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Dr. D. Y. Patil Biotechnology And Bioinformatics Institute, Pune
Dr. D. Y. Patil Biotechnology And Bioinformatics Institute, Pune

... Protein:The peptide Unit is rigid and planar: Peptide unit is a rigid planar arrays of four atoms (N,C,H and O), Polypeptide chains can fold into regular structures such as α-helix: Model of right handed α-helix along with dimentions, stabilization of α-helix, β -pleated sheets are stabilized by hyd ...
Principios de Biología Molecular
Principios de Biología Molecular

... • Transcription is highly regulated. Most DNA is in a dense form where it cannot be transcribed. • To begin transcription requires a promoter, a small specific sequence of DNA to which polymerase can bind (~40 base pairs “upstream” of gene) • Finding these promoter regions is a partially solved prob ...
No Slide Title
No Slide Title

... sequence by adding/eliminating a restriction site ...
Probing Essential Nucleobase Functional Groups in Aptamers and
Probing Essential Nucleobase Functional Groups in Aptamers and

... catalyzes the formation of 20 ,50 -branched RNA by forming a phosphodiester bond between the 20 OH group of an internal adenosine in one substrate and the 50 -end of a second RNA substrate (Figure 3a). The RNA substrates are bound via W.C. base-pairing and form a 3-helix-junction (3HJ) architecture ...
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Document

... protein activity ...
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... Quiz#1 LC710 ...
Chapter 2 - (www.ramsey.k12.nj.us).
Chapter 2 - (www.ramsey.k12.nj.us).

... Represent this process by redrawing the amino acids bonded together and drawing the bi-product formed. ...
Slides - Department of Computer Science • NJIT
Slides - Department of Computer Science • NJIT

... consisting of four letters: A, C, G, and T. They could be very long, e.g. thousands and even millions of letters • Proteins are also represented as strings of 20 letters (each letter is an amino acid). Their 3-D structure determines the function to a large extent. ...
051607
051607

... • Carbohydrates (sugars) – Polyhydroxy + ketone OR aldehyde – Named –ose – Typically a ring structure • -OH attack on carbonyl carbon creates a hemiacetal or hemiketal • Makes an anomeric carbon: new stereocenter – Capable of mutarotation ...
Xeroderma Pigmentosum(XP)
Xeroderma Pigmentosum(XP)

... • As a result ,person with XP are extremely sensitive to sunlight • Even very limited exposure to the direct rays of the sun can produce large numbers of dark-pigmented spots on exposed areas of the body and a greatly elevated risk of developing disfiguring and fatal skin cancers. ...
Genetic Technology
Genetic Technology

... strand of a DNA molecule at a specific nucleotides site. • When making Recombinant DNA the enzyme separates the DNA at the right spot so it can be connected to the foreign DNA ...
chapter_13_powerpointDNA_l
chapter_13_powerpointDNA_l

... DNA contains: Two Nucleotides with purine bases - Adenine (A) ...
Genomes 1
Genomes 1

Assignment 5 (Perl Project 2)
Assignment 5 (Perl Project 2)

... and t in any order. For example, acgtacccggttt is a small DNA strand. The four letters stand for the four nucleotides : adenine, cytosine, guanine, and thymine. Nucleotides, which are the molecular units from which DNA and RNA are composed, are also called bases. A special enzyme called RNA polymera ...
BCH 201 B
BCH 201 B

... Saccharide (means `Sugar’ in Greek) ...
Slide 1 - SCHOOLinSITES
Slide 1 - SCHOOLinSITES

... 5-carbon sugar ribose Contains 4 bases: C, G, A, U (uracil) Double stranded Single stranded ...
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File

... 2. Introns – transcribed into RNA and then it is spliced out or removed from protein base Initial RNA (hnRNA) is the same size as original DNA. In the cell the mRNA is shorter than hnRNA because the introns have been removed ...
Human Genome Project, Stem Cells and Cloning
Human Genome Project, Stem Cells and Cloning

... that are accessible to the public 4. Analyzing and addressing ethical, legal, & social issues involved in ...
1495/Chapter 08
1495/Chapter 08

... including projects such as the sequencing of the human genome, is often referred to as “genomics.” Many researchers claim that genomics is not nearly as significant as “proteonomics,” the study of protein structure and function. Based on the information in this chapter, which field would you argue h ...
DNA
DNA

Lectures 1 & 2 (2010.03.05 & 2010.03.06)
Lectures 1 & 2 (2010.03.05 & 2010.03.06)

... positions to allow assembly of polypeptide chain. Composed of rRNA + Proteins • Two subunits (held together by ionic bonds and hydrophobic forces) a. Small ribosomal subunit: 1 rRNA + 33 proteins b. Large ribosomal subunit: 3 rRNA + 49 proteins ...
Computer programs for the analysis and the management of DNA
Computer programs for the analysis and the management of DNA

... Programs for typing and updating DNA, RNA or amino acid data are part of the general data management system to be described in the next section. The possibility of double entry ensures that the DNA sequences are correctly typed. Program CHECK can then be used to look for typing errors. Reading data ...
Dear Jennifer - Ms. V Biology
Dear Jennifer - Ms. V Biology

... nucleotide, nucleus, ribosome, RNA polymerase, tRNA, transcription, and translation. (Hint: You can use the answer to question 2 on page 5 for the beginning of the answer to this question.) ...
File
File

... 2. Okazaki fragments form on the: lagging strand leading strand base-pairs 5' end 3. Which of the following is required for DNA replication to occur? DNA helicase DNA ligase DNA polymerase all of these 4. A nucleotide consists of: a nitrogen base a nitrogen base and a sugar a nitrogen base, sugar, a ...
Assessment Specifications
Assessment Specifications

... Understanding of the structure of DNA, and the meaning of semi-conservative replication as part of cell division, is expected. Factors affecting the processes may include both direct and indirect availability of resources. Factors that affect enzyme activity within cells may include temperature, pH, ...
< 1 ... 711 712 713 714 715 716 717 718 719 ... 1036 >

Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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