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Background information on testing of the Y chromosome The
Background information on testing of the Y chromosome The

CHAPTER 4: CELLULAR METABOLISM OBJECTIVES: 1. Compare
CHAPTER 4: CELLULAR METABOLISM OBJECTIVES: 1. Compare

... to synthesize specific protein molecules (remember extreme importance of enzymes in controlling metabolic processes!). The portion of a DNA molecule that contains the genetic information for making one kind of protein is called a gene. In order to understand how DNA (confined to the nucleus) can dir ...
Download PDF
Download PDF

... Biochemistry is the study of the variety of chemical structures and chemical reactions that occur in living organisms. In order to truly understand the detailed mechanisms of these diverse reactions, one must assimilate aspects of organic chemistry, inorganic chemistry, and physical chemistry and ap ...
Different transport mechanisms Aqueous diffusion Lipid
Different transport mechanisms Aqueous diffusion Lipid

... from a region of high concentration to a region of low • Example: most chemicals diffuse out of open capillary beds into extracellular space • Passive process (driven by concentration gradient) • Type of kinetics: first order (proportional to concentration • Not a saturable process • Not a competiti ...
Minor Groove to Major Groove, an Unusual DNA Sequence
Minor Groove to Major Groove, an Unusual DNA Sequence

The Development of a Method for the Characterization Of
The Development of a Method for the Characterization Of

... human versus animal sources. Presently used methods of microbial source tracking (MST) such as antibiotic resistance, phenotype number ratios, DNA sequencing and ribotyping all have certain limitations such as cost, speed, accuracy and precision. Most of these techniques depend on the belief that ce ...
Protein Synthesis Notes
Protein Synthesis Notes

... Protein Synthesis Cartoon In groups of three or four, you will make a six-step cartoon of protein synthesis on the dry-erase board provided. All of the bold terms must be labeled on your cartoon. You may use analogies to represent the structures rather than the structure themselves. Once it is appr ...
snews - The Institute of Mathematical Sciences
snews - The Institute of Mathematical Sciences

... To test their technology, the researchers sequenced the DNA. They figured out the coded order of nucleotides. That means those files were translated perfectly into DNA and back again. The information is remarkably compact, which means that it takes up very little space. For instance, one of those Sh ...
File - Central Dogma of Molecular Biology
File - Central Dogma of Molecular Biology

... model in which the new DNA strand formed contained 1/2 of the original DNA and 1/2 newly synthesized DNA--one strand was original and one strand was new. • They couldn’t rule out a model where somehow the old DNA stayed together and the newly synthesized DNA strand was completely new. ...
Slide 1
Slide 1

... strand cleavage. They are all metalloenzymes, usually using Mg. Several hammerhead structures have been solved. This one is a minimized RNA which still retains catalytic activity; it has a 16 base “enzyme” strand and a 25 base substrate strand. In the crystal, however, the usual cleavage site at C17 ...
CHAPTER 21
CHAPTER 21

... Since 38% were adenine, a further 38% would be the complimentary base thymine. Guanine and its complimentary base cytosine would therefore make up 24% of the DNA molecule. Thus guanine would make up 12%. ...
PowerPoint 簡報
PowerPoint 簡報

... RNA splicing or introduce premature stop codons, which inactivate them. These dead genes are called pseudogenes. • These processed pseudogenes have probably been produced by the reverse transcription of the mature mRNA transcript of a gene (which will itself lack introns and promoter sequences. • Ps ...
Practice Exam1
Practice Exam1

... C. is present in fetal red blood cells. D. None of the above E. All of the above 7. The configuration of most α-carbon atoms of amino acids linked in a peptide bond is A. cis B. circular C. parallel D. trans E. perpendicular 8. If a particular reaction has a negative G, is it likely to occur? A. No ...
The Structure and Function of Macromolecules
The Structure and Function of Macromolecules

... Forming a Polypeptide To join two amino acids: Carboxyl group of one must meet the amino group of another  An enzyme will join them via a dehydration reaction  The resulting bond is called a peptide bond  Repeating the process over and over creates a polypeptide ...
Eukaryotic gene expression and control
Eukaryotic gene expression and control

... Demonstrate knowledge and understanding of the process of transcription Demonstrate knowledge and understanding of the enzymes and factors required for transcription Demonstrate knowledge and understanding of the relevance of control of gene expression and the mechanisms involved at different levels ...
Stanley Miller`s Experiment
Stanley Miller`s Experiment

Pathogen induced genome instability
Pathogen induced genome instability

... into the same virion •Transduced bacterial genes are restricted to specific genes adjacent to the prophage insertion site. •In general transduction, host genes are randomly selected and almost any host gene can be transferred. ...
Factors Affecting the Absorption Properties of Chromophore
Factors Affecting the Absorption Properties of Chromophore

... Geometric features frequently have strong effects on Λmax and e. Spectra of DNA as a double stranded DNA differs from a single stranded DNA or after hydrolysis to free nucleuotides. ...
BIOCHEMISTRY AND MOLECULAR BIOLOGY
BIOCHEMISTRY AND MOLECULAR BIOLOGY

... Molecular characteristics of amino acids; stereoisomers; classification and nomenclature Physicochemical properties of amino acids. Biologically important derivatives of amino acids: keto acids, amines and polyamines Biological functions of amino acids and their derivatives Porphyrins and ferroporph ...
Treatment of Viruses
Treatment of Viruses

... A change in a single nucleotide ...
PowerPoint Presentation - Chapter 20 DNA Technology and
PowerPoint Presentation - Chapter 20 DNA Technology and

... PCR can make billions of copies of a targeted DNA segment in a few hours.  This is faster than cloning via recombinant bacteria. ...
pIRES2-AcGFP1 Vector - Clontech Laboratories, Inc.
pIRES2-AcGFP1 Vector - Clontech Laboratories, Inc.

Evidences of Evolution
Evidences of Evolution

11.0 RECOMBINANT DNA/RNA
11.0 RECOMBINANT DNA/RNA

... 11.10 FINK COMMITTEE REPORT ..................................................................................................... 5 11.11 RISK ASSESSMENT ...................................................................................................................... 5 11.12 ADDITIONAL INFORMAT ...
c - Holterman
c - Holterman

... Genetic information is encoded as a sequence of nonoverlapping base triplets, or codons ...
< 1 ... 428 429 430 431 432 433 434 435 436 ... 1036 >

Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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