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Gene Transfer
Gene Transfer

... including the incorporation of plant DNA, could be formed. A more likely event is the generation of linear DNA fragments by enzymatic cleavage or by chemical or physical breaking of the phosphodiester bonds in the plant chromosome resulting in a random assortment of fragments representative of the w ...
Nucleic Acid AptamerssFrom Selection in Vitro to Applications in Vivo
Nucleic Acid AptamerssFrom Selection in Vitro to Applications in Vivo

... G-quartet scaffold protecting them from exonuclease degradation. Small protein-binding RNA aptamers, however, usually do not contain stabilizing structural scaffolds of this kind. Therefore, for them to be widely applicable as potential therapeutics, diagnostics, or assay components, the capacity of ...
Advanced Plant Technology Program Vocabulary
Advanced Plant Technology Program Vocabulary

... Marker assisted breeding or selection (MAB or MAS) (noun): Process by which certain specimens are selected based on the presence or absence of a genetic marker in their DNA. MAS is used often in plant breeding programs to select plants that have genes for traits of interest. N Nucleotide (noun): The ...
Slide 1
Slide 1

... • Plants that have had drugs applied to them to prevent the nondisjunction of chromosomes during meiosis are called this. • Answer • What are polyploid plants? ...
Press Release
Press Release

... decay started after translation was complete and that decaying RNA molecules provided little biological information. Now a team from EMBL Heidelberg and Stanford University led by Lars Steinmetz has turned this on its head. The researchers have shown that one end of the mRNA begins to decay while th ...
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Vocabulary

... 10. What molecules in photosynthesis/cellular respiration undergo oxidation? Reduction? 11. What are photosystems? How are they involved in electron transport systems in ...
La génétique - Ms McRae`s Science
La génétique - Ms McRae`s Science

... contains instructions for synthesizing a protein called huntingtin, whose exact function in our neurons remains unexplained. It is known, however, that a particular amino acid is repeated in its structure. If this amino acid is repeated fewer than 35 times in a row, the carrier does not normally suf ...
Mutational Analysis Defines the Roles of Conserved Amino Acid
Mutational Analysis Defines the Roles of Conserved Amino Acid

... which suggests that this amino acid is important (albeit not essential) for catalysis. The opposite side of the predicted adeninebinding site comprises amino acid residues from the conserved motif VIII (Figures 1 and 2). We have analyzed four residues from this motif, F163, P165, K166 and K168. P165 ...
macromolecules
macromolecules

... 5.4 Proteins have many structures, resulting in a wide range of functions • Proteins account for more than 50% of the dry weight of most cells. • Humans have tens of thousands of different proteins, each with a specific structure and function. • The most important type of protein may be enzymes. • E ...
A Recipe for Traits - Learn Genetics (Utah)
A Recipe for Traits - Learn Genetics (Utah)

... • In this activity, a single gene determined each dog trait. More often a trait is influenced by more than one ...
Chapter 7  - McGraw Hill Higher Education
Chapter 7 - McGraw Hill Higher Education

... The amino acid sequence in albumin is dictated by the sequence of nucleotides in the RNA molecule. The RNA, in turn, was transcribed from DNA. In this way, DNA provides the recipe for albumin and every other protein in the cell. Clearly, RNA is central to the flow of genetic information. This multif ...
S1 Text.
S1 Text.

Molecular
Molecular

... During last week’s lab you exposed his- mutant strains of S. typhimurium to suspected mutagens. Some of your his- bacteria reverted to a his+ phenotype, but how do you suppose this happened? As you remember, different mutagens affect DNA in different ways. However, even though a specific mutagen wil ...
Dr. Assal - World Health Organization
Dr. Assal - World Health Organization

... • Standardization of the different steps, from sample preparation to amplification and ...
Serine - Spectracell
Serine - Spectracell

... Function: Serine is used to manufacture proteins, energy, cell membrane structure and synthesis of other cell components (DNA and RNA). Serine is a dispensable amino acid obtained from the diet and synthesized from other amino acids and metabolites of glucose. Serine participates in protein synthesi ...
Metagenomics NGS intro 2015
Metagenomics NGS intro 2015

Genes and Genetic Diseases Paula Ruedebusch
Genes and Genetic Diseases Paula Ruedebusch

...  Composed of amino acids ...
Proteins
Proteins

... • β-pleated sheets: area where 2 or more regions of the polypeptide chain lie in parallel ...
Analysis of Cell Ageing
Analysis of Cell Ageing

... Q1 - Vogelstein and his colleagues were able to determine the order of genetic changes since they had access to staged samples (staged macroscopically) of colon cancer. They were able to perform tests on these in order to deduce which genes were affected during the progression. Q2/3/4/5 - ...
Chapter 2 Assignment: Genetics
Chapter 2 Assignment: Genetics

... 18. Which scientist discovered that the DNA molecule has a helix shape? A. B. C. D. ...
The amino acids
The amino acids

... common that they have short side chains that can form hydrogen bonds with the own backbone. These hydrogen bonds compensate the energy loss caused by bending the chain into a ...
Principles of Virology
Principles of Virology

... into 3’-OH of DNA chain • DNA is always synthesized 5’-3’ via semiconservative replication (two daughter strands) • Replication initiates at specific sites on template called origins • Catalyzed by DdDp + accessory proteins • Primer-dependent ...
Quiz 9 BIol203 Fall 2013ppt
Quiz 9 BIol203 Fall 2013ppt

Metabolism: the Degradation and Synthesis of Living Cells
Metabolism: the Degradation and Synthesis of Living Cells

... phosphorylated intermediates (Nobel Prize in 1929). ...
Amines and Amides
Amines and Amides

... • Fourth most common atom in living systems. • Important component of the structure of nucleic acids, DNA, and RNA • Essential to the structure and function of proteins – enzymes and antibodies ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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