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DNA`s Discovery and Structure
DNA`s Discovery and Structure

... The DNA has a triplet code using only the 4 nucleotides, A,C,G and T. Only 3 nucleotides form a triplet which, when in a gene, codes for a part of a protein. There are 34 total different triplets that can be created but only 20 different amino acids. (Would a doublet code work just as well?? i.e. on ...
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Chapter 11: DNA and Genes
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... • Some codons do not code for amino acids; they provide instructions for making the protein. • More than one codon can code for the same amino acid. • However, for any one codon, there can be only one amino acid. • All organisms use the same genetic code. • This provides evidence that all life on E ...
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... Nucleotides are the building blocks of nucleic acids. There are two main types of nucleic acids, DNA and RNA. RNA is a single twisted strand of nucleotides, but DNA is a double twisted strand of nucleotides. Each nucleotide is made of three parts: These three parts are a phosphoric acid group, 5 thy ...
Protein Synthesis Simulation Activity
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... read (AUG codon) For each codon on the mRNA strand, the corresponding tRNA with the anticodon pairs up with the mRNA sequence The tRNA molecules carry the amino acids which are then bound together with a peptide bond to form the protein When the stop codon is reached, the protein is complete and it ...
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... 1. DNA is a polymer made of amino acids which is located in the nucleus. Each DNA nucleotide contains ribose, phosphate group, and nitrogenous bases. During DNA replication one strand of DNA acts as a template for mRNA replication. The nucleotide sequences can be divided into 3-base sequences called ...
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Lecture #7 Date

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Lab Title
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Chemistry of Life

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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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