A Biocatalytic Henry Reaction-The Hydroxynitrile Lyase from Hevea
... absolute configuration of the product was determined to be S,[5] which is in agreement with the known stereopreference of HbHNL in cyanohydrin reactions. Although the nitroaldol reaction has been known for more than a century,[6] stereoselective protocols started to evolve only a few decades ago. In ...
... absolute configuration of the product was determined to be S,[5] which is in agreement with the known stereopreference of HbHNL in cyanohydrin reactions. Although the nitroaldol reaction has been known for more than a century,[6] stereoselective protocols started to evolve only a few decades ago. In ...
Chapter 9-Additions to Alkenes I
... stereoselective reaction can give two products, but one is obtained in higher proportion because of differences in transition state energies leading to the two products.) The 1,2-alkyl shift also occurs stereospecifically. The C–O bond is formed concerted with C–B bond breakage, so that if the B is ...
... stereoselective reaction can give two products, but one is obtained in higher proportion because of differences in transition state energies leading to the two products.) The 1,2-alkyl shift also occurs stereospecifically. The C–O bond is formed concerted with C–B bond breakage, so that if the B is ...
Addition of ketene to ethylene oxide
... important commercial applications of ethylene oxide is as an intermediate in the preparation of surface active agents • . This involves a reaction with long chain carboxylic acids to produce a molecule containing both hydrophobic and hydrophilic characteristics. Ethylene oxide undergoes attack by su ...
... important commercial applications of ethylene oxide is as an intermediate in the preparation of surface active agents • . This involves a reaction with long chain carboxylic acids to produce a molecule containing both hydrophobic and hydrophilic characteristics. Ethylene oxide undergoes attack by su ...
Provisional Curriculum for the Canadian Chemistry Contest (CCC
... measured, e.g by reference to changes in mass, volume, concentration or pH of a solution 6.11 find the rate of a reaction using the slope of a measured variable (mass, volume, concentration or pH of a solution) against time 6.12 identify the order of reaction with respect to a named reagent given th ...
... measured, e.g by reference to changes in mass, volume, concentration or pH of a solution 6.11 find the rate of a reaction using the slope of a measured variable (mass, volume, concentration or pH of a solution) against time 6.12 identify the order of reaction with respect to a named reagent given th ...
The Acid-Catalyzed Reaction of Acetic
... Wear gloves while mixing the reactants. Measure 1.6 mL of acetic anhydride into the short-neck roundbottomed flask from your microscale kit. Clamp the flask upright using the three-finger microclamp. Using a glass Pasteur pipet, cautiously add 3 drops of concentrated sulfuric acid, one drop at a tim ...
... Wear gloves while mixing the reactants. Measure 1.6 mL of acetic anhydride into the short-neck roundbottomed flask from your microscale kit. Clamp the flask upright using the three-finger microclamp. Using a glass Pasteur pipet, cautiously add 3 drops of concentrated sulfuric acid, one drop at a tim ...
Design and synthesis optimization of bis(β
... catalysts. One of the classical examples is aluminum alkoxide such as Al(Oi-‐Pr)3.[9] Although it was useful in determination of the polymerization mechanism, its activity was not satisfactory. In or ...
... catalysts. One of the classical examples is aluminum alkoxide such as Al(Oi-‐Pr)3.[9] Although it was useful in determination of the polymerization mechanism, its activity was not satisfactory. In or ...
Summary
... will contain nitrogen atoms, phenyl rings, and/or methyl groups, all of which can stabilize the metal center through various mechanisms. The substituents will also be sufficiently bulky so as to encourage interaction with the open coordination sites of the metal center. The synthesis of the pendant ...
... will contain nitrogen atoms, phenyl rings, and/or methyl groups, all of which can stabilize the metal center through various mechanisms. The substituents will also be sufficiently bulky so as to encourage interaction with the open coordination sites of the metal center. The synthesis of the pendant ...
Novel Brønsted-acidic ionic liquids based on benzothiazolium
... acids. In recent years, parallel to the rapid development of ILs, their applications in esterification have been extensively studied. For example, catalytic amounts of Brønsted-acidic ionic liquids promoted esterification, microwave-accelerated esterification in Brønsted-acidic ionic liquids and ult ...
... acids. In recent years, parallel to the rapid development of ILs, their applications in esterification have been extensively studied. For example, catalytic amounts of Brønsted-acidic ionic liquids promoted esterification, microwave-accelerated esterification in Brønsted-acidic ionic liquids and ult ...
Oxidation of Cyclohexanol to Cyclohexanone
... You are required to calculate a theoretical and a percent yield for this experiment. For instructions and examples on how to do this, see the examples in the Percent Yield Instruction sheet. Note that one of the starting materials was added as a neat liquid, the other material was added as an aqueou ...
... You are required to calculate a theoretical and a percent yield for this experiment. For instructions and examples on how to do this, see the examples in the Percent Yield Instruction sheet. Note that one of the starting materials was added as a neat liquid, the other material was added as an aqueou ...
KEY - Practice Qs
... (b) In terms of chemical properties, how are all organic acids alike? Conduct electricity, donate H+ (c) In terms of chemical properties, how are organic acids and alcohols different? Alcohols do NOT conduct electricty or donate H+ like acids do (d) In terms of structure, how are ketones and aldehyd ...
... (b) In terms of chemical properties, how are all organic acids alike? Conduct electricity, donate H+ (c) In terms of chemical properties, how are organic acids and alcohols different? Alcohols do NOT conduct electricty or donate H+ like acids do (d) In terms of structure, how are ketones and aldehyd ...
Exp`t 88 - Chemistry Courses
... round-bottomed flask from your microscale kit. Clamp the flask upright using the three-finger microclamp. Using a glass Pasteur pipet, cautiously add 3 drops of concentrated sulfuric acid, one drop at a time, letting the sulfuric acid run down the inside wall of the flask neck. Add 4 boiling chips a ...
... round-bottomed flask from your microscale kit. Clamp the flask upright using the three-finger microclamp. Using a glass Pasteur pipet, cautiously add 3 drops of concentrated sulfuric acid, one drop at a time, letting the sulfuric acid run down the inside wall of the flask neck. Add 4 boiling chips a ...
Prof_Elias_Inorg_lec_6
... even in hydrocarbon solvents. E.g. Ferrocene is soluble in hexane while Fe2+ as such is not. Outcome: a hydrocarbon soluble additive/catalyst ...
... even in hydrocarbon solvents. E.g. Ferrocene is soluble in hexane while Fe2+ as such is not. Outcome: a hydrocarbon soluble additive/catalyst ...
A Direct Access to 3-(2-Oxoalkyl)indoles via
... for C-C bond formation. More recently, we have found that AlCl3-induced acylation could be utilized as a novel route to 3-(2-oxoalkyl)indoles 3 by reacting 3-methylindole 1 with acyl chloride 2 under the Friedel-Crafts reaction condition (Scheme 1). To the best of our knowledge, this is the first ex ...
... for C-C bond formation. More recently, we have found that AlCl3-induced acylation could be utilized as a novel route to 3-(2-oxoalkyl)indoles 3 by reacting 3-methylindole 1 with acyl chloride 2 under the Friedel-Crafts reaction condition (Scheme 1). To the best of our knowledge, this is the first ex ...
Ring-closing metathesis
Ring-closing metathesis, or RCM, is a widely used variation of olefin metathesis in organic chemistry for the synthesis of various unsaturated rings via the intramolecular metathesis of two terminal alkenes, which forms the cycloalkene as the E- or Z- isomers and volatile ethylene.The most commonly synthesized ring sizes are between 5-7 atoms; however, reported syntheses include 45- up to 90- membered macroheterocycles. These reactions are metal-catalyzed and proceed through a metallacyclobutane intermediate. It was first published by Dider Villemin in 1980 describing the synthesis of an Exaltolide precursor, and later become popularized by Robert H. Grubbs and Richard R. Schrock, who shared the Nobel Prize in Chemistry, along with Yves Chauvin, in 2005 for their combined work in olefin metathesis. RCM is a favorite among organic chemists due to its synthetic utility in the formation of rings, which were previously difficult to access efficiently, and broad substrate scope. Since the only major by-product is ethylene, these reactions may also be considered atom economic, an increasingly important concern in the development of green chemistry.There are several reviews published on ring-closing metathesis.