Andrea Kádár
... Thyroid hormones regulate the TRH synthesis of hypophysiotropic neurons by negative feedback regulation. OATP1C1, the predominant thyroid hormone transporter molecule through the BBB is highly specific for thyroxine (T4), but not for triiodithyronine (T3), the active form of thyroid hormones. Theref ...
... Thyroid hormones regulate the TRH synthesis of hypophysiotropic neurons by negative feedback regulation. OATP1C1, the predominant thyroid hormone transporter molecule through the BBB is highly specific for thyroxine (T4), but not for triiodithyronine (T3), the active form of thyroid hormones. Theref ...
What is the function of the claustrum? - Christof Koch
... 1981a; Brand 1981; Braak & Braak 1982). The axons of these type I cells, after throwing off local collaterals, often leave the claustrum either medially or laterally (figure 4a). They are the principal cells of the claustrum in that they can both receive an input from the cortex and project back. Th ...
... 1981a; Brand 1981; Braak & Braak 1982). The axons of these type I cells, after throwing off local collaterals, often leave the claustrum either medially or laterally (figure 4a). They are the principal cells of the claustrum in that they can both receive an input from the cortex and project back. Th ...
Can You Smell That? Anatomy and Physiology of Smell
... Horizontal (dark) and Globose (light) basal cells: located near the basement membrane from which the other cell types arise ...
... Horizontal (dark) and Globose (light) basal cells: located near the basement membrane from which the other cell types arise ...
Kisspeptin Signaling Is Required for the Luteinizing Introduction of Males
... The introduction of a novel male stimulates the hypothalamic-pituitary-gonadal axis of female sheep during seasonal anestrus, leading to the resumption of follicle maturation and ovulation. How this pheromone cue activates pulsatile secretion of gonadotropin releasing hormone (GnRH)/luteinizing horm ...
... The introduction of a novel male stimulates the hypothalamic-pituitary-gonadal axis of female sheep during seasonal anestrus, leading to the resumption of follicle maturation and ovulation. How this pheromone cue activates pulsatile secretion of gonadotropin releasing hormone (GnRH)/luteinizing horm ...
Single unit and extracellular firing rate recordings in vivo
... (S)--fluoromethylhistidine blocked the arousal effect of montirelin in WT mice. We conclude, that direct excitation of rodent TMN neurons by TRH is receptor-mediated and demands activation of nonselective cation channels as well as electrogenic Na+/Ca2+ exchange. Our findings indicate a key role of ...
... (S)--fluoromethylhistidine blocked the arousal effect of montirelin in WT mice. We conclude, that direct excitation of rodent TMN neurons by TRH is receptor-mediated and demands activation of nonselective cation channels as well as electrogenic Na+/Ca2+ exchange. Our findings indicate a key role of ...
Intracellular and extracellular signatures of action potentials
... I would like to thank Richard Miles, whose work and encouragement brought me to join the scientific community of Paris. I am eternally grateful to Valérie Bercier who offered her gracious help when I needed it most and spent countless hours on reading my thesis and laboriously correcting all the En ...
... I would like to thank Richard Miles, whose work and encouragement brought me to join the scientific community of Paris. I am eternally grateful to Valérie Bercier who offered her gracious help when I needed it most and spent countless hours on reading my thesis and laboriously correcting all the En ...
Growth and Targeting of Subplate Axons and Establishment of Major
... and Galaburda, 1984). The laminar distribution of cortical projection neurons reflects this organizational scheme. Projections to subcortical structures arise only from layers 5 and 6: neurons in layer 6 send their axons to the thalamus; neurons in layer 5 project to multiple targets in the midbrain ...
... and Galaburda, 1984). The laminar distribution of cortical projection neurons reflects this organizational scheme. Projections to subcortical structures arise only from layers 5 and 6: neurons in layer 6 send their axons to the thalamus; neurons in layer 5 project to multiple targets in the midbrain ...
Organelle motility and metabolism in axons vs dendrites of cultured
... organelle motility, neurons were labeled with the mitochondrial vital dye rhodamine 123 (0.2 µg/ml) for 30 minutes at 37°C, washed once with HBSS, then returned to culture medium for immediate observa tion. For fluorescent images, a 50 W mercury lamp and a 1.0 neutral density filter were used. For ph ...
... organelle motility, neurons were labeled with the mitochondrial vital dye rhodamine 123 (0.2 µg/ml) for 30 minutes at 37°C, washed once with HBSS, then returned to culture medium for immediate observa tion. For fluorescent images, a 50 W mercury lamp and a 1.0 neutral density filter were used. For ph ...
Fig. 1
... normalized to the values obtained for a control antibody to correct for variation in the amount of total protein loaded. 2.5. Statistical analysis All experiments were repeated at least three times and the results are presented as the mean ± standard error of the mean. Statistical differences betwee ...
... normalized to the values obtained for a control antibody to correct for variation in the amount of total protein loaded. 2.5. Statistical analysis All experiments were repeated at least three times and the results are presented as the mean ± standard error of the mean. Statistical differences betwee ...
Axonally Synthesized ATF4 Transmits a Neurodegenerative Signal across Brain Regions Baleriola,
... Neurodegeneration Triggered by Axonal Exposure to Ab1-42 Application of Ab1-42 to axons did not increase axonal fragmentation or cell death within 24 hr, and after 48 hr of Ab1-42 exposure the number of TUNEL-positive neurons was significantly greater whereas axonal fragmentation was not induced (Fi ...
... Neurodegeneration Triggered by Axonal Exposure to Ab1-42 Application of Ab1-42 to axons did not increase axonal fragmentation or cell death within 24 hr, and after 48 hr of Ab1-42 exposure the number of TUNEL-positive neurons was significantly greater whereas axonal fragmentation was not induced (Fi ...
Print
... GYPGQV can directly activate PAR4 (143, 317). Mutation of the cleavage site prevents activation by thrombin and trypsin, but not by the synthetic peptide, which confirms the importance of proteolytic cleavage for receptor activation. C. Protease Binding to PARs Facilitates Cleavage and Activation Th ...
... GYPGQV can directly activate PAR4 (143, 317). Mutation of the cleavage site prevents activation by thrombin and trypsin, but not by the synthetic peptide, which confirms the importance of proteolytic cleavage for receptor activation. C. Protease Binding to PARs Facilitates Cleavage and Activation Th ...
Mechanisms of developmental neurite pruning
... For many years, it was known that nervous system development includes late regressive events. Indeed, about 50 % of murine neurons die during development and in early post-natal life [8]. One of the first studies to show that neuronal connections are eliminated during the normal course of developmen ...
... For many years, it was known that nervous system development includes late regressive events. Indeed, about 50 % of murine neurons die during development and in early post-natal life [8]. One of the first studies to show that neuronal connections are eliminated during the normal course of developmen ...
Downloadable Full Text - DSpace@MIT
... hypothalamus, mPFC, mediodorsal thalamic nucleus, and supraoculomotor central grey) expressed both fluorophores (Supplementary Fig. 11), suggesting that almost all of these neurons project solely to VTA/RMTg. As a positive control we injected one RV into VTA and the other into ventral pallidum and f ...
... hypothalamus, mPFC, mediodorsal thalamic nucleus, and supraoculomotor central grey) expressed both fluorophores (Supplementary Fig. 11), suggesting that almost all of these neurons project solely to VTA/RMTg. As a positive control we injected one RV into VTA and the other into ventral pallidum and f ...
Molecular and functional anatomy of the mouse olfactory epithelium
... ligand specificity, the restricted patterns of c-Fos induction suggests that low concentrations of odorous molecules activate only one or a few ORs. Studies on olfactory detection abilities of mice with zonal-restricted lesions in the olfactory epithelium show that loss of a zone has severe effects ...
... ligand specificity, the restricted patterns of c-Fos induction suggests that low concentrations of odorous molecules activate only one or a few ORs. Studies on olfactory detection abilities of mice with zonal-restricted lesions in the olfactory epithelium show that loss of a zone has severe effects ...
Print
... effects of these molecules, on how these lipid mediators are produced physiologically, and on the functional roles that they may serve. A major step was the discovery that depolarization-induced suppression of inhibition (DSI; or excitation, DSE), a type of short-term synaptic plasticity originally ...
... effects of these molecules, on how these lipid mediators are produced physiologically, and on the functional roles that they may serve. A major step was the discovery that depolarization-induced suppression of inhibition (DSI; or excitation, DSE), a type of short-term synaptic plasticity originally ...
Development of the brain stem in the rat. V. Thymidine‐radiographic
... 3H-thymidinefrom gestational day E l 2 and 13 (El2+ 13)until the day before parturition (E21+ 22) in order to label in their embryos the proliferating precursors of neurons. At 60 days of age the proportion of neurons generated (nolonger labeled) on specific embryonic days was determined quantitativ ...
... 3H-thymidinefrom gestational day E l 2 and 13 (El2+ 13)until the day before parturition (E21+ 22) in order to label in their embryos the proliferating precursors of neurons. At 60 days of age the proportion of neurons generated (nolonger labeled) on specific embryonic days was determined quantitativ ...
Chemical Nature of Synaptic Transmission in Vertebrates
... and related compounds. In general, the parasympathetic system acts on its effector organs by muscarinic transmission, whereas nicotinic actions are seen characteristically at the skeletal neuromuscular junction and in autonomic ganglia; but ACh may act in both ways on the same cell, as in sympatheti ...
... and related compounds. In general, the parasympathetic system acts on its effector organs by muscarinic transmission, whereas nicotinic actions are seen characteristically at the skeletal neuromuscular junction and in autonomic ganglia; but ACh may act in both ways on the same cell, as in sympatheti ...
The Development of Ocular Dominance Columns
... deprivation was to change the relative sizes of the patches of inputs to visual cortex serving the two eyes, while keeping the repeat distance the same (figure 3) (Hubel, Wiesel, and LeVay, 1977; Shatz and Stryker, 1978). But the reason for such a sensitive period in early life, in which such small ...
... deprivation was to change the relative sizes of the patches of inputs to visual cortex serving the two eyes, while keeping the repeat distance the same (figure 3) (Hubel, Wiesel, and LeVay, 1977; Shatz and Stryker, 1978). But the reason for such a sensitive period in early life, in which such small ...
the role of zinc in the pathogenesis and treatment of central nervous
... organism is an antioxidative protection (6, 7). Zinc decreases ROS generation by several mechanisms. Firstly, the zinc antioxidative effect occurs through activity of zinc dependent enzyme, superoxide dismutase (1). Secondly, zinc metallothioneins (MT) can bind and neutralize ROS due to their sulfhy ...
... organism is an antioxidative protection (6, 7). Zinc decreases ROS generation by several mechanisms. Firstly, the zinc antioxidative effect occurs through activity of zinc dependent enzyme, superoxide dismutase (1). Secondly, zinc metallothioneins (MT) can bind and neutralize ROS due to their sulfhy ...
Blueprint for exam make sure you know directional terminology be
... be able to give a description of the function of epithelial tissue be able to describe where epithelial tissue is found be able to describe all types of epithelial tissue, their function, and location be able to describe the characteristics of epithelial tissue (including the apical projections) be ...
... be able to give a description of the function of epithelial tissue be able to describe where epithelial tissue is found be able to describe all types of epithelial tissue, their function, and location be able to describe the characteristics of epithelial tissue (including the apical projections) be ...
mGluR-dependent persistent firing in entorhinal cortex layer III neurons SYNAPTIC MECHANISMS Motoharu Yoshida,
... antagonist scopolamine in humans (Schon et al., 2005), and scopolamine has been shown to impair performance of delayed matching tasks (Penetar & McDonough, 1983; Robbins et al., 1997; Koller et al., 2003). On the other hand, recent in vivo findings have shown an involvement of group I metabotropic gl ...
... antagonist scopolamine in humans (Schon et al., 2005), and scopolamine has been shown to impair performance of delayed matching tasks (Penetar & McDonough, 1983; Robbins et al., 1997; Koller et al., 2003). On the other hand, recent in vivo findings have shown an involvement of group I metabotropic gl ...
Resonance properties of different neuronal populations in the
... Delta waves are high amplitude brain wave with a frequency of oscillation between 0.5-4 Hz, and are in mature mammals usually associated with slow-wave sleep (SWS), also known as non-REM (rapid eye movement) sleep (Sejnowski and Destexhe, 2000). However, they are a dominant brain-wave pattern in inf ...
... Delta waves are high amplitude brain wave with a frequency of oscillation between 0.5-4 Hz, and are in mature mammals usually associated with slow-wave sleep (SWS), also known as non-REM (rapid eye movement) sleep (Sejnowski and Destexhe, 2000). However, they are a dominant brain-wave pattern in inf ...
Subventricular zone
The subventricular zone (SVZ) is a paired brain structure situated throughout the lateral walls of the lateral ventricles. It is composed of four distinct layers of variable thickness and cell density, as well as cellular composition. Along with the dentate gyrus of the hippocampus, the SVZ is one of two places where neurogenesis has been found to occur in the adult mammalian brain.