Duration of post-vaccination immunity against yellow - Arca
... municipality of Alfenas is located in Minas Gerais, which is a large state in southeast Brazil where vaccination against yellow fever is recommended at the age of 9 months. In the Alfenas region, there are no recorded cases of yellow fever. In Brazil, infections by flaviviruses other than dengue and ...
... municipality of Alfenas is located in Minas Gerais, which is a large state in southeast Brazil where vaccination against yellow fever is recommended at the age of 9 months. In the Alfenas region, there are no recorded cases of yellow fever. In Brazil, infections by flaviviruses other than dengue and ...
Detecting Cytokine Release from Single T-cells
... and protection against infections and is also monitored to determine vaccine efficacy.4,5 The functional heterogeneity of T-cells necessitates development of tools that help determine cytokine production of individual cells. In immunology, single cell level cytokine detection is traditionally perfor ...
... and protection against infections and is also monitored to determine vaccine efficacy.4,5 The functional heterogeneity of T-cells necessitates development of tools that help determine cytokine production of individual cells. In immunology, single cell level cytokine detection is traditionally perfor ...
Meningococcal C Conjugate Vaccines
... • Plans for Cameroon, Chad and Nigeria, then other countries • Given to 1-29 year olds • Cost less than 50 cents per dose • Estimated to prevent 1 million cases and save $300 million over the next decade http://www.meningvax.org/ ...
... • Plans for Cameroon, Chad and Nigeria, then other countries • Given to 1-29 year olds • Cost less than 50 cents per dose • Estimated to prevent 1 million cases and save $300 million over the next decade http://www.meningvax.org/ ...
Conjugate Vaccines - Immunize Canada
... • Plans for Cameroon, Chad and Nigeria, then other countries • Given to 1-29 year olds • Cost less than 50 cents per dose • Estimated to prevent 1 million cases and save $300 million over the next decade http://www.meningvax.org/ ...
... • Plans for Cameroon, Chad and Nigeria, then other countries • Given to 1-29 year olds • Cost less than 50 cents per dose • Estimated to prevent 1 million cases and save $300 million over the next decade http://www.meningvax.org/ ...
Analysis of Time to FDA Medwatch Safety Alert for Therapeutic Monoclonal Antibodies
... The analysis demonstrated a trend towards earlier reporting of predictable alerts, but without clear statistical significance. However, this finding should be interpreted taking into account the type of data analysed. Our study provides an innovative option for analysis of safety concerns. Such a ty ...
... The analysis demonstrated a trend towards earlier reporting of predictable alerts, but without clear statistical significance. However, this finding should be interpreted taking into account the type of data analysed. Our study provides an innovative option for analysis of safety concerns. Such a ty ...
Differential expression of surface membrane Trypanosoma congolense
... receptor, major histocompartibility (MHC) II complex (Ia antigen) and two monocyte/macrophage (M<\>) differentiation antigens. The study revealed that both cytokines caused the enhancement of the expression of all the PBM surface antigens studied . rBoiFN-y at low concentrations was more efficient i ...
... receptor, major histocompartibility (MHC) II complex (Ia antigen) and two monocyte/macrophage (M<\>) differentiation antigens. The study revealed that both cytokines caused the enhancement of the expression of all the PBM surface antigens studied . rBoiFN-y at low concentrations was more efficient i ...
Slide 1
... Coating or entrapment of many types of drugs, Cell and tissue targeting antigens, or sensors Sterile filtered and pyrogen free; lyophilized Hemocompatible to neutrophils, platelets, and RBCs Lack of toxicity ...
... Coating or entrapment of many types of drugs, Cell and tissue targeting antigens, or sensors Sterile filtered and pyrogen free; lyophilized Hemocompatible to neutrophils, platelets, and RBCs Lack of toxicity ...
The Body`s Defenses
... interact specifically with it. • In fact, B and T cells can distinguish among antigens with molecular shapes that are only slightly different, leading the immune system to target specific invaders. ...
... interact specifically with it. • In fact, B and T cells can distinguish among antigens with molecular shapes that are only slightly different, leading the immune system to target specific invaders. ...
Infectious bovine rhinotracheitis/infectious pustular vulvovaginitis
... Madin–Darby bovine kidney cell line, are all suitable. Cell cultures can be grown in glass or plastic tubes, plates or dishes. When 24-well plastic plates are used, a 100–200 µl volume of the supernatants described above is inoculated into these cell cultures. After a 1-hour adsorption period, the c ...
... Madin–Darby bovine kidney cell line, are all suitable. Cell cultures can be grown in glass or plastic tubes, plates or dishes. When 24-well plastic plates are used, a 100–200 µl volume of the supernatants described above is inoculated into these cell cultures. After a 1-hour adsorption period, the c ...
estrogen receptors in human thyroid gland
... fmol/mg, which is very low. It has been found in the breast that a level of 20 or more fmol/mg ...
... fmol/mg, which is very low. It has been found in the breast that a level of 20 or more fmol/mg ...
The effectiveness of a human tyrosinase DNA vaccine in dogs with
... catalyses the first reaction. Without tyrosinase, this reaction cannot occur and no melanin can be produced.16 Several studies using mice showed that no immune response occurred after administration of syngeneic tyrosinase. However, the immune system seemed to be triggered in C57BL/6 mice when using ...
... catalyses the first reaction. Without tyrosinase, this reaction cannot occur and no melanin can be produced.16 Several studies using mice showed that no immune response occurred after administration of syngeneic tyrosinase. However, the immune system seemed to be triggered in C57BL/6 mice when using ...
Peptide trafficking and translocation across membranes in
... blocks peptide binding to TAP [39,40]. For high-affinity inhibition, ICP47 is enriched at the ER membrane, thereby inducing a helix-loop-helix conformation [41]. The early gene product US6 of human cytomegalovirus represents an ER-resident type 1 membrane glycoprotein, which inhibits ATP binding to ...
... blocks peptide binding to TAP [39,40]. For high-affinity inhibition, ICP47 is enriched at the ER membrane, thereby inducing a helix-loop-helix conformation [41]. The early gene product US6 of human cytomegalovirus represents an ER-resident type 1 membrane glycoprotein, which inhibits ATP binding to ...
Antiviral Immunity in Amphibians
... defense. It includes the production of type I interferon (IFN) by infected cells, which inhibits virus replication by blocking protein synthesis in virus-infected cells and by enhancing natural killer (NK) cell-mediated cytotoxicity [21]. Activation of innate immune responses in vertebrates occurs t ...
... defense. It includes the production of type I interferon (IFN) by infected cells, which inhibits virus replication by blocking protein synthesis in virus-infected cells and by enhancing natural killer (NK) cell-mediated cytotoxicity [21]. Activation of innate immune responses in vertebrates occurs t ...
Granzyme A activates another way to die
... studied than GzmA, largely because it activates the caspase pathway, which is so important in developmental cell death. However, new evidence (73) (see below) suggests that the cell death pathway initiated by GzmA may also be activated in non-immune neuronal cell death, especially during ischemia an ...
... studied than GzmA, largely because it activates the caspase pathway, which is so important in developmental cell death. However, new evidence (73) (see below) suggests that the cell death pathway initiated by GzmA may also be activated in non-immune neuronal cell death, especially during ischemia an ...
Immunisation with proteins expressed during chronic
... has shown that a vaccine would be a cost-effective intervention in Thailand if used in high-risk populations such as diabetics [10]. However, at present there is no available human vaccine, though a wide range of candidates including live attenuated mutants, killed cells, protein or polysaccharide s ...
... has shown that a vaccine would be a cost-effective intervention in Thailand if used in high-risk populations such as diabetics [10]. However, at present there is no available human vaccine, though a wide range of candidates including live attenuated mutants, killed cells, protein or polysaccharide s ...
Mouse and human FcR effector functions
... disease but also of the pharmaceutical community, through the identification of FcRs as targets for therapy or engineering of Fc domains for the generation of enhanced therapeutic antibodies. The availability of knockout mouse lines for every single mouse FcR, of multiple or cell-specific—‘a la car ...
... disease but also of the pharmaceutical community, through the identification of FcRs as targets for therapy or engineering of Fc domains for the generation of enhanced therapeutic antibodies. The availability of knockout mouse lines for every single mouse FcR, of multiple or cell-specific—‘a la car ...
The Complement system
... • Eventially enough C3b is cleaved that the surface of the bacteria begins to become saturated with it. • C2b and C4b which make up the C3 activation complex has a slight affinity for C3b and C3b binds to them • When C3b binds to C2b and C4b it forms a new complex referred to as the C5 activation ...
... • Eventially enough C3b is cleaved that the surface of the bacteria begins to become saturated with it. • C2b and C4b which make up the C3 activation complex has a slight affinity for C3b and C3b binds to them • When C3b binds to C2b and C4b it forms a new complex referred to as the C5 activation ...
Methods. Anti-LFA-1 mAb was used in a multiple minor
... LFA-1 blockade induces long-term donor-specific regulation Less CAV with T cell graft infiltration represents either lack of anti-donor response or on-going donorspecific regulation. To further examine the existence of regulation or hyporesponsiveness in cardiac recipients, DTH responses in recipien ...
... LFA-1 blockade induces long-term donor-specific regulation Less CAV with T cell graft infiltration represents either lack of anti-donor response or on-going donorspecific regulation. To further examine the existence of regulation or hyporesponsiveness in cardiac recipients, DTH responses in recipien ...
The immune system
... We detect antibodies against etiological agent of the disease in a patients serum, i.e. non pathogenic P. vulgaris and not R. prowasekii, is used as antigen in this serological in vitro reaction A laboratory worker is protected from being infected ...
... We detect antibodies against etiological agent of the disease in a patients serum, i.e. non pathogenic P. vulgaris and not R. prowasekii, is used as antigen in this serological in vitro reaction A laboratory worker is protected from being infected ...
Exploring the reciprocal relationship between
... in a disease-susceptible host might occur through failure to down-regulate the inflammatory process. One prediction from this model is that effective mechanisms of immunoregulation might be most easily investigated in non-susceptible individuals. However, this has been difficult to study in man. Bas ...
... in a disease-susceptible host might occur through failure to down-regulate the inflammatory process. One prediction from this model is that effective mechanisms of immunoregulation might be most easily investigated in non-susceptible individuals. However, this has been difficult to study in man. Bas ...
The Role of a Cytophilic Factor from Challenged
... apparently lost cytotoxicity after incubation with trypsin. These macrophages could, however, be rearmed by incubation with the factor for 1 hr at 37 (Table 6). Complement. To test whether the factor was a complement dependent antibody, complement was added to SL2 cells suspended in the factor conta ...
... apparently lost cytotoxicity after incubation with trypsin. These macrophages could, however, be rearmed by incubation with the factor for 1 hr at 37 (Table 6). Complement. To test whether the factor was a complement dependent antibody, complement was added to SL2 cells suspended in the factor conta ...
FC Chimeric Fusion Protein Purified Human
... (FasL). Fas belongs to the TNF (tumor necrosis factor)/NGF (nerve growth factor) receptor family, and is expressed in various tissues and cells including the thymus, liver, ovary and lung. FasL is a member of the TNF cytokine family that induces apoptosis by binding to Fas, its cell-surface receptor ...
... (FasL). Fas belongs to the TNF (tumor necrosis factor)/NGF (nerve growth factor) receptor family, and is expressed in various tissues and cells including the thymus, liver, ovary and lung. FasL is a member of the TNF cytokine family that induces apoptosis by binding to Fas, its cell-surface receptor ...
Listeria Monocytogenes Protein Fraction Induces Dendritic Cells
... In the present study, we fractionated Listeria Monocytogenes-derived proteins by adding of ammonium sulfate in a stepwise manner. DCs were also generated from C57BL/6 mice bone marrow precursor cells. Then, the effects of protein fractions on bone marrow derived DC (BMDC) maturation were evaluated. ...
... In the present study, we fractionated Listeria Monocytogenes-derived proteins by adding of ammonium sulfate in a stepwise manner. DCs were also generated from C57BL/6 mice bone marrow precursor cells. Then, the effects of protein fractions on bone marrow derived DC (BMDC) maturation were evaluated. ...
Correlations among measles virus
... correlates of protection against measles. Vaccine failure has been defined in terms of antibody response alone, and the markers of measles virus-specific cellular immunity after vaccination have been poorly characterized. Although the role and relative contribution of cellular immunity in imparting ...
... correlates of protection against measles. Vaccine failure has been defined in terms of antibody response alone, and the markers of measles virus-specific cellular immunity after vaccination have been poorly characterized. Although the role and relative contribution of cellular immunity in imparting ...
Monoclonal antibody
Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.