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UtroUp is a novel six zinc finger artificial transcription factor that
UtroUp is a novel six zinc finger artificial transcription factor that

... factors that are capable of binding and activating transcription from promoter “A” of both the human and mouse utrophin genes [18-23]. Zinc finger domains have been shown to be optimal building blocks for generating artificial transcription factors due to their versatility and modularity [24,25]. In ...
8 7 Mutations
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... •Mutation = the alteration of an organism’s DNA!! •A malfunction during the process of meiosis •From exposure to a physical or a chemical agent, a mutagen. •Can be a •change in one base pair •insertion OR deletion of large segments of DNA ...
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... bacteria that took up the plasmid was then separated from the others using antibiotic resistance provided by another gene that was introduced at the same time. 6. The genetically altered bacteria can now be cultured on a large scale. The will secrete insulin, which will then be extracted, purified, ...
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DNA Bonds

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Can pseudocomplementary peptide nucleic acid nucleases

... short stretch of amino acids that mediates the transport of the nuclear proteins into the nucleus. In theory, the binding of two heterodimers of designed pcPNAN hybrid molecules to the DNA target sequences results in FokI dimerization and subsequent DNA cleavage, and induction of a DNA double strand ...
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Zinc finger nuclease

Zinc-finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain. Zinc finger domains can be engineered to target specific desired DNA sequences and this enables zinc-finger nucleases to target unique sequences within complex genomes. By taking advantage of endogenous DNA repair machinery, these reagents can be used to precisely alter the genomes of higher organisms.
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