ABSTRACT Title of dissertation: MOLECULAR MECHANISMS OF NEURONAL
... including the trafficking and function of neurotransmitter receptors and synaptic cell adhesion molecules (CAMs). In this dissertation, I investigated various distinct, yet related, mechanisms of neuronal development: the roles of synaptic adhesion-like molecules (SALMs) in neurite outgrowth and cel ...
... including the trafficking and function of neurotransmitter receptors and synaptic cell adhesion molecules (CAMs). In this dissertation, I investigated various distinct, yet related, mechanisms of neuronal development: the roles of synaptic adhesion-like molecules (SALMs) in neurite outgrowth and cel ...
Understanding Circuit Dynamics Using the Stomatogastric Nervous
... inhibitory connections (ACh, cholinergic; Glu, glutamatergic). (b) Schematic of the stomatogastric nervous system (STNS) and simultaneous intracellular (top four traces) and extracellular (bottom trace) recordings from H. americanus that show the typical triphasic pattern. CoG, commissural ganglion; ...
... inhibitory connections (ACh, cholinergic; Glu, glutamatergic). (b) Schematic of the stomatogastric nervous system (STNS) and simultaneous intracellular (top four traces) and extracellular (bottom trace) recordings from H. americanus that show the typical triphasic pattern. CoG, commissural ganglion; ...
Basal Ganglia: Internal Organization
... several dendrites that are initially spine free but then become densely laden with spines after the first bifurcation. They account for up to 97% of striatal neurons in rodents but a smaller proportion in primates. They utilize GABA as their major neurotransmitter and are subdivided into two major s ...
... several dendrites that are initially spine free but then become densely laden with spines after the first bifurcation. They account for up to 97% of striatal neurons in rodents but a smaller proportion in primates. They utilize GABA as their major neurotransmitter and are subdivided into two major s ...
Vasoactive intestinal polypeptide (VIP) expression and inhibitory
... developmental origins, gene expression, connectivity patterns and function. In addition to the multitude of parameters, they commonly overlap between categories. For example, a cell may have a basket-like morphology, express parvalbumin (PV) and have axo-axonic connectivity. Another cell might share ...
... developmental origins, gene expression, connectivity patterns and function. In addition to the multitude of parameters, they commonly overlap between categories. For example, a cell may have a basket-like morphology, express parvalbumin (PV) and have axo-axonic connectivity. Another cell might share ...
NEOCORTEX
... Fig. 12.1. Brains of modem vefebrates: goldfish (G), rat (R), cat (C), and Old World monkey ...
... Fig. 12.1. Brains of modem vefebrates: goldfish (G), rat (R), cat (C), and Old World monkey ...
Chemosensory pathways in the brainstem controlling
... Cardiorespiratory activity is controlled by a network of neurons located within the lower brainstem. The basic rhythm of breathing is generated by neuronal circuits within the medullary pre-Bötzinger complex, modulated by pontine and other inputs from cell groups within the medulla oblongata and th ...
... Cardiorespiratory activity is controlled by a network of neurons located within the lower brainstem. The basic rhythm of breathing is generated by neuronal circuits within the medullary pre-Bötzinger complex, modulated by pontine and other inputs from cell groups within the medulla oblongata and th ...
Temperature Integration at the AC Thermosensory Neurons
... tored with antenna (n ⫽ 7 neurons) (A) and without antenna (n ⫽ 11 neurons) (B) in w control flies. G-CaMP3.0 was Zeiss). During the experiments, the preparations expressed in the AC neurons using TrpA1 SH-Gal4. The AC neurons of the control flies were activated twice as the temperature were continu ...
... tored with antenna (n ⫽ 7 neurons) (A) and without antenna (n ⫽ 11 neurons) (B) in w control flies. G-CaMP3.0 was Zeiss). During the experiments, the preparations expressed in the AC neurons using TrpA1 SH-Gal4. The AC neurons of the control flies were activated twice as the temperature were continu ...
Gene Section TSHR (thyroid stimulating hormone receptor) Atlas of Genetics and Cytogenetics
... anterior pituitary gland and is the main regulator of thyroid gland growth and development. Binding of TSH to TSHR stimulates thyroid epithelial cell proliferation, and regulates the expression of differentiation markers such as thyroglobulin, thyroperoxidase and the sodium iodide symporter (NIS), n ...
... anterior pituitary gland and is the main regulator of thyroid gland growth and development. Binding of TSH to TSHR stimulates thyroid epithelial cell proliferation, and regulates the expression of differentiation markers such as thyroglobulin, thyroperoxidase and the sodium iodide symporter (NIS), n ...
A Split-LexA-based Concatenate Expression System for
... independently targeted recombinase, such as the yeast flipase or bacteriophage cre enzyme (BOHM et al. 2010). Because excision is irreversible, transgene expression in these systems reflects the cumulative pattern of activation of the recombinase over the developmental history of the organism. Such ...
... independently targeted recombinase, such as the yeast flipase or bacteriophage cre enzyme (BOHM et al. 2010). Because excision is irreversible, transgene expression in these systems reflects the cumulative pattern of activation of the recombinase over the developmental history of the organism. Such ...
identification of cell types in brain slices of the inferior colliculus
... of the dendritic tree. 9,22,25,33,51 The principal neuron is discshaped (called the ¯at neuron in rats) with dendrites that parallel the ®bro-dendritic laminae. A second, less common neuron with a different dendritic morphology is also found in all species studied (e.g. the less-¯at neuron in the ra ...
... of the dendritic tree. 9,22,25,33,51 The principal neuron is discshaped (called the ¯at neuron in rats) with dendrites that parallel the ®bro-dendritic laminae. A second, less common neuron with a different dendritic morphology is also found in all species studied (e.g. the less-¯at neuron in the ra ...
Vesicular glutamate transporter 3
... ter of serotonergic neurons, whereas the DRDSh consists of scattered serotonergic neurons in the surrounding regions (Abrams et al., 2005; Lowry et al., 2008). The rat DR has, however, been indicated to contain a substantial number of nonserotonergic neurons (Descarries et al., 1982). Numerous studi ...
... ter of serotonergic neurons, whereas the DRDSh consists of scattered serotonergic neurons in the surrounding regions (Abrams et al., 2005; Lowry et al., 2008). The rat DR has, however, been indicated to contain a substantial number of nonserotonergic neurons (Descarries et al., 1982). Numerous studi ...
Somatodendritic dopamine release - Philosophical Transactions of
... pars compacta project via the medial forebrain bundle to the dorsal striatum (caudate putamen), and DA neurons in the adjacent ventral tegmental area project to the ventral striatum (nucleus accumbens) and prefrontal cortex. In addition to classical vesicular release from axons, midbrain DA neurons ...
... pars compacta project via the medial forebrain bundle to the dorsal striatum (caudate putamen), and DA neurons in the adjacent ventral tegmental area project to the ventral striatum (nucleus accumbens) and prefrontal cortex. In addition to classical vesicular release from axons, midbrain DA neurons ...
NUCLEI-SPECIFIC RESPONSE TO PAIN IN THE BED NUCLEUS OF THE By
... colleagues developed a transgenic mouse that self-expressed a wheat germ agglutinin tracer driven by the Nav1.8 sodium channel gene. This type of channel is expressed exclusively on non-peptidergic C-fibres (Julius & McCleskey, 2006). Because the tracer was expressed only in non-peptidergic C-fibre ...
... colleagues developed a transgenic mouse that self-expressed a wheat germ agglutinin tracer driven by the Nav1.8 sodium channel gene. This type of channel is expressed exclusively on non-peptidergic C-fibres (Julius & McCleskey, 2006). Because the tracer was expressed only in non-peptidergic C-fibre ...
Sensitization of the Trigeminal Sensory System During Different
... (TNC) may change during the different phases of the rat estrous cycle, but none have been performed in an experimental paradigm for migraine headache. Methods.—Sixty-one cycling female Sprague–Dawley rats were used for these experiments. The stage of the estrous cycle of each animal was identified b ...
... (TNC) may change during the different phases of the rat estrous cycle, but none have been performed in an experimental paradigm for migraine headache. Methods.—Sixty-one cycling female Sprague–Dawley rats were used for these experiments. The stage of the estrous cycle of each animal was identified b ...
Kalirin, a Multifunctional Rho Guanine Nucleotide Exchange Factor
... isoforms in rat hippocampus Before evaluating the consequences of eliminating Kalirin expression in hippocampal pyramidal neurons, we first wanted to determine which isoforms were expressed in these cells during early postnatal development. Western blot analysis of hippocampal extracts with polyclon ...
... isoforms in rat hippocampus Before evaluating the consequences of eliminating Kalirin expression in hippocampal pyramidal neurons, we first wanted to determine which isoforms were expressed in these cells during early postnatal development. Western blot analysis of hippocampal extracts with polyclon ...
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... initiate the asymmetric expression of the TGFb ligand Nodal to coordinate visceral and brain asymmetry (Bisgrove et al., 2003; Liang et al., 2000; McGrath and Brueckner, 2003). In C. elegans AWC asymmetry, calcium also plays a role (Fig. 2). Prior to their interaction, the two AWC olfactory neurons ...
... initiate the asymmetric expression of the TGFb ligand Nodal to coordinate visceral and brain asymmetry (Bisgrove et al., 2003; Liang et al., 2000; McGrath and Brueckner, 2003). In C. elegans AWC asymmetry, calcium also plays a role (Fig. 2). Prior to their interaction, the two AWC olfactory neurons ...
Andrea Kádár
... central regulators of the hypothalamus-pituitary-thyroid (HPT) axis. These neurosecretory neurons are located in the hypothalamic paraventricular nucleus (PVN) and their axons terminate outside the blood-brain barrier (BBB) in the external zone of the median eminence (ME) where TRH is secreted to th ...
... central regulators of the hypothalamus-pituitary-thyroid (HPT) axis. These neurosecretory neurons are located in the hypothalamic paraventricular nucleus (PVN) and their axons terminate outside the blood-brain barrier (BBB) in the external zone of the median eminence (ME) where TRH is secreted to th ...
- CUNY Academic Works
... There are many people I’d like to thank for supporting me over the course of my work that have enabled me to complete this dissertation. I am especially grateful to my mentor, Dr. Robert Ranaldi. You had confidence in a young undergraduate student that approached you in your Behavioral Neuroscience ...
... There are many people I’d like to thank for supporting me over the course of my work that have enabled me to complete this dissertation. I am especially grateful to my mentor, Dr. Robert Ranaldi. You had confidence in a young undergraduate student that approached you in your Behavioral Neuroscience ...
involvement of the bed nucleus of the stria terminalis activated by
... bed nucleus of the stria terminalis (BST) are key structures of the extended amygdala, which is suggested to be involved in drug addiction and reward. We have previously reported that the Ce plays a crucial role in the negative affective component of morphine withdrawal. In the present study, we exa ...
... bed nucleus of the stria terminalis (BST) are key structures of the extended amygdala, which is suggested to be involved in drug addiction and reward. We have previously reported that the Ce plays a crucial role in the negative affective component of morphine withdrawal. In the present study, we exa ...
The functional anatomy of basal ganglia disorders
... isocortex ~4. The neurotransmitter of the corti- intruding into the normal flow of motor activity. In costriatal afferents is probably glutamate ~s. The addition, all these abnormal movements share a only other basal ganglia structure to receive signifi- common pharmacology in that the abnormal move ...
... isocortex ~4. The neurotransmitter of the corti- intruding into the normal flow of motor activity. In costriatal afferents is probably glutamate ~s. The addition, all these abnormal movements share a only other basal ganglia structure to receive signifi- common pharmacology in that the abnormal move ...
The psychophisiology of pain: a literature review - Reciis
... reticular formation, amygdaloid complex and hypothalamus among others (ALMEIDA et al., 2004). The transmission of nociceptive information to the higher centers occurs through the anterolateral tract of the spinal cord. The principal pathways of pain in the CNS are the spinothalamic, reticulospinal a ...
... reticular formation, amygdaloid complex and hypothalamus among others (ALMEIDA et al., 2004). The transmission of nociceptive information to the higher centers occurs through the anterolateral tract of the spinal cord. The principal pathways of pain in the CNS are the spinothalamic, reticulospinal a ...
Sorting and convergence of primary olfactory axons are
... we screened for expression of molecules that are localised to distinct neuronal cell types in the olfactory bulb. The FCM lacked expression of Pbx-1 (Fig. 2J), a global marker of many different olfactory bulb neurons in wild-type mice (Redmond et al., 1996; Fig. 2G). Reelin (Fig. 2H) and Id2 (Fig. 2 ...
... we screened for expression of molecules that are localised to distinct neuronal cell types in the olfactory bulb. The FCM lacked expression of Pbx-1 (Fig. 2J), a global marker of many different olfactory bulb neurons in wild-type mice (Redmond et al., 1996; Fig. 2G). Reelin (Fig. 2H) and Id2 (Fig. 2 ...
Chapter 2 Reivew of Lierature
... 1995) which are involved in the rewarding effects of nicotine. These behavioral abnormalities develop gradually and progressively during a course of repeated exposure to a drug of abuse, and can persist for months or years after discontinuation of drug use. As a result, drug addiction can be conside ...
... 1995) which are involved in the rewarding effects of nicotine. These behavioral abnormalities develop gradually and progressively during a course of repeated exposure to a drug of abuse, and can persist for months or years after discontinuation of drug use. As a result, drug addiction can be conside ...
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... system. The concentration gradient of each of these ions across the membrane helps determine the voltage of the membrane potential. Second, the quantitative importance of each of the ions in determining the voltage is proportional to the membrane permeability for that particular ion. That is, if th ...
... system. The concentration gradient of each of these ions across the membrane helps determine the voltage of the membrane potential. Second, the quantitative importance of each of the ions in determining the voltage is proportional to the membrane permeability for that particular ion. That is, if th ...