J Neurophysiol - University of Connecticut
... manipulated. They suffer, however, from their task specificity: a given stimulus usually reveals a very limited aspect of neural response preference, whether temporal (e.g., clicks), spectral (e.g., tones of varying frequency), or aural (e.g., best-frequency tones at varying interaural delay/level). ...
... manipulated. They suffer, however, from their task specificity: a given stimulus usually reveals a very limited aspect of neural response preference, whether temporal (e.g., clicks), spectral (e.g., tones of varying frequency), or aural (e.g., best-frequency tones at varying interaural delay/level). ...
Rapidly progressive Alzheimer`s disease features
... Genetic and environmental factors that increase the risk of late-onset Alzheimer disease are now well recognized but the cause of variable progression rates and phenotypes of sporadic Alzheimer’s disease is largely unknown. We aimed to investigate the relationship between diverse structural assembli ...
... Genetic and environmental factors that increase the risk of late-onset Alzheimer disease are now well recognized but the cause of variable progression rates and phenotypes of sporadic Alzheimer’s disease is largely unknown. We aimed to investigate the relationship between diverse structural assembli ...
ARTICULOS PUBLICADOS EN REVISTAS ELECTRÓNICAS: TRABAJO 1:
... pre-stimululs (200 ms) firing rate. Drug effects were calculated by comparing 2-min PSTHs at basal and post-drug periods. Data are expressed as the mean ± SEM. Statistical analysis was carried out using independent and paired Student’s t-tests. Statistical significance has been set at the 95% confid ...
... pre-stimululs (200 ms) firing rate. Drug effects were calculated by comparing 2-min PSTHs at basal and post-drug periods. Data are expressed as the mean ± SEM. Statistical analysis was carried out using independent and paired Student’s t-tests. Statistical significance has been set at the 95% confid ...
Document
... Research in Dr. Jaffe’s lab focuses on the hippocampal formation; a brain region important for certain aspects of learning and memory. It is also one of the first brain structures affected by Alzheimer's disease and medial temporal lobe epilepsy arises in the hippocampus, among other brain structure ...
... Research in Dr. Jaffe’s lab focuses on the hippocampal formation; a brain region important for certain aspects of learning and memory. It is also one of the first brain structures affected by Alzheimer's disease and medial temporal lobe epilepsy arises in the hippocampus, among other brain structure ...
Volitional enhancement of firing synchrony and oscillation
... i.e., oscillatory activity, of motor cortical neurons can be enhanced by operant conditioning. The study has succeeded to train monkeys to increase motor cortex low-gamma waves of local field potential (LFP) (Fig. 3). Single-neuron firing was recorded, and the enhancement of operantly conditioned os ...
... i.e., oscillatory activity, of motor cortical neurons can be enhanced by operant conditioning. The study has succeeded to train monkeys to increase motor cortex low-gamma waves of local field potential (LFP) (Fig. 3). Single-neuron firing was recorded, and the enhancement of operantly conditioned os ...
hoofdstuk 8 - VU-dare
... relation between specific RSNs and distinct dimensions of psychopathic traits. Moreover, brain dysfunctions in adult psychopaths may be heavily influenced by chronic substance abuse (Blair, 2004) or other aspects of an antisocial lifestyle, warranting their investigation in juveniles. In this respec ...
... relation between specific RSNs and distinct dimensions of psychopathic traits. Moreover, brain dysfunctions in adult psychopaths may be heavily influenced by chronic substance abuse (Blair, 2004) or other aspects of an antisocial lifestyle, warranting their investigation in juveniles. In this respec ...
Stimulation-Induced Functional Decoupling (SIFD)
... interactions become negligible with regards to individual neuronal dynamics. Thus, the network becomes «unwired» and neurons seem independent from one another. ...
... interactions become negligible with regards to individual neuronal dynamics. Thus, the network becomes «unwired» and neurons seem independent from one another. ...
Maruska & Tricas 2011
... Zhang and Delay, 2007). However, the hypothesis that these two extra-hypothalamic GnRH systems can directly modulate sensory processing in the brain has received only limited experimental testing (Kawai et al., 2010; Kinoshita et al., 2007), and little is known about how GnRH might influence other re ...
... Zhang and Delay, 2007). However, the hypothesis that these two extra-hypothalamic GnRH systems can directly modulate sensory processing in the brain has received only limited experimental testing (Kawai et al., 2010; Kinoshita et al., 2007), and little is known about how GnRH might influence other re ...
New Vistas on Amygdala Networks in Conditioned Fear
... in the acquisition of learned fear. Second, findings from animal studies have been confirmed in humans with functional magnetic resonance imaging (fMRI) techniques (Buchel et al. 1998; LaBar et al. 1998; Whalen et al. 1998), increasing the relevance of the animal model. Third, it is becoming increas ...
... in the acquisition of learned fear. Second, findings from animal studies have been confirmed in humans with functional magnetic resonance imaging (fMRI) techniques (Buchel et al. 1998; LaBar et al. 1998; Whalen et al. 1998), increasing the relevance of the animal model. Third, it is becoming increas ...
Cortical Involvement During Sustained Lower Limb Contractions
... identified and are key areas for potential cortical plasticity with impaired or enhanced leg function. Steadiness was altered by increasing cortical inputs (cognitive demand) especially in older adults whose motor performance was impaired and more variable than young. These results have important pe ...
... identified and are key areas for potential cortical plasticity with impaired or enhanced leg function. Steadiness was altered by increasing cortical inputs (cognitive demand) especially in older adults whose motor performance was impaired and more variable than young. These results have important pe ...
Unusual ultrastructural findings in dendrites of pyramidal
... virus. However, knowledge about the fine structure of dendrites in rabies infection is scarce. This work had the aim of studying the ultrastructure of dendrites in cortical pyramidal neurons of rabies-infected mice. Mice were inoculated intramuscularly with a street rabies virus of canine origin. Th ...
... virus. However, knowledge about the fine structure of dendrites in rabies infection is scarce. This work had the aim of studying the ultrastructure of dendrites in cortical pyramidal neurons of rabies-infected mice. Mice were inoculated intramuscularly with a street rabies virus of canine origin. Th ...
Postnatal growth and column spacing in cat primary visual cortex
... We used the 2-deoxyglucose (2-DG) technique (Sokoloff et al. 1977; Lwel and Singer 1993) to visualize ocular dominance columns in the primary visual cortex of awake kittens. A total of 23 animals (from 14 litters) from our institutes’ colonies was used. The experiments were performed with 3- to 6-w ...
... We used the 2-deoxyglucose (2-DG) technique (Sokoloff et al. 1977; Lwel and Singer 1993) to visualize ocular dominance columns in the primary visual cortex of awake kittens. A total of 23 animals (from 14 litters) from our institutes’ colonies was used. The experiments were performed with 3- to 6-w ...
Where is a Nose with Respect to a Foot? The Left
... even though a recent group study suggested that the left middle temporal cortex might be involved as well (Schwoebel and Coslett 2005). Moreover, fMRI studies associated both the middle temporal cortex and the posterior parietal cortex of the left hemisphere with tasks which may tap the BSD. For ins ...
... even though a recent group study suggested that the left middle temporal cortex might be involved as well (Schwoebel and Coslett 2005). Moreover, fMRI studies associated both the middle temporal cortex and the posterior parietal cortex of the left hemisphere with tasks which may tap the BSD. For ins ...
The Orbitofrontal Cortex and Reward
... convexity area is specifically involved in a short-term object memory is not yet clear, and a medial part of the frontal cortex may also contribute to this function (Kowalska et al., 1991). It should be noted that this short-term memory system for objects (which receives inputs from the temporal lob ...
... convexity area is specifically involved in a short-term object memory is not yet clear, and a medial part of the frontal cortex may also contribute to this function (Kowalska et al., 1991). It should be noted that this short-term memory system for objects (which receives inputs from the temporal lob ...
Dopamine in Schizophrenia
... in the treatment of amphetamine-induced psychosis and schizophrenia [neuroleptics or antipsychotic drugs (APDs)] decreased DA activity, and their clinical potency was correlated with their potency in blocking D2 receptors (Carlsson and Lindquist 1963; Creese et al. 1976; Hyttel et al. 1985; Farde et ...
... in the treatment of amphetamine-induced psychosis and schizophrenia [neuroleptics or antipsychotic drugs (APDs)] decreased DA activity, and their clinical potency was correlated with their potency in blocking D2 receptors (Carlsson and Lindquist 1963; Creese et al. 1976; Hyttel et al. 1985; Farde et ...
Effect of Methamphetamine Neurotoxicity on Learning- Arc Efferent Neurons
... the protein product of which (Arc, activity regulated cytoskeleton associated protein) is thought to be critically involved in synaptic modifications subserving learning and memory (Steward et al., 1998; Guzowski et al., 2000; 2001; Steward and Worley, 2001). The expression of Arc mRNA is correlated ...
... the protein product of which (Arc, activity regulated cytoskeleton associated protein) is thought to be critically involved in synaptic modifications subserving learning and memory (Steward et al., 1998; Guzowski et al., 2000; 2001; Steward and Worley, 2001). The expression of Arc mRNA is correlated ...
AN INTEGRATIVE THEORY OF LOCUS
... of the neural mechanisms underlying performance in simple decision-making tasks. We propose that within the context of a given task, phasic activity of the LC-NE system facilitates behavioral responses to the outcome of task-specific decision processes, filtering responses to irrelevant events.1 By se ...
... of the neural mechanisms underlying performance in simple decision-making tasks. We propose that within the context of a given task, phasic activity of the LC-NE system facilitates behavioral responses to the outcome of task-specific decision processes, filtering responses to irrelevant events.1 By se ...
Serotonin 1B Receptor Modulates Frequency Response Curves and
... Neuromodulatory signals such as serotonin are broadly released in the brain in response to changes in internal state (Trulson and Jacobs 1979, 1981) but transform the response properties of sensory neurons in highly specific ways (Hurley et al. 2004; Mooney et al. 1996; Xiang and Prince 2003). This ...
... Neuromodulatory signals such as serotonin are broadly released in the brain in response to changes in internal state (Trulson and Jacobs 1979, 1981) but transform the response properties of sensory neurons in highly specific ways (Hurley et al. 2004; Mooney et al. 1996; Xiang and Prince 2003). This ...
Wired for reproduction: Organization and Development of Sexually
... display appropriate solicitation behaviors and successfully copulate with conspecific males but have not ovulated. Males have similar requirements for physiological coordination; an individual that has mature sperm and is ready to impregnate a female will not get the chance if he displays agonistic ...
... display appropriate solicitation behaviors and successfully copulate with conspecific males but have not ovulated. Males have similar requirements for physiological coordination; an individual that has mature sperm and is ready to impregnate a female will not get the chance if he displays agonistic ...
Behavioral and Pathological Effects in the Rat
... from altered neurotransmission, mostly within the basal ganglia (reviewed by Cadet, 1989). The permanent nature of the syndrome suggested, however, that it would more likely be associated with permanent histopathological changes. Silverstaining data indicated that sparse axonal degeneration may occu ...
... from altered neurotransmission, mostly within the basal ganglia (reviewed by Cadet, 1989). The permanent nature of the syndrome suggested, however, that it would more likely be associated with permanent histopathological changes. Silverstaining data indicated that sparse axonal degeneration may occu ...
Appendix Basics of the Nervous System
... The neuron are hard working units of the brain. To function, the neurons require a great deal of energy to function, much of this energy comes from the food that we eat on a daily basis. To expend energy requires that the system store energy to be able to release it. Just as a flashlight requires st ...
... The neuron are hard working units of the brain. To function, the neurons require a great deal of energy to function, much of this energy comes from the food that we eat on a daily basis. To expend energy requires that the system store energy to be able to release it. Just as a flashlight requires st ...
Afferents to the Optic Tectum of the Leopard Frog: An HRP Study
... and proximal dendrites. Somata filled with diffuse product were frequently seen in the same areas as the vesicle filled neurons. These were probably due to incidental axonal damage at the injection site. Evidence for both retrograde and orthograde movement was seen in fiber pathways. Although no dif ...
... and proximal dendrites. Somata filled with diffuse product were frequently seen in the same areas as the vesicle filled neurons. These were probably due to incidental axonal damage at the injection site. Evidence for both retrograde and orthograde movement was seen in fiber pathways. Although no dif ...
Axonal conduction properties of antidromically identified neurons in
... anatomically known layer of origin. Axonal properties were most distinct for corticofugal axons projecting through the crus cerebri. Corticothalamic axons projecting to either VB or POm were more similar to each other in terms of laminar location and conduction properties, but could be distinguished ...
... anatomically known layer of origin. Axonal properties were most distinct for corticofugal axons projecting through the crus cerebri. Corticothalamic axons projecting to either VB or POm were more similar to each other in terms of laminar location and conduction properties, but could be distinguished ...