Qualitative research of online drug misuse communities with
... 3. To understand the subjective experience, the reasons for use, preference, combinations, any new insights about the drug misuse communities, sale websites etc; 4. To explore a wide range of toxic effects experienced by the users, either short- or long-term and to identify any reports of deaths rel ...
... 3. To understand the subjective experience, the reasons for use, preference, combinations, any new insights about the drug misuse communities, sale websites etc; 4. To explore a wide range of toxic effects experienced by the users, either short- or long-term and to identify any reports of deaths rel ...
- University of Glasgow
... (µ) opioid receptor agonists are known respiratory depressants. The activity of the preBötC is depressed by µ opioids in vitro. Furthermore, fentanyl, a potent µ opioid receptor agonist, evokes respiratory frequency depression in vivo by exclusively targeting and depressing preBötC neurons. Converse ...
... (µ) opioid receptor agonists are known respiratory depressants. The activity of the preBötC is depressed by µ opioids in vitro. Furthermore, fentanyl, a potent µ opioid receptor agonist, evokes respiratory frequency depression in vivo by exclusively targeting and depressing preBötC neurons. Converse ...
Kratom - NeuroSoup
... this alkaloid. Given that nearly all the chemical studies of kratom have been done on the assumption that mitragynine was the most important alkaloid, and that nearly all pharmacological ...
... this alkaloid. Given that nearly all the chemical studies of kratom have been done on the assumption that mitragynine was the most important alkaloid, and that nearly all pharmacological ...
Cumming BG, Parker AJ.
... It would have been possible to manipulate the relative disparity between the foreground and background of the RDS simply by changing the disparity of the background region. However, in such an experiment, the absence of an effect of relative disparity would be hard to interpret. It is always possibl ...
... It would have been possible to manipulate the relative disparity between the foreground and background of the RDS simply by changing the disparity of the background region. However, in such an experiment, the absence of an effect of relative disparity would be hard to interpret. It is always possibl ...
Buprenorphine (with or without naloxone)
... Tablets can also be more easily diverted than liquids, because of their longer absorption time. Buprenorphine is safer in overdose Buprenorphine has a better safety profile in overdose when not used in combination with other drugs than does methadone. This is due to the partial agonist effect that c ...
... Tablets can also be more easily diverted than liquids, because of their longer absorption time. Buprenorphine is safer in overdose Buprenorphine has a better safety profile in overdose when not used in combination with other drugs than does methadone. This is due to the partial agonist effect that c ...
the Report - The Lasker Foundation
... amblyopia, if refractive error is a contributing factor, the first step in treatment is appropriate refractive correction. (There is some debate as to whether correction of strabismus alone can have a positive impact on strabismic amblyopia.) Once the underlying anomaly is corrected, the current sta ...
... amblyopia, if refractive error is a contributing factor, the first step in treatment is appropriate refractive correction. (There is some debate as to whether correction of strabismus alone can have a positive impact on strabismic amblyopia.) Once the underlying anomaly is corrected, the current sta ...
PREZISTA® (darunavir) oral suspension PREZISTA® (darunavir
... symptoms and acute generalized exanthematous pustulosis, have been reported. Discontinue treatment if severe reaction develops. (5.3, 6) • Use with caution in patients with a known sulfonamide allergy. (5.4) • The concomitant use of PREZISTA/ritonavir and certain other drugs may result in known or ...
... symptoms and acute generalized exanthematous pustulosis, have been reported. Discontinue treatment if severe reaction develops. (5.3, 6) • Use with caution in patients with a known sulfonamide allergy. (5.4) • The concomitant use of PREZISTA/ritonavir and certain other drugs may result in known or ...
Previous results from our laboratory have shown that administration
... beginning as early as 11 years old. Early initiation of drinking behavior is indicative of an increased risk for future substance abuse problems. This may stem from ethanol-induced changes in the brain that could potentially increase the rewarding properties of ethanol, making a person more likely t ...
... beginning as early as 11 years old. Early initiation of drinking behavior is indicative of an increased risk for future substance abuse problems. This may stem from ethanol-induced changes in the brain that could potentially increase the rewarding properties of ethanol, making a person more likely t ...
NEURAL MECHANISMS SUPPORTING THE LEARNING
... several brain regions that showed learning-related changes (Dunsmoor et al., 2008; Wood et al., 2012). For example, UCS expectancy increased during the CS and the amplitude of the fMRI signal response to the UCS within these brain regions decreased (Dunsmoor et al., 2008). Similar findings have been ...
... several brain regions that showed learning-related changes (Dunsmoor et al., 2008; Wood et al., 2012). For example, UCS expectancy increased during the CS and the amplitude of the fMRI signal response to the UCS within these brain regions decreased (Dunsmoor et al., 2008). Similar findings have been ...
RTF format
... injury, that would fall into the category of severe brain injuries by the criteria we use for defining mild, moderate and severe brain injuries. We knew he has a severe primary diffuse brain injury which is complicated by cerebral laceration and by cerebral swelling it is just that much more severe. ...
... injury, that would fall into the category of severe brain injuries by the criteria we use for defining mild, moderate and severe brain injuries. We knew he has a severe primary diffuse brain injury which is complicated by cerebral laceration and by cerebral swelling it is just that much more severe. ...
Emotional experiences of tension and suspense: psychological
... Tension and suspense are ubiquitous emotional phenomena that are experienced in a multitude of contexts (e.g., in music, literature, film, sports, or everyday life). However, the psychological and neuronal mechanisms underlying tension experiences remain largely unclear. This dissertation aims to ad ...
... Tension and suspense are ubiquitous emotional phenomena that are experienced in a multitude of contexts (e.g., in music, literature, film, sports, or everyday life). However, the psychological and neuronal mechanisms underlying tension experiences remain largely unclear. This dissertation aims to ad ...
Investigator`s Brochure - Multidisciplinary Association for
... to others, wellbeing, and insightfulness [29-31]. Prior to scheduling in 1985, MDMA was used in individual, couple, and group therapy to treat diverse psychological disorders, including moderate depression and anxiety [30, 32] [33, 34]. It was also found to be useful in reducing physical pain second ...
... to others, wellbeing, and insightfulness [29-31]. Prior to scheduling in 1985, MDMA was used in individual, couple, and group therapy to treat diverse psychological disorders, including moderate depression and anxiety [30, 32] [33, 34]. It was also found to be useful in reducing physical pain second ...
idarubicin
... idarubicin total cumulative doses up to 400 mg/m2 suggest a low probability of cardiotoxicity. Cardiac function should be assessed before patients undergo treatment with idarubicin and must be monitored throughout therapy to minimize the risk of incurring severe cardiac impairment. The risk may be d ...
... idarubicin total cumulative doses up to 400 mg/m2 suggest a low probability of cardiotoxicity. Cardiac function should be assessed before patients undergo treatment with idarubicin and must be monitored throughout therapy to minimize the risk of incurring severe cardiac impairment. The risk may be d ...
Pharmacology of platelet inhibition in humans: implications of the
... ABSTRACT The current dispute over the effects of "low" vs "high"doses of aspirin should take into consideration the pharmacokinetics of this drug. In fact, different pharmaceutical formulations of aspirin may deliver little or no aspirin to the systemic blood. This was the case, for instance, in hea ...
... ABSTRACT The current dispute over the effects of "low" vs "high"doses of aspirin should take into consideration the pharmacokinetics of this drug. In fact, different pharmaceutical formulations of aspirin may deliver little or no aspirin to the systemic blood. This was the case, for instance, in hea ...
Corticotropin-releasing Factor: Long
... However, the magnitude and time course differed considerably from that previously reported. The facilitatory effect did not appear until approximately 20-30 min after icv infusion, was very large, and persisted for many hours. The present series of experiments sought to characterize this finding mor ...
... However, the magnitude and time course differed considerably from that previously reported. The facilitatory effect did not appear until approximately 20-30 min after icv infusion, was very large, and persisted for many hours. The present series of experiments sought to characterize this finding mor ...
5-country RAR report
... What is the extent and nature of NPS use among PUDH in the selected countries? a. What are the recent trends and developments in NPS use among PUDH? b. What patterns of use can be distinguished? ...
... What is the extent and nature of NPS use among PUDH in the selected countries? a. What are the recent trends and developments in NPS use among PUDH? b. What patterns of use can be distinguished? ...