Glutathione Breakthrough: Advancement in
... Glutathione (GSH) is one of the most critical molecules of the entire body. GSH plays an important role in antioxidant defense, nutrient metabolism and is key in a vast number of cellular processes including gene expression, DNA and protein synthesis, cell proliferation and apoptosis, signal transdu ...
... Glutathione (GSH) is one of the most critical molecules of the entire body. GSH plays an important role in antioxidant defense, nutrient metabolism and is key in a vast number of cellular processes including gene expression, DNA and protein synthesis, cell proliferation and apoptosis, signal transdu ...
Biological significance of structural differences between two highly
... ordered (Fig. 1B) and adopted a structure very similar to Mms2 [8] with an RMSD of 0.5 Å. This was expected given the high degree of protein sequence homology between the two Uevs (Fig. 1A). Like Mms2, Uev1D30 possesses a noncanonical Ubc fold that consists of an amino-terminal a-helix followed by f ...
... ordered (Fig. 1B) and adopted a structure very similar to Mms2 [8] with an RMSD of 0.5 Å. This was expected given the high degree of protein sequence homology between the two Uevs (Fig. 1A). Like Mms2, Uev1D30 possesses a noncanonical Ubc fold that consists of an amino-terminal a-helix followed by f ...
Bio 226: Cell and Molecular Biology
... most enter nucleus and kinase transcription factors • Slow responses are due to changes in gene expression • Many targets of PHY are transcription factors, eg PIF3 • Activate cascades of genes for photomorphogenesis ...
... most enter nucleus and kinase transcription factors • Slow responses are due to changes in gene expression • Many targets of PHY are transcription factors, eg PIF3 • Activate cascades of genes for photomorphogenesis ...
Evidence from glycine transfer RNA of a frozen accident at the dawn
... catalyzed by an ancestor of a self-splicing group I or II intron, for the following reason. The conservation of an intron insertion site between different organisms is often taken to imply descent from a common ancestor. For example, self-splicing group I introns found at the same position in leucin ...
... catalyzed by an ancestor of a self-splicing group I or II intron, for the following reason. The conservation of an intron insertion site between different organisms is often taken to imply descent from a common ancestor. For example, self-splicing group I introns found at the same position in leucin ...
Protein Structure Prediction Based on Neural Networks
... and knowledge of a protein’s 3D structure improves the analysis of protein functions, particularly for drug design [2]. Being aware of the 3D structure of a protein enables pharmacologists to select a binding protein to moderate its functions. Pharmacologists may choose a drug which is easy to synt ...
... and knowledge of a protein’s 3D structure improves the analysis of protein functions, particularly for drug design [2]. Being aware of the 3D structure of a protein enables pharmacologists to select a binding protein to moderate its functions. Pharmacologists may choose a drug which is easy to synt ...
Regulation of Cytochrome bd Expression in Mycobacterium
... Mycobacteria are Gram-positive and acid-fast bacteria, belonging to the phylum of Actinobacteria. Mycobacteria possess G + C rich genomes with a content of about 62-70% (24). They are considered to be obligate aerobes and have a rod-shaped appearance of about 0.3 - 0.5 µm in diameter and of variable ...
... Mycobacteria are Gram-positive and acid-fast bacteria, belonging to the phylum of Actinobacteria. Mycobacteria possess G + C rich genomes with a content of about 62-70% (24). They are considered to be obligate aerobes and have a rod-shaped appearance of about 0.3 - 0.5 µm in diameter and of variable ...
Introduction to the BLAST Suite and BLASTN
... The REFERENCE field contains details about the sequence origin and can include publications. Also present under FEATURES is information found elsewhere in the annotation (for example, organism) but it may include additional facts or partial analysis results. We’ll see this later when we examine sequ ...
... The REFERENCE field contains details about the sequence origin and can include publications. Also present under FEATURES is information found elsewhere in the annotation (for example, organism) but it may include additional facts or partial analysis results. We’ll see this later when we examine sequ ...
unit 2: mechanisms of inheritance
... DNA extraction labs are available from many print and online sources and are relatively simple to perform. They use • inexpensive materials (e.g., dish soap, salt [NaCl], ethanol, plant or animal tissue) • simple equipment (e.g., beakers, test tubes, mortar and pestle, glass rods, stir sticks) The D ...
... DNA extraction labs are available from many print and online sources and are relatively simple to perform. They use • inexpensive materials (e.g., dish soap, salt [NaCl], ethanol, plant or animal tissue) • simple equipment (e.g., beakers, test tubes, mortar and pestle, glass rods, stir sticks) The D ...
Identification of genomic features in the classification of loss
... Background: Alterations of a genome can lead to changes in protein functions. Through these genetic mutations, a protein can lose its native function (loss-of-function, LoF), or it can confer a new function (gain-of-function, GoF). However, when a mutation occurs, it is difficult to determine whethe ...
... Background: Alterations of a genome can lead to changes in protein functions. Through these genetic mutations, a protein can lose its native function (loss-of-function, LoF), or it can confer a new function (gain-of-function, GoF). However, when a mutation occurs, it is difficult to determine whethe ...
BIF CH4 5th proofs.qxd
... Because homology implies a common ancestor, it can also imply a common function or structure for two homologous proteins, which can be a useful pointer to function if one of the proteins is known only from its sequence. The operation of natural selection tends to result in the acceptance of mutation ...
... Because homology implies a common ancestor, it can also imply a common function or structure for two homologous proteins, which can be a useful pointer to function if one of the proteins is known only from its sequence. The operation of natural selection tends to result in the acceptance of mutation ...
Balancing between respiration and fermentation - UvA-DARE
... Inn addition to this, the two yeasts also differ in ADP/ATP translocation mechanism by the ADP/ATPP antiporter protein encoded by the AAC genes. In S. cerevisiae, three genes encoding thiss carrier have been identified, with different expression patterns depending on aerobic and anaerobicc condition ...
... Inn addition to this, the two yeasts also differ in ADP/ATP translocation mechanism by the ADP/ATPP antiporter protein encoded by the AAC genes. In S. cerevisiae, three genes encoding thiss carrier have been identified, with different expression patterns depending on aerobic and anaerobicc condition ...
View PDF
... that extend more than 10.000 bases with SQR. The main difference between the Watcut application for multiple sequences and SQR is that the first one requires the edition of the sequences before analysis while ours does not; thus, the input of sequences in SQR is easy and even allows the simple copy- ...
... that extend more than 10.000 bases with SQR. The main difference between the Watcut application for multiple sequences and SQR is that the first one requires the edition of the sequences before analysis while ours does not; thus, the input of sequences in SQR is easy and even allows the simple copy- ...
Predicting DNA-binding sites of proteins from amino acid sequence
... Background: Understanding the molecular details of protein-DNA interactions is critical for deciphering the mechanisms of gene regulation. We present a machine learning approach for the identification of amino acid residues involved in protein-DNA interactions. Results: We start with a Naïve Bayes c ...
... Background: Understanding the molecular details of protein-DNA interactions is critical for deciphering the mechanisms of gene regulation. We present a machine learning approach for the identification of amino acid residues involved in protein-DNA interactions. Results: We start with a Naïve Bayes c ...
Nucleotide sequence and structural organization of
... open reading frames (ORFs) covering 38 YOof the plasmid were identified. O R F l , from position 1638 to 2264, could encode a peptide of 208 amino acids with a molecular mass of 24.9 kDa. ORF2 begins at nucleotide 2260, overlaps the ORFl codon by four base pairs and extends to position 243 1 . I t h ...
... open reading frames (ORFs) covering 38 YOof the plasmid were identified. O R F l , from position 1638 to 2264, could encode a peptide of 208 amino acids with a molecular mass of 24.9 kDa. ORF2 begins at nucleotide 2260, overlaps the ORFl codon by four base pairs and extends to position 243 1 . I t h ...
univERsity oF copEnhAGEn
... ten encountered during this process, due to genotype-environment interactions [17]. Furthermore, resistance to some diseases is complex as they are quantitatively inherited making it difficult to achieve rapid progress through classical breeding [13]. In addition, breeding is complicated by the path ...
... ten encountered during this process, due to genotype-environment interactions [17]. Furthermore, resistance to some diseases is complex as they are quantitatively inherited making it difficult to achieve rapid progress through classical breeding [13]. In addition, breeding is complicated by the path ...
The DNA Binding Properties of Saccharomyces cerevisiae Rad51
... for the repair of double-strand DNA breaks caused by ionizing irradiation (2). Biochemical studies of Rad51 protein demonstrated that it shares similar properties to RecA protein, including ssDNA1-dependent ATPase activity, homologous pairing, and DNA strand exchange activity (3–5), and the formatio ...
... for the repair of double-strand DNA breaks caused by ionizing irradiation (2). Biochemical studies of Rad51 protein demonstrated that it shares similar properties to RecA protein, including ssDNA1-dependent ATPase activity, homologous pairing, and DNA strand exchange activity (3–5), and the formatio ...
Towards the construction of Escherichia coli cell
... Cell-free protein systems are described as the in vitro expression of recombinant proteins without the use of living cells. This approach uses a cell lysate containing a wide array of biological and chemical components for transcription, translation, protein folding, and energy metabolism; all requi ...
... Cell-free protein systems are described as the in vitro expression of recombinant proteins without the use of living cells. This approach uses a cell lysate containing a wide array of biological and chemical components for transcription, translation, protein folding, and energy metabolism; all requi ...
VAAM-Jahrestagung 2015 1.–4. März in Marburg/Lahn
... Behring and the Marburg virus. Both names are connected with the Hygiene-Institute of the Philipps-University that was founded in 1885 and whose first director was Max Rubner. R. Siegert, a long-time director (1957–1982) of this institute, succinctly summarized the history and impressive accomplishm ...
... Behring and the Marburg virus. Both names are connected with the Hygiene-Institute of the Philipps-University that was founded in 1885 and whose first director was Max Rubner. R. Siegert, a long-time director (1957–1982) of this institute, succinctly summarized the history and impressive accomplishm ...
Global transcriptional control by glucose and
... Clostridium difficile binary toxin (CDT), which is produced by 35% of C. difficile strains, has been recently shown to play a role in adherence to the host intestinal epithelial cells (11). Other factors, such as the adhesin Cwp66, the flagellum, the fibronectin-binding protein FbpA and the surface laye ...
... Clostridium difficile binary toxin (CDT), which is produced by 35% of C. difficile strains, has been recently shown to play a role in adherence to the host intestinal epithelial cells (11). Other factors, such as the adhesin Cwp66, the flagellum, the fibronectin-binding protein FbpA and the surface laye ...
Biosynthesis of estradiol. Cloning and characterization of rodent
... 17β-Hydroxysteroid dehydrogenases (17HSDs)/17-ketosteroid reductases (17KSRs) modulate the biological activity of certain estrogens and androgens by catalyzing dehydrogenase and reductase reactions between 17β-hydroxy and 17-ketosteroids. In the present study, cDNAs encoding mouse and rat 17HSD/KSR1 ...
... 17β-Hydroxysteroid dehydrogenases (17HSDs)/17-ketosteroid reductases (17KSRs) modulate the biological activity of certain estrogens and androgens by catalyzing dehydrogenase and reductase reactions between 17β-hydroxy and 17-ketosteroids. In the present study, cDNAs encoding mouse and rat 17HSD/KSR1 ...
- VU Research Repository
... One of the major yeast stressors during fermentation is ethanol accumulation. Ethanol stress is associated with reduced cell growth and viability, consequently lowering yeast productivity. Although the underlying causes of ethanol inhibition of cells are yet to be identified, it has been discovered ...
... One of the major yeast stressors during fermentation is ethanol accumulation. Ethanol stress is associated with reduced cell growth and viability, consequently lowering yeast productivity. Although the underlying causes of ethanol inhibition of cells are yet to be identified, it has been discovered ...
Supplementary Table 1: WormBase IDs and given
... following order with the DNA solution, 50μl of 2.5M CaCl2 and 20μl of 0.1M spermidine and then vigorously vortexed for 3 more minutes. The coated particles were pelleted to remove the supernatant, washed once with alcohol (as above) and re-suspended by vigorous vortexing in 100μl of alcohol. The su ...
... following order with the DNA solution, 50μl of 2.5M CaCl2 and 20μl of 0.1M spermidine and then vigorously vortexed for 3 more minutes. The coated particles were pelleted to remove the supernatant, washed once with alcohol (as above) and re-suspended by vigorous vortexing in 100μl of alcohol. The su ...
Herculex® I Product Overview
... rootworm. The European corn borer alone destroys an estimated $1 to $2 billion worth of corn each year. Insects cause many other forms of damage when they feed on parts of the corn plant, including breakage of the plant, eardrop and kernel damage. Damaged kernels can lead to growth of fungi, which m ...
... rootworm. The European corn borer alone destroys an estimated $1 to $2 billion worth of corn each year. Insects cause many other forms of damage when they feed on parts of the corn plant, including breakage of the plant, eardrop and kernel damage. Damaged kernels can lead to growth of fungi, which m ...