Distribution of GABAergic neurons and axon terminals in the
... Neurons that utilize the neurotransmitter y-aminobutyric acid (GABA) appear to play an important role in generating many of the receptive field properties that distinguish neurons in the striate cortex from those in the lateral geniculate nucleus. When the inhibitory effects of GABA are blocked by t ...
... Neurons that utilize the neurotransmitter y-aminobutyric acid (GABA) appear to play an important role in generating many of the receptive field properties that distinguish neurons in the striate cortex from those in the lateral geniculate nucleus. When the inhibitory effects of GABA are blocked by t ...
Graziano's CV
... Graziano MSA (2014) How Ventriloquism Works. Frontiers for young minds, DOI:10.3389/frym.2014.00004. Graziano MSA and Kastner S (2011) Human consciousness and its relationship to social neuroscience: A novel hypothesis. Cognitive Neuroscience, 2: 98-113. Graziano MSA and Kastner S (2011) Awareness a ...
... Graziano MSA (2014) How Ventriloquism Works. Frontiers for young minds, DOI:10.3389/frym.2014.00004. Graziano MSA and Kastner S (2011) Human consciousness and its relationship to social neuroscience: A novel hypothesis. Cognitive Neuroscience, 2: 98-113. Graziano MSA and Kastner S (2011) Awareness a ...
Dorsal Anterior Cingulate Cortex: A Bottom-Up View
... projections to and from the major brain systems that are associated with emotion [amygdala, hypothalamus, ventromedial prefrontal cortex (vmPFC), insula, ventral striatum], cognition and executive control (dorsal prefrontal cortex, ventrolateral prefrontal cortex, frontal pole, parietal cortex), and ...
... projections to and from the major brain systems that are associated with emotion [amygdala, hypothalamus, ventromedial prefrontal cortex (vmPFC), insula, ventral striatum], cognition and executive control (dorsal prefrontal cortex, ventrolateral prefrontal cortex, frontal pole, parietal cortex), and ...
Limbic systems for emotion and for memory, but no
... cingulate cortex for actioneoutcome learning. In this ‘emotion limbic system’ a computational principle is that feedforward pattern association networks learn associations ...
... cingulate cortex for actioneoutcome learning. In this ‘emotion limbic system’ a computational principle is that feedforward pattern association networks learn associations ...
Magnocellular and Parvocellular Contributions to
... subdivisions of the primate dorsal LGN remain largely segregated through several levels of cortical processing. It has been suggested that this segregation persists through to the highest stages of the visual cortex, and that the pronounced differences beween the neuronal response properties in the ...
... subdivisions of the primate dorsal LGN remain largely segregated through several levels of cortical processing. It has been suggested that this segregation persists through to the highest stages of the visual cortex, and that the pronounced differences beween the neuronal response properties in the ...
The dorsal raphe nucleus—From silver stainings to a role in
... Cajal observed that the DRN contained four types of neurons, which he described as being voluminous, fusiform, triangular and stellate. His description is in accordance with modern reports on other mammals, which also identify four morphologically distinct types of neurons in the DRN. They have been ...
... Cajal observed that the DRN contained four types of neurons, which he described as being voluminous, fusiform, triangular and stellate. His description is in accordance with modern reports on other mammals, which also identify four morphologically distinct types of neurons in the DRN. They have been ...
ABSTRACT The Auditory Brainstem Response: History and Future
... The point at which the axon of one neuron connects to another neuron is called a synapse. The axon terminal contains vesicles, bubbles formed by a phospholipid membrane, filled with signaling molecules called neurotransmitters. When an action potential reaches the axon terminal, the membrane depolar ...
... The point at which the axon of one neuron connects to another neuron is called a synapse. The axon terminal contains vesicles, bubbles formed by a phospholipid membrane, filled with signaling molecules called neurotransmitters. When an action potential reaches the axon terminal, the membrane depolar ...
Plastic Effect of Tetanic Stimulation on Auditory Evoked Potentials
... changes in the central nervous system in response to altered patterns of stimulation. In sensory and motor systems, demands for transmitting sensory or motor information within these systems can change when there (1) are altered patterns of stimulation (peripheral or central) and/or (2) is a loss of ...
... changes in the central nervous system in response to altered patterns of stimulation. In sensory and motor systems, demands for transmitting sensory or motor information within these systems can change when there (1) are altered patterns of stimulation (peripheral or central) and/or (2) is a loss of ...
Do superior colliculus projection zones in the inferior pulvinar
... Twelve to 24 h after perfusion, the cortex and brainstem (including the thalamus) were cut into 40–50-µm sections on a freezing microtome. A block of flattened cortex containing the MT and other visual areas was cut parallel to the surface, and divided into three series of sections. One series was m ...
... Twelve to 24 h after perfusion, the cortex and brainstem (including the thalamus) were cut into 40–50-µm sections on a freezing microtome. A block of flattened cortex containing the MT and other visual areas was cut parallel to the surface, and divided into three series of sections. One series was m ...
Glucose-sensing neurons: Are they physiologically relevant?
... homeostasis and energy balance. However, little is known about how the brain actually senses and responds to changes in extracellular glucose. While there are neurons in the brain that change their action potential frequency in response to changes in extracellular glucose, most studies of these neur ...
... homeostasis and energy balance. However, little is known about how the brain actually senses and responds to changes in extracellular glucose. While there are neurons in the brain that change their action potential frequency in response to changes in extracellular glucose, most studies of these neur ...
Limbic structures, emotion, and memory
... that the computations in the two systems are very different (Rolls, 2015b). In doing this, I also provide an introduction to Emotion and Memory, which are included in this section of the Reference Module in Neuroscience and Biobehavioral Psychology. ...
... that the computations in the two systems are very different (Rolls, 2015b). In doing this, I also provide an introduction to Emotion and Memory, which are included in this section of the Reference Module in Neuroscience and Biobehavioral Psychology. ...
Projections of the paraventricular and paratenial nuclei
... and no previous study has comprehensively analyzed PT projections. By using the anterograde anatomical tracer, Phaseolus vulgaris leucoagglutinin, and the retrograde tracer, FluoroGold, we examined the efferent projections of PV and PT. We showed that the output of PV is virtually directed to a disc ...
... and no previous study has comprehensively analyzed PT projections. By using the anterograde anatomical tracer, Phaseolus vulgaris leucoagglutinin, and the retrograde tracer, FluoroGold, we examined the efferent projections of PV and PT. We showed that the output of PV is virtually directed to a disc ...
thyroid hormones in brain development and
... circulation, and in part is formed locally by 5’-deiodination of T4, mediated by Dio2 in the astrocytes, in proportions that depend on the developmental stage. T4 and T3 are degraded by Dio3 present in neurons. Entry of T4 and T3 in brain is facilitated by specific transmembrane transporters, mainly ...
... circulation, and in part is formed locally by 5’-deiodination of T4, mediated by Dio2 in the astrocytes, in proportions that depend on the developmental stage. T4 and T3 are degraded by Dio3 present in neurons. Entry of T4 and T3 in brain is facilitated by specific transmembrane transporters, mainly ...
Rules Ventral Prefrontal Cortical Axons Use to Reach Their Targets
... differences in the trajectories of fibers from different vPFC areas. Overall, the medial/lateral vPFC position dictates the route that fibers take to enter major WM tracts, as well as the position within specific tracts: axons from medial vPFC regions travel ventral to those from more lateral areas. ...
... differences in the trajectories of fibers from different vPFC areas. Overall, the medial/lateral vPFC position dictates the route that fibers take to enter major WM tracts, as well as the position within specific tracts: axons from medial vPFC regions travel ventral to those from more lateral areas. ...
Supplementary Motor Area and Presupplementary Motor Area
... differential origin of subcortical projections to the SMA and pre-SMA suggests that these cortical areas are nodes in distinct neural systems. Although both systems are the target of outputs from the basal ganglia and the cerebellum, these two cortical areas seem to be dominated by basal ganglia inp ...
... differential origin of subcortical projections to the SMA and pre-SMA suggests that these cortical areas are nodes in distinct neural systems. Although both systems are the target of outputs from the basal ganglia and the cerebellum, these two cortical areas seem to be dominated by basal ganglia inp ...
Generation of Theta and Gamma Rhythms in the Hippocampus
... LEUNG, L. S. Generation of theta and gamma rhythms in the hippocampus. NEUROSCI BIOBEHAV REV 22(2), 275–290, 1998.—In the behaving rat, theta rhythm was dominant during walking and rapid-eye-movement sleep, while irregular slow activity predominated during immobility and slow-wave sleep. Oscillatory ...
... LEUNG, L. S. Generation of theta and gamma rhythms in the hippocampus. NEUROSCI BIOBEHAV REV 22(2), 275–290, 1998.—In the behaving rat, theta rhythm was dominant during walking and rapid-eye-movement sleep, while irregular slow activity predominated during immobility and slow-wave sleep. Oscillatory ...
Neural systems for guilt from actions affecting self versus others
... diminished guilt and compassion (Koenigs et al., 2007). Investigation of the evaluative processes comparing guilt and embarrassment showed that both conditions commonly activated the medial PFC and the left superior temporal sulcus (STS) (Takahashi et al., 2004). In parallel to these studies of emot ...
... diminished guilt and compassion (Koenigs et al., 2007). Investigation of the evaluative processes comparing guilt and embarrassment showed that both conditions commonly activated the medial PFC and the left superior temporal sulcus (STS) (Takahashi et al., 2004). In parallel to these studies of emot ...
Retinotopic Organization and Functional Subdivisions of the Human
... Functional magnetic resonance imaging (fMRI) has provided intriguing insights into the topography and functional organization of visual cortical areas in the human brain. However, little is known about the functional anatomy of subcortical nuclei. Here, we used high-resolution fMRI (1.5 ⫻ 1.5 ⫻ 2 mm ...
... Functional magnetic resonance imaging (fMRI) has provided intriguing insights into the topography and functional organization of visual cortical areas in the human brain. However, little is known about the functional anatomy of subcortical nuclei. Here, we used high-resolution fMRI (1.5 ⫻ 1.5 ⫻ 2 mm ...
Review International Journal of Integrative Biology Reticular
... reticular brainstem core is characterized foremost by loosely arranged small and medium-sized neurons. The main exception occurs in the central parts of the upper medulla and lower pons, where a significant number of large cells intermingle with small and medium sized cells. This region is referred ...
... reticular brainstem core is characterized foremost by loosely arranged small and medium-sized neurons. The main exception occurs in the central parts of the upper medulla and lower pons, where a significant number of large cells intermingle with small and medium sized cells. This region is referred ...
Dynamics and Synchronization of Motifs of Neuronal Populations in the Presence
... The purpose of this introductory chapter is twofold: to motivate, and to contextualize. The motivation aims at evidencing the importance of synchronization to brain functioning. Consciousness, cognition, behavior and perception require the interaction of multiple large groups of interconnected neuro ...
... The purpose of this introductory chapter is twofold: to motivate, and to contextualize. The motivation aims at evidencing the importance of synchronization to brain functioning. Consciousness, cognition, behavior and perception require the interaction of multiple large groups of interconnected neuro ...
Human brain
The human brain is the main organ of the human nervous system. It is located in the head, protected by the skull. It has the same general structure as the brains of other mammals, but with a more developed cerebral cortex. Large animals such as whales and elephants have larger brains in absolute terms, but when measured using a measure of relative brain size, which compensates for body size, the quotient for the human brain is almost twice as large as that of a bottlenose dolphin, and three times as large as that of a chimpanzee. Much of the size of the human brain comes from the cerebral cortex, especially the frontal lobes, which are associated with executive functions such as self-control, planning, reasoning, and abstract thought. The area of the cerebral cortex devoted to vision, the visual cortex, is also greatly enlarged in humans compared to other animals.The human cerebral cortex is a thick layer of neural tissue that covers most of the brain. This layer is folded in a way that increases the amount of surface that can fit into the volume available. The pattern of folds is similar across individuals, although there are many small variations. The cortex is divided into four lobes – the frontal lobe, parietal lobe, temporal lobe, and occipital lobe. (Some classification systems also include a limbic lobe and treat the insular cortex as a lobe.) Within each lobe are numerous cortical areas, each associated with a particular function, including vision, motor control, and language. The left and right sides of the cortex are broadly similar in shape, and most cortical areas are replicated on both sides. Some areas, though, show strong lateralization, particularly areas that are involved in language. In most people, the left hemisphere is dominant for language, with the right hemisphere playing only a minor role. There are other functions, such as visual-spatial ability, for which the right hemisphere is usually dominant.Despite being protected by the thick bones of the skull, suspended in cerebrospinal fluid, and isolated from the bloodstream by the blood–brain barrier, the human brain is susceptible to damage and disease. The most common forms of physical damage are closed head injuries such as a blow to the head, a stroke, or poisoning by a variety of chemicals which can act as neurotoxins, such as ethanol alcohol. Infection of the brain, though serious, is rare because of the biological barriers which protect it. The human brain is also susceptible to degenerative disorders, such as Parkinson's disease, and Alzheimer's disease, (mostly as the result of aging) and multiple sclerosis. A number of psychiatric conditions, such as schizophrenia and clinical depression, are thought to be associated with brain dysfunctions, although the nature of these is not well understood. The brain can also be the site of brain tumors and these can be benign or malignant.There are some techniques for studying the brain that are used in other animals that are just not suitable for use in humans and vice versa. It is easier to obtain individual brain cells taken from other animals, for study. It is also possible to use invasive techniques in other animals such as inserting electrodes into the brain or disabling certains parts of the brain in order to examine the effects on behaviour – techniques that are not possible to be used in humans. However, only humans can respond to complex verbal instructions or be of use in the study of important brain functions such as language and other complex cognitive tasks, but studies from humans and from other animals, can be of mutual help. Medical imaging technologies such as functional neuroimaging and EEG recordings are important techniques in studying the brain. The complete functional understanding of the human brain is an ongoing challenge for neuroscience.