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... variation in reported CsA sensitivity was explained by the observation of Bambrick et al. [47] that only astrocytic (but not neuronal) mitochondria displayed a CsA-sensitive Ca2+ accumulation capacity. In addition permeabilized astrocytes could accumulate more Ca2+ than permeabilized granule neurons ...
... variation in reported CsA sensitivity was explained by the observation of Bambrick et al. [47] that only astrocytic (but not neuronal) mitochondria displayed a CsA-sensitive Ca2+ accumulation capacity. In addition permeabilized astrocytes could accumulate more Ca2+ than permeabilized granule neurons ...
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... regulatory factors such as FX, protease nexin-1 (PN-1), AT III and thrombin-activated receptors have been identified in these specimens, indicating a potential role of thrombin in the CNS [13]. Prothrombin has been found on neuronal cells and astrocytes via mRNA measurement in rat and human nervous ...
... regulatory factors such as FX, protease nexin-1 (PN-1), AT III and thrombin-activated receptors have been identified in these specimens, indicating a potential role of thrombin in the CNS [13]. Prothrombin has been found on neuronal cells and astrocytes via mRNA measurement in rat and human nervous ...
Thalamocortical neuron loss and localized astrocytosis in the Cln3
... the novel finding of a loss of sensory relay thalamic neurons. These affected mice also exhibited profound astrocytic reactions that were most pronounced in the neocortex and thalamus, but diminished in other brain regions. These data provide the first direct evidence for neurodegenerative and react ...
... the novel finding of a loss of sensory relay thalamic neurons. These affected mice also exhibited profound astrocytic reactions that were most pronounced in the neocortex and thalamus, but diminished in other brain regions. These data provide the first direct evidence for neurodegenerative and react ...
Here follows a list of recently published papers
... http://t.co/avwjFHZA7z Deficiency of prion protein: impaired autophagic flux in neurons http://bit.ly/1mFLiM3 CA3 size predicts the precision of memory recall http://bit.ly/1mukcG9 " A Role for Tac2, NkB, and Nk3 Receptor in Normal and Dysregulated Fear Memory Consolidation http://www.cell.com/neuro ...
... http://t.co/avwjFHZA7z Deficiency of prion protein: impaired autophagic flux in neurons http://bit.ly/1mFLiM3 CA3 size predicts the precision of memory recall http://bit.ly/1mukcG9 " A Role for Tac2, NkB, and Nk3 Receptor in Normal and Dysregulated Fear Memory Consolidation http://www.cell.com/neuro ...
The supramammillary area: its organization, functions
... particularly memory. We argue, on several different grounds, therefore, that its modulation of telencephalic activity is fundamental to cognitive–emotional interactions. This claim is subject to two caveats. First, we are claiming only a modulatory role for SuM. It is likely to pace information arou ...
... particularly memory. We argue, on several different grounds, therefore, that its modulation of telencephalic activity is fundamental to cognitive–emotional interactions. This claim is subject to two caveats. First, we are claiming only a modulatory role for SuM. It is likely to pace information arou ...
Propofol Inhibits Neuronal Firing Activities in the Caudal
... Some neuronal firings are of high frequency and some are of low frequency. This indicates that different types of neurons exist in the CVLM and possibly display different firing patterns or functions. For example, much evidence demonstrates that projecting neurons in the CVLM can transmit electrical ...
... Some neuronal firings are of high frequency and some are of low frequency. This indicates that different types of neurons exist in the CVLM and possibly display different firing patterns or functions. For example, much evidence demonstrates that projecting neurons in the CVLM can transmit electrical ...
to the Proceedings
... Despite key progress in the understanding of synapse formation, synaptic transmission and plasticity, much remains to be determined with respect to the molecular and cellular mechanisms that could lead to therapies for brain diseases. To develop effective treatments, deciphering the synaptic functio ...
... Despite key progress in the understanding of synapse formation, synaptic transmission and plasticity, much remains to be determined with respect to the molecular and cellular mechanisms that could lead to therapies for brain diseases. To develop effective treatments, deciphering the synaptic functio ...
Enteric Glia - Department of Physiology
... “second brain,” known as the enteric nervous system (ENS), resides within the walls of the intestines and controls the ongoing activities of the gastrointestinal tract. The entire circuitry of the ENS is embedded in the gut wall and consists of aggregates of neurons and glia called enteric ganglia t ...
... “second brain,” known as the enteric nervous system (ENS), resides within the walls of the intestines and controls the ongoing activities of the gastrointestinal tract. The entire circuitry of the ENS is embedded in the gut wall and consists of aggregates of neurons and glia called enteric ganglia t ...
Biophysics of Extracellular Action Potentials
... I compared constraining a compartmental model to fit the EAP with matching the intracellular action potential (IAP). I find that the IAP method underconstrains the parameters. The distinguishing characteristics of the EAP constrain the parameters and are fairly invariant to electrode position and ce ...
... I compared constraining a compartmental model to fit the EAP with matching the intracellular action potential (IAP). I find that the IAP method underconstrains the parameters. The distinguishing characteristics of the EAP constrain the parameters and are fairly invariant to electrode position and ce ...
[Ca2+]c dynamics in spontaneously firing dopamine neurons of the
... maintaining the functions of dopamine neurons. However, how each glutamate receptor is activated and cooperatively contributes to the [Ca2+]c dynamics is not clear in SNc dopamine neurons. This is partly due to the specific situation of the neurons, which always exist within the brain tissue and so ...
... maintaining the functions of dopamine neurons. However, how each glutamate receptor is activated and cooperatively contributes to the [Ca2+]c dynamics is not clear in SNc dopamine neurons. This is partly due to the specific situation of the neurons, which always exist within the brain tissue and so ...
Circadian clocks in crustaceans: identified neuronal and cellular systems
... from in vitro experiments with specific ablated tissues, an approach providing important additional sources of information for testing whether tissues or organs have indeed autonomous circadian activities (23, 54, 85). As ablation or loss of function and in vitro tissue culturing experiments only al ...
... from in vitro experiments with specific ablated tissues, an approach providing important additional sources of information for testing whether tissues or organs have indeed autonomous circadian activities (23, 54, 85). As ablation or loss of function and in vitro tissue culturing experiments only al ...
Functional Heterogeneity in the Bed Nucleus of the Stria Terminalis
... the oval nucleus (Sakanaka et al., 1987; Phelix and Paull, 1990), which also express a fast inwardly rectifying K ⫹ conductance (known as Type III cells; Fig. 3C) (Dabrowska et al., 2013a; but see Silberman et al., 2013). It should be noted that the number of CRF-positive BNST neurons is higher in r ...
... the oval nucleus (Sakanaka et al., 1987; Phelix and Paull, 1990), which also express a fast inwardly rectifying K ⫹ conductance (known as Type III cells; Fig. 3C) (Dabrowska et al., 2013a; but see Silberman et al., 2013). It should be noted that the number of CRF-positive BNST neurons is higher in r ...
Might the olfactory bulb be an origin of olfactory auras in focal
... Olfactory auras or phantosmia are false perceptions of odours, usually unpleasant and unprovoked by ambient surroundings. They are epileptic phenomena associated with focal complex seizures of mesial temporal lobe origin. They occur as isolated phenomena, usually lasting seconds or a few minutes, or ...
... Olfactory auras or phantosmia are false perceptions of odours, usually unpleasant and unprovoked by ambient surroundings. They are epileptic phenomena associated with focal complex seizures of mesial temporal lobe origin. They occur as isolated phenomena, usually lasting seconds or a few minutes, or ...
Chemical Transmitters and Modulation of Sleep
... wlio tauglit me tlie meanino ofpatience ana e~ce{fent researcli. ...
... wlio tauglit me tlie meanino ofpatience ana e~ce{fent researcli. ...
Input-specific control of reward and aversion in the ventral tegmental
... differentially modulate such circuits. Here we show that, because of differences in synaptic connectivity, activation of inputs to the VTA from the laterodorsal tegmentum and the lateral habenula elicit reward and aversion in mice, respectively. Laterodorsal tegmentum neurons preferentially synapse ...
... differentially modulate such circuits. Here we show that, because of differences in synaptic connectivity, activation of inputs to the VTA from the laterodorsal tegmentum and the lateral habenula elicit reward and aversion in mice, respectively. Laterodorsal tegmentum neurons preferentially synapse ...
Processing of Interaural Intensity Differences in the LSO: Role of
... units during the course of the experiments as described previously (Park and Pollak 1993). Spikes were fed to a window discriminator and the output of the discriminator was fed to the computer. When a unit was encountered, its characteristic frequency (the frequency to which the neuron was most sens ...
... units during the course of the experiments as described previously (Park and Pollak 1993). Spikes were fed to a window discriminator and the output of the discriminator was fed to the computer. When a unit was encountered, its characteristic frequency (the frequency to which the neuron was most sens ...
Sample
... 27) What is the term used to describe the rounded areas on the ends of the axon terminals? A) synaptic vesicles B) axons C) dendrites D) synaptic knobs Correct: Correct. Synaptic knobs are located at the tip of each axon terminal. Incorrect: Incorrect. Synaptic vesicles are structures within the syn ...
... 27) What is the term used to describe the rounded areas on the ends of the axon terminals? A) synaptic vesicles B) axons C) dendrites D) synaptic knobs Correct: Correct. Synaptic knobs are located at the tip of each axon terminal. Incorrect: Incorrect. Synaptic vesicles are structures within the syn ...
Selective Loss of Calcitonin Gene–Related Peptide
... numbers of immunoreactive substance P and calcitonin gene–related peptide (CGRP) dorsal root ganglion (DRG) cell bodies were estimated in diabetic and nondiabetic BALB/C (p75ⴙ/ⴙ) and p75 receptor knockout (p75ⴚ/ⴚ) mice with unilateral sciatic nerve crush. The total numbers of immunoreactive substanc ...
... numbers of immunoreactive substance P and calcitonin gene–related peptide (CGRP) dorsal root ganglion (DRG) cell bodies were estimated in diabetic and nondiabetic BALB/C (p75ⴙ/ⴙ) and p75 receptor knockout (p75ⴚ/ⴚ) mice with unilateral sciatic nerve crush. The total numbers of immunoreactive substanc ...
Kobayashi S, Kawagoe R, Takikawa Y, Koizumi M, Sakagami M
... related to the task. We analyzed only trials in which the monkey made a correct response. Single-unit activity was classified based on 2-way analysis of variance (CUE-dir · RWD-dir, P < 0.01). Activity with and only with a significant main effect of the cue direction was defined as ‘‘CUE-dir type’’. ...
... related to the task. We analyzed only trials in which the monkey made a correct response. Single-unit activity was classified based on 2-way analysis of variance (CUE-dir · RWD-dir, P < 0.01). Activity with and only with a significant main effect of the cue direction was defined as ‘‘CUE-dir type’’. ...
Gamma Oscillations in the Hippocampus
... Role of Inhibition In a system that relies on fast temporal correlations to link interactions among cells, the activity of most cells in the network at any given time must be suppressed because otherwise many cells would fire near synchronously just by chance (87). In accordance with this idea, many ...
... Role of Inhibition In a system that relies on fast temporal correlations to link interactions among cells, the activity of most cells in the network at any given time must be suppressed because otherwise many cells would fire near synchronously just by chance (87). In accordance with this idea, many ...
B-Lymphocyte-Mediated Delayed Cognitive Impairment following
... stroke are at increased risk of developing dementia, and approximately one-third will eventually suffer from vascular dementia (Barba et al., 2000; Leys et al., 2005; Béjot et al., 2011). In many of these patients, dementia might be caused by an associated comorbidity, but even after controlling fo ...
... stroke are at increased risk of developing dementia, and approximately one-third will eventually suffer from vascular dementia (Barba et al., 2000; Leys et al., 2005; Béjot et al., 2011). In many of these patients, dementia might be caused by an associated comorbidity, but even after controlling fo ...
Anatomy and Physiology of Smell
... Olfactory receptor genes account for ~1% of all expressed genes of the human genome Largest known vertebrate gene family Receptors not randomly distributed but confined to one of several nonoverlapping striplike zones Each cell is responsive to a wide, but circumscribed, range of stimuli Olfactory ...
... Olfactory receptor genes account for ~1% of all expressed genes of the human genome Largest known vertebrate gene family Receptors not randomly distributed but confined to one of several nonoverlapping striplike zones Each cell is responsive to a wide, but circumscribed, range of stimuli Olfactory ...
The Classical Complement Cascade Mediates
... C1q KO mice had a significantly higher percentage of overlapping projections, independent of threshold (Figure 4B). The lack of a phenotype at P5 suggests that refinement defects in the P10 C1q KO mice are not due to early defects in axonal path finding or targeting. In addition, this segregation ph ...
... C1q KO mice had a significantly higher percentage of overlapping projections, independent of threshold (Figure 4B). The lack of a phenotype at P5 suggests that refinement defects in the P10 C1q KO mice are not due to early defects in axonal path finding or targeting. In addition, this segregation ph ...
Subventricular zone
The subventricular zone (SVZ) is a paired brain structure situated throughout the lateral walls of the lateral ventricles. It is composed of four distinct layers of variable thickness and cell density, as well as cellular composition. Along with the dentate gyrus of the hippocampus, the SVZ is one of two places where neurogenesis has been found to occur in the adult mammalian brain.