Medicinal Plants
... volatile oils, gums, tannins, etc. Some of these are powerful poisons if administered indiscriminately, while others are dangerously habit-forming. Even the most dangerous drugs can be of value to human beings, if judiciously employed. The active principles of plant drugs are commonly more concentra ...
... volatile oils, gums, tannins, etc. Some of these are powerful poisons if administered indiscriminately, while others are dangerously habit-forming. Even the most dangerous drugs can be of value to human beings, if judiciously employed. The active principles of plant drugs are commonly more concentra ...
The Successful Treatment of Opioid Withdrawal
... serotonin in opioid withdrawal (4,6-9), so too are studies that try to disprove its significance (10). Although 5-hydroxytryptophan (5-HTP) has not been studied in direct relation to relieving opioid withdrawal-induced muscle spasms, it has been shown to be an effective treatment of serotonin deplet ...
... serotonin in opioid withdrawal (4,6-9), so too are studies that try to disprove its significance (10). Although 5-hydroxytryptophan (5-HTP) has not been studied in direct relation to relieving opioid withdrawal-induced muscle spasms, it has been shown to be an effective treatment of serotonin deplet ...
Document
... However, when ingestion is within the usual range, fetal phenylalanine levels are far below toxic levels. Thus, moderate ingestion of aspartame (e.g. no more than 1 liter of diet soda per day) during pregnancy appears to pose little risk of fetal toxicity. ...
... However, when ingestion is within the usual range, fetal phenylalanine levels are far below toxic levels. Thus, moderate ingestion of aspartame (e.g. no more than 1 liter of diet soda per day) during pregnancy appears to pose little risk of fetal toxicity. ...
New Insights into the Statin-Cholesterol Controversy
... on exercise capacity and mitochondrial function: We used to think that there were very few side effects associated with this drug, but the truth is, up to 20 percent of statin users have experienced serious side effects like muscle pain, damage, and aching or high muscle enzymes. Statins can also po ...
... on exercise capacity and mitochondrial function: We used to think that there were very few side effects associated with this drug, but the truth is, up to 20 percent of statin users have experienced serious side effects like muscle pain, damage, and aching or high muscle enzymes. Statins can also po ...
Adverse Cardiovascular Events Temporally Associated With Ma
... Drug Administration, which included clinical records, investigative reports, and autopsy reports related to ma huang use. The main outcome measurements were stroke, myocardial infarction, and sudden death. • Results: From 1995 to 1997, 926 cases of possible ma huang toxicity were reported to the Foo ...
... Drug Administration, which included clinical records, investigative reports, and autopsy reports related to ma huang use. The main outcome measurements were stroke, myocardial infarction, and sudden death. • Results: From 1995 to 1997, 926 cases of possible ma huang toxicity were reported to the Foo ...
HU 210: A Potent Tool for Investigations of the Cannabinoid System
... the cannabimimetic activity (92). A lysine residue of the CB receptor is critical for receptor recognition by HU 210, as well as by CP 55,940 ((–)-cis-3-[(2-hydroxy-4-)(1,1-dimethylheptyl)phenyl]-trans-4-[3-hydroxypropyl]cyclohexanol) and ANA [(allZ)-N-(2hydroxyethyl)-5,8,11,14-eicosatetraenamide] b ...
... the cannabimimetic activity (92). A lysine residue of the CB receptor is critical for receptor recognition by HU 210, as well as by CP 55,940 ((–)-cis-3-[(2-hydroxy-4-)(1,1-dimethylheptyl)phenyl]-trans-4-[3-hydroxypropyl]cyclohexanol) and ANA [(allZ)-N-(2hydroxyethyl)-5,8,11,14-eicosatetraenamide] b ...
Drug
... The drug can have local effects - Epinephrine for asthma. The drug can have systemic effects - general anesthetics Large surface area, limited thickness of pulmonary membrane and high blood flow allow for almost instant absorption by diffusion Avoid first pass effect Disadvantages: Administration is ...
... The drug can have local effects - Epinephrine for asthma. The drug can have systemic effects - general anesthetics Large surface area, limited thickness of pulmonary membrane and high blood flow allow for almost instant absorption by diffusion Avoid first pass effect Disadvantages: Administration is ...
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington
... Ensure that the patient knows the correct time intervals for inhalers Provide a spacer if the patient has difficulty coordinating breathing with inhaler ...
... Ensure that the patient knows the correct time intervals for inhalers Provide a spacer if the patient has difficulty coordinating breathing with inhaler ...
Hallucinogens - public.coe.edu
... Substances whose primary effect is to cause perceptual and cognitive distortions without producing a state of toxic delirium o Most are synthesized by plants or have ...
... Substances whose primary effect is to cause perceptual and cognitive distortions without producing a state of toxic delirium o Most are synthesized by plants or have ...
Selective Serotonin Reuptake Inhibitor Toxicity And Serotonin
... major depressive disorder each year and of these, 12 million to 18 million are treated with antidepressants. The exact cause of depression is still not known, although there is strong suspicion that it is inheritable. One theory is that people who are depressed have alterations in brain serotonin le ...
... major depressive disorder each year and of these, 12 million to 18 million are treated with antidepressants. The exact cause of depression is still not known, although there is strong suspicion that it is inheritable. One theory is that people who are depressed have alterations in brain serotonin le ...
Monoamine Oxidase Inhibitors (MAOIs)
... Most cases of major depression can be treated successfully, usually with medication, psychotherapy, or both. The combination of psychotherapy and antidepressants is very effective in treating moderate to severe depression. The medications improve mood, sleep, energy, and appetite, while therapy stre ...
... Most cases of major depression can be treated successfully, usually with medication, psychotherapy, or both. The combination of psychotherapy and antidepressants is very effective in treating moderate to severe depression. The medications improve mood, sleep, energy, and appetite, while therapy stre ...
Drug Design, Testing, Manufacturing, and Marketing
... with all of its genes and DNA had been mapped through the Human Genome Project. Also, there are approximately 300 micro RNAs in the human genome that control different groups of genes and their activities. Researchers have already designed chemicals known as antagomirs that bind to specific micro RN ...
... with all of its genes and DNA had been mapped through the Human Genome Project. Also, there are approximately 300 micro RNAs in the human genome that control different groups of genes and their activities. Researchers have already designed chemicals known as antagomirs that bind to specific micro RN ...
Click here for handout
... adolescents may be reluctant to disclose recreational drug use. The fundamental principles of serotonin syndrome management remain unchanged in pediatrics. ...
... adolescents may be reluctant to disclose recreational drug use. The fundamental principles of serotonin syndrome management remain unchanged in pediatrics. ...
Cover 1 - Fast Facts
... Cigarette smoking is one of the most significant preventable causes of death and illness in the world. It accounts for some 400 000 deaths per year in the USA, approximately 100 000 in the UK and 4.9 million worldwide. In industrialized countries cigarette smoking accounts for 12–13% of life-years l ...
... Cigarette smoking is one of the most significant preventable causes of death and illness in the world. It accounts for some 400 000 deaths per year in the USA, approximately 100 000 in the UK and 4.9 million worldwide. In industrialized countries cigarette smoking accounts for 12–13% of life-years l ...
Effects of chronic d-amphetamine administration on the reinforcing
... Ling 2005). Although no medication has been approved by the Food and Drug Administration for clinical use, encouraging results have been observed with several compounds. One approach, agonist therapy, has been effective in the treatment of heroin and nicotine dependence (e.g., Kreek 2000; Silagy et ...
... Ling 2005). Although no medication has been approved by the Food and Drug Administration for clinical use, encouraging results have been observed with several compounds. One approach, agonist therapy, has been effective in the treatment of heroin and nicotine dependence (e.g., Kreek 2000; Silagy et ...
Tubular Secretion active transport - University of California, Berkeley
... a. Basis for insult: H+ or HCO3Caused by ingestion of alkaline drugs; excessive vomiting; increase Na+ delivery to distal tubule (increases H+ secretion & loss); low plasma K+; excessive aldosterone. b. Effects and diagnosis: pH and HCO3c. Immediate compensation: high pH slows respiratory dri ...
... a. Basis for insult: H+ or HCO3Caused by ingestion of alkaline drugs; excessive vomiting; increase Na+ delivery to distal tubule (increases H+ secretion & loss); low plasma K+; excessive aldosterone. b. Effects and diagnosis: pH and HCO3c. Immediate compensation: high pH slows respiratory dri ...
Sample Chapter
... has accompanying package insert recommendation for dosage alterations. No age-related differences in raloxifene pharmacokinetics have been identified, but cautionary dosing is advised in both moderate-to-severe renal impairment and in hepatic impairment.38 Nonsteroidal anti-inflammatory drugs (NSAID ...
... has accompanying package insert recommendation for dosage alterations. No age-related differences in raloxifene pharmacokinetics have been identified, but cautionary dosing is advised in both moderate-to-severe renal impairment and in hepatic impairment.38 Nonsteroidal anti-inflammatory drugs (NSAID ...
Therapeutic Drug Monitoring in the Geriatric Patient
... has accompanying package insert recommendation for dosage alterations. No age-related differences in raloxifene pharmacokinetics have been identified, but cautionary dosing is advised in both moderate-to-severe renal impairment and in hepatic impairment.38 Nonsteroidal anti-inflammatory drugs (NSAID ...
... has accompanying package insert recommendation for dosage alterations. No age-related differences in raloxifene pharmacokinetics have been identified, but cautionary dosing is advised in both moderate-to-severe renal impairment and in hepatic impairment.38 Nonsteroidal anti-inflammatory drugs (NSAID ...
Anti-Nicotine Vaccine: An Insight
... Worldwide tobacco usage is the leading cause of preventable death. According to the World Health Organisation, there are 1.2 billion smokers and 5 million tobacco-related deaths annually by causing cardiovascular, respiratory, malignancy diseases, which accounts for 10% global mortality. Nicotine is ...
... Worldwide tobacco usage is the leading cause of preventable death. According to the World Health Organisation, there are 1.2 billion smokers and 5 million tobacco-related deaths annually by causing cardiovascular, respiratory, malignancy diseases, which accounts for 10% global mortality. Nicotine is ...
The Glycine Transporter-1 Inhibitor SSR103800 Displays a
... (Giros et al, 1996). In DAT/ mice, DA levels in the synapse are dramatically elevated and these animals are hyperactive and agitated in behavioral tests. Moreover, DAT/ mice show a deficit in pre-pulse inhibition (PPI) of the startle response (Ralph et al, 2001; Powell et al, 2008), a behavioral ...
... (Giros et al, 1996). In DAT/ mice, DA levels in the synapse are dramatically elevated and these animals are hyperactive and agitated in behavioral tests. Moreover, DAT/ mice show a deficit in pre-pulse inhibition (PPI) of the startle response (Ralph et al, 2001; Powell et al, 2008), a behavioral ...
Psychotropics in Psychiatric Patient – Bipolar disorders
... Therapy initiated gradually eg 100 mg hs Drug given with meals to minimize GI side effects ...
... Therapy initiated gradually eg 100 mg hs Drug given with meals to minimize GI side effects ...
CONCERTA Extended-Release Tablets PRODUCT INFORMATION
... children and adolescents with structural cardiac abonormalities or other serious heart problems. Although some serious heart problems alone carry an increased risk of sudden death, stimulant products generally should not be used in children or adolescents with known serious structural cardiac abnorm ...
... children and adolescents with structural cardiac abonormalities or other serious heart problems. Although some serious heart problems alone carry an increased risk of sudden death, stimulant products generally should not be used in children or adolescents with known serious structural cardiac abnorm ...
Sikh
... structures of the brain (dopaminergic system), thus increasing the risk of addiction for people who start to use heroin. (Ellgren 2006) Correlational, could be from inherent property of marijuana (ex. brain changes), characteristic of users (ex. risk-seekers), or sociocultural associations with mari ...
... structures of the brain (dopaminergic system), thus increasing the risk of addiction for people who start to use heroin. (Ellgren 2006) Correlational, could be from inherent property of marijuana (ex. brain changes), characteristic of users (ex. risk-seekers), or sociocultural associations with mari ...
The Muscarinic Receptor Agonist Xanomeline Has an Antipsychotic
... cortex. The antipsychotic-like effects of xanomeline in the animal models used here suggest that it may be a useful treatment for psychosis. ...
... cortex. The antipsychotic-like effects of xanomeline in the animal models used here suggest that it may be a useful treatment for psychosis. ...
2006; 15: 618–627 pharmacoepidemiology and drug safety
... consensus shifted to acknowledge that opioid analgesics had a legitimate and important role in managing chronic pain.12–15 This change in thinking probably contributed to the dramatic increase in prescriptions written for opioid analgesics from 1990 to 2002.16–18 Opioid analgesics include semisynthe ...
... consensus shifted to acknowledge that opioid analgesics had a legitimate and important role in managing chronic pain.12–15 This change in thinking probably contributed to the dramatic increase in prescriptions written for opioid analgesics from 1990 to 2002.16–18 Opioid analgesics include semisynthe ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.