medbiochem exam 1, 2000
... 41. Competitive inhibitors are commonly used in chemotherapy because: A. the inhibitors decrease the total amount of substrate. B. the inhibitors alter the enzymes when they bind and decrease the Vmax of the reaction C. the inhibitor resembles the structure of the product and inhibit the reaction by ...
... 41. Competitive inhibitors are commonly used in chemotherapy because: A. the inhibitors decrease the total amount of substrate. B. the inhibitors alter the enzymes when they bind and decrease the Vmax of the reaction C. the inhibitor resembles the structure of the product and inhibit the reaction by ...
Introduction - MRC Laboratory of Molecular Biology
... Total extracellular pyruvate/lactate PER2::LUC ...
... Total extracellular pyruvate/lactate PER2::LUC ...
File - Mrs Jones A
... lipids have more, hydrogen / hydrogen – carbon bonds ; more acetyl coenzyme A generated / more ‘turns’ of Krebs cycle ; ...
... lipids have more, hydrogen / hydrogen – carbon bonds ; more acetyl coenzyme A generated / more ‘turns’ of Krebs cycle ; ...
檔案下載
... – Biotin-Enzyme + HOCO2-PO32- CO2-biotin-enzyme + Pi – CO2-biotin-enzyme + pyruvate biotin-enzyme + oxaloacetate ...
... – Biotin-Enzyme + HOCO2-PO32- CO2-biotin-enzyme + Pi – CO2-biotin-enzyme + pyruvate biotin-enzyme + oxaloacetate ...
Communication, Homeostasis
... No recycling of NAD so the krebs cycle, link reaction stops as they all require NAD. This means there is also no substrate level phosphorylation Therefore there is no ATP produced If only there was a way to at least recycle the NAD we could make a little ATP from substrate level phosphorylat ...
... No recycling of NAD so the krebs cycle, link reaction stops as they all require NAD. This means there is also no substrate level phosphorylation Therefore there is no ATP produced If only there was a way to at least recycle the NAD we could make a little ATP from substrate level phosphorylat ...
Respiration
... cycle, and electron transport • Respiration occurs in three metabolic stages: glycolysis, the Krebs cycle, and the electron transport chain & oxidative phosphorylation. • Glycolysis occurs in the cytoplasm. – It begins catabolism by breaking glucose into two molecules of ...
... cycle, and electron transport • Respiration occurs in three metabolic stages: glycolysis, the Krebs cycle, and the electron transport chain & oxidative phosphorylation. • Glycolysis occurs in the cytoplasm. – It begins catabolism by breaking glucose into two molecules of ...
Metabolic Engineering for Fuels and Chemicals
... (mutations in mlc, crp, csrA) Global regulators for redox control (mutations in fnr, arcA) Prolonging the growth phase and metabolism (comparing ethanol/lactic acid) ...
... (mutations in mlc, crp, csrA) Global regulators for redox control (mutations in fnr, arcA) Prolonging the growth phase and metabolism (comparing ethanol/lactic acid) ...
Regulation of Glycolysis - Valdosta State University
... • It is formed from F6P by the enzyme phosphofructokinase-2 (PFK-2) • It is broken down by the same enzyme, but at a different catalytic site in the enzyme – it’s a bifunctional protein ...
... • It is formed from F6P by the enzyme phosphofructokinase-2 (PFK-2) • It is broken down by the same enzyme, but at a different catalytic site in the enzyme – it’s a bifunctional protein ...
Citric Acid Cycle
... Electrons from these oxidation processes are then used to reduce oxygen to water with the concomitant formation of ATP. The unique structural aspects of mitochondria facilitate its energy-harvesting role. ...
... Electrons from these oxidation processes are then used to reduce oxygen to water with the concomitant formation of ATP. The unique structural aspects of mitochondria facilitate its energy-harvesting role. ...
1. Metabolic pathways 2. Basic enzyme kinetics 3. Metabolic
... » ATP binding decreases affinity for F6P (substrate) » F-2,6-P binding causes large increase in F6P affinity » Glycolytic flux stimulated by F-2,6-P & inhibited by ATP ...
... » ATP binding decreases affinity for F6P (substrate) » F-2,6-P binding causes large increase in F6P affinity » Glycolytic flux stimulated by F-2,6-P & inhibited by ATP ...
2 ATP - HONORS BIOLOGY
... Energized electrons from NADH and FADH2 enter the ETC and pump Hydrogen ions into the intermembranous space. Hydrogen ions pass through ATP Synthase to make ATP. Electrons pass from the ETC to Oxygen which then combines with Hydrogen ions to make water. The whole process is called Chemiosmotic Phosp ...
... Energized electrons from NADH and FADH2 enter the ETC and pump Hydrogen ions into the intermembranous space. Hydrogen ions pass through ATP Synthase to make ATP. Electrons pass from the ETC to Oxygen which then combines with Hydrogen ions to make water. The whole process is called Chemiosmotic Phosp ...
NAD - wwphs
... Enzymes (Cytochromes) and ATP synthase on membrane to shuttle electrons and protons NADH, FADH2 gives up the H H+ + e Electrons are passed through the membrane proteins and the energy released is used to transport the H to the outer membrane The gradient established is the force needed to allow the ...
... Enzymes (Cytochromes) and ATP synthase on membrane to shuttle electrons and protons NADH, FADH2 gives up the H H+ + e Electrons are passed through the membrane proteins and the energy released is used to transport the H to the outer membrane The gradient established is the force needed to allow the ...
THE CITRIC ACID CYCLE
... and more ATP can be made by oxidative phosphorylation. The oxidation of pyruvate: is catalysed by pyruvate dehydrogenase; is complex; is essentially irreversible under intracellular conditions; occurs in mitochondria in eukaryotic cells. ...
... and more ATP can be made by oxidative phosphorylation. The oxidation of pyruvate: is catalysed by pyruvate dehydrogenase; is complex; is essentially irreversible under intracellular conditions; occurs in mitochondria in eukaryotic cells. ...
Triosephosphate Isomerase (T6258) - Datasheet - Sigma
... Triosephosphate Isomerase from rabbit muscle Catalog Number T6258 Storage Temperature –20 °C CAS RN 9023-78-3 EC 5.3.1.1 Synonyms: TPI; D-Glyceraldehyde-3-phosphate ketolisomerase Product Description Triosephosphate Isomerase (TPI) catalyzes the interconversion of D-glyceraldehyde 3-phosphate (GAP) ...
... Triosephosphate Isomerase from rabbit muscle Catalog Number T6258 Storage Temperature –20 °C CAS RN 9023-78-3 EC 5.3.1.1 Synonyms: TPI; D-Glyceraldehyde-3-phosphate ketolisomerase Product Description Triosephosphate Isomerase (TPI) catalyzes the interconversion of D-glyceraldehyde 3-phosphate (GAP) ...
Biochemistry 304 2014 Student Edition Gluconeogenesis Lectures
... Different organs/tissues in the body can be metabolically linked. Lactate produced by active skeletal muscle and erythrocytes is an energy source for other organs. •Skeletal muscle during vigorous exercise produces pyruvate at a rate faster than oxidative metabolism via the citric acid cycle can use ...
... Different organs/tissues in the body can be metabolically linked. Lactate produced by active skeletal muscle and erythrocytes is an energy source for other organs. •Skeletal muscle during vigorous exercise produces pyruvate at a rate faster than oxidative metabolism via the citric acid cycle can use ...
carbohydrate metabolism
... G-6-PD catalyzes formation of NADPH + H in HMP shunt Hemolytic anemia usually occur in individuals with G-6-PD deficiency HMP shunt will not produce enough NADPH required to maintain high level of GSH to protect RBC from Oxidative damage Hemolysis of RBC will occur because Oxidants will accu ...
... G-6-PD catalyzes formation of NADPH + H in HMP shunt Hemolytic anemia usually occur in individuals with G-6-PD deficiency HMP shunt will not produce enough NADPH required to maintain high level of GSH to protect RBC from Oxidative damage Hemolysis of RBC will occur because Oxidants will accu ...
Lecture Seventeen - Personal Webspace for QMUL
... These are at the two positions where ATP is formed 1: The 1,3-Bisphosphoglycerate to 3-Phosphoglycerate The 1,3-BPG passes a phosphate to ADP This is known as substrate-level phosphorylation ...
... These are at the two positions where ATP is formed 1: The 1,3-Bisphosphoglycerate to 3-Phosphoglycerate The 1,3-BPG passes a phosphate to ADP This is known as substrate-level phosphorylation ...
pH Dependence of Blood-Brain Barrier Permeability to
... transport also involve changes in ionizable groups on the transport carrier. Such an explanation could not, however, be invoked in the case of membrane penetration of compounds such as nicotine which gain access to the brain by virtue of their lipid solubility. In the early post-ischemic brain there ...
... transport also involve changes in ionizable groups on the transport carrier. Such an explanation could not, however, be invoked in the case of membrane penetration of compounds such as nicotine which gain access to the brain by virtue of their lipid solubility. In the early post-ischemic brain there ...
All 3 fates of pyruvate from glycolysis provide for the regeneration of
... stimulates conversion of glucose to fats, proteins, ribulose 5-phosphate and glycogen; inhibits the conversion of fats, proteins, glycogen and ribulose 5-phosphate to glucose ...
... stimulates conversion of glucose to fats, proteins, ribulose 5-phosphate and glycogen; inhibits the conversion of fats, proteins, glycogen and ribulose 5-phosphate to glucose ...
Integration of Metabolism: Glucose Synthesis
... In the liver, lactate is oxidized to pyruvate by lactate dehydrogenase. This pyruvate undergoes gluconeogenesis to produce free glucose, which is released into the blood. The liver restores the level of glucose necessary for active muscle cells to continue anaerobic glycolysis for immediate energy n ...
... In the liver, lactate is oxidized to pyruvate by lactate dehydrogenase. This pyruvate undergoes gluconeogenesis to produce free glucose, which is released into the blood. The liver restores the level of glucose necessary for active muscle cells to continue anaerobic glycolysis for immediate energy n ...
Bioenergetics and Metabolism
... 4. What are examples of glycolysis in real life? Glycolysis is the sole source of ATP under anaerobic conditions which can occur in animal muscle tissue during intense exercise. Fermentation also relies on glycolysis which is a process that is used to make alcoholic beverages when yeast cells are pr ...
... 4. What are examples of glycolysis in real life? Glycolysis is the sole source of ATP under anaerobic conditions which can occur in animal muscle tissue during intense exercise. Fermentation also relies on glycolysis which is a process that is used to make alcoholic beverages when yeast cells are pr ...
Cellular Respiration Part 3
... ▫ Carbon atom is removed (3C to 2C) and released as CO2 ▫ 2C compound is oxidized while NAD+ is reduced to NADH ▫ Coenzyme A joins with 2C to form acetyl co-A ...
... ▫ Carbon atom is removed (3C to 2C) and released as CO2 ▫ 2C compound is oxidized while NAD+ is reduced to NADH ▫ Coenzyme A joins with 2C to form acetyl co-A ...
CH 2
... pentose phosphate pathway are used for quite different purposes, it is sometimes necessary to produce them in different amounts. Therefore, the cell has different modes in which the pentose phosphate pathway can function. In the case where much more ribose-5-phosphate is required than NADPH, the rib ...
... pentose phosphate pathway are used for quite different purposes, it is sometimes necessary to produce them in different amounts. Therefore, the cell has different modes in which the pentose phosphate pathway can function. In the case where much more ribose-5-phosphate is required than NADPH, the rib ...
Lactate dehydrogenase
A lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells (animals, plants, and prokaryotes). LDH catalyzes the conversion of pyruvate to lactate and back, as it converts NADH to NAD+ and back. A dehydrogenase is an enzyme that transfers a hydride from one molecule to another.LDH exist in four distinct enzyme classes. This article is about the common NAD(P)-dependent L-lactate dehydrogenase. Other LDHs act on D-lactate and/or are dependent on cytochrome c: D-lactate dehydrogenase (cytochrome)) and L-lactate (L-lactate dehydrogenase (cytochrome)). LDH has been of medical significance because it is found extensively in body tissues, such as blood cells and heart muscle. Because it is released during tissue damage, it is a marker of common injuries and disease such as heart failure.