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2.3.3 Protein and amino acid metabolism
2.3.3 Protein and amino acid metabolism

... disposal of amino acids involves the conversion of their carbon skeletons to glucose and to ketone bodies, which are released, as universal fuels, for other tissues. This enables the liver to accommodate dietary amino acid disposal within the bounds of its oxygen consumption. In an adult in nitrogen ...
Genome-Based Metabolic Mapping and C Flux
Genome-Based Metabolic Mapping and C Flux

... G6P, glucose-6-phosphate; Glx, glyoxylate; Go3P, glycerol-3-phosphate; Gr, glycerate; Hpyr, hydroxypyruvate; Isocit, isocitrate; Lac, lactate; Mal, malate; OAA, oxaloacetate; 3PG, 3-phosphoglycerate; P5P, pentose-5-phosphate; PEP, phosphoenolpyruvate; PGI, phosphoglycolate; PGluc, 6-phosphogluconate ...
heartsprotein.adv.pdf
heartsprotein.adv.pdf

... acids appear will determine the 3 dimensional shape of the protein. Interactions between the different R groups will cause the protein to assume and maintain a specific structure. When proteins fold, different amino acids that are distant from each other in the long chain of amino acids, may be near ...
Organotins-promoted peroxidation of unsaturated fatty acids: A new
Organotins-promoted peroxidation of unsaturated fatty acids: A new

... (CH3 )2 SnCl2 , (C2 H5 )2 SnCl2 , and SnCl2 upon the radical chain oxidation of oleic acid as model substrate R H for lipid peroxidation in the simultaneous presence of porphyrins (free bases of meso-tetrakis(3,5-ditert-butyl-4-hydroxyphenyl)porphyrin (R4 PH2 ) and of meso-tetraphenylporphyrin (T ...
CELLULAR RESPIRATION
CELLULAR RESPIRATION

... Carried out by certain bacteria Electron transport system is in bacterial plasma membrane ...
Studies on the Physiological Significance of the Lack
Studies on the Physiological Significance of the Lack

... reached 0.48 mg dry wt/ml (about 16 h). The cells were harvested by centrifugation (10000 g; 20 min, 4 "C) and washed twice in 10 ml of a 60 mM solution of the homologous non-radioactive compound and once in distilled water. The pellet was resuspended in distilled water (I ml) and transferred to gla ...
BioCore II lecture20-S2015
BioCore II lecture20-S2015

... Describe how pyruvate, the product of glycolysis, is prepared for entry into the citric acid cycle ...
Respiration - Fort Thomas Independent Schools
Respiration - Fort Thomas Independent Schools

... • Uses only Glycolysis. • An incomplete oxidation - energy is still left in the products (lactic acid). • Does NOT require O2 • Produces ATP when O2 is not available. ...
METABOLISM CATABOLISM
METABOLISM CATABOLISM

... and low on other side) – e.g. water and small lipids go across this way -facilitated - move with concentration gradienthigh in small intestine and low on other side-presence of carrier (regulation -amount and activity of carrier)- e.g. fructose and water soluble vitamins go across this way. ...
PowerPoint プレゼンテーション
PowerPoint プレゼンテーション

... produces dextrins and maltose. Maltase is also present in pancreatic juice and it hydrolyses maltose to glucose. ...
an introduction to alpha-fetoprotein and the growth inhibitory peptide
an introduction to alpha-fetoprotein and the growth inhibitory peptide

... transreticular portion of the golgi apparatus. Fatty acids bound to AFP are transferred into cells within 5 minutes at 37°C, and, following fatty acid release, AFP can be recycled back across the cell surface. In short it followed receptor mediated endocytosis. Data revealed that the fatty acids bou ...
Table of Contents
Table of Contents

... Figure 7.9 The Citric Acid Cycle Releases Much More Free Energy Than Glycolysis Does ...
Ch18.doc
Ch18.doc

... It is obvious that the patient’s urine is abnormally high in phenylalanine, and products typical of phenylketonuria: phenylpyruvate and phenyllactate. So: a. Deficient or missing enzyme: phenylalanie hydroxylase. Treatment: life long diet low in ...
Chemistry of Natural Compounds
Chemistry of Natural Compounds

... form of a methyl group, derived from L-methionine (Figure 1.A). A two carbon atom unit is frequently supplied by acetyl coenzyme A (acetyl-CoA, Figure 1.B). The acetyl group is the building block of choice for the construction of a long alkyl chain (as in fatty acids) or may be part of aromatic syst ...
The Outer Membrane of Gram-negative Bacteria and - Beck-Shop
The Outer Membrane of Gram-negative Bacteria and - Beck-Shop

... lipid-soluble molecules simply diffuse across the phospholipid bilayer, diffusion being powered by the potential energy of a concentration gradient and does not require the expenditure of metabolic energy. All other molecules require carrier molecules to transport them through the membrane. Mechanis ...
Membrane Lipid Integrity Relies on a Threshold of ATP Production
Membrane Lipid Integrity Relies on a Threshold of ATP Production

... instance, changes in membrane lipids have mostly been studied during aging, and have been related to overall lipid unsaturation, lipid degradation, and peroxidation processes (Knowles and Knowles, 1989; Spychalla and Desborough, 1990a, 1990b; Kumar and Knowles, 1993; Dipierro and De Leonardis, 1997) ...
Lecture 7 Animal Energy Acquisition II: Food acquisition and
Lecture 7 Animal Energy Acquisition II: Food acquisition and

... Gallbladder: stores bile. Pancreas: Important roles as both an endocrine and exocrine organ - provides a potent mixture of digestive enzymes to the small intestine which are critical for digestion of fats, carbohydrates and protein. Small Intestine: The most exciting place to be in the entire digest ...
Statistical Selection of Amino Acids Fortifying a Minimal Defined
Statistical Selection of Amino Acids Fortifying a Minimal Defined

... In addition, the use of minimal defined media might be more cost-effective than using complex rich media due to the lower medium costs with no requirement for the removal of unknown complex compounds during downstream processes [16]. However, complex media based on yeast extract and peptone have bee ...
The Cardiovascular System and Exercise
The Cardiovascular System and Exercise

... The other substrates that can the body can use to produce ATP include fat, carbohydrate and protein. Fat is stored predominantly as adipose tissue throughout the body and is a substantial energy reservoir. Fat is less accessible for cellular metabolism as it must first be reduced from its complex fo ...
Amino Acids Metabolism: Disposal of Nitrogen.
Amino Acids Metabolism: Disposal of Nitrogen.

... -Low level of energy (decrease ATP)  increase catabolism of a.a α-ketoglutarate as substrate for TCA cycle. - The enzyme glutamate dehydrogenase presents in mitochondrial matrix and can use either NAD+ or NADP+ as oxidants. *The oxidative deamination results in: - Liberation of the amino group as ...
supporting information
supporting information

... Correspondence concerning this article should be addressed to Raymond Zeng at ...
sheet#30
sheet#30

... citrulline which leaves the mitochondria. Now citrulline carries two out of the three groups that are present in urea. The third group which is the second amino group is taken from aspartate. 6|Page ...
red blood cell (rbc) membrane and enzyme disorders
red blood cell (rbc) membrane and enzyme disorders

... Fully compensated hemolysis (without anemia) to severe hemolytic anemia requiring regular transfusions Presentation at later age vs neonatal death (hydrops fetalis) No correlation between residual enzyme activity and clinical severity Exacerbation of hemolysis during infection In some cases also non ...
Problem-Set Solutions
Problem-Set Solutions

... glycolytic pathway. Glycogenolysis in muscle and brain cells produces glucose 6-phosphate, which can enter the glycolytic pathway as the first intermediate in that pathway. Since brain and muscle cells do not produce glucose, these cells can use glycogen for energy production only. 24.64 It enters a ...
Pyruvate dehydrogenase complex
Pyruvate dehydrogenase complex

... Hans Krebs showed that the oxidation of acetate is accomplished by a cycle TCA cycle, Citric Acid Cycle or Krebs Cycle • Pyruvate from glycolysis is oxidatively decarboxylated to acetate and then degraded to CO2 in TCA cycle • Some ATP is produced • More NADH and FADH2 are made • NADH goes on to ma ...
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Fatty acid metabolism

Fatty acids are a family of molecules classified within the lipid macronutrient class. One role of fatty acids within animal metabolism is energy production in the form of adenosine triphosphate (ATP) synthesis. When compared to other macronutrient classes (carbohydrates and protein), fatty acids yield the most ATP on an energy per gram basis by a pathway called β-oxidation. In addition, fatty acids are important for energy storage, phospholipid membrane formation, and signaling pathways. Fatty acid metabolism consists of catabolic processes that generate energy and primary metabolites from fatty acids, and anabolic processes that create biologically important molecules from fatty acids and other dietary sources.
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