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Motor learning in man: A review of functional and clinical studies
Motor learning in man: A review of functional and clinical studies

... (iii) subjects reached a plateau level of performance, the slope was constant. The results are in agreement with the findings by Sailer et al. (2005) who reported similar learning stages for a task in which subjects had to coordinate bi manual motor actions. Looking at the neural mechanisms underlyin ...
Document
Document

... property called LTP (long term potentiation). This short term memory is neuron functional state that activates signaling genes, e.g. c-fos. These early genes trigger phenotypic genes related to protein production during the second state. • The second state occurs during sleep as the memory-consolida ...
Hypothesized Deficiency of Guanine
Hypothesized Deficiency of Guanine

... CSF. In view of this, lowered CSF HVA levels in Lesch-Nyhan syndrome implicate the basal ganglia in the emergence of at least some of the CNS symptoms (eg, choreoathetosis). Perhaps a diminished release of dopamine from terminals within basal ganglia leads to a compensatory up-regulation in the sens ...
An optical neural interface: in vivo control of
An optical neural interface: in vivo control of

... For example, in neuroscience, genetically targeted and temporally precise manipulation of neuronal activity would enable exploration of the causal function of individual neuron types in intact circuits. In the clinical setting, precise control over specific molecularly distinct cell types within int ...
The Effect of Movement Rate and Complexity on
The Effect of Movement Rate and Complexity on

... Many studies have used functional imaging technologies such as positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) to examine the effects of movement rate and complexity on human brain activity (Blinkenberg et al., 1996; Jancke et al., 1998; Jancke, Specht, Mirzazade, ...
SCIENCE 101: Cranial Nerve I: The Olfactory Nerve
SCIENCE 101: Cranial Nerve I: The Olfactory Nerve

... BLOW YOUR MIND!?). The mitral cells have their dendrites arranged into large trees called glomeruli which get a TON of information, you can get thousands of olfactory receptor neurons (all of which express the same kind of receptor protein) synapsing onto only one or two glomeruli (though the glomer ...
Developmental Changes Revealed by Immunohistochemical
Developmental Changes Revealed by Immunohistochemical

... cells undergoing cell division; the intermediate zone (IZ), which can be further subdivided into the radiations (RA) and the subplate (SP); the cell-dense cortical plate (CP), which contains the accumulating postmigratory neurons of the adult cerebral cortex; and the marginal zone (MZ) (Boulder Comm ...
The Brain and Nervous Systems
The Brain and Nervous Systems

... Are There “His” and “Hers” Brains? (2 of 3) • Some of the brain research has focused on behavioral or cognitive differences that are small and insignificant. – Even when gender differences are statistically significant, they are often quite small in practical terms. ...
When the Sun Prickles Your Nose: An EEG Study Identifying
When the Sun Prickles Your Nose: An EEG Study Identifying

... Background: Exposure to bright light such as sunlight elicits a sneeze or prickling sensation in about one of every four individuals. This study presents the first scientific examination of this phenomenon, called ‘the photic sneeze reflex’. Methodology and Principal Findings: In the present experim ...
Lecture Guide - TestbankCart.com
Lecture Guide - TestbankCart.com

... 2. The cortex is the outer covering of the cerebrum and consists of a tightly packed layer of neurons about one tenth of an inch in thickness. Its wrinkles, or corticalization, allow for greater cortical area and are associated with greater brain complexity. 3. The cortex is divided into two cerebra ...
Ch. 49
Ch. 49

... suprachiasmatic nuclei (SCN) in the hypothalamus that function as a biological clock • Biological clocks usually require external cues to remain synchronized with environmental cycles Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
Selkoe (Nat Cell Biol
Selkoe (Nat Cell Biol

... all of which have so far been shown to be single-spanning transmembrane proteins that must first undergo α-secretase-mediated shedding of their ectodomains before presenilin−γ-secretase can cleave within the membrane37. It could be reasoned that presenilin missense mutations cause Alzheimer’s diseas ...
here - Aerotoxic Association
here - Aerotoxic Association

5. the architecture of the visual cortex
5. the architecture of the visual cortex

... is folded under in a complicated way, but these two parts are actually continuous. The lightly stained substance is white matter; it lies under the part of the cortex that is exposed to the surface, separating it from the buried fold of cortex, and consists mainly of myelinated nerve fibers, which d ...
Role of the thalamic nucleus reuniens in mediating interactions
Role of the thalamic nucleus reuniens in mediating interactions

... Nonetheless, the mPFC is certainly involved in working memory, among other complex cognitive functions. Evidence from in vivo electrophysiology studies shows that single mPFC neurons exhibit a variety of behavioral correlates during navigation and working memory tasks. Because the mPFC is the recipi ...
Role of the thalamic nucleus reuniens in mediating interactions
Role of the thalamic nucleus reuniens in mediating interactions

... Nonetheless, the mPFC is certainly involved in working memory, among other complex cognitive functions. Evidence from in vivo electrophysiology studies shows that single mPFC neurons exhibit a variety of behavioral correlates during navigation and working memory tasks. Because the mPFC is the recipi ...
8 geriatric otolaryngology - RASP!
8 geriatric otolaryngology - RASP!

... A comprehensive literature search was conducted on the National Library of Medicine’s PubMed database. The initial review by Staecker covered the time period from 1980 to April 2001. 1 This follow-up review adds publications from April 2001 through October 2005. The search strategy combined various ...
The caudal part of the frontal cortex is strongly involved - LIRA-Lab
The caudal part of the frontal cortex is strongly involved - LIRA-Lab

... demonstrate that premotor neurons of area F5 (the ventral premotor cortex where mirror neurons have been located) apparently devoid of any visual property, indeed respond to the vision of one’s own acting hand. This hypothesis, which has been largely confirmed by the experiments presented here, may ...
I study the neural circuits that move bodies
I study the neural circuits that move bodies

... I feel lucky to be part of the first group of thesis students to have come through Erik's lab. I think that electrophysiology is some of the coolest, most hands-on biology around, and it was gratifying to gradually become proficient in these technically and manually complicated procedures. Getting y ...
Subregions of the human superior frontal gyrus and their connections
Subregions of the human superior frontal gyrus and their connections

... (rsFC) can reveal functional correlation between every two regions by evaluating the temporal coherence of the low frequency blood oxygen level dependent (BOLD) signals. The combination of these methods will simultaneously show both the anatomical and functional connection patterns of a brain area, ...
Responses of primate frontal cortex neurons during natural vocal
Responses of primate frontal cortex neurons during natural vocal

... neurons during natural, active communication for at least the following four reasons. First, this facet of marmoset communication has been extensively studied at the behavioral level (Chow et al. 2015; Miller et al. 2009a,b; Miller and Thomas 2012; Miller and Wang 2006; Morrill et al. 2013; Roy et a ...
Region-specific alterations of A-to-I RNA editing of
Region-specific alterations of A-to-I RNA editing of

... worldwide. According to a very recent report, over a million suicides are reported per year worldwide.1 A main risk factor for suicide is a psychiatric illness.2,3 Suicide is a complex multifactorial outcome and its biological basis remains insufficiently understood. Although neither a single gene no ...
An optical neural interface: in vivo control of rodent
An optical neural interface: in vivo control of rodent

... For example, in neuroscience, genetically targeted and temporally precise manipulation of neuronal activity would enable exploration of the causal function of individual neuron types in intact circuits. In the clinical setting, precise control over specific molecularly distinct cell types within int ...
Neurobilogy of Sleep
Neurobilogy of Sleep

... • The VLPO is an area in the hypothalamus containing neurons active during sleep. Most sleep-active neurons in the VLPO are believed to be active during both NREM and REM sleep • Many of the VLPO neurons are activated by sleepinducing factors including adenosine and prostaglandinD2. These neurons ar ...
Microstructure of the neocortex: Comparative aspects
Microstructure of the neocortex: Comparative aspects

... The appearance of the neocortex, its expansion, and its differentiation in mammals, represents one of the principal episodes in the evolution of the vertebrate brain. One of the fundamental questions in neuroscience is what is special about the neocortex of humans and how does it differ from that of ...
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Aging brain

Age is a major risk factor for most common neurodegenerative diseases, including Mild cognitive impairment, Alzheimer's disease, cerebrovascular disease, Parkinson's disease and Lou Gehrig's disease. While much research has focused on diseases of aging, there are few informative studies on the molecular biology of the aging brain (usually spelled ageing brain in British English) in the absence of neurodegenerative disease or the neuropsychological profile of healthy older adults. However, research does suggest that the aging process is associated with several structural, chemical, and functional changes in the brain as well as a host of neurocognitive changes. Recent reports in model organisms suggest that as organisms age, there are distinct changes in the expression of genes at the single neuron level. This page is devoted to reviewing the changes associated with healthy aging.
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