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Part I: To Transcribe! In previous lessons, you`ve learned the
Part I: To Transcribe! In previous lessons, you`ve learned the

... stored in segments called genes. A gene is a specific sequence of nucleotides in a strand of DNA that codes for a specific sequence of amino acids. The amino acids form chains that make a certain protein depending on the order of the nitrogen bases. Just like 26 letters of the alphabet make words, 2 ...
Chapter 30
Chapter 30

... • Sequence elements in each tRNA are recognized by its specific synthetase including • 1) One or more of 3 bases in acceptor stem • 2) Base at position 73 “Discriminator base” • (3) In many, at least one anticodon base ...
BIO.2
BIO.2

2. Organic Compounds and the Four Biomolec
2. Organic Compounds and the Four Biomolec

... phosphate, and a base. The sugar, ribose in RNA and deoxyribose in DNA, contain 5 carbons. They differ only in that an –OH group in ribose is replaced by a –H in DNA. The main energy-carrying molecule in the cell is ATP. ATP is an RNA nucleotide with 3 phosphate groups attached to it in a chain. The ...
HSproteinsynth
HSproteinsynth

... ·The DNA strand in E. coli contains about 4 million base pairs, and these base pairs are organized into about 1,000 genes. A gene is simply a template for a protein, and often these proteins are enzymes. ...
From Gene to Protein Genes code for... Proteins RNAs Remember
From Gene to Protein Genes code for... Proteins RNAs Remember

... mRNA transcript is brought to the ribosome Initiation = the rRNA, mRNA transcript, and tRNA carrying methionine bind together Elongation = amino acids are added one by one to create the polypeptide Termination = when a stop codon is reached on the mRNA ...
Genetic aspects of Multiple Sclerosis Boon, Maartje
Genetic aspects of Multiple Sclerosis Boon, Maartje

... pentose sugar and a phosphate group. The bases are adenine (A), thymine (T), uracil (U), guanine (G) and cytosine (C), the pentose sugars deoxyribose and ribose. The sequence of base pairs determines the genetic code. Oligogenic: caused by the influence of a few genes PCR: polymerase chain reaction: ...
Mutation
Mutation

... is degenerate, i.e. the same amino acid may have several codes. For example CAA, CAG, CAT and CAC all code for valine. In such a case any mutation is referred to as a silent mutation as it has no effect on the phenotype. However it may have a significant effect if the substitution results in a diffe ...
Translation
Translation

... mRNA is transported "om the nucleus cytoplasm where it attached with the ribosomes which are the site of protein synthesis. ...
AP Biology Review Chapters 13-14 Review Questions Chapter 12
AP Biology Review Chapters 13-14 Review Questions Chapter 12

... 11. With which organism did Beadle and Tatum experiment? What was their conclusion and the reasoning behind it? 12. What did Pauling and Itano find in their gel electrophoresis of hemoglobin? 13. Genes encode for what? (Be specific) 14. Understand the figure on pg. 241 that deals with number of nucl ...
Document
Document

... genetically identical cells produced from a single cell. • In 1997, Dolly the sheep was the first clone of an adult mammal. It took over 500 tries. ...
Slide 1
Slide 1

... copying mechanism for the genetic material.’ Their assumption would be followed up by other scientists though. ...
Which DNA sequence is most likely to form a hairpin structure? x
Which DNA sequence is most likely to form a hairpin structure? x

Chapter 8 Protein Synthesis Study Guide
Chapter 8 Protein Synthesis Study Guide

The Structure and Function of Macromolecules
The Structure and Function of Macromolecules

... due to bonding between R groups • Weak bonds: –H bonding between polar side chains –ionic bonding between charged side chains –hydrophobic and van der Waals interactions ...
Protein Interactions in an Organism Compose the Interactome
Protein Interactions in an Organism Compose the Interactome

... Molecular Basis for Relationship between Genotype and Phenotype ...
Biotechnology Applications
Biotechnology Applications

... recombinant DNA containing gene a normal allele from donor – Used to infect in vitro bone marrow cells (stem cells) from individual with genetic defect – Cells are then reintroduced into patient – Begin to produce normal proteins to combat the disease ...
Organic Molecules Power Point
Organic Molecules Power Point

... 1. Each unique: Used for Only 1 type Rx 2. Are reusable 3. Aren’t consumed in Rx 4. Can run Rx in reverse ...
The evolution of life science methodologies: From single gene
The evolution of life science methodologies: From single gene

... emulsion. One of the PCR primers is tethered to the surface (5'‐attached) of micron‐scale beads that are also included in the reaction. A low  template concentration results in most bead‐containing compartments having either zero or one template molecule present. In productive  emulsion compartments ...
Organic compounds
Organic compounds

... Provide structure for tissue and organs and carry out cell metabolism. Metabolism: all the chemical reactions that occur within an organism. The basic building blocks are amino acids (a.a.) A structural building block of many organism Enzymes are proteins ...
RNA nucleotides
RNA nucleotides

... 5. tRNA will keep matching it’s anticodon with mRNA’s codon and leaving behind amino acids until it comes to one of the stop codons. (UAG, UGA, UAA) 6. Once tRNA comes to a stop codon, it will stop translating mRNA and the long chain of amino acids will break off and become a protein (polypeptide). ...
Chapter 3
Chapter 3

... • These bond types are the ones most often broken by organisms to obtain energy. • The long chains are called polysaccharides. ...
4.2 Sources of DNA
4.2 Sources of DNA

Making Proteins - Foothill Technology High School
Making Proteins - Foothill Technology High School

... Steps of DNA Transcription Making mRNA from DNA 1. Helicase unzips DNA at the gene of interest 2. RNA polymerase matches RNA nucleotide bases to DNA, using one side as a template. 3. The mRNA strand is created. It now compliments the original DNA strand (G-C and A-U). 4. Ligase helps the strand of ...
Hoku`s Slides
Hoku`s Slides

... Several coupled DNA and protein libraries are constructed, randomizing 3 base pairs and 5 contacting amino acids for each NNNGGAGGTTTCTCTGTAAA TGANNNGGTTTCTCTGTAAA ...
< 1 ... 852 853 854 855 856 857 858 859 860 ... 1036 >

Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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