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Splicing together sister chromatids
Splicing together sister chromatids

... a detailed analysis of intron-retaining transcripts or alternative splice selection in cells with impaired spliceosome function may eventually provide additional targets further linking splicing with the control of the cell division cycle. Cohesin plays additional roles in the DNA damage response, D ...
- Wiley Online Library
- Wiley Online Library

... Bacillus subtilis grows anaerobically by at least two different pathways, respiration using nitrate as an electron acceptor and fermentation in the absence of electron acceptors. Regulatory mechanisms have evolved allowing cells to shift to these metabolic capabilities in response to changes in oxyg ...
Evolutionary Potential and Requirements for Minimal Protocells
Evolutionary Potential and Requirements for Minimal Protocells

... to be internally consistent, of course, but there can be an arbitrary number of such definitions for life, for example. It is the use of the alternative definitions that makes the difference: some definitions are found helpful because they categorise natural phenomena in a way that is conducive to furt ...
a  version - SEA
a version - SEA

... shares 29-41 phams with each. 22 phams are shared among all of these phages, suggesting they may have a common evolutionary history. Most of these phages appear to be lytic, but we were able to isolate potential lysogens from SteveFrench that are immune to SteveFrench and Flakey but not to the other ...
Identification of a family of BspA like surface proteins of Entamoeba
Identification of a family of BspA like surface proteins of Entamoeba

... with the concept that these genes could have come to E. histolytica via lateral gene transfer from prokaryotes [8]. With the completion of the E. histolytica genome project, we used the InterProScan software (http://www.ebi.ac.uk/ InterProScan) to screen for additional E. histolytica sequences that ...
Expression of phosphofructokinase in Neisseria meningitidis
Expression of phosphofructokinase in Neisseria meningitidis

... Software) was used to design the forward (59-CAAGAAGACTTCCGGCAACA-39) and reverse oligonucleotide primers (59TGATAAGCGAAGCGCATCAG-39). Primers were synthesized by Sigma-Genosys. The forward primer anneals 55 bp upstream of the ATG start codon while the reverse primer anneals 79 bp downstream of the ...
Similarities between putative transport proteins of plant viruses
Similarities between putative transport proteins of plant viruses

... amino acid substitutions relative to the M isolate. Other tripartite virus sequences used were: the 31-7K polypeptide of TSV RNA3 (Cornelissen et al., 1984), the 3a polypeptides of BMV RNA3 (Ahlquist et al., 1981), and of CMV RNA3 strain Q (Davies & Symons, 1988). The sequence of proteins encoded by ...
Physiological adaptations of Saccharomyces cerevisiae evolved for
Physiological adaptations of Saccharomyces cerevisiae evolved for

... protein was Rpl7B, a component of the large subunit of the ribosome. This was the only ribosomal protein showing a significant change in expression of >1.5 fold in any direction. Rpl7B is highly similar to Rpl7A which shows no change in expression. The significance of this differential expression is ...
Cloning and functional characterization of temperature responsive
Cloning and functional characterization of temperature responsive

... Another reason of this potential in drought tolerance could be due to its high stomatal control enabling plants to minimize the transpiration rate by keeping also a high level of net CO2 assimilation under water stress conditions (Severino et al., 2012). These physiologic ...
Nuclear mitotic apparatus protein (NuMA): spindle association
Nuclear mitotic apparatus protein (NuMA): spindle association

... its globular head or tail domains may induce cells to become micronucleated. Moreover, expression of wild-type human NuMA in tsBN2 cells, in which the endogenous NuMA protein is normally degraded, resulting in micronuclei at a restrictive temperature, was sufficient to suppress the micronucleation p ...
Model key paper ppt presentation
Model key paper ppt presentation

... Give enough background information for your audience to understand key terms and concepts ...
Current Opinion in Plant Biology
Current Opinion in Plant Biology

... Inoculant bacteria are often applied in seed coatings. After sowing, the inoculant bacteria must be able to establish themselves in the rhizosphere at population densities sufficient to produce a beneficial effect. Therefore, efficient inoculant bacteria should survive in the rhizosphere, make use o ...
Localization of the prostaglandin F2 alpha receptor
Localization of the prostaglandin F2 alpha receptor

... cloned and sequenced. Deduced amino acid sequences were analyzed for homology to the human FP receptor sequences. For the experiments, cells at passages 2 to 4 were grown to confluence and harvested. mRNA was isolated using Dynals mRNA Direct system (Dynal A/S; Oslo, Norway) according to the manufac ...
Module 1 : Introduction to the study of man
Module 1 : Introduction to the study of man

... Oxidation of Amino Acids ...
Design and Evolution of Artificial M13 Coat Proteins
Design and Evolution of Artificial M13 Coat Proteins

... coat requires interactions between the positively charged cytoplasmic domain and the negatively charged DNA, and also, interactions between the central hydrophobic domains of adjacent P8 molecules. These interactions also maintain the integrity of the assembled virus (Marvin, 1998). P8 carboxy termi ...
Interaction of DNA with ribosomes in cell-free protein
Interaction of DNA with ribosomes in cell-free protein

... DNA, calf thymus DNA and neomycin sulphate were obtained from Serva, Heidelberg. (2-14C) thymine came from The Radiochemical Centre, Amersham. The amino acid mixture, uniformly 14C-labelled, was from New England Nuclear, Inc. Transfer RNA (yeast), the nucleoside triphosphates, and chloramphenicol (p ...
Lack of homology between two haloacetate dehalogenase genes
Lack of homology between two haloacetate dehalogenase genes

... The diversity of the dehalogenases may result from selection for micro-organismsable to degrade a variety of novel halogenated compounds. Enzyme evolution may be initiated by tandem duplication of a gene, followed by the accumulation of multiple mutations on either gene copy, which results in the cr ...
Jonathan Orsay MCAT Biology 7 edition 2007_161-240
Jonathan Orsay MCAT Biology 7 edition 2007_161-240

... leaves at the other. Lymph capillaries are like tiny fingers protruding into the tissues. To enter the lymph system, interstitial fluid flows between overlapping endothelial cells (Fig. 7-11). Large particles literally push their way between the cells into the lymph. The cells overlap in such a fash ...
Chapter 5. Homology 3D Structure Prediction Chapter 6. Ab Initio
Chapter 5. Homology 3D Structure Prediction Chapter 6. Ab Initio

... – Sequence-Structure alignments / Structures comparison: Threading or the use of a solved 3D protein structure to search for compatibilities of sequences with known 3D folds ...
Identification, cloning and sequence determination of genes specifying hexokinase A and B from yeast.
Identification, cloning and sequence determination of genes specifying hexokinase A and B from yeast.

... ratio of 1.1, characteristic of hexokinase B. These experiments sufficed to show that each of the two genes represented by these classes of plasmid clones specifies one of the hexokinase isozymes. Additional evidence for the assignment of the plasmid clones to the loci specifying hexokinase A and B ...
Identification of Antigenic Regions of Duck Hepatitis B Virus Core
Identification of Antigenic Regions of Duck Hepatitis B Virus Core

... which is closely related to the human virus, is a reference model for in vivo studies of hepadnaviral replication and for antiviral approaches testing, since the chronic infection of ducks mimics aspects of what occurs in the HBV long-term carrier state. It is also a pertinent model for studying the ...
Biochem Chapter 44 [4-20
Biochem Chapter 44 [4-20

... Heme is made from glycine and succinyl CoA, which are combined to form δ-aminovulinic acid (δ-ALA) by δ-ALA synthetase – page 829 bottom pic o δ-ALA synthetase needs pyridoxal phosphate from vitamin B6 (pyridoxine) o B6 deficiencies slow the rate of heme making, so that less heme is made, causing th ...
Applied and Environmental Microbiology
Applied and Environmental Microbiology

... tropici. Figure 4 shows the nodulation kinetics of the different citrate synthase mutants compared with the wild type. Both the chromosomal mutant (CFNE 150) and the double mutant (CFNE 160) have a large reduction in nodule number per plant; at 21 days these differences were highly significant (P , ...
Folic Acid and Its Receptors - OPUS
Folic Acid and Its Receptors - OPUS

... Folic acid, also known as folate or vitamin B9, is essential for various functions in the human body and life as we know it. Folate is the compound that occurs naturally in food, and folic acid is the synthetic form of this vitamin (1). Chemically speaking, folic acid has the hydrogen (H+) attached ...
The energy-less red blood cell is lost: erythrocyte
The energy-less red blood cell is lost: erythrocyte

... Hexokinase catalyzes the phosphorylation of glucose to G6P, using ATP as a phosphoryl donor (Figure 1). As the initial step of glycolysis, HK is one of the rate-limiting enzymes of this pathway. The activity of hexokinase is significantly higher in reticulocytes compared with mature red cells, in wh ...
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Endogenous retrovirus



Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.
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