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Sleep Pharmacology
Sleep Pharmacology

... improved sleep initiation and sleep maintenance, & suppression of SWS They are also anxiolytics, muscle relaxants, and have antianti-seizure properties, useful in nonnon-REM ...
1 Drug Absorption, Distribution and Elimination
1 Drug Absorption, Distribution and Elimination

... and cause nausea, vomiting or haemorrhage (e.g. salicylates, concentrated solutions of most salts). In recent years, these problems have been partially avoided by the use of enteric-coated tablets or slow-release preparations, which only dissolve in the upper small intestine. When drugs are taken or ...
Partial seizures
Partial seizures

...  Idiosyncratic reactions are relatively rare ...
Central Nervous System Activity Studies of Baptisia tinctoria (L.) R
Central Nervous System Activity Studies of Baptisia tinctoria (L.) R

... stress, which lead to social isolation and poor quality of life [1]. More than 650 million people suffer from these mental disorders. Around 6-7% of India’s population suffers from a mental disorder either due to stress, depression, anxiety or any other cause [2]. Psychotherapeutics are noneffective ...
Antiseizure Drugs
Antiseizure Drugs

...  Idiosyncratic reactions are relatively rare ...
Nonsteroidal anti-inflammatory drugs and their effects in the elderly
Nonsteroidal anti-inflammatory drugs and their effects in the elderly

... versus -2 inhibition with older NSAIDs, including etodolac and nabumetone having relatively more selectivity for Cox-2. Concordantly, adverse effects between these more selective agents may be similar to selective Cox-2 inhibitors. A wide variety of NSAIDs are available without prescription with six ...
LSD Possession
LSD Possession

... Albert Hoffman. However, its hallucinogenic effects were unknown until 1943 when Hoffman accidentally consumed some LSD. It was later found that an oral dose of as little as 0.000025 grams (or 25 micrograms, equal in weight to a few grains of salt) is capable of producing rich and vivid hallucinatio ...
Inhalant Abuse - National Drug Court Resource Center
Inhalant Abuse - National Drug Court Resource Center

... Research Report Series Volatile solvents are liquids that vaporize at room temperature. They are found in a multitude of inexpensive, easily available products used for common household and industrial purposes. These include paint thinners and removers, dry-cleaning fluids, degreasers, ...
Silent Cocaine Poisoning - Asia Pacific Journal of Medical Toxicology
Silent Cocaine Poisoning - Asia Pacific Journal of Medical Toxicology

... Background: Cocaine poisoning is known for causing severe clinical effects such as tachycardia, hypertension, agitation and confusion. Absence of clinical manifestations in cocaine poisoning is unusual. Case report: A 26-year old man, known to be a cocaine addict, declared that he was forced by coca ...
Drugs - DBDD
Drugs - DBDD

... More than a quarter (28.2%) of the adult population in Germany has experience with illicit drugs, 7.1% of adults have used drugs in the last 12 months and 3.4% in the last 30 days (Piontek et al. 2016a). Cannabis remains by far the most commonly used illicit drug, amongst both adults and adolescents ...
King Saud University 351 PHL
King Saud University 351 PHL

... Points to be discussed: 1. Agonists & their specific antagonists acting on isolated rabbit intestine. 2. Determine the site of action of unknown drug. Lab work: 1- Material:  Physiological solution: Tyrode’s solution.  Apparatus: Physiograph & thermostatically controlled organ bath.  Preparation: ...
COX-2
COX-2

... • ANALGESIA • ANTI-INFLAMMATORY • ANTI-PYRETIC ...
Two Brain Sites for Cannabinoid Reward
Two Brain Sites for Cannabinoid Reward

... strations of rewarding effects of ⌬9THC appear to be very much dependent on the experimental conditions (Parolaro et al., 2005), the brain sites at which ⌬9THC can trigger these actions are not known. In the present study, we used microinjections into subregions of the VTA and nucleus accumbens to d ...
Antiepilepsy Drugs: pharmacodynamics and
Antiepilepsy Drugs: pharmacodynamics and

... CPS that occur either in isolation or in association with other types of seizures; also indicated for use as sole and adjunctive therapy in the treatment of simple and complex absence seizures in adults and children aged ≥10 years, and adjunctively in adults and children aged ≥10 years with multiple ...
Iodine and Tyrosine
Iodine and Tyrosine

... 2 capsules per day, in divided doses, with meals. ...
This PDF is a selection from an out-of-print volume from... of Economic Research
This PDF is a selection from an out-of-print volume from... of Economic Research

... strategies are needed for reducing cocaine abuse in other settings. Lastly, as in other areas of public health, prevention of cocaine abuse is preferable to having to treat the problem after it has emerged. There ~s a tremendous need for effective strategies to prevent cocaine abuse (Institute of Me ...
Atenolol – Interaction with Other drugs
Atenolol – Interaction with Other drugs

... are similar, their simultaneous use can lend to additive if not synergistic effect. For example when Atenolol is used along with a non-hydropyridine calcium blocker,  profound bradycardia can occur.  Similarly, if two drugs with opposing effects are used together the effect of individual drug may be ...
Strategies for discontinuing benzodiazepines - Gobierno
Strategies for discontinuing benzodiazepines - Gobierno

... population uses benzodiazepines, of which two thirds are female. During 2013, nearly 2000 people received 25 or more prescriptions, and 604 were prescribed 4 or more different benzodiazepines. At least half of people over 85 years and 2% of adolescents, ages 15-19, received at least one benzodiazepi ...
Footprints across the Territory
Footprints across the Territory

... can be created into slightly different drugs and forms such as base (waxy or oily), powder and crystals. Methamphetamine and Amphetamine have similar actions in the body but Meth more easily crosses the brain and has stronger effects and targets dopamine more than MDMA ...
LIPID-LOWERING AGENTS
LIPID-LOWERING AGENTS

... Patients who have had or are at risk for ischemic stroke – statins may be unique among hypolipidemic drugs with respect to stroke reduction ...
Fluvoxamine as a cause of stimulation, mania and
Fluvoxamine as a cause of stimulation, mania and

... Fluvoxamine is a Selective Serotonin Reuptake Inhibitor (SSRI). In the United States, other drugs in this same class include Prozac (fluoxetine), Zoloft (sertraline), Paxil (paroxetine) and, more recently, Celexa (citalopram). Unlike other SSRIs, at the time fluvoxamine was prescribed to Eric Harris ...
Brexpiprazole II: Antipsychotic-Like and Procognitive Effects of a
Brexpiprazole II: Antipsychotic-Like and Procognitive Effects of a

... (novel object recognition [NOR]; 220–240 g at time of testing [Charles River]), and male Long Evans (LE) rats (attentional set-shifting [ID-ED]; 180–280 g at the time of testing [Charles River, Wilmington, MA]) were used. Albino Wistar rats are commonly used for standard behavioral testing of CNS co ...
Opiates
Opiates

... the periaqueductal grey matter and the locus coeruleus. Opiate receptors in these zones (m, d and k), when activated, alter the level of activity in descending pathways from these zones to the spinal cord. The mechanisms of action of opioids at supraspinal levels are still poorly understood. One ide ...
Drugs in pregnancy
Drugs in pregnancy

... during pregnancy. Salicylates readily cross the placenta, but a 2002 meta-analysis did not find evidence of an overall increase in risk of congenital defects associated with first trimester use of aspirin .Although some case-control studies have reported associations between human congenital malform ...
Nebivolol beta blocker equivalence
Nebivolol beta blocker equivalence

... Nebivolol beta blocker equivalence Nebivolol beta blocker equivalence Metoprolol tartrate is approved to control high blood pressure, treat angina symptoms, and improve survival after a heart attack. As a beta blocker, the medication. Calculation of equivalent doses of antihypertensive drugs : β-Blo ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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