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AntihistaminesJC
AntihistaminesJC

... Common Structures of Antihistamines Treatments Future Ideas for Dealing with Allergies ...
Great events in history of transplantation
Great events in history of transplantation

... treatment of human disease – In 1954, the first successful human kidney transplant was performed between twins in Boston. – Transplants were possible in unrelated people if drugs were taken to suppress the body's immune reaction Great events in history of transplantation Immunology ...
7HealthandImmuneSystem11
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bacteriophages
bacteriophages

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Common Concepts of Immune Defense
Common Concepts of Immune Defense

... the adaptive immune mechanisms were urgently required and initiated then, some 500 million years ago (Kaufman 2010). This was not only confined to jawed vertebrates, but also invertebrates developed specific adaptive immune mechanisms (Adema et al. 1997; Zhang et al. 2004) (Fig. 13.1). Thus from the ...
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... • The first exposure to a specific antigen represents the primary immune response • During this time, effector B cells called plasma cells are generated, and T cells are activated to their effector forms • In the secondary immune response, memory cells facilitate a faster, more efficient response ...
The Cellular Biology of the Reed-Sternberg Cell
The Cellular Biology of the Reed-Sternberg Cell

... lymphomas (NHLs)~than of HD itself. In fact, historically long-standing enigmas regarding the nature of HD continue to defy understanding. The most prominent of these enigmas concerns the origin of the Reed-Sternberg (RS) cell itself. It has been variously identified as a cell deriving from lineages ...
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Understanding Immunity by Tracing Thymocyte Development

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United States v. Moore: AIDS and the Criminal Law

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... Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555-0609, USA ...
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Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry

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General Summary - edoc

... accumulated recently suggesting that ectosomes act as vesicular mediators that adopt cellspecific functions, most of which being of pro-coagulant or pro–inflammatory nature. Described functions range from inter-cellular transfer of CCR5 and tissue factor from mononuclear cells and platelets, respect ...
IDF Care Guidelines - University Hospitals
IDF Care Guidelines - University Hospitals

... body weight. Trough (pre-dose) blood levels of IgG can be evaluated more frequently initially and at least once a year after that to determine if there has been a change in the pharmacokinetics and resultant blood levels of IgG in a specific individual. Dose adjustments are obviously necessary durin ...
A Newly Isolated Bacteriophage, PBES 02, Infecting Cronobacter
A Newly Isolated Bacteriophage, PBES 02, Infecting Cronobacter

... Myoviridae as observed under a transmission electron microscope. The major virion protein appears to be 38 kilodaltons (kDa) in size. The latent period of PBES 02 is 30 min and the burst size is 250. Infectivity of the phage remained intact after exposure to temperatures ranging from 4oC to 55oC for ...
The pathogenic role of rheumatoid factor in rheumatoid arthritis
The pathogenic role of rheumatoid factor in rheumatoid arthritis

... sets capable of secreting RFs are likely to include both B1 and B2 cells, but the culprit subset may be variable depending on the biological condi­ tion that induces RF production. B1 cells have been shown to compose a major fraction that secretes large amounts of IgM RFs against the stimulation wit ...
Amino Acids : beyond the building blocks
Amino Acids : beyond the building blocks

... only crucial for growing poultry and swine with the rapid evolution of genotypes but also for reproducing animals (male pigs, layers, breeders, sows) with their increased productivity. However, it will not be the aim of the present review. The objective of the nutritionists has long been to optimize ...
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Monoclonal antibody



Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.
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