Structure and Function of Mammalian Ribosomes
... In our studies we concentrated our efforts on developing methods for the preparation of high yields of subunits, the majority of which are structurally and functionally intact. This then allows us to correlate function more quantitatively with structure. We wanted to minimize the harshness of the co ...
... In our studies we concentrated our efforts on developing methods for the preparation of high yields of subunits, the majority of which are structurally and functionally intact. This then allows us to correlate function more quantitatively with structure. We wanted to minimize the harshness of the co ...
Evolution of the Insulin Receptor Family and
... vertebrates, 3 distinct receptors that can bind with highaffinity insulin and the IGF were described based on differences in primary structure and function: the IR (Ebina et al. 1985; Ullrich et al. 1985), the type 1 IGF receptor (IGF1R) (Ullrich et al. 1986), and the type 2 IGF receptor (IGF2R) (Mo ...
... vertebrates, 3 distinct receptors that can bind with highaffinity insulin and the IGF were described based on differences in primary structure and function: the IR (Ebina et al. 1985; Ullrich et al. 1985), the type 1 IGF receptor (IGF1R) (Ullrich et al. 1986), and the type 2 IGF receptor (IGF2R) (Mo ...
Amino Acid Phylogeny
... organisms that appear to have few physical similarities may have similar sequences of amino acids in their proteins and be closely related through evolution. Many researchers believe that the greater the similarity in the amino-acid sequences of two organisms, the more closely related they are in an ...
... organisms that appear to have few physical similarities may have similar sequences of amino acids in their proteins and be closely related through evolution. Many researchers believe that the greater the similarity in the amino-acid sequences of two organisms, the more closely related they are in an ...
MD1-103 Protein Stability Combo Kit
... RUBIC Buffer and RUBIC Additive Screens have been designed and developed by Stephane Boivin and Rob Meijers at the EMBL Hamburg and is manufactured exclusively under license by Molecular Dimensions Limited. Limited Use and Restrictions: Products sold by Molecular Dimensions Ltd. or its affiliates or ...
... RUBIC Buffer and RUBIC Additive Screens have been designed and developed by Stephane Boivin and Rob Meijers at the EMBL Hamburg and is manufactured exclusively under license by Molecular Dimensions Limited. Limited Use and Restrictions: Products sold by Molecular Dimensions Ltd. or its affiliates or ...
שקופית 1 - Tel Aviv University
... • As many as possible, as long as the MSA looks good (next week…) ...
... • As many as possible, as long as the MSA looks good (next week…) ...
MedBiochem Exam 1, 1998
... 16. The immediate products of oxidation of one mole of glucose 6phosphate through the oxidative portion of the pentose phosphate pathway are A. one mole of ribulose 5-phosphate, one mole of carbon dioxide and two moles of NAD. B. one mole of ribose 5-phosphate, one mole of carbon dioxide and two mol ...
... 16. The immediate products of oxidation of one mole of glucose 6phosphate through the oxidative portion of the pentose phosphate pathway are A. one mole of ribulose 5-phosphate, one mole of carbon dioxide and two moles of NAD. B. one mole of ribose 5-phosphate, one mole of carbon dioxide and two mol ...
Maintaining Ideal Yeast Health: Nutrients Yeast Need
... particles that sedimented to its bottom • Particle size is a likely determinant of the particle’s ability to be an effective CO2 nucleator • The more porous a particle is, the most efficient it is as a nucleation site • Soy flour may be ruled out due to allergen issues ...
... particles that sedimented to its bottom • Particle size is a likely determinant of the particle’s ability to be an effective CO2 nucleator • The more porous a particle is, the most efficient it is as a nucleation site • Soy flour may be ruled out due to allergen issues ...
The Antibiotic Cerulenin, a Novel Tool for Biochemistry as an
... against infectious diseases and for accelerating their growth. They are also used as food additives to retain freshness for an extended period. The usefulness of antibiotics is not limited only to our daily needs, but also encompasses our research interests: they offer us remarkable experimental dev ...
... against infectious diseases and for accelerating their growth. They are also used as food additives to retain freshness for an extended period. The usefulness of antibiotics is not limited only to our daily needs, but also encompasses our research interests: they offer us remarkable experimental dev ...
Influence of hepatic ammonia removal on ureagenesis, amino acid
... precursors, mitochondrial NH 3 and cytosolic aspartate. Blood free amino acids are, together with NH 3, the only N-substrates extracted by the liver in amounts sufficient to mantain the rates of ureagenesis observed in ruminants in vivo (Huntington, 1989; Reynolds et al. 1991; Lobley et al. 1995). I ...
... precursors, mitochondrial NH 3 and cytosolic aspartate. Blood free amino acids are, together with NH 3, the only N-substrates extracted by the liver in amounts sufficient to mantain the rates of ureagenesis observed in ruminants in vivo (Huntington, 1989; Reynolds et al. 1991; Lobley et al. 1995). I ...
Cloning and sequence analysis of cnaA gene encoding the catalytic
... to study its function in detail. While earlier reports of calcineurin A from ¢lamentous fungi suggested its requirement for hyphal growth and cell cycle regulation [5,6], a putative role of this protein phosphatase in sporulation, salt stress response and the alkaline pH-mediated signal transduction ...
... to study its function in detail. While earlier reports of calcineurin A from ¢lamentous fungi suggested its requirement for hyphal growth and cell cycle regulation [5,6], a putative role of this protein phosphatase in sporulation, salt stress response and the alkaline pH-mediated signal transduction ...
The Effect of a Limited Supply of Phenylalanine, Threonine, or
... body. Arginine (Arg), histidine (His), isoleucine (Ile), leucine (Leu), lysine (Lys), methionine (Met), phenylalanine (Phe), threonine (Thr), tryptophan (Trp), and valine (Val) have been recognized as EAA for dairy cows (Schwab et al., 1975). The NEAA can be synthesized by the body; thus, there is n ...
... body. Arginine (Arg), histidine (His), isoleucine (Ile), leucine (Leu), lysine (Lys), methionine (Met), phenylalanine (Phe), threonine (Thr), tryptophan (Trp), and valine (Val) have been recognized as EAA for dairy cows (Schwab et al., 1975). The NEAA can be synthesized by the body; thus, there is n ...
A 5000-Fold Increase in the Specificity of a Bacterial
... the nucleophile, is well documented [16–18]. This mechanism results in a biphasic dependence of the rate of hydrolysis upon the pKa of the leaving group of the substrate (Fig. 2). For OPs with leaving groups that have pKa values of ,8.0 or lower the kcat/KM for the reaction is near the diffusion lim ...
... the nucleophile, is well documented [16–18]. This mechanism results in a biphasic dependence of the rate of hydrolysis upon the pKa of the leaving group of the substrate (Fig. 2). For OPs with leaving groups that have pKa values of ,8.0 or lower the kcat/KM for the reaction is near the diffusion lim ...
D-lactic acidosis: Turning sugar into acids in the gastrointestinal tract
... usually pose an acid-base threat because the quantity ingested is colonic mucosal cells [21, 22]. Should the metabolic work of these not large enough to exceed the capacity of the host to remove mucosal cells (ions pumping for the most part) remain high at a them by metabolic means. In addition, the ...
... usually pose an acid-base threat because the quantity ingested is colonic mucosal cells [21, 22]. Should the metabolic work of these not large enough to exceed the capacity of the host to remove mucosal cells (ions pumping for the most part) remain high at a them by metabolic means. In addition, the ...
Write on zinc fingers
... The majority of engineered zinc finger arrays are based on the zinc finger domain of the murine transcription factor Zif268, although some groups have used zinc finger arrays based on the human transcription factor SP1. Zif268 has three individual zinc finger motifs that collectively bind a 9 bp seq ...
... The majority of engineered zinc finger arrays are based on the zinc finger domain of the murine transcription factor Zif268, although some groups have used zinc finger arrays based on the human transcription factor SP1. Zif268 has three individual zinc finger motifs that collectively bind a 9 bp seq ...
IDENTIFICATION AND CHARACTERIZATION OF SYNAPTONEMAL
... without heterologous synapsis or synaptic adjustment, to form a complete set of entirely synapsed bivalents, have a better chance of producing viable meiotic products than cells which do not (e.g. De Boer and De Jong, 1989). According to this hypothesis mutation of genes encoding structural componen ...
... without heterologous synapsis or synaptic adjustment, to form a complete set of entirely synapsed bivalents, have a better chance of producing viable meiotic products than cells which do not (e.g. De Boer and De Jong, 1989). According to this hypothesis mutation of genes encoding structural componen ...
Engineering subunit association of multisubunit proteins
... soluble dimeric streptavidin in the presence of biotin. There are many examples of the successful production of individual subunits of multisubunit proteins using recombinant DNA technology. However, in most of these successful cases, each subunit functions independently of the other subunits in its ...
... soluble dimeric streptavidin in the presence of biotin. There are many examples of the successful production of individual subunits of multisubunit proteins using recombinant DNA technology. However, in most of these successful cases, each subunit functions independently of the other subunits in its ...
Gluconeogenesis
... starvation is mainly amino acid catabolism. Some amino acids are catabolized to pyruvate, oxaloacetate, or precursors of these. Muscle proteins may break down to supply amino acids. These are transported to liver where they are deaminated and converted to gluconeogenesis inputs. Glycerol, derived fr ...
... starvation is mainly amino acid catabolism. Some amino acids are catabolized to pyruvate, oxaloacetate, or precursors of these. Muscle proteins may break down to supply amino acids. These are transported to liver where they are deaminated and converted to gluconeogenesis inputs. Glycerol, derived fr ...
Introduction to Nutrition and Metabolism, Third Edition
... muscles, whether they are ‘working’ or not. These processes require a metabolic energy source. Less obviously, there is also a requirement for energy for the wide variety of biochemical reactions occurring all the time in the body: laying down reserves of fat and carbohydrate (section 5.6); turnover ...
... muscles, whether they are ‘working’ or not. These processes require a metabolic energy source. Less obviously, there is also a requirement for energy for the wide variety of biochemical reactions occurring all the time in the body: laying down reserves of fat and carbohydrate (section 5.6); turnover ...
Module 2 Biochemical bases of proliferation, intercellular
... 64. Who synthesized uric acid artificially from glycine and urea in 1882: A. German scientist Veller B. German scientist Fisher C. Polish-Russian scientist Nenskiy D. Austrian physiologist Maresh E. * Ukrainian scientist I. Horbachevskiy 65. Why constant excessive consumption of meat and glandular t ...
... 64. Who synthesized uric acid artificially from glycine and urea in 1882: A. German scientist Veller B. German scientist Fisher C. Polish-Russian scientist Nenskiy D. Austrian physiologist Maresh E. * Ukrainian scientist I. Horbachevskiy 65. Why constant excessive consumption of meat and glandular t ...
FIST/HIPK3: a Fas/FADD-interacting Serine/Threonine Kinase that
... An alternative pathway of Fas signaling involves the Fasbinding protein Daxx (3), although these data have been recently challenged (4). It was proposed that upon Fas activation, Daxx interacts with and activates a mitogen-activated protein kinase kinase kinase termed ASK1 (apoptosis signal-regulati ...
... An alternative pathway of Fas signaling involves the Fasbinding protein Daxx (3), although these data have been recently challenged (4). It was proposed that upon Fas activation, Daxx interacts with and activates a mitogen-activated protein kinase kinase kinase termed ASK1 (apoptosis signal-regulati ...
Combined fluorescence and electrochemical investigation on the
... result is displayed by a plot of A/A0 as a function of the fatty acid concentration, where A0 is the fluorescence of the probe/HSA complex before addition of the fatty acid, and A is the fluorescence after addition of the fatty acid at a certain concentration. Titration of C8 against HSA with the drug ...
... result is displayed by a plot of A/A0 as a function of the fatty acid concentration, where A0 is the fluorescence of the probe/HSA complex before addition of the fatty acid, and A is the fluorescence after addition of the fatty acid at a certain concentration. Titration of C8 against HSA with the drug ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.