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Genetic Analysis of the Drosophila Ellipsoid Body
Genetic Analysis of the Drosophila Ellipsoid Body

... center for higher-order brain function in insects. It is an intricate neuropil composed of four substructures. Each substructure contains repeated neuronal elements which are connected by processes such that topography is maintained. Although the neuronal architecture has been described in several i ...
PDF of article - Janelia Research Campus
PDF of article - Janelia Research Campus

Comparing functional connectivity via thresholding correlations and
Comparing functional connectivity via thresholding correlations and

... regions of the brain show similar functional magnetic resonance imaging (fMRI) measurements over time, then we could say that they are functionally connected, even though there may be no direct neuronal connection between these two regions. We can extend this idea to any image measurements. For exam ...
Control of Wake and Sleep States
Control of Wake and Sleep States

... Sleep effects are mediated through IL-1 type receptor and TNF-55kDa receptor. TNF-alpha inhibits expression of clock genes. Extracellular ATP release associated with neurotransmitter release during waking prompts astrocytic production of IL-1 and TNF-alpha. Adminstration of IL-1 into DRN or LC induc ...
Overview Synaptic plasticity Synaptic strength
Overview Synaptic plasticity Synaptic strength

... • Probability of neurotransmitter release p Postsynaptically: • Maximal conductance g associated with one synaptic vesicle ...
Models of bodily expression perception
Models of bodily expression perception

... between the presence of movement and the emotional information (Pichon et al., 2008). Recent studies have used dynamic stimuli and have proven useful for better understanding the respective contribution of action and emotion-related components. A study by Grosbras and Paus (2006) showed that video c ...
Comparing the Functional Representations of Central and Border
Comparing the Functional Representations of Central and Border

Organization of Visual Inputs to the Inferior Temporal and Posterior
Organization of Visual Inputs to the Inferior Temporal and Posterior

... of the brain were examined for the presence of retrogradely labeled fluorescent cells. These sections were mounted directly from 0.45% saline as the brain was cut, dried at 37”C, and stored without coverslips in light-tight boxes placed in plastic bags at 4°C. Tissue preservation was aided by desicc ...
5655.full - Journal of Neuroscience
5655.full - Journal of Neuroscience

... sequence of events in each trial was as follows: blank screen (1 s), fixation cross (2 s), fractal (1.5 s), emotional stimulus (3 s), and fractal again (1.5 s). The same fractal was shown twice in a trial, once before the emotional stimulus and once afterward, to increase the likelihood of an associ ...
Acute and chronic effects of cannabinoids on human brain: gene-environment interactions
Acute and chronic effects of cannabinoids on human brain: gene-environment interactions

... Acute and chronic effects of cannabinoids on human brain: gene-environment interactions related to psychiatric disorders Albert Batalla Cases ...
Chapter 14: Integration of Nervous System Functions
Chapter 14: Integration of Nervous System Functions

... 2. loss of pain and thermal sensations below the injury on the right side 3. loss of fine touch and pressure sensations below the injury on the left side 4. loss of fine touch and pressure sensations below the injury on right side 5. loss of fine motor control on the right side below the injury 6. l ...
download file
download file

... innervation from the IC and projects to the primary auditory cortex to process conscious and complex, higher-order information, such as the biological relevance of the acoustic stimuli [3,22,40] (Fig. 1). In addition, part of the acoustic information received in the MG is sent directly to the amygda ...
Downloaded - Cisler Lab
Downloaded - Cisler Lab

... 3014 J. M. Cisler et al. evidence suggested that one mechanism by which TF-CBT enabled PTSD symptom reduction was through the functional reorganization of specific neural circuits involved in emotion regulation, then subsequent research might test whether pharmacological or behavioral adjuncts to TF ...
Serotonergic Integration of Circadian Clock and Ultradian Sleep
Serotonergic Integration of Circadian Clock and Ultradian Sleep

... 2009). Despite great advances in elucidating the genetic and molecular circadian mechanisms functioning within SCN cells (Takahashi et al., 2008), precisely how this SCN activity controls the circadian pattern of shorter sleep–wake cycles remains unclear, partly because of the many brain regions and ...
The functional asymmetry of auditory cortex is reflected
The functional asymmetry of auditory cortex is reflected

... logy probing the circuitry of visual cortex, the first area in which microcircuitry was examined in detail. The introduction of laser scanning photostimulation (LSPS) has made it possible to examine the microcircuitry in other cortical areas with high efficiency. LSPS uses the photorelease of caged ...
GABAergic Influence on Taste Information in the Central Gustatory
GABAergic Influence on Taste Information in the Central Gustatory

... presence of GABA receptors was also reported using transgenic mice which expressed enhanced green fluorescent protein (EGFP) in a subset of GABA containing neurons (Travers et al, 2007). Again, in this study, this subset of GABA receptors was found to be most dense in the ventral rNST. GABAB recept ...
Involvement of Tumor Necrosis Factor Alpha in Hippocampal
Involvement of Tumor Necrosis Factor Alpha in Hippocampal

... Jackson Black C-57 mice and TNF-KO on JB C-57 background mice were used in the study. The TNF-KO mice (Pasparakis et al., 1996) were generously provided by Professor George Kollias, Hellenic Pasteur Institute, Athens, Greece. Absence of the TNFα gene was confirmed by ploymerase chain reaction (PCR) ...
Neuroimaging and neuropsychological findings in
Neuroimaging and neuropsychological findings in

... orbitofrontal cortex, subgenual cingulate cortex, ventral striatum, the cerebellum and brainstem. CY-BOCS scores were negatively correlated with gray matter volumes in the anterior orbitofrontal, ventrolateral and dorsolateral regions [40] . Pediatric OCD has been investigated in the context of pedi ...
Long-term Aerobic Exercise Is Associated With Greater Muscle
Long-term Aerobic Exercise Is Associated With Greater Muscle

... ­feature of aging that contributes to frailty and disability in elderly adults (1). Muscle mass begins to decline at approximately age 25 (2) and is accompanied by similar reductions in maximal dynamic and isometric force of the upper and lower limbs (3–5). These strength changes compromise several ...
Fluorescent in situ hybridization technique for cell type identification
Fluorescent in situ hybridization technique for cell type identification

... (chapter 2.3). These two protocols use different procedures before the fluorescent detection steps, and are suitable for different types of tissues. But the fluorescent detection steps are essentially the same. In chapter 2.3, we also describe modification of the basic two-color ISH to triple ISH. I ...
Stimulus-Dependent Synchronization of Neuronal Responses in the
Stimulus-Dependent Synchronization of Neuronal Responses in the

... preferences for particular features of visual stimuli, but in general, the tuning is broad. Thus, even simple stimuli evoke responses in numerous neurons with differing but overlapping feature preferences, and it is commonly held that a particular feature is encoded in the pattern of graded response ...
A Critical Review of Secondary Neurodegeneration
A Critical Review of Secondary Neurodegeneration

... molecular structure that allows it to assume a large variety of configurations within the central nervous system, each of which appears to result in quite distinct biological effects [13,14]. This issue of specificity with respect to configuration state of amyloid-β is not simply academic matter for ...
Basics of electromagnetic field mapping
Basics of electromagnetic field mapping

... data we obtain, and how does it affect the scalp maps we construct form this data? The problem is very similar to the measurement and display of the height profile of a geographic landscape, where height is referred to as a difference against a reference level (e.g. the level of the sea) which is so ...
extrasynaptic glutamate does not reach the postsynaptic density
extrasynaptic glutamate does not reach the postsynaptic density

... receptors in the postsynaptic density (PSD), glutamate (Glu) could affect the synaptic transmission. We have tested this possibility in the hippocampal CA1 synapses of rats, either by applying exogenous Glu to the CA1 neurons or by disruption of Glu transporter activity. LGlu (400 AM) was directly a ...
Isn`t it ironic? Neural Correlates of Irony Comprehension in
Isn`t it ironic? Neural Correlates of Irony Comprehension in

... including possible roles of the medial prefrontal lobe, default mode network, inferior frontal gyri, mirror neurons, right cerebral hemisphere and a possible mediating role of schizotypal personality traits. We investigated the neural correlates of irony comprehension in schizophrenia by using event ...
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Aging brain

Age is a major risk factor for most common neurodegenerative diseases, including Mild cognitive impairment, Alzheimer's disease, cerebrovascular disease, Parkinson's disease and Lou Gehrig's disease. While much research has focused on diseases of aging, there are few informative studies on the molecular biology of the aging brain (usually spelled ageing brain in British English) in the absence of neurodegenerative disease or the neuropsychological profile of healthy older adults. However, research does suggest that the aging process is associated with several structural, chemical, and functional changes in the brain as well as a host of neurocognitive changes. Recent reports in model organisms suggest that as organisms age, there are distinct changes in the expression of genes at the single neuron level. This page is devoted to reviewing the changes associated with healthy aging.
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