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Eagleman Ch 14. Motivation and Reward
Eagleman Ch 14. Motivation and Reward

...  It collects information about the internal state of the body and initiates responses.  There are many different nuclei within the hypothalamus.  Some seem to be predominantly input while others are mostly output nuclei. ...
Brain Stem Involvement in Immune and Aversive Challenge Jakob Paues
Brain Stem Involvement in Immune and Aversive Challenge Jakob Paues

... environment. This process is called homeostasis and has proved to be a very efficient mean to survive in a hostile external environment with shifting temperature, humidity and access to nutrients. An important aspect of the maintenance of homeostasis is the ability to recognise “friend from foe”. Th ...
Animal hormones
Animal hormones

... • Hormone receptors are proteins • Mutations can result in receptors with a lowered capacity for binding hormone, or none at all • Variations in receptor structure also affect responses to hormones; different tissues often have receptor proteins that respond in different ways to binding of the same ...
A part of the cholinergic fibers in mouse superior cervical ganglia
A part of the cholinergic fibers in mouse superior cervical ganglia

... VGluT2-immunoreactivity. Double immunoelectron microscopic observations will help whether the colocalization of GAD65 and VGluT2-immunoreactivities exists or not. The present study is the first report on VGluT2-immunoreactivity, and shows that ...
Effect of dopamine receptor stimulation on voltage
Effect of dopamine receptor stimulation on voltage

Thyroid hormone exerts site-specific effects on SRC
Thyroid hormone exerts site-specific effects on SRC

... interact with nuclear cofactors, which are requisite mediators of ligand-dependent transcriptional activation or repression of hormone responsive genes (Glass and Rosenfeld, 2000). Cofactors are believed to remodel local chromatin structure enabling nuclear receptors to activate or repress gene regu ...
The Elementary Nervous System Revisited1
The Elementary Nervous System Revisited1

... them from specialized receptive It is now seventy years since the publiepithelial cells in an outer body layer in cation of The Elementary Nervous System in which G. H. Parker (1919) summarized which muscle cells had already developed. views he had been developing over the pre- These primitive recep ...
Print this article - University of Toronto Journal of Undergraduate Life
Print this article - University of Toronto Journal of Undergraduate Life

... dystonic movements. In addition, involuntary writhing movements along the axis of a limb, termed athetosis, are idiosyncratic to levodopa-induced dyskinesias (LIDs) and are typically disordered and uncoordinated [10]. About 30% of PD patients suffer from dyskinesia after 4-6 years of levodopa therap ...
A Neuron Play - Web Adventures
A Neuron Play - Web Adventures

... potential is initiated. Furthermore, the magnitude of the action potential of a specific neuron is always the same. Neurons are separated by a gap (synapse) that the action potential cannot cross. Once the action potential reaches the end of an axon (its terminal), it stimulates the release of chemi ...
the nervous system
the nervous system

... To name the major parts of the nervous system. To describe the effects of the Nervous System on movement. Understanding the relationship of the nervous system with the other systems in the body. ...
Anatomy and regulation of the central melanocortin system
Anatomy and regulation of the central melanocortin system

... electrical activity of the NPY/AgRP neurons, and this property is maintained in hypothalamic slices used for electrophysiological studies42. The spontaneous firing rate of the NPY/AgRP neuron is generally quite low (0.5 Hz) and is elevated threefold by fasting. The activation can be prevented by adm ...
The neuropharmacology of impulsive behaviour
The neuropharmacology of impulsive behaviour

... findings have implicated the orbitofrontal cortex in impulsive action [20], whereas, to date, damage to this brain area was mainly found to produce or alter delay aversion [21– 24] and not impulsive action [25]. In addition, a role for limbic regions such as the habenula and hippocampus in impulsive ...
Types of Neuron and their function - Click here
Types of Neuron and their function - Click here

... The membranes of the sending and receiving cells are separated from each other by the fluid-filled synaptic gap. The signal cannot leap across the gap electrically. So, special chemicals called neurotransmitters have this role. As an electrical impulse travels down the "tail" of the cell, called the ...
Slide 8
Slide 8

... hormones once secreted into the bloodstream travel throughout the body until they reach their target, which could include not only other endocrine glands but also muscles and organs. The pituitary gland or master gland oversees all the endocrine responses. However, the pituitary gland takes orders f ...
Opposite Functions of Histamine H1 and H2 Receptors and H3
Opposite Functions of Histamine H1 and H2 Receptors and H3

... encoded in spike frequency and pattern of the inhibitory SNr projection neurons. SNr output intensity and pattern are often abnormal in movement disorders of basal ganglia origin. In Parkinson’s disease, histamine innervation and histamine H3 receptor expression in SNr may be increased. However, the ...
THE BASAL GANGLIA
THE BASAL GANGLIA

... akinesia also leads to a conspicuous lack of facial movements (mask like face). In addition, there is an increased muscular rigidity (rigidity results when agonist and antagonist muscles are activated simultaneously) and resting tremor (the tremor becomes quieter, if not entirely quiescent, once the ...
THE BASAL GANGLIA
THE BASAL GANGLIA

... akinesia also leads to a conspicuous lack of facial movements (mask like face). In addition, there is an increased muscular rigidity (rigidity results when agonist and antagonist muscles are activated simultaneously) and resting tremor (the tremor becomes quieter, if not entirely quiescent, once the ...
Action Representation in Mirror Neurons
Action Representation in Mirror Neurons

... strongest vision-only and motor responses. In conclusion, area F5 contains a population of neurons—audio-visual mirror neurons—that discharge not just to the execution or observation of a specific action but also when this action can only be heard. Multimodal neurons have been described in several c ...
E3R Game 1 Order That Student Copy
E3R Game 1 Order That Student Copy

... A. Receptors are ligand gated sodium ion channels which allow Na+ to enter the postsynaptic neuron (or muscle) and triggers an action potential in the postsynaptic neuron (or muscle contraction) B. Action potential gets to the end of the presynaptic axon C. The Ca++ triggers synaptic vesicles locate ...
Neurophysiology: Serotonin`s many meanings elude simple theories
Neurophysiology: Serotonin`s many meanings elude simple theories

... patience could be at least partially related to this (Miyazaki et al., 2014). Along with more direct findings, these results have collectively, if somewhat controversially, been discussed in terms of serotonin (putatively linked with punishment and ...
The Autonomic Nervous System
The Autonomic Nervous System

... • Most of the time these systems are ...
The Role of Dopamine and Its Dysfunction as a Consequence of
The Role of Dopamine and Its Dysfunction as a Consequence of

... to the nucleus accumbens through the amygdala and the hippocampus. The nigrostriatal pathway joins the substantia nigra with the neostriatum. The neuronal somata are located in the substantia nigra, and the axons of these neurons are ramified into the caudate nucleus and putamen. This pathway is als ...
resource - Fujisawa lab
resource - Fujisawa lab

... the activities of specific cell types and to examine the resulting effects. A recent innovation in experimental neuroscience has been the development of light-activated channels or pumps, derived from microbial photosynthetic systems, to modulate neural activity, known as opto­ genetics. The best-kn ...
The parasympathetic system
The parasympathetic system

... muscularis mucosae and the circular muscle of the muscularis externa. The myenteric (or Auerbach's) plexus is located between the circular and longitudinal layers of the muscularis externa. In addition to these two plexuses that have ganglia, three others'mucosal, deep muscular, and tertiary plexus' ...
Growth arrest specific gene 7 is associated with schizophrenia and
Growth arrest specific gene 7 is associated with schizophrenia and

... in the pathogenesis of human developmental brain diseases such as schizophrenia [9]. A recent paper reported that, in cultured olfactory neuroepithelial cells from individuals with schizophrenia, the stability of microtubules was increased [10]. Growth arrest specific gene 7 (GAS7) was initial ident ...
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Endocannabinoid system

The endocannabinoid system is a group of neuromodulatory lipids and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis and, broadly speaking, includes: The endogenous arachidonate-based lipids, anandamide (N-arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG); these are known as ""endocannabinoids"" and are physiological ligands for the cannabinoid receptors. Endocannabinoids are all eicosanoids. The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase. The cannabinoid receptors CB1 and CB2, two G protein-coupled receptors that are located in the central and peripheral nervous systems.The neurons, neural pathways, and other cells where these molecules, enzymes, and one or both cannabinoid receptor types are all colocalized form the endocannabinoid system.The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators for a variety of processes, including motor learning, appetite, and pain sensation, among other cognitive and physical processes. The localization of the CB1 receptor in the endocannabinoid system has a very large degree of overlap with the orexinergic projection system, which mediates many of the same functions, both physical and cognitive. Moreover, CB1 is colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1) receptors physically and functionally join together to form the CB1–OX1 receptor heterodimer.
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