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c - Holterman
c - Holterman

... Genetic information is encoded as a sequence of nonoverlapping base triplets, or codons ...
A. biotin
A. biotin

... A compound which decreases enzyme activity by binding to a site other than the substrate binding site A compound that decreases enzyme activity by binding to the same site as the substrate binding site Isoenzymes are ...
Slides - University of Sydney
Slides - University of Sydney

Viruses and Prokaryotes
Viruses and Prokaryotes

... 4. Animal viruses may contain either DNA or RNA a) DNA viruses synthesize new nucleic acids and proteins in a manner similar to typical synthesis b) Some RNA viruses are retroviruses that use an enzyme called reverse transcriptase to transcribe RNA into a DNA intermediate, which is then used to make ...
Genome Organization
Genome Organization

Slide 1 - Montville.net
Slide 1 - Montville.net

... Take out the copied genes in plasmid from the bacteria. Take out the copied genes from the plasmids. Put the gene in another organism’s genomic DNA Reason #2 – Use to make a protein like a hormone. Gene in the plasmid can be turned on by the bacteria or yeast cell to make a protein. Extract the prot ...
REVIEW UNIT 4 & 5: HEREDITY & MOLECULAR GENETICS SAMPLE QUESTIONS
REVIEW UNIT 4 & 5: HEREDITY & MOLECULAR GENETICS SAMPLE QUESTIONS

... added plasmid ...
Genetic_Research_Lesson4_Slides_NWABR
Genetic_Research_Lesson4_Slides_NWABR

... Science was something that I was always excited about. I have one foot in anthropology as an anthropological geneticist; therefore I’m not strictly limited to a laboratory, but can go into the field for my work reconstructing the history of human populations and their origins based on population gen ...
13 Genetics - One Cue Systems
13 Genetics - One Cue Systems

... • Helps viruses infect their host by fusing with cell-membrane • Derived from host cell or nuclear membrane which is usually virus-modified • They also have some viral proteins and glycoproteins ...
crispr - UNM Biology
crispr - UNM Biology

Cloning a Paper Plasmid
Cloning a Paper Plasmid

... These are needed to transcribe the gene properly when it is read. In addition, the HindIII & EcoR1 restriction enzyme cutting sites (sequences of bases) are marked in bold on the Jellyfish Glo gene DNA. The two restriction enzymes and their respective restriction sites are listed below. These enzyme ...
DNA
DNA

... (histones).  Together, the DNA and proteins are called chromatin. The DNA molecule wraps tightly around groups of eight histone proteins,  creating small bead­like structures called  nucleosomes.  These are held  together by the attraction between the acidic portion (DNA) and alkaline  portion (hist ...
Immunosuppressive drugs: the first 50 years and a glance forward
Immunosuppressive drugs: the first 50 years and a glance forward

... Methotrexate and its polyglutamate derivatives suppress inflammatory responses through release of adenosine; they suppress immune responses by inducing the apoptosis of activated T-lymphocytes and inhibiting the synthesis of both purines and pyrimidines. Azathioprine metabolites inhibit several enzy ...
Discussion_5_Paper_Questions
Discussion_5_Paper_Questions

... Activity 2: Questions to guide student understanding of the substance in the paper: 1. In the paper, the phenotype is an insensitivity to pain. Contemplate the “plan of attack” researchers pursued to hone in on the genetic mutations responsible for the phenotype. a. The human genome consists of bil ...
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10/16

... several different methods all involving perturbing the bacterial membrane: Tbl 6.1 •Electroporation ...
Name  __________________________________ Period _________ Ms Foglia • AP Biology Date ______________________
Name __________________________________ Period _________ Ms Foglia • AP Biology Date ______________________

... These are needed to transcribe the gene properly when it is read. In addition, the HindIII & EcoR1 restriction enzyme cutting sites (sequences of bases) are marked in bold on the Jellyfish Glo gene DNA. The two restriction enzymes and their respective restriction sites are listed below. These enzyme ...
Old First Exam with answer key
Old First Exam with answer key

... A. Which enzyme would be the best to use? SapI B. Why would you select this enzyme? You need an enzyme that is efficient at cutting supercoiled DNA. NEB page 310 chart shows that only SapI is efficient at cutting supercoiled DNA. Source: lecture topic & NEB catalog 3. (2.5 pts) You need to ligate a ...
DNA properties.
DNA properties.

... Genes with a related function are frequently clustered on the chromosome. Ex: E.coli genes responsible for synthesis of Trp are clustered and order is conserved between different bacterial species. Operon: set of genes transcribed simultaneously with the same direction of ...
2_Viral _Genetics
2_Viral _Genetics

... it is the exchange of genes between two chromosomes that is based on crossing over within regions of significant base sequence homology. It can be readily demonstrated for viruses with double stranded DNA as the genetic material and has been used to determine their genetic map. ...
Mutations - Warren County Schools
Mutations - Warren County Schools

... DNA • May occur in body cells (aren’t passed to offspring) • May occur in gametes (eggs & sperm) and be passed to offspring ...
Biological information flow
Biological information flow

... transcription to premRNA processing. Fig. 38.11 Transcription and splicing are coordinated by the carboxylterminal domain (CTD) of RNA polymerase II. Functions of the CTD include: 1. Recruiting enzymes to synthesize the 5’ cap. 2. Recruiting components of the splicing complex. 3. Recruiting an endon ...
Organic Chemistry - Blue Springs R
Organic Chemistry - Blue Springs R

... • 4 electrons available and ready to bond • Carbon also likes to bond with other Carbon • this makes carbon chains! ...
Answer Key (up to 3/21)
Answer Key (up to 3/21)

Cell Bio/Physio Lecture 6 Objectives Sunday, August 14, 2011 11:41
Cell Bio/Physio Lecture 6 Objectives Sunday, August 14, 2011 11:41

... acid sequence matches exactly the geometry of the DNA sequence, allowing for this specific binding.  Zinc finger- Consists of an alpha-helix and a beta-sheet in which 4 cystein and/or histidine residues coordinately bind a zinc ion. The nucleotide recognition signal of at least one zinc finger bind ...
Influence of the environment and probes on rapid DNA sequencing
Influence of the environment and probes on rapid DNA sequencing

... by sampling the current with the driving field off. The distributions of these currents, with this particular pore geometry, for all four bases are shown in the top section of Figure 3, assuming each current is measured instantaneously.∗∗ We can see that these distributions are unique, but overlappi ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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