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Biomolecules
Biomolecules

... •A fat (mostly saturated) is solid at room temp., while an oil (mostly unsaturated) is liquid at room temp. ...
biological_molecules_facts
biological_molecules_facts

... The linking bond between two monosaccharides is a glycosidic link. Maltose is formed from two glucose molecules. Sucrose is a non-reducing sugar. It must be hydrolysed with warm hydrochloric acid before it gives a positive reducing sugar test. Sucrose is formed from a glucose and a fructose. Starch ...
Protien Synthesis
Protien Synthesis

... Transfers amino acids from the cytoplasm to the ...
Bioinformatics
Bioinformatics

... • DNA, protein sequence – DNA: Purine/Pyrimidine – AAs: small, hydrophobic, aromatic, polar – Variants: SNPs, Indels, Alt Splicing ...
Pro Synth Review
Pro Synth Review

... -­  What  is  mRNA?   mRNA  is  a  single  stranded  copy  of  a  gene   ...
Molecules of Life
Molecules of Life

... Proteins • Protein structure: – The sequence of amino acids within the protein is called the primary structure. – Any folding of the primary chain structure is called the secondary structure. – Globular shapes are the tertiary structure of a protein. – When more than one polypeptide chain composes ...
Chapter 14 Proteins
Chapter 14 Proteins

... ◦ The polypeptide backbone is extended in a zigzag structure resembling a series of pleats. ◦ The six atoms of each peptide bond of a b-pleated sheet lie in the same plane. ◦ The C=O and N-H groups of the peptide bonds from adjacent chains point toward each other and are in the same plane so that hy ...
7.5 Proteins - HS Biology IB
7.5 Proteins - HS Biology IB

... IB Question: Distinguish between fibrous and globular proteins with reference to one example of each protein type. [6] fibrous proteins are strands/sheets whereas globular proteins are rounded; fibrous proteins (usually) insoluble whereas globular proteins (usually) soluble; globular more sensitive ...
bio98a_l04
bio98a_l04

... What fraction of the 280 nm photons have not been absorbed after passing through 1 cm of this sample? Abs = log10 Io/I = -log10 I/Io or ...
Psi-blast
Psi-blast

... known proteins that have a common function such as DNA binding (red dots), and in addition, a separate set of proteins that are known not to bind DNA (blue dots) ...
Van der Waals bonds
Van der Waals bonds

... • Several proteins are cleaved into smaller proteins or peptides following translation. For example, the enkephalins are small peptides which are derived from proteins in this manner . • Active enzymes are sometimes formed by cleaving a larger protein precursor. Often, this serves to protect the cel ...
Protein Synthesis
Protein Synthesis

... Review:Protein structureThe sequence or order of amino acids in a protein and hence protein function are determined by the genetic code and assembled by rRNA (ribosomes). -primary structure=order of amino acids -secondary structure is the shape of the polypeptide-alpha helix or beta sheet -tertiary ...
Structure Reveals How Cells `Sugar
Structure Reveals How Cells `Sugar

... scientists better understand a variety of diseases that result when the process goes awry. The research will appear in the March 12, 2008, issue of the journal Structure. "Proteins perform their functions by interacting at their surfaces with other molecules. So you can imagine that adding or removi ...
2013 version with answers.
2013 version with answers.

... PDB to find homolog (or its own structure if Murphy is on vacation). Use homology modelling to get structure. Find nice stretchy at surface that is a bit extended. Use software that predicts antigenicity for aa types to find best stretch. Inject this stretch in a rabbit and hope that antibodies will ...
Protein Structure - CS
Protein Structure - CS

... Protein Folds: sequential, spatial and topological arrangement of secondary structures ...
Proteins are biopolymers construced from similar building blocks
Proteins are biopolymers construced from similar building blocks

... the fact that the native structure is only stable in a limited pressure-temperature range [1]. This fact can be described theoretically by the so-called elliptic phase diagram [2]. The pressure induced changes in proteins have clearly nonlinear character. The simplest approach is to divide the press ...
Protein Structure
Protein Structure

... Have a right-handed twist! ...
Amino Acids 2
Amino Acids 2

... ◦ Arising from a brief shift of orbital electrons to one side of one atom or molecule, creating a similar shift in adjacent atoms or molecules. ...
Enzyme Biosinthess
Enzyme Biosinthess

... is bound during termination. Proteins called release factors participate in termination ...
Relationship between mutation and resistance to fluoroquinolones
Relationship between mutation and resistance to fluoroquinolones

... developmental processes. Generally, proteins are classified according to certain patterns or motifs in their basic components, the amino acids, or structures that are formed due to specific interactions between the amino acids. Characteristically, the bHLH proteins feature a stretch of basic amino a ...
Carbohydrates
Carbohydrates

...  Cholesterol = Helps maintain the fluidity of the membrane Protein  Remove the water from our cells and what’s left is mostly protein!  Determines the structure and function of an organism.  STRUCTURE  20 different amino acids - Functional groups - carboxyl group at one end (C terminus); amino ...
Four Types of Organic Molecules
Four Types of Organic Molecules

... Built in cell membrane. Transmits signals to the inside of the cell A protein can have four levels of structure 1. The _______________________________ of a protein is its unique amino acid sequence 2. Protein ____________________________ results from coiling or folding of the polypeptide held by hyd ...
BCBT100 Biochemistry of Food Study Guide
BCBT100 Biochemistry of Food Study Guide

... (http://www.queenoflub.com/biochem/terms.html).                  I  think  it  will  be  very  helpful  if  you  can  understand  more  than  the  vocabulary.      The  best  way  to  prepare  is  to  look  at  each  bullet   ...
Some General Information on CD of Proteins
Some General Information on CD of Proteins

... determined by analyzing its far-UV CD spectrum as a sum of fractional multiples of such reference spectra for each structural type. (e.g. For an alpha helical protein with increasing amounts of random coil present, the 222 nm minimum becomes shallower and the 208 nm minimum moves to lower wavelength ...
Catalogue Number CTK-611 Synonyms TFF
Catalogue Number CTK-611 Synonyms TFF

... TFF-2, Spasmolytic polypeptide, Spasmolysin, SML1, Trefoil factor 2, SP, TFF2. Proteins of the TFF family are characterized by obtaining a minimum of 1 copy of the trefoil motif, a 40-amino acid domain that contains 3 conserved disulfides. Trefoil Factors are stable secretory proteins expressed in g ...
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Protein structure prediction



Protein structure prediction is the prediction of the three-dimensional structure of a protein from its amino acid sequence — that is, the prediction of its folding and its secondary, tertiary, and quaternary structure from its primary structure. Structure prediction is fundamentally different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry; it is highly important in medicine (for example, in drug design) and biotechnology (for example, in the design of novel enzymes). Every two years, the performance of current methods is assessed in the CASP experiment (Critical Assessment of Techniques for Protein Structure Prediction). A continuous evaluation of protein structure prediction web servers is performed by the community project CAMEO3D.
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