Worked Example 18.1
... Next, look at the lists to see if any carbon atom is attached to four different groups. Of the three carbons, carbon 2 has four different groups, and lactic acid is therefore chiral. Fundamentals of General, Organic, and Biological Chemistry, 7e John McMurry, David S. Ballantine, Carl A. Hoeger, Vir ...
... Next, look at the lists to see if any carbon atom is attached to four different groups. Of the three carbons, carbon 2 has four different groups, and lactic acid is therefore chiral. Fundamentals of General, Organic, and Biological Chemistry, 7e John McMurry, David S. Ballantine, Carl A. Hoeger, Vir ...
Exam 1 from 2008
... a) Identify the functional groups in amoxicillin. (I've done one for you.) b) Put an asterisk by all sp2 hybridized carbon atoms. c) Provide the approximate value for the indicated bond angle. d) Although this is the structure that is usually drawn for amoxicillin (e.g., see Wikipedia), it is not ac ...
... a) Identify the functional groups in amoxicillin. (I've done one for you.) b) Put an asterisk by all sp2 hybridized carbon atoms. c) Provide the approximate value for the indicated bond angle. d) Although this is the structure that is usually drawn for amoxicillin (e.g., see Wikipedia), it is not ac ...
phenol - Knockhardy
... • the OH group is electron releasing • it increases the electron density of the delocalised system • it makes substitution much easier compared to benzene • the electron density is greatest at the 2,4 and 6 positions • substitution takes place at the 2,4 and 6 positions • phenol reacts readily with ...
... • the OH group is electron releasing • it increases the electron density of the delocalised system • it makes substitution much easier compared to benzene • the electron density is greatest at the 2,4 and 6 positions • substitution takes place at the 2,4 and 6 positions • phenol reacts readily with ...
Amino Acids Are the Building Blocks Of Proteins
... because they share the same “core” structure of NH3-CHR-COOH. Amino acids are different because the composition of the “R-group” is different for each of the 20 amino acids. A second way that the amino acid structures may be different is their stereochemistry. The arrangement of atoms around the alp ...
... because they share the same “core” structure of NH3-CHR-COOH. Amino acids are different because the composition of the “R-group” is different for each of the 20 amino acids. A second way that the amino acid structures may be different is their stereochemistry. The arrangement of atoms around the alp ...
Aldehyde Dehydrogenase Presentation
... Primary function: Converts aldehyde to carboxylic acid using Cystine and ...
... Primary function: Converts aldehyde to carboxylic acid using Cystine and ...
Experiment 7 — Nucleophilic Substitution
... Pre-lab preparation (1) Textbook Ch 8 covers the SN2 and SN1 mechanisms. Read/review as necessary. (2) Write the SN2 reaction of 1-bromobutane with NaI. Illustrate the electron flow with curved arrows. Since this is a one-step reaction, you've just written the mechanism. (3) Write a balanced equatio ...
... Pre-lab preparation (1) Textbook Ch 8 covers the SN2 and SN1 mechanisms. Read/review as necessary. (2) Write the SN2 reaction of 1-bromobutane with NaI. Illustrate the electron flow with curved arrows. Since this is a one-step reaction, you've just written the mechanism. (3) Write a balanced equatio ...
Full answers
... What is the stereochemistry at the tropic acid stereocentre? Write (R) or (S). Is tropine optically active? Explain your answer. Tropine is not optically active. It has no chiral centre and is identical to its mirror image. ...
... What is the stereochemistry at the tropic acid stereocentre? Write (R) or (S). Is tropine optically active? Explain your answer. Tropine is not optically active. It has no chiral centre and is identical to its mirror image. ...
U. of Kentucky Chemistry 535 Synthetic Organic Chemistry Spring
... You will need to work out the stereochemistry of the 1,2-addition product. iPr group is the biggest. Oxy-Cope has six-membered ring transition state. For partial credit figure out the 1,2-addition first using and draw out all transition states. Explain everything. ...
... You will need to work out the stereochemistry of the 1,2-addition product. iPr group is the biggest. Oxy-Cope has six-membered ring transition state. For partial credit figure out the 1,2-addition first using and draw out all transition states. Explain everything. ...
OXYGEN CONTAINING ORGANIC COMPOUNDS
... 1. The electrons on the alcohol oxygen are used to bond the carbon #1 to make an ether (red oxygen atom). 2. The hydrogen (green) is transferred to the carbonyl oxygen (green) to make a new alcohol group (green). http://www.elmhurst.edu/~chm/vchembook/700carbonyls.html ...
... 1. The electrons on the alcohol oxygen are used to bond the carbon #1 to make an ether (red oxygen atom). 2. The hydrogen (green) is transferred to the carbonyl oxygen (green) to make a new alcohol group (green). http://www.elmhurst.edu/~chm/vchembook/700carbonyls.html ...
Biological Molecules continued……
... 2. While cholesterol gets a lot of bad press it is vital to the body. Why is it important and to which group of biological molecules does it belong? 3. Both olive oil and butter are triglycerides. Why is olive oil liquid at room temperature while butter is solid? ...
... 2. While cholesterol gets a lot of bad press it is vital to the body. Why is it important and to which group of biological molecules does it belong? 3. Both olive oil and butter are triglycerides. Why is olive oil liquid at room temperature while butter is solid? ...
Iridoids and Valerian are not mentioned in the archive so please
... geranyl pyrophosphate (GPP) which is modified to form different acyclic, monocyclic, bi cyclic ,…….etc, derivative of monoterpenoid . In irregular monoterpenes we are not following this rule DMAPP & IPP, and we can use either two IPP or two DMAPP units without following head to tail condensation, an ...
... geranyl pyrophosphate (GPP) which is modified to form different acyclic, monocyclic, bi cyclic ,…….etc, derivative of monoterpenoid . In irregular monoterpenes we are not following this rule DMAPP & IPP, and we can use either two IPP or two DMAPP units without following head to tail condensation, an ...
Reductions of Carboxylic Acid Derivatives - IDC
... The use of lithium aluminum hydride (LiAlH4) and sodium borohydride (NaBH4) as reagents for the reduction of aldehydes and ketones to 1º and 2º-alcohols respectively has been noted. Of these, lithium aluminum hydride, often abbreviated LAH, is the most useful for reducing carboxylic acid derivatives ...
... The use of lithium aluminum hydride (LiAlH4) and sodium borohydride (NaBH4) as reagents for the reduction of aldehydes and ketones to 1º and 2º-alcohols respectively has been noted. Of these, lithium aluminum hydride, often abbreviated LAH, is the most useful for reducing carboxylic acid derivatives ...
Carbonyl Alpha-Substitution Reactions
... Formation of Enolate and Alkylation • Malonic ester (diethyl propanedioate) is easily converted into its enolate ion by reaction with sodium ethoxide in ethanol • The enolate is a good nucleophile that reacts rapidly with an alkyl halide to give an -substituted malonic ester ...
... Formation of Enolate and Alkylation • Malonic ester (diethyl propanedioate) is easily converted into its enolate ion by reaction with sodium ethoxide in ethanol • The enolate is a good nucleophile that reacts rapidly with an alkyl halide to give an -substituted malonic ester ...
Whitten, Davis, and Peck, General Chemistry, 6th Edition
... Recommended CER Experiments to accompany Hornback’s Organic Chemistry, Second Edition The table below matches sections from the book with recommended CER labs. Click on the experiment title to view a PDF of each lab. Go to www.CERLabs.com to search the complete CER database and to learn more about c ...
... Recommended CER Experiments to accompany Hornback’s Organic Chemistry, Second Edition The table below matches sections from the book with recommended CER labs. Click on the experiment title to view a PDF of each lab. Go to www.CERLabs.com to search the complete CER database and to learn more about c ...
Chemdraw B&W - Chemistry Courses
... compound and reduction of the nitro group • Reduction by catalytic hydrogenation over platinum is suitable if no other groups can be reduced • Iron, zinc, tin, and tin(II) chloride are effective in acidic solution ...
... compound and reduction of the nitro group • Reduction by catalytic hydrogenation over platinum is suitable if no other groups can be reduced • Iron, zinc, tin, and tin(II) chloride are effective in acidic solution ...
chemical equilibrium in a liquid phase
... substances described together with their various derivatives may all be transformed under the action of various reagents into P-phenylalanine-aceticacid. ...
... substances described together with their various derivatives may all be transformed under the action of various reagents into P-phenylalanine-aceticacid. ...
The Carboxylic Acid Group as an Effective Director of Ortho
... redistilled (bp 120.5-121.0 "C) NJV,N',"-tetramethyl-l,2-ethylenediamine and 100 mL of dry THF. The mixture was stirred magnetically and cooled to -90 "C. After consecutive addition of sec-butyllithium (0.110 mol, 80 mL of 1.4 M cyclohexanehexanes solution) and recrystallized benzoic acid (mp 122-12 ...
... redistilled (bp 120.5-121.0 "C) NJV,N',"-tetramethyl-l,2-ethylenediamine and 100 mL of dry THF. The mixture was stirred magnetically and cooled to -90 "C. After consecutive addition of sec-butyllithium (0.110 mol, 80 mL of 1.4 M cyclohexanehexanes solution) and recrystallized benzoic acid (mp 122-12 ...
Chapter 7 - Alkenes and Alkynes I less substituted alkene due to
... - Carrying out dehydrohalogenations with a bulky base, such as tert-butxide, favors the formation of the less substituted alkene due to sterics - When an elimination yields the less substituted alkene, it follows the Hofmann Rule - The anticoplanar transition state is preferred, but the syn coplanar ...
... - Carrying out dehydrohalogenations with a bulky base, such as tert-butxide, favors the formation of the less substituted alkene due to sterics - When an elimination yields the less substituted alkene, it follows the Hofmann Rule - The anticoplanar transition state is preferred, but the syn coplanar ...
Derivatization of polar compounds for GC - Sigma
... • Both degradation of reagents and derivatives themselves •Sufficiently dry samples prior to derivatization • This can be done with gentle heating and/or under a stream of dry nitrogen •If there is high humidity in the room, it may be helpful to store syringes, vials, etc. in a dry box •Silyl reagen ...
... • Both degradation of reagents and derivatives themselves •Sufficiently dry samples prior to derivatization • This can be done with gentle heating and/or under a stream of dry nitrogen •If there is high humidity in the room, it may be helpful to store syringes, vials, etc. in a dry box •Silyl reagen ...
File
... The effervescence caused by production of CO2 with carboxylic acids with solid Na2CO3 or aqueous NaHCO3 can be used as a functional group test for carboxylic acids ...
... The effervescence caused by production of CO2 with carboxylic acids with solid Na2CO3 or aqueous NaHCO3 can be used as a functional group test for carboxylic acids ...
- Deans Community High School
... a) Draw a labelled diagram of the apparatus that would be used to carry out this experiment in the aboratory. b) Oxidation of propan-1-ol yields a compound X, formula C3H6O, which can be further oxidised to compound Y, formula C3H6O2. i) Name and draw the structure of compound X. ii) Name and draw t ...
... a) Draw a labelled diagram of the apparatus that would be used to carry out this experiment in the aboratory. b) Oxidation of propan-1-ol yields a compound X, formula C3H6O, which can be further oxidised to compound Y, formula C3H6O2. i) Name and draw the structure of compound X. ii) Name and draw t ...
Chem 3.5 Answers #7
... Aldehydes are produced by the oxidation of primary alcohols using acidified potassium dichromate solution. The aldehyde must be distilled off as it is made or it will oxidise further, up to the carboxylic acid. Ketones are made by the same oxidation reaction with secondary alcohols, but they do not ...
... Aldehydes are produced by the oxidation of primary alcohols using acidified potassium dichromate solution. The aldehyde must be distilled off as it is made or it will oxidise further, up to the carboxylic acid. Ketones are made by the same oxidation reaction with secondary alcohols, but they do not ...
Petasis reaction
The Petasis reaction (alternatively called the Petasis borono–Mannich (PBM) reaction) is the chemical reaction of an amine, aldehyde, and vinyl- or aryl-boronic acid to form substituted amines.Reported in 1993 by Nicos Petasis as a practical method towards the synthesis of a geometrically pure antifungal agent, naftifine, the Petasis reaction can be described as a variation of the Mannich reaction. Rather than generating an enolate to form the substituted amine product, in the Petasis reaction, the vinyl group of the organoboronic acid serves as the nucleophile. In comparison to other methods of generating allyl amines, the Petasis reaction tolerates a multifunctional scaffold, with a variety of amines and organoboronic acids as potential starting materials. Additionally, the reaction does not require anhydrous or inert conditions. As a mild, selective synthesis, the Petasis reaction is useful in generating α-amino acids, and is utilized in combinatorial chemistry and drug discovery.